2021 Lexus RX 350

What’s new

  • Blind-spot monitoring and rear cross-traffic alert are standard for 2021
  • Wireless smartphone charging now available
  • Part of the fourth RX generation introduced for 2016

Pros & Cons

  • Attractive cabin with top-quality materials and construction
  • Super smooth ride
  • Advanced safety features come standard
  • Wide cargo bay makes it easy to load items
  • Touchpad controller is distracting to use
  • Real-world fuel economy lags behind estimates
MSRP Starting at
$45,070

Save as much as $1,261
Select your model:

2021 Lexus RX 350 Review

What is the RX 350?

The Lexus RX 350 is a midsize crossover that serves as the bread and butter of Lexus' SUV lineup. Given its well-rounded nature, it's easy to see why so many buyers flock to the RX.

The RX 350 delivers everything you'd expect from a Lexus. That means a supple ride, a silent cabin and high-quality interior materials. Since the RX is a midsize SUV, the cabin is eminently roomy in both rows. The seats are also exceptional, providing hours of drama-free comfort thanks to the soft leather and thick padding. They stand in sharp contrast to those in British and German rivals, which hew toward firmness. All of this RX goodness is available at a lower price than similarly equipped rivals.

The Lexus RX does suffer from a few drawbacks — the dramatic rear roofline reduces ultimate cargo capacity, and the infotainment system is difficult to use. But given its wild popularity, it seems that many buyers are willing to overlook these deficiencies given the RX's excellence in other areas.

Edmunds says

Fresh off a moderate refresh last year, we don't expect any significant changes to the well-rounded Lexus RX 350 for 2021.

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Avaliable in
F SPORT Performance, F SPORT, Base

Consumer reviews

There are no consumer reviews for the 2021 Lexus RX 350.

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    Features & Specs

    4dr SUV features & specs
    4dr SUV
    3.5L 6cyl 8A
    MSRP$45,070
    MPG 20 city / 27 hwy
    SeatingSeats 5
    Transmission8-speed shiftable automatic
    Horsepower295 hp @ 6300 rpm
    See all for sale
    F SPORT 4dr SUV features & specs
    F SPORT 4dr SUV
    3.5L 6cyl 8A
    MSRP$48,550
    MPG 20 city / 27 hwy
    SeatingSeats 5
    Transmission8-speed shiftable automatic
    Horsepower295 hp @ 6300 rpm
    See all for sale
    F SPORT 4dr SUV AWD features & specs
    F SPORT 4dr SUV AWD
    3.5L 6cyl 8A
    MSRP$49,950
    MPG 19 city / 26 hwy
    SeatingSeats 5
    Transmission8-speed shiftable automatic
    Horsepower295 hp @ 6300 rpm
    See all for sale
    F SPORT 4dr SUV AWD w/Handling Package features & specs
    F SPORT 4dr SUV AWD w/Handling Package
    3.5L 6cyl 8A
    MSRP$52,350
    MPG 19 city / 26 hwy
    SeatingSeats 5
    Transmission8-speed shiftable automatic
    Horsepower295 hp @ 6300 rpm
    See all for sale
    See all 2021 Lexus RX 350 features & specs

    Safety

    NHTSA Overall Rating

    The National Highway Transportation Safety Administration offers independent analysis.

    Frontal Barrier Crash RatingRating
    OverallNot Rated
    DriverNot Rated
    PassengerNot Rated
    Side Crash RatingRating
    Overall5 / 5
    Side Barrier RatingRating
    Overall5 / 5
    Driver5 / 5
    Passenger5 / 5
    Combined Side Barrier & Pole RatingsRating
    Front Seat5 / 5
    Back Seat5 / 5
    RolloverRating
    Rollover4 / 5
    Dynamic Test ResultNo Tip
    Risk Of Rollover17.9%

    IIHS Rating

    The Insurance Institute of Highway Safety uses extensive crash tests to determine car safety.

    Side Impact Test
    Good
    Roof Strength Test
    Good
    Rear Crash Protection / Head Restraint
    Good
    IIHS Small Overlap Front TestNot Tested
    Moderate Overlap Front Test
    Good

    Related RX 350 Articles

    FAQ

    Is the Lexus RX 350 a good car?

    The Edmunds experts tested the 2021 RX 350 both on the road and at the track. You probably care about Lexus RX 350 fuel economy, so it's important to know that the RX 350 gets an EPA-estimated 22 mpg to 23 mpg, depending on the configuration. What about cargo capacity? When you're thinking about carrying stuff in your new car, keep in mind that the RX 350 has 16.0 cubic feet of trunk space. And then there's safety and reliability. Edmunds has all the latest NHTSA and IIHS crash-test scores, plus industry-leading expert and consumer reviews to help you understand what it's like to own and maintain a Lexus RX 350. Learn more

    What's new in the 2021 Lexus RX 350?

    According to Edmunds’ car experts, here’s what’s new for the 2021 Lexus RX 350:

    • Blind-spot monitoring and rear cross-traffic alert are standard for 2021
    • Wireless smartphone charging now available
    • Part of the fourth RX generation introduced for 2016
    Learn more

    Is the Lexus RX 350 reliable?

    To determine whether the Lexus RX 350 is reliable, read Edmunds' authentic consumer reviews, which come from real owners and reveal what it's like to live with the RX 350. Look for specific complaints that keep popping up in the reviews, and be sure to compare the RX 350's average consumer rating to that of competing vehicles. Learn more

    Is the 2021 Lexus RX 350 a good car?

    There's a lot to consider if you're wondering whether the 2021 Lexus RX 350 is a good car. Safety scores, fuel economy, cargo capacity and feature availability should all be factors in determining whether the 2021 RX 350 is a good car for you. Check back soon for the official Edmunds Rating from our expert testing team Learn more

    How much should I pay for a 2021 Lexus RX 350?

    The least-expensive 2021 Lexus RX 350 is the 2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A). Including destination charge, it arrives with a Manufacturer's Suggested Retail Price (MSRP) of about $45,070.

    Other versions include:

    • 4dr SUV (3.5L 6cyl 8A) which starts at $45,070
    • F SPORT 4dr SUV (3.5L 6cyl 8A) which starts at $48,550
    • F SPORT 4dr SUV AWD (3.5L 6cyl 8A) which starts at $49,950
    • F SPORT 4dr SUV AWD w/Handling Package (3.5L 6cyl 8A) which starts at $52,350
    • F SPORT 4dr SUV w/Handling Package (3.5L 6cyl 8A) which starts at $50,950
    • 4dr SUV AWD (3.5L 6cyl 8A) which starts at $46,470
    Learn more

    What are the different models of Lexus RX 350?

    If you're interested in the Lexus RX 350, the next question is, which RX 350 model is right for you? RX 350 variants include 4dr SUV (3.5L 6cyl 8A), F SPORT 4dr SUV (3.5L 6cyl 8A), F SPORT 4dr SUV AWD (3.5L 6cyl 8A), and F SPORT 4dr SUV AWD w/Handling Package (3.5L 6cyl 8A). For a full list of RX 350 models, check out Edmunds’ Features & Specs page. Learn more

    More about the 2021 Lexus RX 350

    2021 Lexus RX 350 Overview

    The 2021 Lexus RX 350 is offered in the following submodels: RX 350 SUV. Available styles include 4dr SUV (3.5L 6cyl 8A), F SPORT 4dr SUV (3.5L 6cyl 8A), F SPORT 4dr SUV AWD (3.5L 6cyl 8A), F SPORT 4dr SUV AWD w/Handling Package (3.5L 6cyl 8A), F SPORT 4dr SUV w/Handling Package (3.5L 6cyl 8A), and 4dr SUV AWD (3.5L 6cyl 8A).

    What do people think of the 2021 Lexus RX 350?

    Consumer ratings and reviews are also available for the 2021 Lexus RX 350 and all its trim types. Edmunds consumer reviews allow users to sift through aggregated consumer reviews to understand what other drivers are saying about any vehicle in our database. Detailed rating breakdowns (including performance, comfort, value, interior, exterior design, build quality, and reliability) are available as well to provide shoppers with a comprehensive understanding of why customers like the 2021 RX 350.

    Edmunds Expert Reviews

    Edmunds experts have compiled a robust series of ratings and reviews for the 2021 Lexus RX 350 and all model years in our database. Our rich content includes expert reviews and recommendations for the 2021 RX 350 featuring deep dives into trim levels and features, performance, mpg, safety, interior, and driving. Edmunds also offers expert ratings, road test and performance data, long-term road tests, first-drive reviews, video reviews and more.

    Our Review Process

    This review was written by a member of Edmunds' editorial team of expert car reviewers. Our team drives every car you can buy. We put the vehicles through rigorous testing, evaluating how they drive and comparing them in detail to their competitors.

    We're also regular people like you, so we pay attention to all the different ways people use their cars every day. We want to know if there's enough room for our families and our weekend gear and whether or not our favorite drink fits in the cupholder. Our editors want to help you make the best decision on a car that fits your life.

    What's a good price for a New 2021 Lexus RX 350?

    2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)

    The 2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) can be purchased for less than the Manufacturer’s Suggested Retail Price (aka MSRP) of $50,975. The average price paid for a new 2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) is trending $1,214 below the manufacturer’s MSRP.

    Edmunds members save an average of $1,214 by getting upfront special offers. The estimated special offer price in your area is $49,761.

    The average savings for the 2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) is 2.4% below the MSRP.

    Available Inventory:

    We are showing 1 2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) vehicle(s) available in the Ashburn area.

    2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A)

    The 2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) can be purchased for less than the Manufacturer’s Suggested Retail Price (aka MSRP) of $47,495. The average price paid for a new 2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) is trending $1,261 below the manufacturer’s MSRP.

    Edmunds members save an average of $1,261 by getting upfront special offers. The estimated special offer price in your area is $46,234.

    The average savings for the 2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) is 2.7% below the MSRP.

    Available Inventory:

    We are showing 5 2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) vehicle(s) available in the Ashburn area.

    Which 2021 Lexus RX 350s are available in my area?

    Shop Edmunds' car, SUV, and truck listings of over 6 million vehicles to find a cheap new, used, or certified pre-owned (CPO) 2021 Lexus RX 350 for sale near. There are currently 17 new 2021 RX 350s listed for sale in your area, with list prices as low as $49,120 and mileage as low as 0 miles. Simply research the type of car you're interested in and then select a car from our massive database to find cheap vehicles for sale near you. Once you have identified a used vehicle you're interested in, check the AutoCheck vehicle history reports, read dealer reviews, and find out what other owners paid for the 2021 Lexus RX 350.

    Can't find a new 2021 Lexus RX 350s you want in your area? Consider a broader search.

    Find a new Lexus RX 350 for sale - 3 great deals out of 6 listings starting at $21,830.

    Find a new Lexus for sale - 4 great deals out of 9 listings starting at $12,711.

    Why trust Edmunds?

    Edmunds has deep data on over 6 million new, used, and certified pre-owned vehicles, including rich, trim-level features and specs information like: MSRP, average price paid, warranty information (basic, drivetrain, and maintenance), features (upholstery, bluetooth, navigation, heated seating, cooled seating, cruise control, parking assistance, keyless ignition, satellite radio, folding rears seats ,run flat tires, wheel type, tire size, wheel tire, sunroof, etc.), vehicle specifications (engine cylinder count, drivetrain, engine power, engine torque, engine displacement, transmission), fuel economy (city, highway, combined, fuel capacity, range), vehicle dimensions (length, width, seating capacity, cargo space), car safety, true cost to own. Edmunds also provides tools to allow shopper to compare vehicles to similar models of their choosing by warranty, interior features, exterior features, specifications, fuel economy, vehicle dimensions, consumer rating, edmunds rating, and color.

    Should I lease or buy a 2021 Lexus RX 350?

    Is it better to lease or buy a car? Ask most people and they'll probably tell you that car buying is the way to go. And from a financial perspective, it's true, provided you're willing to make higher monthly payments, pay off the loan in full and keep the car for a few years. Leasing, on the other hand, can be a less expensive option on a month-to-month basis. It's also good if you're someone who likes to drive a new car every three years or so.

    Check out Lexus lease specials