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6,678 listings
- $28,980great price$5,458 below market
- 59,357 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Willow Grove, PA
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Located in Willow Grove, PA / 969 miles away from Des Moines, IA
This 2018 Lexus RX 350 in White combines refined luxury with practical capability ready to serve your driving needs with confidence and style.- Blin...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA1JC145433
- Stock:
- R26546A
- Certified Pre-Owned:
- No
- Listed since:
- 08-12-2026
- $26,973good price$1,853 below market
- 76,797 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Santa Ana, CA
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Located in Santa Ana, CA / 1,427 miles away from Des Moines, IA
Preowned 2018 Lexus RX 350. Well equipped with 10-Way Power NuLuxe-trimmed Front Seats, Rain Sensing Windshield Wipers, and much more. Apply online, o...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA6JC136680
- Stock:
- 826176
- Certified Pre-Owned:
- No
- Listed since:
- 08-18-2026
- $25,000good price$2,256 below market
- 92,699 miles
- 5 Seats, 20 City / 27 Hwy MPG
- Raleigh, NC
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Located in Raleigh, NC / 890 miles away from Des Moines, IA
Discover unmatched choice at Westgate Chrysler Jeep Dodge Ram in Raleigh, home to a huge lineup of new vehicles and one of the largest used-car invent...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCAXJC102787
- Stock:
- 35868XP
- Certified Pre-Owned:
- No
- Listed since:
- 06-09-2026
- Price Drop$26,400great price$5,033 below market
- 78,791 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Allentown, PA
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Located in Allentown, PA / 946 miles away from Des Moines, IA
Thank you for choosing AutoPROVED, where Cars Cost Less and home of No Haggle Pricing. All of our vehicles go through a RIGOROUS 118pt inspection and ...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA3JC144123
- Stock:
- A2609182
- Certified Pre-Owned:
- No
- Listed since:
- 09-18-2026
- $27,998good price$2,358 below market
- 62,232 miles
- 5 Seats, 20 City / 27 Hwy MPG
- Henderson, NV
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Located in Henderson, NV / 1,211 miles away from Des Moines, IA
This 2018 Lexus RX 350 combines luxury and capability in a refined SUV package. With 62,232 miles on the odometer, this white exterior with black leat...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA6JC095756
- Stock:
- A5868
- Certified Pre-Owned:
- No
- Listed since:
- 09-04-2026
- Price Drop$26,333great price$3,440 below market
- 68,154 miles
- 5 Seats, 20 City / 27 Hwy MPG
- Springfield, MO
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Located in Springfield, MO / 302 miles away from Des Moines, IA
This 2018 Lexus RX 350 delivers refined performance and thoughtful design in an elegant gray exterior. With a robust 3.5L V6 engine paired with an 8-s...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA1JC115251
- Stock:
- 3115251
- Certified Pre-Owned:
- No
- Listed since:
- 08-31-2026
- Price Drop$30,990good price$2,936 below market
- 33,105 miles
- 5 Seats, 20 City / 27 Hwy MPG
- In-stock online
- Delivery available*
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Located in Richmond, VA / 892 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA4JC101361
- Stock:
- 2004952588
- Certified Pre-Owned:
- No
- Listed since:
- 06-22-2026
- Price Drop$25,059fair price$168 above market
- 95,428 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Arlington, MA
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Located in Arlington, MA / 1,150 miles away from Des Moines, IA
This 2018 Lexus RX 350 combines sophisticated styling with reliable performance. With a 3.5L V6 engine delivering 19 city and 26 highway MPG, paired w...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA7JC165394
- Stock:
- HR137X
- Certified Pre-Owned:
- No
- Listed since:
- 08-28-2026
- Price Drop$27,999fair price$77 above market
- 84,683 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Glens Falls, NY
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Located in Glens Falls, NY / 1,021 miles away from Des Moines, IA
This stunning 2018 Lexus RX 350 F Sport delivers premium luxury with athletic performance. With its powerful 3.5L V6 engine and all-wheel drive, this ...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA8JC147213
- Stock:
- 30854BB
- Certified Pre-Owned:
- No
- Listed since:
- 08-21-2026
- New Listing$32,998fair price$254 above market
- 41,928 miles
- 5 Seats, 20 City / 27 Hwy MPG
- In-stock online
- Transfer available*
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Located in Tucson, AZ / 1,151 miles away from Des Moines, IA
Wanna drive? CarMax puts you in the driver's seat-and that includes transparency and pricing without document or processing fees. Certain cars may hav...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA1JC099679
- Stock:
- 70273602
- Certified Pre-Owned:
- No
- $30,495fair price$90 below market
- 67,332 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Milford, OH
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Located in Milford, OH / 518 miles away from Des Moines, IA
*Vehicle Details* Refined, capable, and crafted for everyday luxury, this 2018 Lexus RX 350 Base is a standout choice for drivers seeking a premium mi...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCAXJC152316
- Stock:
- B8152316
- Certified Pre-Owned:
- No
- Listed since:
- 06-27-2026
- $27,990good price
- 79,757 miles
- 5 Seats, 20 City / 27 Hwy MPG
- In-stock online
- Delivery available*
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Located in San Antonio, TX / 884 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA7JC110460
- Stock:
- 3006614574
- Certified Pre-Owned:
- No
- Listed since:
- 09-14-2026
- $26,980fair price$268 below market
- 88,186 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Cincinnati, OH
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Located in Cincinnati, OH / 506 miles away from Des Moines, IA
RX 350 trim, Eminent White Pearl exterior and BLACK interior. EPA 26 MPG Hwy/19 MPG City!KEY FEATURES INCLUDEAll Wheel Drive, Back-Up Camera, Satellit...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA3JC164419
- Stock:
- B78445
- Certified Pre-Owned:
- No
- Listed since:
- 08-29-2026
- Price Drop$29,609fair price$780 below market
- 64,706 miles
- 5 Seats, 20 City / 27 Hwy MPG
- Oklahoma City, OK
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Located in Oklahoma City, OK / 464 miles away from Des Moines, IA
This 2018 Lexus RX 350 in silver offers the luxury and reliability that defines the RX line. With just over 64,700 miles, this well-maintained SUV del...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCAXJC100196
- Stock:
- RJT00196
- Certified Pre-Owned:
- No
- Listed since:
- 10-01-2026
- $19,170good price$1,767 below market
- 149,005 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Brooklyn, NY
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Located in Brooklyn, NY / 1,019 miles away from Des Moines, IA
Looking for a quality used car? Here's why Lexus of Brooklyn is your top choice: Quality Assurance: Rigorous inspections ensure top-notch quality and ...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA2JC158014
- Stock:
- BX24378
- Certified Pre-Owned:
- No
- Listed since:
- 09-11-2026
- $26,590good price
- 87,739 miles
- 5 Seats, 19 City / 26 Hwy MPG
- In-stock online
- Delivery available*
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Located in San Antonio, TX / 884 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA0JC147030
- Stock:
- 3006626779
- Certified Pre-Owned:
- No
- Listed since:
- 09-16-2026
- Price Drop
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Located in Pembroke Pines, FL / 1,315 miles away from Des Moines, IA
2018 Lexus RX 350 Mica !!!*** HURRY ***!!!, *!*!*! DON'T MISS OUT !*!*!*, ** BEST COLOR COMBINATION **, 3.329 Axle Ratio, 4-Wheel Disc Brakes, 9 Speak...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA1JC112396
- Stock:
- 26436302
- Certified Pre-Owned:
- No
- Listed since:
- 08-28-2026
- Price Drop$20,085good price$1,182 below market
- 133,999 miles
- 5 Seats, 19 City / 26 Hwy MPG
- In-stock online
- Delivery available*
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Located in Verona, NJ / 1,005 miles away from Des Moines, IA
CarFax No Accidents Reported,Back-Up Camera,Blind Spot Monitor,Bluetooth,Hands-Free Liftgate,Heated Seats,Heated Seats,Heated Steering Wheel,Keyless S...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA8JC157367
- Stock:
- JC157367J
- Certified Pre-Owned:
- No
- Price Drop$29,187fair price$1,740 below market
- 46,663 miles
- 5 Seats, 20 City / 27 Hwy MPG
- Charlotte, NC
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Located in Charlotte, NC / 820 miles away from Des Moines, IA
2018 Lexus RX 350 Black Leather, Accessory Package, Alloy Wheel Locks, Cargo Net, Carpet Cargo Mat, Key Gloves, Power Tilt & Slide Moonroof.Odometer ...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA1JC094191
- Stock:
- LD94191
- Certified Pre-Owned:
- No
- Listed since:
- 08-28-2026
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Located in Plano, TX / 615 miles away from Des Moines, IA
Single owner, Fully Loaded, Drives great, Great first ride, Non-smoker owner, Vehicle Runs Well, Smooth ride, Always parked indoors, Clean Title, Leat...
- Features and Specs:
- 23 Combined MPG (20 City/27 Highway)
- Listing Information:
- VIN:
- 2T2ZZMCA7JC100933
- Stock:
- 100933
- Certified Pre-Owned:
- No
- New Listing$26,796good price$1,297 below market
- 90,094 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Elmhurst, IL
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Located in Elmhurst, IL / 291 miles away from Des Moines, IA
This 2018 Lexus RX 350 combines refined luxury with capable all-wheel-drive performance. Finished in sophisticated Nebula Gray Pearl with a Stratus Gr...
- Features and Specs:
- 22 Combined MPG (19 City/26 Highway)
- Listing Information:
- VIN:
- 2T2BZMCA9JC147365
- Stock:
- K27385A
- Certified Pre-Owned:
- No
- Listed since:
- 09-09-2026
Showing 1 - 21 out of 6,678 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Many great features but. . .
Kathy, 12/30/2020
2018 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A)
This was my first Lexus and I was excited about purchasing the 2018 RX 350. It had been a leased vehicle at the dealership for a year. I love many things about the car -- it has a nice ride on the interstate, love the design and overall looks. My biggest disappointment is the erratic nature of the transmission as you try to accelerate, especially at lower speeds. I had my car serviced … several times for other things (recalls, scheduled maintenance, etc.) and always had them look at why my acceleration was not smooth. Finally, after having them look at it for a third time, the service manager was honest with me and said they had changed the engine/transmission on the 2018 and later models. He explained that the engine was designed to constantly be looking for the best gear/speed/rpm, etc. to get the best gas mileage. I had been given a 2017 RX 350 courtesy car while mine was in the shop and I'll have to say that I felt it was a much smoother ride, smoother acceleration, quieter engine and it even felt heavier. I still enjoy my 2018 but I will certainly be much more careful if I purchase another Lexus. I wasn't prepared for it to be a somewhat disappointing experience after paying what I felt was a premium price.
FAQ
What is a good price for a used 2018 Lexus RX 350?
- According to Edmunds.com's True Market Value calculations, the retail price of a used 2018 Lexus RX 350's most popular trim, in great condition with 60,000 miles on its odometer, is $32,637. Prices vary by trim, region and options included.
What engine and transmission does the 2018 Lexus RX 350 come with?
- The 2018 Lexus RX 350 comes with a 3.5-liter V6 engine (295 horsepower, 267 pound-feet of torque), and an eight-speed automatic transmission.
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