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2,210 listings
  • Price Drop
    $38,426
    good price
    $1,423 below market
    • 38,722 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of North Olmsted (317 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in North Olmsted, OH / 317 miles away from Syracuse, NY

    BACK-UP CAMERA, BLUETOOTH HANDS FREE PHONE, CERTIFIED, HEATED SEATS, LEATHER, NAVIGATION, NO ACCIDENTS, PANORAMIC ROOF, WORRY FREE PRICING... WORRY FR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB0NB038764
    Stock: M8894
    Certified Pre-Owned: Yes
    Listed since: 04-04-2025

  • New Listing
    • 28,999 miles
    • No accidents, 1 owner, personal use
    • 7 Seats, 21 City / 28 Hwy MPG
    • Mercedes-Benz Manhattan (193 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in New York, NY / 193 miles away from Syracuse, NY

    Certified. Clean CARFAX. 21/28 City/Highway MPGMercedes-Benz Manhattan features a 330,000 square foot state-of-the-art facility, knowledgeable staff, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: W1KZH6AB4NB032521
    Stock: 251575A
    Certified Pre-Owned: Yes
    Listed since: 03-28-2025

  • New Listing
    $41,599
    good price
    $1,275 below market
    • 25,143 miles
    • No accidents, 2 owners, personal use only
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of Hunt Valley (249 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cockeysville, MD / 249 miles away from Syracuse, NY

    Nautical Blue MetallicSun/MoonroofNavigation SystemKeyless StartThis vehicle includes a Money-Back Guarantee* and passed our precise inspection ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB2NB063617
    Stock: NB063617
    Certified Pre-Owned: Yes
    Listed since: 05-30-2025

  • New Listing
    Photos not available
    $32,352
    good price
    $1,935 below market
    • 60,094 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Turn Auto Mall (204 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in New Hyde Park, NY / 204 miles away from Syracuse, NY

    Boasts 29 Highway MPG and 21 City MPG! This MERCEDES-BENZ E-CLASS delivers a Intercooled Turbo Premium Unleaded I-4 2.0 L/121 engine powering this Aut...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB9NB028721
    Stock: TU2068
    Certified Pre-Owned: No
    Listed since: 05-23-2025

  • Price Drop
    • 35,440 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of North Olmsted (317 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in North Olmsted, OH / 317 miles away from Syracuse, NY

    BACK-UP CAMERA, BLUETOOTH HANDS FREE PHONE, CERTIFIED, HEATED SEATS, LEATHER, NAVIGATION, NO ACCIDENTS, PANORAMIC ROOF, WORRY FREE PRICING... WORRY FR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB6NB010340
    Stock: M153874A
    Certified Pre-Owned: Yes
    Listed since: 04-02-2025

  • New Listing
    • 27,827 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of Paramus (179 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Paramus, NJ / 179 miles away from Syracuse, NY

    Priced below KBB Fair Purchase Price! Certified. Recent Arrival! 2022 Mercedes-Benz E-Class E 350 4MATIC® Obsidian Black Metallic 4MATIC®, 8 Speaker...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB3NB035115
    Stock: NB035115P
    Certified Pre-Owned: Yes
    Listed since: 05-27-2025

  • $23,749
    good price
    $918 below market
    • 45,503 miles
    • 1 accident, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • Drive World (207 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Woodbury, NY / 207 miles away from Syracuse, NY

    Your trusted destination for quality pre-owned vehicles! We,re proud to serve the community and beyond with a wide selection of reliable, well-maintai...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB6LA840500
    Stock: 180DW
    Certified Pre-Owned: No
    Listed since: 05-02-2025

  • $29,900
    fair price
    $1,058 above market
    • 58,548 miles
    • No accidents, 2 owners, personal use only
    • 22 City / 30 Hwy MPG
    • Land Rover Glen Cove (200 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Glen Cove, NY / 200 miles away from Syracuse, NY

    2020 E-Class Polar White AMG� Body Styling, AMG� Line Exterior, Lowered Suspension w/Selective Damping System, Night Package, Perforated Front Brake D...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: WDDZF8EB2LA713310
    Stock: 4845RU
    Certified Pre-Owned: No
    Listed since: 05-01-2025

  • Price Drop
    • 27,144 miles
    • 1 accident, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Silver Star Motors (196 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Long Island City, NY / 196 miles away from Syracuse, NY

    CALL FOR MORE INFORMATION! CLEAN CARFAX!, BUY WITH TOTAL CONFIDENCE!, Mercedes-Benz Certified Pre-Owned, ORIGINAL MSRP OVER $67K!!!, 4MATIC®, Active B...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB3NB049385
    Stock: U19591A
    Certified Pre-Owned: Yes
    Listed since: 05-23-2025

    • 18,323 miles
    • No accidents, 3 owners, personal use only
    • 23 City / 30 Hwy MPG
    • Marty’s GMC (287 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Kingston, MA / 287 miles away from Syracuse, NY

    *EXCELLENT Service History!*, 4-Wheel Disc Brakes, Alloy wheels, Android Auto®, Apple CarPlay®, Apple CarPlay®/Android Auto®, Auto-dimming door mirror...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB0NB084677
    Stock: 225346A
    Certified Pre-Owned: No
    Listed since: 04-23-2025

  • Price Drop
    $26,799
    fair price
    $400 below market
    • 51,144 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Carget Motors (311 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Woodbridge, VA / 311 miles away from Syracuse, NY

    The 2020 Mercedes-Benz E 350 is a sophisticated luxury sedan that exemplifies elegance, performance, and advanced technology. With its sleek design, r...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EBXLA828463
    Stock: 828463
    Certified Pre-Owned: No
    Listed since: 05-26-2025

  • New Listing
    $24,866
    fair price
    $318 below market
    • 69,618 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Exclusive Motor Cars (256 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Randallstown, MD / 256 miles away from Syracuse, NY

    This 2020 Black Mercedes-Benz E 350 AWD 4MATIC® is well equipped and includes these features and benefits:. 4MATIC® Clean CARFAX. 23/32 City/Highway...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: WDDZF8EB7LA701329
    Stock: A701329
    Certified Pre-Owned: No
    Listed since: 05-29-2025

  • $22,163
    fair price
    $109 above market
    • 91,123 miles
    • No accidents, 3 owners, personal use
    • 6cyl automatic
    • Carget Motors (311 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Woodbridge, VA / 311 miles away from Syracuse, NY

    Here it is! Hurry and take advantage now! This Mercedes-Benz won t be on the lot long! A great car and a great value! A turbocharger further enhances ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: W1K1J6JB6LF132532
    Stock: 132532
    Certified Pre-Owned: No
    Listed since: 10-11-2024

  • $64,000
    fair price
    $1,531 above market
    • 28,331 miles
    • No accidents, 1 owner, personal use only
    • 6cyl automatic
    • Mercedes-Benz Of Massapequa (216 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 216 miles away from Syracuse, NY

    Certified. CARFAX One-Owner. Clean CARFAX.2022 Mercedes-Benz E-Class E 53 AMG® 4MATIC® I6 4MATIC® 9-Speed Automatic Obsidian Black Metalli...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: W1K1J6BB6NF180761
    Stock: NF180761T
    Certified Pre-Owned: Yes
    Listed since: 05-19-2025

  • Price Drop
    • 42,557 miles
    • No accidents, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • Silver Star Motors (196 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Long Island City, NY / 196 miles away from Syracuse, NY

    CALL FOR MORE INFORMATION! Mercedes-Benz Certified Pre-Owned, 4MATIC®, 12.3" Digital Instrument Cluster, Active Parking Assist, AMG® Body Styling, Hea...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: WDDZF8EB0LA728078
    Stock: U19582
    Certified Pre-Owned: Yes
    Listed since: 05-18-2025

  • $26,795
    fair price
    $509 above market
    • 61,806 miles
    • No accidents, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • G Motors Old Bridge (204 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Old Bridge, NJ / 204 miles away from Syracuse, NY

    2020 Mercedes-Benz E-Class E 350 4MATIC Sedan 4DLooking for luxury and performance? The 2020 Mercedes-Benz E-Class E 350 4MATIC Sedan delivers both in...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EBXLA845375
    Stock: OL845375
    Certified Pre-Owned: No

    • 11,767 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz Manhattan (193 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in New York, NY / 193 miles away from Syracuse, NY

    Certified. Clean CARFAX. Odometer is 17648 miles below market average! 21/29 City/Highway MPGMercedes-Benz Manhattan features a 330,000 square foot st...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB9NB032591
    Stock: 709564
    Certified Pre-Owned: Yes
    Listed since: 02-26-2025

  • Price Drop
    $38,467
    fair price
    $841 above market
    • 57,125 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • Lynnes Nissan City (186 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bloomfield, NJ / 186 miles away from Syracuse, NY

    This 2022 Mercedes-Benz E-Class has passed the Lynnes comprehensive 172 point inspection with flying colors. Our ASE certified technicians have inspec...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/30 Highway)

    Listing Information:

    VIN: W1K1J5KB2NF175115
    Stock: E8187P
    Certified Pre-Owned: No
    Listed since: 02-28-2025

    • 22,225 miles
    • Insurance loss reported, 2 owners, personal use
    • 6cyl automatic
    • Automotive Avenues (222 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wall, NJ / 222 miles away from Syracuse, NY

    Just arrived is this technologically advanced, NONSMOKER 2022 Mercedes-Benz E 450 coupe! ''The Mercedes-Benz E-Class gets a refresh for 2021, helping ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JB7NF173409
    Stock: 53342
    Certified Pre-Owned: No
    Listed since: 04-08-2025

    • 21,624 miles
    • Frame damage reported, 1 owner, corporate fleet vehicle
    • 23 City / 30 Hwy MPG
    • Automotive Avenues (222 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Wall, NJ / 222 miles away from Syracuse, NY

    Just arrived is this technologically advanced, ONE-OWNER, OFF-LEASE, NONSMOKER, ALL-WHEEL DRIVE 2022 Mercedes-Benz E 450 4MATIC sedan! ''The Mercedes-...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB4NB012591
    Stock: 53724
    Certified Pre-Owned: No
    Listed since: 05-21-2025

  • New Listing
    Photos not available
    • 37,818 miles
    • 1 accident, 1 owner, personal use only
    • 7 Seats, 21 City / 28 Hwy MPG
    • Douglas INFINITI (185 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Summit, NJ / 185 miles away from Syracuse, NY

    **** LOADED, AWD, DRIVER ASSISTANCE PKG, EXTERIOR LIGHTING PKG, WARMTH & COMFORT PKG, SUN PROTECTION PKG, ACOUSTIC COMFORT PKG, PREMIUM PKG, PANO/ROOF...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: W1KZH6AB7NB028575
    Stock: 39688U
    Certified Pre-Owned: No
    Listed since: 05-28-2025

Showing 106 - 126 out of 2,210 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.5 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (73%)
  • 4 star
    (21%)
  • 3 star
    (0%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2022 Mercedes-Benz E-Class in Syracuse, NY Values

Estimated values
2022 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$29,751$32,589$35,569
Clean$29,233$31,954$34,802
Average$28,370$30,895$33,524
Rough$27,248$29,519$31,862

The average list price of a used 2022 Mercedes-Benz E-Class in Syracuse, New York is $38,457. The average mileage on a used Mercedes-Benz E-Class 2022 for sale in Syracuse, New York is 40,994. Based on the average mileage of 40,994 for used 2022 Mercedes-Benz E-Class for sale in Syracuse, NY and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2022 in Syracuse, New York to be $28,370.

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