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150 listings
- $39,495good price$2,769 below market
- 19,862 miles
- No accidents, 4 owners, personal use only
- 6cyl automatic
- AutoNation USA St. Louis (250 mi away)
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Located in St Peters, MO / 250 miles away from Des Moines, IA
Navigation PackagePower Tilt & Slide MoonroofIntuitive Park Assist W/Auto BrakingSun/MoonroofPremium Paint (Pj)Navigation SystemDoor Edge Film B...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29N5049506
Stock: N5049506
Certified Pre-Owned: No
Listed since: 02-07-2025 - $42,522fair price$534 below market
- 22,897 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Jay Wolfe Toyota of West County (263 mi away)
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Located in Ballwin, MO / 263 miles away from Des Moines, IA
ONE OWNER// NO ACCIDENTS// DETAILED SERVICE RECORDS// IMMACULATE.intuitive parking assist with auto braking and rear cross-traffic braking // memory ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B20N5054769
Stock: WP9668
Certified Pre-Owned: No
Listed since: 04-30-2025 - 22,772 miles
- No accidents, 2 owners, personal use only
- 6cyl automatic
- Guaranteed Motor Cars - Lake Villa (291 mi away)
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Located in Lake Villa, IL / 291 miles away from Des Moines, IA
IS 350 F SPORT, 4D Sedan, 3.5L V6 DOHC Dual VVT-i 24V, 8-Speed Automatic, RWD, White, White Artificial Leather, Navigation Package w/Mark Levinson Aud...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B24N5050899
Stock: LV293
Certified Pre-Owned: No
Listed since: 04-01-2025- 21,662 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Zeigler Chevrolet Schaumburg (289 mi away)
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Located in Schaumburg, IL / 289 miles away from Des Moines, IA
2022 Lexus IS 350 F SPORT AWD, Black w/Black Metallic w/NuLuxe Seat Trim. SilverAWD, Black w/Black Metallic w/NuLuxe Seat Trim, 10 Speakers, 4-Wheel...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5026567
Stock: P1027
Certified Pre-Owned: No
Listed since: 02-25-2025- New Listing$37,967fair price$93 below market
- 53,000 miles
- 1 accident, 2 owners, personal use only
- 6cyl automatic
- Caldwell Toyota (455 mi away)
- Five Star Dealer
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Located in Conway, AR / 455 miles away from Des Moines, IA
OPEN NOW! TO KEEP YOU SAFE, DIGITAL ONLINE BUYING EXPERIENCE AVAILABLEBUY ONLINE-TEXT-EMAIL-CHAT-PHONEFROM OUR SALES FLOOR TO YOUR DOOR!IT'S THAT EASY...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22N5051436
Stock: 250662A
Certified Pre-Owned: No
Listed since: 05-05-2025 - Price Drop
- 45,709 miles
- No accidents, 2 owners, personal use only
- 6cyl automatic
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Treat yourself to Lexus Certified ownership privileges:161-point inspection by expert Lexus technicians ensures exemplary condition24/7 Roadside As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24N5024346
Stock: PBJ1147
Certified Pre-Owned: Yes
Listed since: 04-16-2025 - Price Drop$44,995great price$7,119 below market
- 18,608 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Lexus of Arlington (292 mi away)
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Located in Arlington Heights, IL / 292 miles away from Des Moines, IA
Certified. 2023 Lexus IS 350 F SPORT Automatic, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Heated Seats, Keyless Entry, KEYLESS STAR...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25P5070694
Stock: AL1151S
Certified Pre-Owned: Yes
Listed since: 04-10-2025 - $45,732fair price$739 below market
- 24,472 miles
- No accidents, 2 owners, personal use only
- 6cyl automatic
- Jim Norton Toyota of Oklahoma City (469 mi away)
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Located in Oklahoma City, OK / 469 miles away from Des Moines, IA
This 2021 Lexus IS IS 350 F SPORT, has a Ultra White exterior and a Flare Red w/Ginsumi interior. Please call us at 405-443-3142 and reference stock n...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22M5040354
Stock: 26664B
Certified Pre-Owned: No
Listed since: 04-29-2025 - Price Drop$42,698fair price$1,214 above market
- 22,663 miles
- No accidents, 1 owner, personal use only
- 6cyl automatic
- Walser Auto Campus (329 mi away)
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Located in Wichita, KS / 329 miles away from Des Moines, IA
2021 Lexus IS 350 F SPORT RWD, located at Lexus of Wichita. Original MSRP $48,780. Atomic Silver with Black Leather interior. This 1 owner IS is equip...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25M5046973
Stock: 54L1099T
Certified Pre-Owned: No
Listed since: 02-22-2025 - New Listing
- 35,272 miles
- No accidents, 2 owners, personal use only
- 6cyl automatic
- Eddy's Toyota of Wichita (332 mi away)
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Located in Wichita, KS / 332 miles away from Des Moines, IA
**CLEAN AutoCheck**, Back-Up Camera, All-Wheel Drive, Navigation, Heated Seats, Ventilated Seats, Leather Seats, Sunroof/Moonroof, Blind Spot Monitor,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23M5020464
Stock: 87835A
Certified Pre-Owned: No
Listed since: 03-28-2025 - New Listing$39,994fair price$2,104 above market
- 49,666 miles
- No accidents, 2 owners, personal use
- 6cyl automatic
- Zeigler Honda of Racine (301 mi away)
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Located in Mount Pleasant, WI / 301 miles away from Des Moines, IA
CLEAN CARFAX!AWD ++, APPLE CARPLAY, ANDROID AUTO, BLIND SPOT MONITOR, REMOTE START, LANE DEPARTURE WARNING, PARKING SENSORS, HEATED STEERING WHEEL,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26M5020667
Stock: P12480
Certified Pre-Owned: No
Listed since: 05-02-2025 - New Listing
- 379 miles
- No accidents, 1 owner, personal use only
- 6cyl automatic
- Carvana - Oklahoma City (472 mi away)
- Home delivery*
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Located in Oklahoma City, OK / 472 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B25P5068759
Stock: 2003618279
Certified Pre-Owned: No
Listed since: 04-09-2025 - 13,328 miles
- No accidents, 1 owner, personal use only
- 6cyl automatic
- Fishers Imports (414 mi away)
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Located in Fishers, IN / 414 miles away from Des Moines, IA
This is One of kind unit with F sport package design with all the right options. This Unit is located at our 9550 E 126th st Location in Fishers Acr...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23P5027784
Stock: I7784
Certified Pre-Owned: No
Listed since: 03-08-2025- Price Drop
- 87,585 miles
- No accidents, 2 owners, corporate fleet vehicle
- 6cyl automatic
- Conklin Salina Chevrolet (286 mi away)
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Located in Salina, KS / 286 miles away from Des Moines, IA
Clean CARFAX. 2021 Lexus IS 350 F SPORT Silver AWD, Black Leather.Drive Forever limited lifetime engine and transmission protection on all eligible ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23M5022988
Stock: SX7479A
Certified Pre-Owned: No
Listed since: 03-10-2025 - 60,144 miles
- No accidents, 3 owners, corporate fleet vehicle
- 6cyl automatic
- City Auto Memphis (486 mi away)
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Located in Memphis, TN / 486 miles away from Des Moines, IA
Vehicle DetailsExperience luxury and performance with this 2021 Lexus IS 350 F Sport, a stunning blend of style and engineering precision. Thi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26M5045671
Stock: 509301
Certified Pre-Owned: No
Listed since: 04-10-2025- $40,964good price$1,002 below market
- 19,987 miles
- No accidents, 1 owner, personal use only
- 6cyl automatic
- Smart Lexus (158 mi away)
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Located in Davenport, IA / 158 miles away from Des Moines, IA
Certified. Ultrasonic Blue Mica 2.0 2022 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V For more info. please call TJ Deere Ma...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5024253
Stock: L3P024253
Certified Pre-Owned: Yes
Listed since: 03-14-2025 - $41,988fair price$924 below market
- 20,969 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Audi Omaha (135 mi away)
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Located in Omaha, NE / 135 miles away from Des Moines, IA
At Audi Omaha, were excited to offer this 2022 Lexus IS 350 F SPORT a perfect combination of aggressive styling, thrilling performance, and cutting-ed...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25N5023710
Stock: AB027712A
Certified Pre-Owned: No
Listed since: 02-27-2025 - Price Drop$40,444fair price$795 below market
- 20,513 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Driveway (In-stock online)
- Home delivery*
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Located in Middletown, NY / 991 miles away from Des Moines, IA
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Ste...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28N5026648
Stock: N5026648T
Certified Pre-Owned: No - New Listing$39,995good price$2,873 below market
- 28,826 miles
- 6cyl automatic
- Goben Cars West (235 mi away)
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Located in Middleton, WI / 235 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B2XN5057324
Stock: 23248
Certified Pre-Owned: No
Listed since: 03-01-2025 - $38,998good price$2,114 below market
- 40,608 miles
- 1 accident, 1 owner, personal use only
- 6cyl automatic
- Driveway (In-stock online)
- Home delivery*
Close
Located in Fresno, CA / 1,432 miles away from Des Moines, IA
CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B20N5049524
Stock: N5049524P
Certified Pre-Owned: No - Price Drop$41,034good price$1,456 below market
- 37,533 miles
- No accidents, 1 owner, personal use
- 6cyl automatic
- Lexus of Fort Wayne (437 mi away)
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Located in Fort Wayne, IN / 437 miles away from Des Moines, IA
2022 Lexus IS 350 F SPORT Gray RWDAt Bob Rohrman Dealerships Our selection is Outstanding. We believe that we truly have a certified preowned vehicle ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B21N5058488
Stock: FL1501P
Certified Pre-Owned: Yes
Listed since: 03-13-2025
Showing 1 - 21 out of 150 listings
Consumer Reviews for the Lexus IS 350
Read recent reviews for the Lexus IS 350
10's across the board...
DaddyG, 01/23/2022
2022 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A)
First I must say that I am a huge Lexus fan after having owned multiple Mercedes and BMW's. I have owned 2 GX460's and 2 ES350's and a first generation IS300. This time I wanted something sportier. I have probably owned 50+ cars in my lifetime and this is hands down my favorite ever. Its sporty, comfortable and a huge value for the price compared to the german brands. I have Atomic … Silver over red and I get at least a couple compliments every day on what a beautiful car I have.
Over all of my ownerships I have had ZERO problems with any of my Lexus's unlike my experience with both BMW and Mercedes which seemed to always have something wrong with them. On top of that when it comes time to trade them in they are still worth something.
Not sure what the "experts" are saying about the acceleration on the IS. Mine is a rocket and that exhaust note is addicting. Plus I love the fact that I am driving something that is unique to the masses. If you get one, get the FSport with the Dynamic Handling Package. For 50k you have a fully loaded sports sedan that will give you constant joy!
Used 2022 Lexus IS 350 in Des Moines, IA Values
Estimated values
2022 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,170 | $35,048 | $37,011 |
| Clean | $32,615 | $34,422 | $36,308 |
| Average | $31,691 | $33,379 | $35,137 |
| Rough | $30,488 | $32,023 | $33,614 |
The average list price of a used 2022 Lexus IS 350 in Des Moines, Iowa is $41,802. The average mileage on a used Lexus IS 350 2022 for sale in Des Moines, Iowa is 31,736. Based on the average mileage of 31,736 for used 2022 Lexus IS 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2022 in Des Moines, Iowa to be $31,691.
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