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275 listings
    • 30,285 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Butler Lexus of South Atlanta (270 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Union City, GA / 270 miles away from Charleston, SC

    **OEM CERTIFIED** Thank you for choosing BUTLER LEXUS OF SOUTH ATLANTA, this Atomic Silver 2022 Lexus RX 450h F SPORT Handling is a great choice! Chec...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA1NC076151
    Stock: RB8076
    Certified Pre-Owned: Yes
    Listed since: 06-12-2025

    • 75,196 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Johnson Lexus of Raleigh (226 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Raleigh, NC / 226 miles away from Charleston, SC

    Elevate your drive with this Certified 2022 Lexus RX 450h, a one-owner vehicle with 75,196 miles and a clean CARFAX. This luxury hybrid SUV blends Lex...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC078766
    Stock: P12111
    Certified Pre-Owned: Yes
    Listed since: 05-30-2025

  • New Listing
    • 36,169 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Billings, MT / 1,761 miles away from Charleston, SC

    CarFax No Accidents Reported,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steeri...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9LC044836
    Stock: 23179CG
    Certified Pre-Owned: No

  • Price Drop
    • 54,803 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Fort Myers (448 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Myers, FL / 448 miles away from Charleston, SC

    Ultra White exterior and CIRCUIT RED interior. Heated/Cooled Seats, NAV, Hybrid, Power Liftgate, All Wheel Drive, PANORAMIC-VIEW MONITOR W/RR CROSS-TR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXNC079937
    Stock: NC079937
    Certified Pre-Owned: Yes
    Listed since: 06-07-2025

  • New Listing
    Stock photo**
    $35,869
    fair price
    $128 above market
    • 75,138 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Lexington (441 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lexington, KY / 441 miles away from Charleston, SC

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXLC044425
    Stock: X37609B
    Certified Pre-Owned: No
    Listed since: 06-28-2025

  • New Listing
    • 21,644 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Johnson City Toyota (283 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Keyless Entry/Start
    Close

    Located in Johnson City, TN / 283 miles away from Charleston, SC

    Heated Seats, NAV, Hybrid, Back-Up Camera, Heated Rear Seat, Power Liftgate, All Wheel Drive, ACCESSORY PACKAGE, 12.3 NAVIGATION SYSTEM, HEATED & VENT...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA0LC047114
    Stock: TLC047114
    Certified Pre-Owned: No
    Listed since: 06-28-2025

    • 66,594 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Silver Spring (464 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Silver Spring, MD / 464 miles away from Charleston, SC

    2020 Lexus RX 450h Recent Arrival! CARFAX One-Owner. Clean CARFAX.Obsidian 3.5L V6 DOHC VVT-i 24V, AWD, Black Artificial Leather, 3.54 Axle Ratio, 4-W...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: Yes

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4LC051788
    Stock: 5D7645A
    Certified Pre-Owned: No
    Listed since: 06-12-2025

  • Price Drop
    • 35,601 miles
    • 1 accident, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Beaver Toyota of St. Augustine (220 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Saint Augustine, FL / 220 miles away from Charleston, SC

    Certified. EXCLUSIVE BEAVER CERTIFIED 7Year/100,000 Powertrain and 12 mos/12,000 mile Bumper to Bumper Included, 4.9 Star Dealer Rater Reviews, 4.7 St...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1LC055779
    Stock: A63483B
    Certified Pre-Owned: No
    Listed since: 05-31-2025

    • 49,378 miles
    • Frame damage reported, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Alpha Motor Sports (403 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 403 miles away from Charleston, SC

    ** OVER 30,000 VEHICLES SOLD, TWO LOCATION TO SERVE YOU, 400+ VEHICLES IN STOCK, visit www.AlphaMS.com to view our inventory, BEST PRICES IN TOWN **NA...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC088755
    Stock: S088755
    Certified Pre-Owned: No

  • Stock photo**
    • Not provided
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Ourisman Lexus of Rockville (463 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Rockville, MD / 463 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDAXNC076232
    Stock: 076232
    Certified Pre-Owned: No
    Listed since: 02-03-2025

  • Stock photo**
    • Not provided
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Ourisman Lexus of Rockville (463 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Rockville, MD / 463 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA0NC084371
    Stock: 084371
    Certified Pre-Owned: No
    Listed since: 03-19-2025

  • Price Drop
    $41,590
    great price
    $3,975 below market
    • 54,860 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Oklahoma City, OK / 1,020 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA6MC070491
    Stock: 2003767922
    Certified Pre-Owned: No
    Listed since: 05-30-2025

    • 17,324 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in San Antonio, TX / 1,120 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA8MC070900
    Stock: 2003186833
    Certified Pre-Owned: No
    Listed since: 06-10-2025

  • Price Drop
    • 33,886 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hilton Head Lexus (69 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Hardeeville, SC / 69 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA9MC065896
    Stock: H25312A
    Certified Pre-Owned: Yes
    Listed since: 03-01-2025

  • New Listing
    Stock photo**
    $43,997
    good price
    $3,541 below market
    • 28,723 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Sarasota (411 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 411 miles away from Charleston, SC

    **LEXUS L/CERTIFIED VEHICLE * 6 YEARS UNLIMITED MILEAGE FACTORY WARRANTY** Clean CARFAX. CARFAX One-Owner. LEATHER, REAR-VIEW CAMERA, BLIND SPOT WARNI...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXMC068290
    Stock: C093573A
    Certified Pre-Owned: Yes
    Listed since: 06-27-2025

    • 50,647 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 976 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXMC068807
    Stock: 2003797747
    Certified Pre-Owned: No
    Listed since: 06-16-2025

  • Price Drop
    $35,998
    good price
    $1,571 below market
    • 84,512 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Classic Toyota of North Wilkesboro (242 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in North Wilkesboro, NC / 242 miles away from Charleston, SC

    This 2021 Lexus RX RX 450h F SPORT Handling, has a Ultra White exterior and an Black interior color. 84512 miles. Stock Number PT4419A. You can connec...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXMC062358
    Stock: PT4419A
    Certified Pre-Owned: No
    Listed since: 04-25-2025

  • Price Drop
    • 46,421 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Greenville (196 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Keyless Entry/Start
    Close

    Located in Greenville, SC / 196 miles away from Charleston, SC

    Heated/Cooled Seats, Moonroof, Navigation, Heated Rear Seat, Power Liftgate, All Wheel Drive, Aluminum Wheels, 12.3 NAVIGATION SYSTEM W/MARK LEVINS......

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXMC071898
    Stock: AMC071898
    Certified Pre-Owned: Yes
    Listed since: 06-02-2025

  • New Listing
    • 40,610 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 976 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA9MC064883
    Stock: 2003831751
    Certified Pre-Owned: No
    Listed since: 06-21-2025

    • 25,837 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Houston, TX / 943 miles away from Charleston, SC

    Low Mileage,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2MC069174
    Stock: MC069174P
    Certified Pre-Owned: No

  • $43,251
    fair price
    $684 above market
    • 44,731 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Genesis of South Richmond (352 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in North Chesterfield, VA / 352 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7MC067419
    Stock: G20937A
    Certified Pre-Owned: No
    Listed since: 05-02-2025

Showing 211 - 231 out of 275 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.5 out of 5 stars63 Reviews
Write a vehicle reviewSee all 63 reviews
  • 5 star
    (78%)
  • 4 star
    (11%)
  • 3 star
    (5%)
  • 2 star
    (2%)
  • 1 star
    (5%)
4.88 out of 5 stars

RX450h

ebaxley, 04/04/2011
2011 Lexus RX 450h 4dr SUV (3.5L 6cyl gas/electric hybrid CVT)
Overall, great. Fuel economy is better than Highlander Hybrid I owned before. Getting over 29mpg overall, over 30 if I use pure gas. About 26-27 on Interstate. Apparently 87 octane is OK, no pinging. Mpg no different with high-test. Features were quite onerous at first but"I'm catching on". Most disappointing feature is , by far, GPS. Map base is outdated, voice recognition poor and … some functions won't operate while moving. I realize you shouldn't be inputting while driving but sometimes you have a co-pilot. I have solved problem by mounting a Garmin on the dash. Marvelous ride!
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Used 2022 Lexus RX 450h in Charleston, SC Values

Estimated values
2022 Lexus RX 450h F SPORT Handling 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$38,018$39,782$41,623
Clean$37,511$39,231$41,024
Average$36,667$38,313$40,027
Rough$35,569$37,119$38,730

The average list price of a used 2022 Lexus RX 450h in Charleston, South Carolina is $42,478. The average mileage on a used Lexus RX 450h 2022 for sale in Charleston, South Carolina is 41,541. Based on the average mileage of 41,541 for used 2022 Lexus RX 450h for sale in Charleston, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Charleston, South Carolina to be $36,667.

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