2022 Lexus RX 350 Review

Name: 2022 Lexus RX 350
Brand: Lexus

Price Range: $30,395 - $50,998

2021 Lexus RX 350 F SPORT 4dr SUV Exterior Shown

Good

7.7

out of 10

edmunds TESTED

With its combination of impressive attention to detail, interior appointments and practicality, the 2022 Lexus RX 350 has long been an attractive proposition in the luxury SUV scene. Though its bold styling might be a deterrent to some, the harsh and busy ride of the F Sport might be the RX 350's biggest misstep. The optional Mark Levinson audio system and well-calibrated driver aids help take the edge off any commute.

See all features & specs

See Offers Near Ashburn, VA

2026 Lexus RX

View Offers

Lexus.com

Price & Payment

Select year

Average price: $31,620

Min$

Max$

See listings

Appraise My 2022 Lexus RX 350

Build & Price

Lexus.com

Lexus RX 350 model years

Lexus RX 350 for Sale

Pros

Attractive cabin with top-quality materials and construction
Super smooth ride
Wide cargo bay makes it easy to load items

Cons

Touchpad controller is distracting to use
Real-world fuel economy lags behind estimates

What's new

No significant changes for 2022
Part of the fourth RX generation introduced for 2016

Overview

Written by automotive expert Kurt Niebuhr

9/15/2021

The Lexus RX has long been the quiet and comfortable choice in the luxury crossover SUV segment. The RX has for the most part kept up with the changing demands of the luxury SUV buyer — beyond the standard RX 350, there's a long-wheelbase version (RX 350L) as well as a hybrid variant (RX 450h), both of which are reviewed separately. This current-generation RX 350 is nearing the end of its run — it's been around since the 2016 model year — but it still offers a well-built, comfortable interior and remains a good value for your money.

Continue reading Edmunds Expert Rating below

For sale near Ashburn, VA

695 listings

Sort by:

Price Drop
2022 Lexus RX 350
Base 4dr SUV
$39,300
good price
$2,072 below market
- 56,341 miles
- 5 Seats, 19 City / 26 Hwy MPG
- 42 mi away
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Baltimore, MD
Recent Arrival! 2022 Lexus RX 350, 4D Sport Utility, 3.5L V6 DOHC 24V, 8-Speed Automatic, AWD, Caviar, Black w/NuLuxe Seat Trim, 12.3" Navigation Syst...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN:
2T2HZMDA9NC366227
Stock:
KMBP220294B
Certified Pre-Owned:
No
Listed since:
05-09-2026
2022 Lexus RX 350
Base 4dr SUV
$43,995
fair price
$552 below market
- 28,826 miles
- 5 Seats, 19 City / 26 Hwy MPG
- 60 mi away
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Hanover, PA
Come see this 2022 Lexus RX RX 350. Its Automatic transmission and Regular Unleaded V-6 3.5 L/211 engine will keep you going. This Lexus RX comes equi...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN:
2T2HZMDA9NC312913
Stock:
15855
Certified Pre-Owned:
No
Listed since:
05-07-2026

See all for sale

All the same, it'll be worth your while to research a few other small or midsize luxury SUVs. The BMW X3 and Mercedes-Benz GLC blend modern technology, fuel efficiency and luxury in ways the Lexus can't quite match. And Acura's newly redesigned MDX offers comfort and a lot of standard features. For more details and specifics about the Lexus RX 350, check out our Expert Rating below.

Edmunds Expert Rating

edmunds TESTED

by the Edmunds Experts

Good

7.7

out of 10

We drove the 2022 Lexus RX 350 on our test track and on real roads. Our Edmunds team conducts rigorous independent vehicle testing, driving 500,000 miles a year.

Performance

7.5/10

How does the RX 350 drive? Outright performance isn't the name of the RX 350's game, even in F Sport trim. But when it comes to merging on a highway or overtaking slower traffic, the smooth and powerful V6 engine gets the job done. Accelerating to 60 mph takes 7.9 seconds, which isn't as quick as most competitors but is plenty adequate. More aggressive drivers will want to opt for the all-wheel drive for its superior traction.

The F Sport reduces body roll, but handling isn't really improved. The tires are the main letdown, but the Lexus can still confidently handle a twisty road. The brakes provide easy and smooth stopping power. The transmission is a little too eager to shift to a higher gear, but it does its work almost transparently.

Comfort

8/10

How comfortable is the RX 350? Comfort is paramount in a Lexus, and the RX 350 is generally excellent. The RX 350 can definitely take the edge off a long commute thanks to well-insulated windows, impressively comfortable seats covered in supple leather, and an effective and easy-to-use climate control system.

The only real negative, and it could be a deal-breaker, comes in the F Sport trim. In the attempt to achieve sportier handling, it throws any semblance of a relaxing ride right out the window. Moderately chewed-up roads will bounce and jitter occupants about in a very un-Lexus-like manner, and larger potholes can be jarring. We'd recommend steering clear of the F Sport.

Interior

8/10

How’s the interior? Even though the base of the windshield looks to be pretty far away, the dashboard and all major controls fall easily to hand. The buttons are on the large side, clearly labeled and easy to press, and most everything you touch feels well engineered and well considered. All passengers will appreciate the large square door openings, and there's plenty of room for tall people in the front and the back. Even the panoramic sunroof doesn't take away much headroom.

Many systems can't be fully accessed without using the touchscreen or the accompanying touchpad interface, but we appreciate having a choice. Navigating the menus is relatively simple but can't be done as fluidly as you can in a BMW or a Mercedes.

Technology

7.5/10

How’s the tech? Lexus' Mark Levinson stereos are always a high point, and the big infotainment screen is crisp and appealing. Lexus' Enform app has a handful of useful features, but it only integrates a limited selection of third-party apps. Android Auto and Apple CarPlay smartphone integration operates fine for the most part, though some of our Android users experienced issues with some apps missing and sometimes had no functionality at all. Charging options are available for the first two rows, with a generous six USBs total.

Thanks to the abundance of well-labeled buttons, you can often sidestep the somewhat formal and command-heavy voice control system. Driver aids are well calibrated, and we didn't have any false alarms or overreactions, though we would like the adaptive cruise control to be a bit more responsive to traffic flow.

Storage

8/10

How’s the storage? Thanks to its two-row configuration, there's always a good amount of storage — 18.4 cubic feet — in the trunk of the RX 350. That's not as big as some other midsize SUVs, but it's decent. And with 40/20/40-split folding rear seats, this luxury SUV has flexibility to carry an assortment of goods. It's even rated to tow 3,500 pounds, which, though far from class-leading, is enough for a small trailer with a motorcycle or two.

Passengers get a fair amount of well-thought-out storage for personal items, even including a cupholder whose depth can be adjusted for taller mugs. Child seats will also have ample room for attachment thanks to the large door openings and plenty of rear legroom.

Fuel Economy

6.5/10

How’s the fuel economy? The front-wheel-drive RX350, with an EPA-estimated 23 mpg combined (20 city/27 highway), does little to distinguish itself in a competitive class. Our 115-mile highway-heavy evaluation loop returned just under 22 mpg, and to be honest we expected a bit more. On the plus side, the V6 engine doesn't require premium fuel unlike a lot of its turbocharged rivals.

Value

8/10

Is the RX 350 a good value? Fit and finish on the RX 350 leaves almost nothing to be desired, both inside and out. It's a rare moment when you come in contact with something other than leather or soft-touch plastics. Many manufacturers lack this level of attention to detail. But the price teetered on the edge of $60K for our optioned-up F Sport test vehicle.

Should you be able to go without some optional equipment, the standard RX 350 starts around $45K. We weren't overly impressed by the fuel economy we observed, but the warranties offered are good for the class and there's roadside assistance for four years with unlimited miles.

Wildcard

7/10

Provided you don't spend the money on the misguided F Sport, the RX 350 is an impressively comfortable and serene place to spend your time. All passengers feel immediately at home in its spacious and well-equipped interior, and you'll start to wonder why even the gas pedal feels so good to the bottom of your shoe. The RX simply exudes quality.

But the F Sport gives that serenity a good and constant shaking and manages to upset a fairly luxurious experience. So too does the odd infotainment interface — it's been a source of frustration since its introduction. Thankfully you can get an RX without the stiff suspension and still revel in that excellent Mark Levinson audio system.

Build Your 2026 Lexus RX

At a Glance:

$52,275starting MSRP

Build & Price Lexus.com

2022 Lexus RX 350 trim level differences

The 2022 Lexus RX 350 comes in two trims: base and F Sport. Both are powered by a 3.5-liter V6 (295 horsepower, 267 lb-ft of torque) that's paired to an eight-speed automatic transmission. Front-wheel drive is standard, and all-wheel drive is optional. Feature highlights include: Compare the 2022 Lexus RX 350 trim levels in-depth.

Which RX 350 trim does Edmunds recommend?

We see no reason to stray from the base RX 350 since it offers plenty of available options. To that, we'd add the navigation system, the Mark Levinson audio system and the panoramic sunroof to round out the already luxurious interior. All-wheel drive is available, but we'd recommend steering clear of the F Sport since its firm ride runs counter to the RX's otherwise relaxed demeanor.

Cost to Drive

Monthly estimates based on costs in Virginia

$253/mo

$220/mo

Avg. Midsize SUV

Calculate my fuel costs

See Edmunds pricing data

Has Your Car's Value Changed?

Used car values are constantly changing. Edmunds lets you track your vehicle's value over time so you can decide when to sell or trade in.

Year

Make

Model

See pricing history

Reliability

The 2022 Lexus RX 350 has a 4 years / 50,000 miles basic warranty and no recalls. RepairPal gives it a reliability rating of 4.5 out of 5, ranks it #3 out of 29 among Luxury Midsize SUVs. Below you’ll find our owner reviews.

Reliability Rating by RepairPal

4.5 out of 5 stars4.5/5Excellent

#3 out of 29 among Luxury Midsize SUVs

RepairPal Reliability Ratings are based on the actual cost, frequency, and severity of unscheduled repairs and maintenance on make/model data for select 2008-2022 vehicles. The reliability of a specific vehicle may vary depending on its maintenance and driving history, model year, trim, and features.

Cost

$408/yr

vs. $602/yr
for Average Luxury Midsize SUV

Frequency

0.84x/yr

vs. 1.09x/yr
for Average Luxury Midsize SUV

Severity

6.5%

vs. 9.4%
for Average Luxury Midsize SUV

Recalls

There are no recalls for the 2022 Lexus RX 350

Warranty

4 years / 50,000 miles Basic Warranty

Basic Warranty: 4 years / 50,000 miles
Drivetrain Warranty: 6 years / 70,000 miles
Rust Warranty: 6 years / unlimited miles
Roadside assistance Warranty: 4 years / unlimited miles
Free maintenance Warranty: 1 years / 10,000 miles

Lexus RX 350 Reviews

Owner Reviews

4.1

48 reviews

5(67%)

4(10%)

3(6%)

2(4%)

1(13%)

See all 48 reviews of the Lexus RX 350

Write a vehicle review

Most Helpful Owner Reviews

2022 RX 350 Features & Specs

Trim:

Base

MSRP (New) Excludes Destination Fee	$45,920
Engine Type	Gas
Combined MPG	23 MPG
Cost to Drive	$253/month
Seating	5 seats
Cargo Capacity All Seats In Place	16.0 cu.ft.
Drivetrain	front wheel drive
Warranty	4 years / 50,000 miles

See all features & specs

Safety

Our experts like the RX 350 models:

Lexus Safety System+ 2.0: Bundle includes adaptive cruise control, forward collision mitigation with automatic braking, and lane keeping assist.
Lexus Enform Safety Connect: This system can automatically alert emergency services in the event of a crash or distress. Also includes a stolen vehicle locator.
Panoramic View Monitor: The panoramic rearview camera maximizes the 12.3-inch widescreen display and gives a broad look at what's behind you before you back up.

NHTSA Overall Rating

The National Highway Transportation Safety Administration offers independent analysis.

Frontal Barrier Crash Rating
Overall4 / 5
Driver3 / 5
Passenger4 / 5
Side Crash Rating
Overall5 / 5
Side Barrier Rating
Overall5 / 5
Driver5 / 5
Passenger5 / 5
Combined Side Barrier & Pole Ratings
Front Seat5 / 5
Back Seat5 / 5
Rollover
Rollover4 / 5
Dynamic Test ResultNo Tip
Risk Of Rollover17.9%

IIHS Rating

The Insurance Institute of Highway Safety uses extensive crash tests to determine car safety.

Small Overlap Front Driver-Side Test
Good
Small Overlap Front Passenger-Side Test
Good
Moderate Overlap Front Test – Original
Good
Moderate Overlap Front Test – Updated
Not Tested
Side Impact Test – Original
Good
Side Impact Test – Updated
Not Tested
Roof Strength Test
Good
Rear Crash Protection / Head Restraint
Good