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1,958 listings
  • Price Drop
    $43,590
    fair price
    $1,545 above market
    • 52,940 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 30 Hwy MPG
    • Carvana - Cincinnati (405 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cincinnati, OH / 405 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB0NB022602
    Stock: 2003619004
    Certified Pre-Owned: No
    Listed since: 06-03-2025

    • 4,338 miles
    • No accidents, 1 owner, personal use only
    • 21 City / 29 Hwy MPG
    • Carvana - Dallas (477 mi away)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 477 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB8NB087588
    Stock: 2003835915
    Certified Pre-Owned: No
    Listed since: 07-02-2025

  • $34,920
    fair price
    $298 below market
    • 46,192 miles
    • No accidents, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • ALM Kennesaw (235 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Kennesaw, GA / 235 miles away from Tupelo, MS

    HEATED SEATS..MEMORY SEATS..NAVIGATION..BLIND SPOT MONITOR..BACK UP CAMERA..POWER SEATS..SMART DEVICE INTEGRATION..BLUETOOTH..KEYLESS ENTRY..FULLY LOA...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7NB076834
    Stock: NB076834
    Certified Pre-Owned: No
    Listed since: 06-09-2025

  • $40,500
    fair price
    $902 above market
    • 23,800 miles
    • No accidents, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Auto Collection of Murfreesboro (168 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Murfreesboro, TN / 168 miles away from Tupelo, MS

    2022 Mercedes-Benz E 350 PREMIUM PKG LITE, WARMTH & COMFORT PKGOptional Equipment & Packages<ul data-end=...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB8NB081556
    Stock: 081556
    Certified Pre-Owned: No
    Listed since: 05-19-2025

    • 14,264 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Mercedes-Benz of Plano (476 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Plano, TX / 476 miles away from Tupelo, MS

    2022 Mercedes-Benz E-Class E 350 ***CERTIFIED***, E 350, 4D Sedan, I4, 9-Speed Automatic, RWD, Black, Black w/MB-Tex Upholstery, AMG® Line Exterior, B...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB4NB028336
    Stock: BNB028336
    Certified Pre-Owned: Yes
    Listed since: 06-18-2025

  • $46,490
    fair price
    $650 above market
    • 20,163 miles
    • No accidents, 2 owners, personal use
    • 6cyl automatic
    • Unlimited Motors Westfield (421 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Westfield, IN / 421 miles away from Tupelo, MS

    Navigation, Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Vented Seats, Blind Spot, E-Class E 450, 2D Coupe, 3.0L I6 Turbo, 9-...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JB6NF185003
    Stock: STK185003
    Certified Pre-Owned: No
    Listed since: 08-21-2024

    • 14,998 miles
    • No accidents, 1 owner, personal use
    • 24 City / 33 Hwy MPG
    • Jack Ingram Motors (194 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Montgomery, AL / 194 miles away from Tupelo, MS

    Experience modern sophistication and cutting-edge innovation in this Certified Pre-Owned 2024 Mercedes-Benz E 350 4MATIC®, presented in a sleek White ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB7RA006139
    Stock: M6562A
    Certified Pre-Owned: Yes
    Listed since: 04-02-2025

    • 30,765 miles
    • No accidents, 2 owners, personal use only
    • 6cyl automatic
    • Autos of Dallas - Plano (474 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Plano, TX / 474 miles away from Tupelo, MS

    AMG Sport Pkg, Night Pkg, Premium 1 Pkg, Parking Assistance Pkg, Navigation, Surround View Camera System, Climate Seats, Parktronic, 20" AMG Wheels, K...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1K5JB3NF181133
    Stock: 181133
    Certified Pre-Owned: No
    Listed since: 05-20-2025

  • Price Drop
    • 1,846 miles
    • Lemon reported, 1 owner, personal use only
    • 24 City / 33 Hwy MPG
    • ALM Gwinnett (261 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Duluth, GA / 261 miles away from Tupelo, MS

    LEATHER PACKAGE - DB1..DIGITAL LIGHT PACKAGE - DA4..TONKA BROWN/BLACK, NAPPA LEATHER UPHOLSTERY..NEVA GREY/BLACK, NAPPA LEATHER UPHOLSTERY..WHEELS: 20...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HBXRA025056
    Stock: RA025056
    Certified Pre-Owned: No
    Listed since: 06-11-2025

  • Price Drop
    $39,991
    fair price
    $1,401 above market
    • 33,779 miles
    • No accidents, 2 owners, personal use only
    • 23 City / 31 Hwy MPG
    • Mercedes-Benz of Orange Park (493 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 493 miles away from Tupelo, MS

    Recent Arrival! ** MERCEDES-BENZ CERTIFIED PRE-OWNED, ** UNLIMITED MILES LIMITED FACTORY WARRANTY, ** LOCAL TRADE, ** AMG STYLING, AMG® Line Exterior,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB0NB045828
    Stock: PR6021A
    Certified Pre-Owned: Yes
    Listed since: 06-30-2025

    • 34,765 miles
    • No accidents, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Go Luxury Auto Group (480 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 480 miles away from Tupelo, MS

    Priced below KBB Fair Purchase Price!CARFAX One-Owner.2022 Mercedes-Benz E-Class E 350 RWD 4D Sedan I4 Blue 9-Speed Automatic*Bluetooth / Hands ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXNB045044
    Stock: A45044
    Certified Pre-Owned: No
    Listed since: 05-08-2025

    • 53,405 miles
    • 1 accident, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Waxahachie Dodge Chrysler Jeep Ram (489 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Waxahachie, TX / 489 miles away from Tupelo, MS

    Gray 2022 Mercedes-Benz E-Class E 350 I4 RWD 9-Speed Automatic2 Years Free Oil Changes. Recent Arrival! 23/31 City/Highway MPG

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB1NB076649
    Stock: PD4261
    Certified Pre-Owned: No
    Listed since: 05-13-2025

  • Price Drop
    • 20,164 miles
    • Lemon reported, 1 owner, personal use only
    • 21 City / 29 Hwy MPG
    • ALM Marietta (240 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Marietta, GA / 240 miles away from Tupelo, MS

    $92K ORIGINAL MSRP !!!..AMG NIGHT PACKAGE..DRIVER ASSISTANCE PACKAGE..WARMTH & COMFORT PACKAGE..AIR BALANCE PACKAGE..PREMIUM SOUND SYSTEM..MASSAGING S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB3NB090933
    Stock: NB090933
    Certified Pre-Owned: No
    Listed since: 04-03-2025

    • 42,119 miles
    • No accidents, 1 owner, personal use only
    • 6cyl automatic
    • Autos of Dallas - Plano (474 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Plano, TX / 474 miles away from Tupelo, MS

    AMG Sport Pkg, Premium 1 Pkg, Parking Assistance Pkg, Navigation, Surround View Camera System, Panoramic Roof, Climate Seats, Parktronic, 20" AMG Whee...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JBXNF185411
    Stock: 185411
    Certified Pre-Owned: No
    Listed since: 04-18-2025

  • Price Drop
    • 22,864 miles
    • Insurance loss reported, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Alm Mall Of Georgia (267 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Buford, GA / 267 miles away from Tupelo, MS

    $89K ORIGINAL MSRP !!!..DRIVER ASSISTANCE PACKAGE - DA2..AMG NIGHT PACKAGE - DC1..EXTERIOR LIGHTING PACKAGE - DA4..AMG EXTERIOR CARBON FIBER PACKAGE I...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB5NB032399
    Stock: NB032399
    Certified Pre-Owned: No
    Listed since: 03-13-2025

    • 74,740 miles
    • No accidents, 1 owner, personal use only
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of Louisville (328 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Louisville, KY / 328 miles away from Tupelo, MS

    Mercedes-Benz Certified Pre-Owned Details:* Vehicle History* 165+ Point Inspection* Limited Warranty: 12 Month/Unlimited Mile beginning after new car ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB2NB073466
    Stock: 373085A
    Certified Pre-Owned: Yes
    Listed since: 06-30-2025

    • 58,241 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Driveline Motorcars (478 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Farmers Branch, TX / 478 miles away from Tupelo, MS

    CARFAX One-Owner. Clean CARFAX.Black 2022 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic I44-Wheel Disc Brakes, 8 Speakers, ABS brakes, Air Con...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB0NB026261
    Stock: NB026261
    Certified Pre-Owned: No
    Listed since: 06-17-2025

  • New Listing
    • 68,127 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 21 City / 29 Hwy MPG
    • IMD MOTORS (482 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 482 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB3NB054689
    Stock: NB054689
    Certified Pre-Owned: No
    Listed since: 07-04-2025

    • 45,058 miles
    • No accidents, 2 owners, personal use only
    • 23 City / 31 Hwy MPG
    • Autos of Dallas - Plano (474 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Plano, TX / 474 miles away from Tupelo, MS

    AMG Sport Pkg, Night Pkg, Premium 1 Pkg, Navigation, Surround View System, Sun Roof, Heated Seats, 19" AMG 10-Spoke Wheels, Blind Spot Monitor, Keyles...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: Yes

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2NB086025
    Stock: 086025
    Certified Pre-Owned: No
    Listed since: 05-15-2025

  • $38,921
    fair price
    $1,391 above market
    • 56,270 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Hyundai of Cool Springs (157 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Franklin, TN / 157 miles away from Tupelo, MS

    We are thrilled to offer this 2022 Mercedes-Benz E-Class E 350 in Gray with Titanium Gray/Black Leatherette Seat Trim. For more details on this E-Clas...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7NB091320
    Stock: G047051B
    Certified Pre-Owned: No
    Listed since: 06-24-2025

    • 1,000 miles
    • No accidents, personal use only
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Centerville (447 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Centerville, OH / 447 miles away from Tupelo, MS

    2024 Mercedes-Benz E 350 4MATICExterior: Verde Silver MetallicInterior: Black Nappa LeatherWheels: 20"" AMG Multispoke Wheels with Black AccentsComfor...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HBXRA058123
    Stock: D6051
    Certified Pre-Owned: No
    Listed since: 05-28-2024

Showing 64 - 84 out of 1,958 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.2 out of 5 stars31 Reviews
Write a vehicle reviewSee all 31 reviews
  • 5 star
    (65%)
  • 4 star
    (16%)
  • 3 star
    (6%)
  • 2 star
    (3%)
  • 1 star
    (10%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2022 Mercedes-Benz E-Class in Tupelo, MS Values

Estimated values
2022 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$35,862$38,338$40,934
Clean$35,238$37,590$40,051
Average$34,198$36,345$38,580
Rough$32,845$34,725$36,668

The average list price of a used 2022 Mercedes-Benz E-Class in Tupelo, Mississippi is $45,378. The average mileage on a used Mercedes-Benz E-Class 2022 for sale in Tupelo, Mississippi is 34,278. Based on the average mileage of 34,278 for used 2022 Mercedes-Benz E-Class for sale in Tupelo, MS and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2022 in Tupelo, Mississippi to be $34,198.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.