I bought this van used, with 180,000 miles on it, and it ran like new then. Now I have 260000 miles on it and it still runs very well, there is some slight engine(valve train)noise, but I turn up the radio and it goes away. I am very religious about oil and fluid changes, which will extend the life of any vehicle, but this is the 4th GM van I have driven over the 200k mile mark, one went over 300k. It has the 4.3 ltr V6/auto and averages 22mpg highway empty,which isn't often, it's a WORK TRUCK. The only things I have replaced:waterpump(started leaking 135m out/got me home), exhaust-cat back, brakepads/shoes,tires,and driver's door latch. Even the side sliding door works with little effort.
Heating and Air Conditioning systems, both work great which makes my work day much easier. Everything under the van is easily reached for maintainance, except the trans pan, you need to drop the X-member to change the fluid/filter, but only 2 bolts for that. A real working man's Van
As with all GM vans of this design, the windshield area rusts. I beleive this has been attended to in the newer body style.