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1,253 listings
  • Price Drop
    $30,099
    great price
    $7,054 below market
    • 69,730 miles
    • No accidents, 1 owner, personal use
    • 23 City / 30 Hwy MPG
    • Hollywood Kia (88 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Hollywood, FL / 88 miles away from Port Saint Lucie, FL

    WOW! Check out this 2021 Mercedes-Benz E-Class in Polar White!, Imagine yourself in this beauty!, Remaining Factory Warranty, SHE PASSED THE 165 POINT...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB7MA949245
    Stock: A949245
    Certified Pre-Owned: No
    Listed since: 03-27-2025

  • $24,918
    great price
    $4,330 below market
    • 58,011 miles
    • 2 accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Carlux (82 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fort Lauderdale, FL / 82 miles away from Port Saint Lucie, FL

    White 2021 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic I422/31 City/Highway MPGAwards:* Motor Trend Automobiles of the year

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA945821
    Stock: LU1367
    Certified Pre-Owned: No
    Listed since: 03-31-2025

  • $32,873
    great price
    $3,459 below market
    • 35,411 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Mercedes-Benz of Delray (59 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Delray Beach, FL / 59 miles away from Port Saint Lucie, FL

    The following items have been reconditioned on this vehicle: new pair of tires! Premium PackageDriver Assistance PackageSun/MoonroofNavigation S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EBXMA979613
    Stock: MA979613
    Certified Pre-Owned: Yes
    Listed since: 03-31-2025

  • New Listing
    $34,598
    great price
    $4,589 below market
    • 26,771 miles
    • 1 accident, 2 owners, personal use only
    • 22 City / 30 Hwy MPG
    • Mercedes-Benz of Coconut Creek (68 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Coconut Creek, FL / 68 miles away from Port Saint Lucie, FL

    The following items have been reconditioned on this vehicle: all new tires! Premium PackageDriver Assistance PackageAcoustic Comfort PackageHead...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB7MA969914
    Stock: MA969914
    Certified Pre-Owned: Yes
    Listed since: 04-11-2025

  • $29,000
    great price
    $3,898 below market
    • 35,039 miles
    • 1 accident, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Brickell Honda (104 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Miami, FL / 104 miles away from Port Saint Lucie, FL

    🚗✨ Experience the sophistication and performance of this one-owner 2021 Mercedes-Benz E-Class E 350, showcased in elegant Lunar Blue Metallic with a ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MA950883
    Stock: HA10467
    Certified Pre-Owned: No
    Listed since: 03-14-2025

  • $28,995
    great price
    $2,906 below market
    • 59,914 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 22 City / 31 Hwy MPG
    • Gulf Coast Auto Brokers of Sarasota (129 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 129 miles away from Port Saint Lucie, FL

    Thank you for visiting another one of Gulf Coast Auto Brokers Inc's online listings! Please continue for more information on this 2021 Mercedes-Benz E...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MB002459
    Stock: 2459
    Certified Pre-Owned: No
    Listed since: 02-19-2025

  • $31,600
    good price
    $1,210 below market
    • 33,407 miles
    • No accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • North Fort Lauderdale Subaru (74 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fort Lauderdale, FL / 74 miles away from Port Saint Lucie, FL

    Subaru of North Fort Lauderdale is proud to offer this Beautiful 2021 Mercedes-Benz E-Class. This E 350 E-Class is beautifully finished in Obsidian Bl...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA965485
    Stock: S12219A
    Certified Pre-Owned: No
    Listed since: 03-30-2025

  • Price Drop
    $35,577
    good price
    $940 below market
    • 26,095 miles
    • No accidents, 2 owners, personal use only
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Tampa (139 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 139 miles away from Port Saint Lucie, FL

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA933359
    Stock: CMT250871A
    Certified Pre-Owned: Yes
    Listed since: 03-29-2025

  • Price Drop
    • 64,547 miles
    • No accidents, 1 owner, personal use only
    • 7 Seats, 22 City / 28 Hwy MPG
    • Mercedes-Benz of Delray (59 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Delray Beach, FL / 59 miles away from Port Saint Lucie, FL

    The following items have been reconditioned on this vehicle: new pair of tires! Premium PackagePanorama SunroofGraphite Grey MetallicPanoramic R...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (22 City/28 Highway)

    Listing Information:

    VIN: W1KZH6AB6MA955328
    Stock: MA955328
    Certified Pre-Owned: Yes
    Listed since: 03-26-2025

  • Price Drop
    $35,189
    good price
    $2,363 below market
    • 20,596 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Gravity Autos Jacksonville (223 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 223 miles away from Port Saint Lucie, FL

    LOADED E 350! INCLUDES NIGHT PACKAGE, PREMIUM PACKAGE, AMG LINE EXTERIOR, BLIND SPOT ASSIST, HEATED FRONT SEATS, 19" X 8.0" AMG TWIN 5-SPOKE W/BLACK A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB4MB002091
    Stock: 002091
    Certified Pre-Owned: No
    Listed since: 02-06-2025

  • Price Drop
    $32,995
    fair price
    $503 below market
    • 38,900 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Miami (92 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Miami, FL / 92 miles away from Port Saint Lucie, FL

    Premium PackageAmg ® Line ExteriorSun/MoonroofWheels: 19" X 8.0" Amg ® 10-SpokeNavigation SystemAugmented Video For NavigationKeyless St...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MA959471
    Stock: MA959471
    Certified Pre-Owned: Yes
    Listed since: 04-07-2025

  • $46,498
    fair price
    $785 below market
    • 47,350 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 29 Hwy MPG
    • Lexus of Tampa Bay (140 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 140 miles away from Port Saint Lucie, FL

    Black; Nappa Leather UpholsteryMojave Silver MetallicSun/MoonroofLeather SeatsNavigation SystemKeyless StartRear SpoilerThis vehicle includes...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB2MA923982
    Stock: MA923982
    Certified Pre-Owned: No
    Listed since: 04-07-2025

  • Price Drop
    $26,887
    good price
    $2,033 below market
    • 58,796 miles
    • 1 accident, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Gravity Autos Jacksonville (223 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 223 miles away from Port Saint Lucie, FL

    LOADED E 350! INCLUDES PREMIUM PACKAGE, AMG LINE EXTERIOR, NAPPA LEATHER STEERING WHEEL, MB-TEX UPHOLSTERY, HEATED FRONT SEATS, BLIND SPOT ASSIST, LED...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA964415
    Stock: 964415
    Certified Pre-Owned: No
    Listed since: 02-06-2025

  • New Listing
    Stock photo**
    $37,048
    fair price
    $551 below market
    • 20,038 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Tampa (139 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 139 miles away from Port Saint Lucie, FL

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MA970034
    Stock: CMTP211397
    Certified Pre-Owned: Yes
    Listed since: 04-30-2025

  • Price Drop
    $31,998
    fair price
    $482 below market
    • 30,559 miles
    • 1 accident, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Lexus of Pembroke Pines (86 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pembroke Pines, FL / 86 miles away from Port Saint Lucie, FL

    2021 Mercedes-Benz E-Class E 350 Black !!!*** HURRY ***!!!, *!*!*! DON'T MISS OUT !*!*!*, ** BEST COLOR COMBINATION **, 4-Way Power Lumbar Support, 4-...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7MA963600
    Stock: 25193903
    Certified Pre-Owned: No
    Listed since: 03-17-2025

  • Price Drop
    $27,381
    good price
    $1,597 below market
    • 81,372 miles
    • 1 accident, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • Gainesville Chrysler Dodge Jeep Ram (205 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Gainesville, FL / 205 miles away from Port Saint Lucie, FL

    CARFAX One-Owner. Black 2021 Mercedes-Benz E-Class E 350 4MATIC® I4 9-Speed Automatic 4MATIC® 4-Way Power Lumbar Support, Active Parking Assist, Augme...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB9MA895489
    Stock: 24X157B
    Certified Pre-Owned: No
    Listed since: 02-06-2025

  • Price Drop
    • 5,168 miles
    • Insurance loss reported, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • ALM Hyundai Athens (496 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Athens, GA / 496 miles away from Port Saint Lucie, FL

    MEMORY PKG..BLIND SPOT..NAVIGATION..HEATED SEATS..MOONROOF..BACKUP CAMERA..BRAKE ASSIST..KEYLESS ENTRY..BLUETOOTH..**VEHICLE IS A MANUFACTURER BUYBACK...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB5MA914850
    Stock: MA914850
    Certified Pre-Owned: No
    Listed since: 12-27-2024

  • Price Drop
    $39,190
    fair price
    $1,147 below market
    • 39,775 miles
    • 1 accident, 2 owners, personal use
    • 6cyl automatic
    • Gravity Autos Jacksonville (223 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 223 miles away from Port Saint Lucie, FL

    $6K+ IN OPTIONS! AMG LINE PACKAGE, NIGHT PACKAGE, EXTERIOR LIGHTING PACKAGE, VENTILATED FRONT SEATS, 19'' AMG TWIN 5-SPOKE WHEELS W/BLACK ACCENT, WHEE...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1K1J5KB9MF166703
    Stock: 166703
    Certified Pre-Owned: No
    Listed since: 02-28-2025

  • Price Drop
    • 15,814 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Pompano (71 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pompano Beach, FL / 71 miles away from Port Saint Lucie, FL

    Premium PackageSun/MoonroofNavigation SystemKeyless StartBlack HeadlinerBlack; Mb-Tex UpholsteryBlind Spot AssistHeated Front SeatsNappa Leath...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB3MA940850
    Stock: MA940850
    Certified Pre-Owned: No
    Listed since: 03-15-2025

  • Photos not available
    $53,955
    good price
    $1,097 below market
    • 35,541 miles
    • 1 accident, 1 owner, personal use
    • 6cyl automatic
    • Mercedes-Benz of Tampa (139 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 139 miles away from Port Saint Lucie, FL

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: W1K1J6BB0MF165297
    Stock: CMTP211398
    Certified Pre-Owned: Yes
    Listed since: 04-30-2025

  • New Listing
    $33,998
    fair price
    $1,039 above market
    • 40,617 miles
    • 22 City / 31 Hwy MPG
    • CarMax Miami (International Mall) (102 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Doral, FL / 102 miles away from Port Saint Lucie, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB5MA965944
    Stock: 27241429
    Certified Pre-Owned: No

Showing 1 - 21 out of 1,253 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.5 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (73%)
  • 4 star
    (21%)
  • 3 star
    (0%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2021 Mercedes-Benz E-Class in Port Saint Lucie, FL Values

Estimated values
2021 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$30,725$33,934$37,172
Clean$30,074$33,155$36,254
Average$28,989$31,857$34,725
Rough$27,578$30,171$32,738

The average list price of a used 2021 Mercedes-Benz E-Class in Port Saint Lucie, Florida is $34,533. The average mileage on a used Mercedes-Benz E-Class 2021 for sale in Port Saint Lucie, Florida is 40,164. Based on the average mileage of 40,164 for used 2021 Mercedes-Benz E-Class for sale in Port Saint Lucie, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2021 in Port Saint Lucie, Florida to be $28,989.

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