Skip to main content
Skip to Filters
378 listings
  • New Listing
    • 25,029 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to VA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sacramento, CA / 2,243 miles away from Roanoke, VA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC086529
    Stock: 26945902
    Certified Pre-Owned: No

  • New Listing
    • 23,244 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hoffman Lexus (497 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in East Hartford, CT / 497 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA6JC026041
    Stock: S9029665A
    Certified Pre-Owned: No
    Listed since: 06-01-2025

  • Price Drop
    • 48,654 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tim Short Ford of LaFollette (241 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in La Follette, TN / 241 miles away from Roanoke, VA

    **ACCIDENT FREE/AUTOCHECK CERTIFIED**, **BLUETOOTH**, **FAMILY FRIENDLY**, **HEATED MIRRORS**, **HEATED STEERING WHEEL**, **HEATED/COOLED SEATS**, **K...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA9NC073780
    Stock: P7831A
    Certified Pre-Owned: No
    Listed since: 05-12-2025

    • 37,131 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Rallye Lexus (420 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Glen Cove, NY / 420 miles away from Roanoke, VA

    CALL RALLYE LEXUS TODAY FOR A TEST DRIVE. FULLY RECONDITIONED AT OUR BEAUTIFUL STATE-OF-THE-ART FACILITY BY OUR #1 RALLYE LEXUS CERTIFIED TECHNICIANS ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC083670
    Stock: U26707
    Certified Pre-Owned: Yes
    Listed since: 05-22-2025

    • 18,659 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Southampton (477 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Southampton, NY / 477 miles away from Roanoke, VA

    **TRUE VALUE PRICED! NO DOWN PAYMENT REQUIRED NO DEALER FEESEVER**, NO HIDDEN DEALER FEES!!!, REMAINDER OF FACTORY WARRANTY, INCLUDES WARRANTY, CLEAN ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC080395
    Stock: 9010S
    Certified Pre-Owned: No
    Listed since: 04-15-2025

    • 92,609 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • DA Motors (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Philadelphia, PA / 329 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA5JC026595
    Stock: 21394
    Certified Pre-Owned: No

  • Price Drop
    • 65,262 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Sheehy Lexus of Annapolis (224 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Annapolis, MD / 224 miles away from Roanoke, VA

    F-SPORT, HEATED & VENTILATED FRONT SEATS, PANO ROOF, NAVIGATION, and BLIND SPOT, Memory seat, Power driver seat, Power steering, Power windows, Premiu...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA6JC024256
    Stock: M40396A
    Certified Pre-Owned: No
    Listed since: 05-01-2025

  • New Listing
    • 54,520 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Phoenix, AZ / 1,817 miles away from Roanoke, VA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA4JC027091
    Stock: 2003760618
    Certified Pre-Owned: No
    Listed since: 05-23-2025

  • New Listing
    • 46,141 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • North Coast Subaru (420 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Glen Cove, NY / 420 miles away from Roanoke, VA

    This 2022 Lexus RX 450h F SPORT Appearance You will love great options like Hybrid, All Wheel Drive, Stability Control, WIFI Hotspot, Rear Cross Traff...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA1NC072770
    Stock: HHU58723
    Certified Pre-Owned: No
    Listed since: 04-22-2025

    • 71,274 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • TJ Auto (395 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Brooklyn, NY / 395 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC084536
    Stock: 084536
    Certified Pre-Owned: No
    Listed since: 01-17-2025

    • 25,327 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Auto Lenders of Egg Harbor Township (326 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Egg Harbor, NJ / 326 miles away from Roanoke, VA

    CertificationThis Auto Lenders Certified 2022 Lexus RX 450h has passed our rigorous 110 pt inspection. All Auto Lenders Certified cars are guaranteed ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA3NC090908
    Stock: NC090908
    Certified Pre-Owned: No
    Listed since: 05-24-2025

  • New Listing
    • 130,040 miles
    • 2 accidents, 2 owners, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Capitol Auto (125 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Raleigh, NC / 125 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA2JC022780
    Stock: P022780
    Certified Pre-Owned: No
    Listed since: 01-22-2025

  • New Listing
    Stock photo**
    • 30,126 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Preston Hyundai of Millsboro (269 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Millsboro, DE / 269 miles away from Roanoke, VA

    3.5L V6 DOHC VVT-i 24V, AWD. 2022 Lexus RX 450h Recent Arrival! 31/28 City/Highway MPG 3.5L V6 DOHC VVT-i 24V SilverWE ARE OPEN FOR ALL YOUR SALES AND...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA8NC082725
    Stock: DXHM086A
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • New Listing
    $25,999
    great price
    $4,160 below market
    • 86,435 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Autonomous Auto Group (343 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Marietta, GA / 343 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA0HC013845
    Stock: HC013845M
    Certified Pre-Owned: No
    Listed since: 05-09-2025

    • 51,865 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Just Whips (83 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Greensboro, NC / 83 miles away from Roanoke, VA

    Just Whips 2 Sales Dept 3930 US 220 S Madison, NC 27025 3**-2**-8*** 2018 Lexus RX450H51,XXX MilesClean and Clear TitleAutomatic with AWDLoaded with n...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA7JC022077
    Stock: 022077
    Certified Pre-Owned: No
    Listed since: 04-10-2025

  • Stock photo**
    • 37,331 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Burlington Chrysler Dodge Jeep Ram (334 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Burlington, NJ / 334 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC081249
    Stock: PJ0932
    Certified Pre-Owned: No
    Listed since: 05-14-2025

  • New Listing
    Stock photo**
    • 68,342 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tom Roush Lincoln (377 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fishers, IN / 377 miles away from Roanoke, VA

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V**ONE OWNER**, **NO ACCIDENTS**, **LEATHER SEATS**, **PANORAMIC SUNROOF/MOONROOF**...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC083161
    Stock: L25096A
    Certified Pre-Owned: No
    Listed since: 05-31-2025

    • 67,630 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Grand Motorcars Kennesaw (344 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Kennesaw, GA / 344 miles away from Roanoke, VA

    Vehicle Overview 3.5L V6 DOHC VVT-i 24V, AWD, Circuit Red Artificial Leather, Accessory Package, Black Outer Mirrors, Black Wheel Locks, Cargo Net, Ca...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA5NC087918
    Stock: NC087918
    Certified Pre-Owned: No
    Listed since: 04-27-2025

    • 87,855 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Nashville (386 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Nashville, TN / 386 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXNC090081
    Stock: P6415
    Certified Pre-Owned: No
    Listed since: 05-10-2025

  • New Listing
    Stock photo**
    • 20,254 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Burdick Lexus (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cicero, NY / 454 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1NC088817
    Stock: 1C51761D
    Certified Pre-Owned: No
    Listed since: 06-02-2025

  • New Listing
    • 28,393 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Bob Johnson Resale Center (427 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Rochester, NY / 427 miles away from Roanoke, VA

    Rear Back-Up Camera, Bluetooth, Hands Free, 3.5L V6 DOHC VVT-i 24V, AWD, Parchment Semi-Aniline Le.31/28 City/Highway MPG Priced below KBB Fair Purcha...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA8NC091098
    Stock: XL25914
    Certified Pre-Owned: No
    Listed since: 04-23-2025

Showing 190 - 210 out of 378 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (15%)
  • 3 star
    (12%)
  • 2 star
    (3%)
  • 1 star
    (3%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Report abuse

Used 2022 Lexus RX 450h in Roanoke, VA Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$30,519$31,622$32,770
Clean$30,113$31,184$32,299
Average$29,435$30,454$31,514
Rough$28,554$29,505$30,493

The average list price of a used 2022 Lexus RX 450h in Roanoke, Virginia is $41,508. The average mileage on a used Lexus RX 450h 2022 for sale in Roanoke, Virginia is 53,149. Based on the average mileage of 53,149 for used 2022 Lexus RX 450h for sale in Roanoke, VA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Roanoke, Virginia to be $29,435.

Filters
Skip to Results

Applied Filters4Active

Select Buying Experience

Location

Search radius500 miles
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Body Type

Trim

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details


* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.