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428 listings
  • $36,393
    great price
    $4,915 below market
    • 34,799 miles
    • No accidents, 2 owners, personal use
    • 6cyl automatic
    • North Coast Mitsubishi Bedford (127 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Bedford, OH / 127 miles away from Ann Arbor, MI

    2021 Mercedes-Benz E-Class E 450 4MATIC® Mojave Silver Metallic 4D Sedan 3.0L I6 TurboBlind spot warning, Forward collision alert, Power folding side ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB0MA934134
    Stock: 934134T01
    Certified Pre-Owned: No
    Listed since: 02-11-2025

  • Price Drop
    $48,477
    great price
    $4,029 below market
    • 35,051 miles
    • No accidents, 3 owners, personal use
    • 6cyl automatic
    • Great Lakes Hyundai of Columbus (157 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 157 miles away from Ann Arbor, MI

    Excellent service history at a Dealership, Completely serviced and safety inspected, buy with confidence, Bluetooth, LOW MILES, Local Trade, MOONROOF,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/29 Highway)

    Listing Information:

    VIN: W1K1K5KB2MF157824
    Stock: 25C57B
    Certified Pre-Owned: No
    Listed since: 03-14-2025

  • Price Drop
    $34,985
    good price
    $2,298 below market
    • 35,552 miles
    • No accidents, 2 owners, personal use
    • 4cyl automatic
    • Bob Boyd Lincoln (152 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 152 miles away from Ann Arbor, MI

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB1MA973893
    Stock: A25403A
    Certified Pre-Owned: No
    Listed since: 03-24-2025

  • $37,850
    fair price
    $118 below market
    • 24,074 miles
    • No accidents, 1 owner, personal use
    • 4cyl automatic
    • Fishers Imports (198 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Fishers, IN / 198 miles away from Ann Arbor, MI

    Check out this beautiful 1 Owner, clean Carfax E350 with super low miles and extremely well equipped with Night package, Amg Line exterior, Premium pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB4MA974326
    Stock: WH4326
    Certified Pre-Owned: No
    Listed since: 11-25-2024

  • New Listing
    $39,590
    fair price
    $1,213 below market
    • 37,333 miles
    • 2 accidents, 2 owners, personal use
    • 6cyl automatic
    • Carvana - Cleveland (116 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cleveland, OH / 116 miles away from Ann Arbor, MI

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB1MA880309
    Stock: 2003572046
    Certified Pre-Owned: No
    Listed since: 03-25-2025

  • $40,000
    fair price
    $1,486 above market
    • 14,279 miles
    • No accidents, 3 owners, personal use only
    • 4cyl automatic
    • Sarchione Auto Gallery (153 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Canton, OH / 153 miles away from Ann Arbor, MI

    Just Arrived***2021 Mercedes Benz E Class E 350 4Matic Sedan***Premium Package***Night Package***AMG Line Exterior Package***Driver Assistance Package...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB2MA957380
    Stock: G2579A
    Certified Pre-Owned: No
    Listed since: 04-17-2025

  • Price Drop
    • 28,783 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • Mercedes-Benz of Centerville (182 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Centerville, OH / 182 miles away from Ann Arbor, MI

    2021 Mercedes-Benz E450 4MATIC Coupe offers a perfect blend of performance, luxury, and cutting-edge technology. Here are the standout features:Key Fe...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1K1J5KB6MF151205
    Stock: P12211
    Certified Pre-Owned: Yes
    Listed since: 01-28-2025

  • $35,600
    great price
    $6,469 below market
    • 18,743 miles
    • No accidents, 3 owners, personal use
    • 6cyl automatic
    • Ken Ganley Chrysler Dodge Jeep Ram Mentor (129 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Painesville, OH / 129 miles away from Ann Arbor, MI

    Alloy Wheels, Backup Camera, Bluetooth, Hands-Free, Clean Carfax, Cruise Control, Heated Seats, Keyless Entry, Leather Seats, Navigation, Power Locks,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: W1KZF6JB8LA836944
    Stock: 17775T
    Certified Pre-Owned: No
    Listed since: 04-23-2025

  • Price Drop
    • 15,516 miles
    • Frame damage reported, 1 owner, personal use
    • 4cyl automatic
    • Honda of Cleveland Heights (122 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cleveland Heights, OH / 122 miles away from Ann Arbor, MI

    2021 Mercedes-Benz E-Class E 350 4MATIC® designo Cardinal Red 4D Sedan Recent Arrival! I4Front & rear parking sensors, Blind spot warning, Multicont...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB4MA974780
    Stock: 974780F01
    Certified Pre-Owned: No
    Listed since: 04-25-2025

  • Price Drop
    $37,990
    great price
    $5,167 below market
    • 21,013 miles
    • No accidents, 1 owner, personal use only
    • 4cyl automatic
    • Unlimited Motors Westfield (199 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Westfield, IN / 199 miles away from Ann Arbor, MI

    Navigation, Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Blind Spot, Apple Play, E 350, 4D Sedan, I4, 9-Speed Automatic, RWD,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB9NB091058
    Stock: STK091058
    Certified Pre-Owned: No
    Listed since: 10-09-2024

  • $26,997
    great price
    $5,392 below market
    • 71,303 miles
    • No accidents, 1 owner, personal use only
    • 6cyl automatic
    • Honda of Mansfield (120 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Ontario, OH / 120 miles away from Ann Arbor, MI

    Priced below KBB Fair Purchase Price! 2020 Mercedes-Benz E-Class E 450 4MATIC® Diamond White 4MATIC® 3.0L V6 BiTurbo 9-Speed Automatic 4MATIC® 20/28 C...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: WDDZF6JB2LA725998
    Stock: M251434A
    Certified Pre-Owned: No
    Listed since: 01-15-2025

  • $48,990
    great price
    $5,986 below market
    • 61,273 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • Unlimited Motors Westfield (199 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Westfield, IN / 199 miles away from Ann Arbor, MI

    Navigation, Back Up Camera, Bluetooth, Heated Seats, Touch Screen, Vented Seats, Blind Spot, E-Class E 53 AMG® 4MATIC®, 2D Coupe, I6, 9-Speed Automati...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: W1K1J6BB8NF180048
    Stock: STK180048
    Certified Pre-Owned: No
    Listed since: 11-22-2024

  • Price Drop
    $30,449
    good price
    $2,016 below market
    • 37,636 miles
    • No accidents, 2 owners, personal use
    • 4cyl automatic
    • Randy Wise Buick GMC (37 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Fenton, MI / 37 miles away from Ann Arbor, MI

    2020 Mercedes-Benz E-Class E 350 4MATIC®.Certification Program Details: Our Car Bravo Certified Pre-Owned vehicles include a 6 Month or 6,000 Mile b...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: WDDZF8EB3LA703126
    Stock: B22194WH
    Certified Pre-Owned: No
    Listed since: 03-31-2025

  • Price Drop
    $38,290
    great price
    $2,812 below market
    • 13,541 miles
    • 2 accidents, 1 owner, personal use
    • 4cyl automatic
    • North Coast Mitsubishi Bedford (127 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Bedford, OH / 127 miles away from Ann Arbor, MI

    2022 Mercedes-Benz E-Class E 350 4MATIC® Polar White 4D Sedan I4Front and rear parking sensors, Power folding side view mirrors, Forward collision war...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB1NB029622
    Stock: 029622C01
    Certified Pre-Owned: No
    Listed since: 02-20-2025

  • Price Drop
    $40,550
    fair price
    $457 below market
    • 28,221 miles
    • No accidents, 2 owners, rental vehicle
    • 4cyl automatic
    • Fishers Imports (198 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Fishers, IN / 198 miles away from Ann Arbor, MI

    wow.. you can't find another one like this equipped perfectly with 18" upgraded wheels, Amg line package, Exterior lighting package, Pano roof, adapt...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB3NB025748
    Stock: I5748
    Certified Pre-Owned: No
    Listed since: 03-26-2025

  • Price Drop
    • 38,722 miles
    • No accidents, 1 owner, personal use
    • 4cyl automatic
    • Mercedes-Benz of North Olmsted (109 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in North Olmsted, OH / 109 miles away from Ann Arbor, MI

    BACK-UP CAMERA, BLUETOOTH HANDS FREE PHONE, CERTIFIED, HEATED SEATS, LEATHER, NAVIGATION, NO ACCIDENTS, PANORAMIC ROOF, WORRY FREE PRICING... WORRY FR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB0NB038764
    Stock: M8894
    Certified Pre-Owned: Yes
    Listed since: 04-03-2025

  • $43,998
    fair price
    $925 below market
    • 3,737 miles
    • No accidents, 1 owner, personal use
    • 4cyl automatic
    • Price Pro (47 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Maumee, OH / 47 miles away from Ann Arbor, MI

    Only 3737 Actual Miles!! Premium Pkg, Leather Seats, Heated Seats, Heated Steering Wheel, Navigation System, Sunroof, Interior Ambient Lighting, Keyle...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB3NB069121
    Stock: 25234JF
    Certified Pre-Owned: No
    Listed since: 04-11-2025

  • Price Drop
    • 35,440 miles
    • No accidents, 1 owner, personal use
    • 4cyl automatic
    • Mercedes-Benz of North Olmsted (109 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in North Olmsted, OH / 109 miles away from Ann Arbor, MI

    BACK-UP CAMERA, BLUETOOTH HANDS FREE PHONE, CERTIFIED, HEATED SEATS, LEATHER, NAVIGATION, NO ACCIDENTS, PANORAMIC ROOF, WORRY FREE PRICING... WORRY FR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB6NB010340
    Stock: M153874A
    Certified Pre-Owned: Yes
    Listed since: 04-01-2025

  • Price Drop
    $42,995
    fair price
    $817 below market
    • 34,641 miles
    • 1 accident, 2 owners, personal use
    • 6cyl automatic
    • Unlimited Motors Elwood (178 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Elwood, IN / 178 miles away from Ann Arbor, MI

    Navigation, Back Up Camera, Sunroof, Panoramic Sunroof, Bluetooth, Touch Screen, Heated Seats, Power Lift Gate, Apple Car Play, Blind Spot, Low Miles,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: WDDZF6BBXLA732714
    Stock: STK464428
    Certified Pre-Owned: No
    Listed since: 03-29-2025

  • Price Drop
    $38,495
    good price
    $2,040 below market
    • 31,931 miles
    • No accidents, 1 owner, personal use
    • 4cyl automatic
    • Contemporary Motorcar (186 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Erie, PA / 186 miles away from Ann Arbor, MI

    2022 Mercedes-Benz E-Class E 350 4MATIC® Graphite 21/29 City/Highway MPG

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB7NB016955
    Stock: M24-205A
    Certified Pre-Owned: No
    Listed since: 10-28-2024

  • $47,500
    fair price
    $1,054 above market
    • 20,163 miles
    • No accidents, 2 owners, personal use
    • 6cyl automatic
    • Unlimited Motors Westfield (199 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Westfield, IN / 199 miles away from Ann Arbor, MI

    Navigation, Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Vented Seats, Blind Spot, E-Class E 450, 2D Coupe, 3.0L I6 Turbo, 9-...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JB6NF185003
    Stock: STK185003
    Certified Pre-Owned: No
    Listed since: 08-21-2024

Showing 1 - 21 out of 428 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.5 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (73%)
  • 4 star
    (21%)
  • 3 star
    (0%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2021 Mercedes-Benz E-Class in Ann Arbor, MI Values

Estimated values
2021 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$34,365$37,954$41,576
Clean$33,637$37,083$40,550
Average$32,423$35,632$38,840
Rough$30,846$33,745$36,616

The average list price of a used 2021 Mercedes-Benz E-Class in Ann Arbor, Michigan is $40,005. The average mileage on a used Mercedes-Benz E-Class 2021 for sale in Ann Arbor, Michigan is 30,560. Based on the average mileage of 30,560 for used 2021 Mercedes-Benz E-Class for sale in Ann Arbor, MI and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2021 in Ann Arbor, Michigan to be $32,423.

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