Used 2006 Mercedes-Benz E-Class Review

The base E320 is replaced with the E350 for 2006. The new model name indicates a new engine -- a 3.5-liter V6 with 268 hp, a 20-percent increase from the previous E320.

The E-Class has long been a staple of Mercedes-Benz lineup. Although the current car traces its lineage back to 1953 when the Pontoon model was introduced, the term "E-Class" essentially debuted along with the new-for-1986 300E (prior to that, the "E" in various Benz models stood for "Einspritzung," German for "fuel injection").

That somber sedan, propelled by either a gasoline or turbodiesel inline six, quickly developed a reputation for athletic performance and impeccable solidity. Initially, buyers could choose between a sedan and wagon, later on a coupe and convertible were added to the mix. Eventually, a V8 version of the sedan came on line in an attempt to fend off the onslaught of premium-quality and aggressively priced Lexus and Infiniti models. Catering to all needs and wants, an all-wheel-drive version, called the "4Matic," became available, as did the "wolf-in-sheep's-clothing" 500E sedan.

In 1994, Mercedes moved the letters to the front of the numbers to indicate the model series; hence the 300E became the E320. The next generation of the Mercedes-Benz E-Class debuted for 1996 with its eyes wide open. The big, oval headlights took some getting used to, but evidently, luxury car buyers quickly warmed up to the new E, as it was the top-selling car for the company. Once again, six, eight and turbodiesel versions were offered, though the oil burner was discontinued for 2000. Fortunately, the fully redesigned 2003 E-Class sedan didn't stray too far from the previous iteration. Exterior styling isn't dramatically different; the headlamps, though, are sleeker and blend into the body more elegantly than in the past. Overall, the car gives off a sportier image than the sedate outgoing model without losing its elegant demeanor.

For 2004, the E-Class wagons got a fresh start as well, picking up the sleeker bodywork and all of the engineering refinements. Noting increased consumer interest in luxury wagons, Mercedes is offering both V6 and V8 versions this time around. The 4Matic all-wheel-drive system is available as well, and those living in cold climates, should take note that they can now get it on the sedan as well. For 2005 the diesel Benz returned in the E320 CDI model. CDI stands for Common-rail Direct Injection, and this turbodiesel six is notable for its strong performance, excellent fuel mileage and exceptionally quiet and refined operation.

For 2006, the E320 is replaced with the E350, which features a larger V6 with 20-percent more horsepower. One thing that hasn't changed is the high price of admission, as the 2006 Mercedes-Benz E-Class sedans and wagons remain some of the most expensive midsize luxury cars on the market. That said, these are also some of the most capable, most luxurious and safest cars on the road. If you have plenty of money and you're shopping for a luxury car, your local Mercedes-Benz dealership would be a good place to start.

The Mercedes-Benz E-Class is available in both sedan and wagon form in one of three trim levels -- E350, E320 CDI and E500. The E350 and E500 can be had in either body style; the E320 CDI is a sedan only. Standard features on the E350 and E320 CDI include leather upholstery, wood interior trim, 10-way power seats and dual-zone climate control. E500 models add 17-inch wheels, an adaptive suspension, four-zone climate control and an upgraded Bose sound system. A number of high-tech options are available, including the Keyless Go system, self-adjusting active ventilated seats and adaptive cruise control.

The E350 comes with a 3.5-liter V6 rated at 268 horsepower and 258 pound-feet of torque. The diesel engine in the E320 CDI is a 3.2-liter with 201 hp, an impressive 369 lb-ft of torque and a 27 city/37 highway EPA rating. The E500 and its 5.0-liter V8 pump out 302 hp and 339 lb-ft of torque. A five-speed automanual transmission is fitted to each, except the rear-drive E350 and E500, which feature a seven-speed unit. The 4Matic all-wheel-drive system is optional.

In addition to expected features like stability control and head- and torso-protecting side airbags, the Mercedes-Benz E-Class boasts electronic braking. This system provides a more precise interface between the brakes and other active safety systems. Stopping distances are convincingly short, but the brakes can't match the progressive feel of conventional setups. In government crash tests, the E-Class earned four stars (out of five) for frontal impacts and a perfect five stars for side impacts. In IIHS frontal offset crash testing, the midsize Benz was named a "Best Pick" in its class.

The well-appointed cabin features a two-tone dash with wood accents, top-grade materials and nicely dampened controls. One of the most extravagant options is the Drive Dynamic front seats, which not only adapt for comfort but automatically provide additional lateral support during cornering. Two adults can easily fit in the backseat, but larger occupants may find thigh support and foot room in short supply.

The new V6 is a refined unit with plenty of power for most any situation. The 45 state-certified E320 CDI offers outstanding fuel economy with no sacrifice in acceleration compared to the E350. Money no object, the smooth and silent 5.0-liter V8 is also a great choice. All E-Class cars demonstrate exemplary road manners with a comfortable, controlled ride. Although the 2006 Mercedes-Benz E-Class isn't as athletic as BMW's 5 Series, those who like to take the back roads will not be disappointed by the car's grip and response around turns.

This review was written by a member of Edmunds' editorial team of expert car reviewers. Our team drives every car you can buy. We put the vehicles through rigorous testing, evaluating how they drive and comparing them in detail to their competitors.

We're also regular people like you, so we pay attention to all the different ways people use their cars every day. We want to know if there's enough room for our families and our weekend gear and whether or not our favorite drink fits in the cupholder. Our editors want to help you make the best decision on a car that fits your life.