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261 listings
  • New Listing
    • 45,738 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from TX to SC*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Houston, TX / 942 miles away from Charleston, SC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC091387
    Stock: 27163451
    Certified Pre-Owned: No

  • New Listing
    • 28,871 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Mark Jacobson Toyota (226 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Durham, NC / 226 miles away from Charleston, SC

    Come to Mark Jacobson Toyota and check out this. 2022 Lexus RX 450h F Sport In our two story indoor showroom! Certified. Eminent White Pearl AWD eCVT ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7NC075649
    Stock: P17114
    Certified Pre-Owned: No
    Listed since: 07-31-2025

  • New Listing
    Stock photo**
    $52,312
    fair price
    $492 above market
    • 36,740 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Cool Springs (448 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Brentwood, TN / 448 miles away from Charleston, SC

    Certified. CARFAX One-Owner.3.5L V6 DOHC VVT-i 24V, AWD, Parchment w/Semi-Aniline Leather Seat Trim.2022 Lexus RX 450h Luxury Eminent White PearlL/Cer...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC088246
    Stock: L12065
    Certified Pre-Owned: No
    Listed since: 07-30-2025

    • 29,999 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Lexington (441 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lexington, KY / 441 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXNC082966
    Stock: L5297
    Certified Pre-Owned: Yes
    Listed since: 06-28-2025

  • New Listing
    • 26,250 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Easterns Automotive Group of Sterling / Direct Car Buying (450 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sterling, VA / 450 miles away from Charleston, SC

    2022 Lexus RX 450h Black AWD eCVT 3.5L V6 DOHC VVT-i 24V, AWD, Black Artificial Leather, Apple CarPlay/Android Auto, Four wheel independent suspension...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC077542
    Stock: 162945
    Certified Pre-Owned: No
    Listed since: 06-12-2025

  • Stock photo**
    • 43,187 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lindsay Lexus of Alexandria (446 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Alexandria, VA / 446 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA5NC079909
    Stock: L49981A
    Certified Pre-Owned: No
    Listed since: 07-15-2025

  • Price Drop
    $43,749
    fair price
    $588 below market
    • 29,155 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Ramsey, NJ / 655 miles away from Charleston, SC

    CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,L...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC087552
    Stock: L17711T
    Certified Pre-Owned: No

  • New Listing
    Stock photo**
    • 76,150 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Cars Plus (233 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lenoir, NC / 233 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA0NC083481
    Stock: J83481
    Certified Pre-Owned: No
    Listed since: 08-01-2025

  • New Listing
    Stock photo**
    • 73,249 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hyundai of Columbia (449 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbia, TN / 449 miles away from Charleston, SC

    At Hyundai of Columbia, we re committed to a hassle-free, customer-first experience. If you want a good deal, you ve found it! Optional upgrades are a...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA8NC073642
    Stock: H15489
    Certified Pre-Owned: No
    Listed since: 07-23-2025

Showing 253 - 261 out of 261 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.5 out of 5 stars63 Reviews
Write a vehicle reviewSee all 63 reviews
  • 5 star
    (78%)
  • 4 star
    (11%)
  • 3 star
    (5%)
  • 2 star
    (2%)
  • 1 star
    (5%)
4.88 out of 5 stars

RX450h

ebaxley, 04/04/2011
2011 Lexus RX 450h 4dr SUV (3.5L 6cyl gas/electric hybrid CVT)
Overall, great. Fuel economy is better than Highlander Hybrid I owned before. Getting over 29mpg overall, over 30 if I use pure gas. About 26-27 on Interstate. Apparently 87 octane is OK, no pinging. Mpg no different with high-test. Features were quite onerous at first but"I'm catching on". Most disappointing feature is , by far, GPS. Map base is outdated, voice recognition poor and … some functions won't operate while moving. I realize you shouldn't be inputting while driving but sometimes you have a co-pilot. I have solved problem by mounting a Garmin on the dash. Marvelous ride!
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Used 2022 Lexus RX 450h in Charleston, SC Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$35,172$36,890$38,682
Clean$34,703$36,379$38,126
Average$33,922$35,528$37,199
Rough$32,907$34,421$35,994

The average list price of a used 2022 Lexus RX 450h in Charleston, South Carolina is $46,297. The average mileage on a used Lexus RX 450h 2022 for sale in Charleston, South Carolina is 43,260. Based on the average mileage of 43,260 for used 2022 Lexus RX 450h for sale in Charleston, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Charleston, South Carolina to be $33,922.

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