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229 listings
- Price Drop$38,000great price$3,067 below market
- 38,900 miles
- No accidents, 2 owners, personal use only
- 19 City / 26 Hwy MPG
- Patriot Acura (6 mi away)
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Located in Scarborough, ME / 6 miles away from South Portland, ME
No matter what your automotive needs may be, you'll find answers here at Patriot Acura. This 2022 Lexus IS IS 350 F SPORT has a beautiful Infrared ext...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24N5023696
Stock: 22P3696
Certified Pre-Owned: No
Listed since: 03-04-2025 - New Listing$38,998great price$2,650 below market
- 47,921 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Herb Chambers Lexus (116 mi away)
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Located in Sharon, MA / 116 miles away from South Portland, ME
INSPECTION COMPLETED Every Herb Chambers Certified pre-owned vehicle receives a complete multi-point inspection by factory trained technicians who ins...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XN5025839
Stock: H10811A
Certified Pre-Owned: Yes
Listed since: 03-18-2025 - Price Drop$40,853good price$1,330 below market
- 14,937 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Lia Chrysler Jeep Dodge Ram Northampton (151 mi away)
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Located in Northampton, MA / 151 miles away from South Portland, ME
White 2022 Lexus IS 350 F SPORT 3.5L V6 DOHC Dual VVT-i 24V 6-Speed Automatic AWDOne Owner - Clean CarFax *, Power Moonroof / Sunrof *, ABS brakes, Ap...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25N5026848
Stock: N5026848TL
Certified Pre-Owned: No
Listed since: 03-22-2025 - $42,333fair price$732 below market
- 23,613 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (446 mi away)
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Located in Owings Mills, MD / 446 miles away from South Portland, ME
Certified. CARFAX One-Owner.Ultrasonic Blue Mica 2.0 2022 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Circuit Red w/Bla...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21N5026331
Stock: BL1351
Certified Pre-Owned: Yes
Listed since: 03-07-2025 - Price Drop$40,444fair price$413 below market
- 20,513 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Driveway (261 mi away)
- Home delivery*
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Located in Middletown, NY / 261 miles away from South Portland, ME
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Ste...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5026648
Stock: N5026648T
Certified Pre-Owned: No - $39,990fair price$353 below market
- 24,618 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Honda of Manhasset (265 mi away)
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Located in Manhasset, NY / 265 miles away from South Portland, ME
Titan Motor Group has a wide selection of exceptional pre-owned vehicles to choose from. This Lexus includes: CARGO NET (PPO) POWER TILT Generic Sun/M...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24N5025674
Stock: MU1552T
Certified Pre-Owned: No
Listed since: 04-21-2025 - Price Drop$36,500good price$1,181 below market
- 71,514 miles
- No accidents, 2 owners, corporate fleet vehicle
- 19 City / 26 Hwy MPG
- Toyota of Keene (113 mi away)
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Located in Swanzey, NH / 113 miles away from South Portland, ME
Certified. Clean CARFAX. 2022 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Circuit Red Artificial Leather.19/26 City...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21N5026426
Stock: 25BP036
Certified Pre-Owned: No
Listed since: 02-17-2025 - $39,995good price$1,745 below market
- 65,293 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Ray Catena Lexus of Freehold (312 mi away)
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Located in Freehold, NJ / 312 miles away from South Portland, ME
Certified. Ultrasonic Blue Mica 2.0 2022 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V ALL AUTOMOBILE BUYING EXPERIENCES ARE ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5024365
Stock: Z9595
Certified Pre-Owned: Yes
Listed since: 04-21-2025 - 20,922 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Wilkie Lexus (361 mi away)
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Located in Haverford, PA / 361 miles away from South Portland, ME
Caviar 2022 Lexus IS 350 F SPORT AWD, White w/Black w/F SPORT NuLuxe Seat Trim, Power Tilt & Slide Moonroof. L/Certified Details:* Warranty Deductible...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25N5025344
Stock: 250772A
Certified Pre-Owned: Yes
Listed since: 04-08-2025- 25,617 miles
- No accidents, 1 owner, personal use
- 20 City / 28 Hwy MPG
- Elite Mitsubishi (274 mi away)
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Located in Jamaica, NY / 274 miles away from South Portland, ME
Advertised price does not include tax, title, license inspection, finance charges, lender fees (if applicable) or dealer prep charges. To take advanta...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26N5056817
Stock: 6817
Certified Pre-Owned: No
Listed since: 04-28-2025- 27,470 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Car Quest (267 mi away)
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Located in Great Neck, NY / 267 miles away from South Portland, ME
All pricing and details on this website are believed to be accurate, but we do not warrant or guarantee such accuracy. Please call or email us for com...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22N5026189
Stock: C5021-215
Certified Pre-Owned: No
Listed since: 04-11-2025- 27,620 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Car Quest (267 mi away)
Close
Located in Great Neck, NY / 267 miles away from South Portland, ME
All pricing and details on this website are believed to be accurate, but we do not warrant or guarantee such accuracy. Please call or email us for com...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XN5027249
Stock: C4911-215
Certified Pre-Owned: No
Listed since: 02-26-2025- $45,000great price$5,701 below market
- 12,401 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Lexus of Wilmington (384 mi away)
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Located in Wilmington, DE / 384 miles away from South Portland, ME
**1 OWNER****L-CERTIFIED****NAVIGATION SYSTEM****MARK LEVINSON AUDIO****POWER MOONROOF****MEMORY PACKAGE**L/Certified Details: * Vehicle His...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26P5031396
Stock: RU031396
Certified Pre-Owned: Yes
Listed since: 04-30-2025 - New Listing
- 23,904 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Ray Catena Lexus of Freehold (312 mi away)
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Located in Freehold, NJ / 312 miles away from South Portland, ME
Caviar 2022 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V ALL AUTOMOBILE BUYING EXPERIENCES ARE NOT CREATED EQUAL,STOP IN AND...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5023698
Stock: F251370A
Certified Pre-Owned: No
Listed since: 05-03-2025 - New Listing
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Located in Laurel, MD / 462 miles away from South Portland, ME
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29N5023936
Stock: 26866929
Certified Pre-Owned: No - $42,850great price$3,414 below market
- 15,392 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Lexus of Towson (440 mi away)
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Located in Towson, MD / 440 miles away from South Portland, ME
Certified. CARFAX One-Owner. 2023 Lexus IS 350 F SPORT Atomic Silver AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V---L/CERTIFIED---, ---UNLIMITED ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25P5032815
Stock: BT1584
Certified Pre-Owned: Yes
Listed since: 04-10-2025 - $42,878great price$2,730 below market
- 13,842 miles
- No accidents, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Lexus of Queens (274 mi away)
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Located in Long Island City, NY / 274 miles away from South Portland, ME
Welcome to Lexus of Queens, where luxury meets exceptional service. We pride ourselves on delivering an unparalleled automotive purchasing experience....
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27P5027308
Stock: QX14984
Certified Pre-Owned: No
Listed since: 03-31-2025 - $45,995great price$2,726 below market
- 6,776 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Platinum Auto Sales of Arlington Virginia (484 mi away)
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Located in Arlington, VA / 484 miles away from South Portland, ME
Non-smoker owner, Vehicle Runs Well, Smooth ride, All records in possession, Regularly maintained, Lots of storage, Arctic cold a/c, No pets, Seats as...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27P5032301
Stock: JTHGZ1E27P5032301
Certified Pre-Owned: No - $34,995great price$2,402 below market
- 42,921 miles
- 1 accident, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (284 mi away)
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Located in Brooklyn, NY / 284 miles away from South Portland, ME
Looking for a quality used car? Here's why Lexus of Brooklyn is your top choice: Quality Assurance: Rigorous inspections ensure top-notch quality and ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24M5018819
Stock: BX23175
Certified Pre-Owned: Yes
Listed since: 03-25-2025 - $44,577good price$2,442 below market
- 24,404 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (446 mi away)
Close
Located in Owings Mills, MD / 446 miles away from South Portland, ME
Certified. CARFAX One-Owner.Cloudburst Gray 2023 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Black w/Satin Chrome Trim ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21P5031824
Stock: L2162A
Certified Pre-Owned: Yes
Listed since: 04-04-2025 - $46,484good price$1,966 below market
- 8,274 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Ourisman Honda (479 mi away)
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Located in Bethesda, MD / 479 miles away from South Portland, ME
2023 Lexus IS 350 F SPORT Silver clean carfax, AWD 4WD ALL WHEEL DRIVE FOUR WHEEL DRIVE 4X4, BACK UP CAMERA REAR VIEW CAMERA, LEATHER, HEATED SEATS, S...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XP5028579
Stock: 156382A
Certified Pre-Owned: No
Listed since: 04-19-2025
Showing 1 - 21 out of 229 listings
Consumer Reviews for the Lexus IS 350
Read recent reviews for the Lexus IS 350
10's across the board...
DaddyG, 01/23/2022
2022 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A)
First I must say that I am a huge Lexus fan after having owned multiple Mercedes and BMW's. I have owned 2 GX460's and 2 ES350's and a first generation IS300. This time I wanted something sportier. I have probably owned 50+ cars in my lifetime and this is hands down my favorite ever. Its sporty, comfortable and a huge value for the price compared to the german brands. I have Atomic … Silver over red and I get at least a couple compliments every day on what a beautiful car I have.
Over all of my ownerships I have had ZERO problems with any of my Lexus's unlike my experience with both BMW and Mercedes which seemed to always have something wrong with them. On top of that when it comes time to trade them in they are still worth something.
Not sure what the "experts" are saying about the acceleration on the IS. Mine is a rocket and that exhaust note is addicting. Plus I love the fact that I am driving something that is unique to the masses. If you get one, get the FSport with the Dynamic Handling Package. For 50k you have a fully loaded sports sedan that will give you constant joy!
Used 2022 Lexus IS 350 in South Portland, ME Values
Estimated values
2022 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $35,274 | $37,856 | $40,555 |
| Clean | $34,684 | $37,180 | $39,785 |
| Average | $33,701 | $36,053 | $38,502 |
| Rough | $32,422 | $34,588 | $36,833 |
The average list price of a used 2022 Lexus IS 350 in South Portland, Maine is $41,800. The average mileage on a used Lexus IS 350 2022 for sale in South Portland, Maine is 27,801. Based on the average mileage of 27,801 for used 2022 Lexus IS 350 for sale in South Portland, ME and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2022 in South Portland, Maine to be $33,701.
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