We carefully selected the RX 350 on reliability, resale and original price and have been very pleased with the vehicle. We bought a new E-350 Benz about the same time, paid $12K more, and got less value than the Lexus. The Lexus navigation and accessories are touch-screen, all the controls are easily accessible and although a very complex machine, is user friendly. The Benz and a new BMW 5-series in our family require a degree in computer science and a full stop to do the same thing the Lexus system does. Sensible driving gets 20 mpg in local traffic.
Absolutely love the included Bluetooth, backing-up video display, and the power rear door. The additional left-side driver's dash cupholder is pure design genius.
You have to look hard to find flaws in this vehicle. The only feature I would change is to allow the owner to program more programming access to features like the single button door unlock, headlamp on duration, etc. All these changes must be made by the dealer.