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339 listings
- $33,994good price$2,545 below market
- 46,701 miles
- No accidents, 2 owners, personal use only
- 20 City / 28 Hwy MPG
- AutoNation Ford Jacksonville (246 mi away)
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Located in Jacksonville, FL / 246 miles away from Panama City, FL
MoonroofIntuitive Park Assist W/Auto BrakingSun/MoonroofPremium Paint (Pj)Accessory PackageDoor Edge Film By 3MLane Keeping AssistKeyless Start...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B21M5048610
Stock: M5048610
Certified Pre-Owned: No
Listed since: 07-23-2025 - $22,500good price$3,003 below market
- 50,286 miles
- 1 accident, 3 owners, corporate fleet vehicle
- 20 City / 28 Hwy MPG
- Premium Cars (246 mi away)
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Located in Tampa, FL / 246 miles away from Panama City, FL
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1D24K5033913
Stock: 033913
Certified Pre-Owned: No
Listed since: 03-17-2025 - $40,886fair price$1,182 above market
- 11,292 miles
- No accidents, 1 owner, personal use only
- 20 City / 28 Hwy MPG
- Lexus of Clearwater (232 mi away)
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Located in Clearwater, FL / 232 miles away from Panama City, FL
Intuitive Park Assist W/Auto BrakingAccessory PackageLane Keeping AssistKeyless StartRear SpoilerCooled Front Seat(S)Atomic SilverBlack W/Black...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25M5041711
Stock: M5041711
Certified Pre-Owned: Yes
Listed since: 07-18-2025 - $39,983good price$1,938 below market
- 27,542 miles
- 1 accident, 1 owner, personal use
- 19 City / 26 Hwy MPG
- Stokes-Trainor Chevrolet Buick GMC (370 mi away)
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Located in Newberry, SC / 370 miles away from Panama City, FL
Vehicle DetailsIntroducing the 2021 Lexus IS 350 F SPORT, a remarkable blend of performance, luxury, and technology, now available with 27,527...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29M5020260
Stock: 1251443A
Certified Pre-Owned: No
Listed since: 07-16-2025 - Price Drop$36,590fair price$267 below market
- 50,473 miles
- No accidents, 3 owners, personal use
- 20 City / 28 Hwy MPG
- Carvana - Charlotte (448 mi away)
- Home delivery*
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Located in Charlotte, NC / 448 miles away from Panama City, FL
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B24M5044597
Stock: 2003857408
Certified Pre-Owned: No
Listed since: 06-29-2025 - $39,892fair price$1,052 above market
- 31,310 miles
- No accidents, 2 owners, personal use
- 20 City / 28 Hwy MPG
- Buddy Chevrolet (260 mi away)
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Located in Decatur, GA / 260 miles away from Panama City, FL
White 2021 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V **ALLOY WHEELS, **APPLE CARPLAY/ANDROID AUTO, **BLIND SPOT DETECTION...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26M5047839
Stock: M5047839P
Certified Pre-Owned: No
Listed since: 07-02-2025 - $37,325fair price$255 above market
- 40,586 miles
- No accidents, 4 owners, personal use only
- 20 City / 28 Hwy MPG
- Herlong Ford (331 mi away)
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Located in Edgefield, SC / 331 miles away from Panama City, FL
Lexus IS 350 F SPORT 3.5L V6 DOHC Dual VVT-i 24V 8-Speed Automatic350 F Sport Artificial Leather, AM/FM/CD Player, CD player, Cruise Control, Dual Fr...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B23M5041268
Stock: 5374V
Certified Pre-Owned: No
Listed since: 05-07-2025 - Price Drop$39,020fair price$731 above market
- 23,891 miles
- 1 accident, 1 owner, personal use
- 20 City / 28 Hwy MPG
- ALM Kia South (243 mi away)
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Located in Union City, GA / 243 miles away from Panama City, FL
ACCESSORY PACKAGE 2 - Z2..WHITE W/BLACK, F SPORT NULUXE SEAT TRIM..SUN/MOONROOF..PREMIUM SOUND SYSTEM..PREMIUM SYNTHETIC SEATS..LANE DEPARTURE WARNING...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22M5043433
Stock: M5043433
Certified Pre-Owned: No
Listed since: 06-06-2025 - Price Drop$35,900fair price$337 below market
- 59,659 miles
- 1 accident, 2 owners, personal use
- 19 City / 26 Hwy MPG
- Countryside Chrysler Dodge Jeep Ram (231 mi away)
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Located in Jackson, GA / 231 miles away from Panama City, FL
Vehicle DetailsDiscover the thrill of driving with this exceptional 2021 Lexus IS 350 F SPORT. With its powerful V6, 3.5L engine and All-Wheel...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29M5020758
Stock: P4637A
Certified Pre-Owned: No
Listed since: 07-16-2025 - New Listing$36,209fair price$11 above market
- 70,573 miles
- 1 accident, 3 owners, personal use
- 20 City / 28 Hwy MPG
- Nalley Lexus Smyrna (265 mi away)
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Located in Smyrna, GA / 265 miles away from Panama City, FL
RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22M5041911
Stock: NLSS213114
Certified Pre-Owned: Yes
Listed since: 07-30-2025 - $37,986great price$5,796 below market
- 27,385 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Kendall Dodge Chrysler Jeep Ram (449 mi away)
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Located in Miami, FL / 449 miles away from Panama City, FL
Priced below KBB Fair Purchase Price! CARFAX One-Owner. Clean CARFAX. Odometer is 4375 miles below market average! AWD, Black Artificial Leather, ABS ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XN5027171
Stock: D5T733807A
Certified Pre-Owned: No
Listed since: 06-20-2025 - $33,990
- 28,860 miles
- No accidents, 1 owner, personal use
- 20 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Phoenix, AZ / 1,561 miles away from Panama City, FL
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1D22K5034137
Stock: 2003891766
Certified Pre-Owned: No
Listed since: 07-11-2025 - $43,337great price$6,309 below market
- 14,628 miles
- No accidents, 1 owner, personal use only
- 20 City / 28 Hwy MPG
- Lexus of Clearwater (232 mi away)
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Located in Clearwater, FL / 232 miles away from Panama City, FL
The following items have been reconditioned on this vehicle: new tires! Navigation Package W/Mark Levinson AudioWheels: 19" Matte Black Bbs Forged...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27P5071992
Stock: P5071992
Certified Pre-Owned: Yes
Listed since: 06-25-2025 - Price Drop
- 31,533 miles
- No accidents, 2 owners, personal use
- 20 City / 28 Hwy MPG
- Leesburg Volkswagen (251 mi away)
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Located in Leesburg, FL / 251 miles away from Panama City, FL
The price does not include tax, tag, license, an electronic filing fee of $449.00**, a private tag agency fee of $199.00**, and a predelivery service ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25M5041109
Stock: V9750A
Certified Pre-Owned: No
Listed since: 07-26-2025 - Price Drop$42,919great price$7,005 below market
- 28,609 miles
- No accidents, 1 owner, personal use only
- 19 City / 26 Hwy MPG
- Athens Ford (289 mi away)
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Located in Athens, GA / 289 miles away from Panama City, FL
Clean CARFAX.2023 Lexus IS 350 F SPORT 3.5L V6 DOHC Dual VVT-i 24V AWD Ultra White2023 Lexus IS, Super clean, Clean Carfax, Local Trade In, Forward co...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20P5031734
Stock: KD93904A
Certified Pre-Owned: No
Listed since: 06-21-2025 - Price Drop$41,988great price$5,053 below market
- 12,580 miles
- No accidents, 1 owner, personal use only
- 20 City / 28 Hwy MPG
- Cecil Clark Chevrolet (250 mi away)
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Located in Leesburg, FL / 250 miles away from Panama City, FL
This 2023 Lexus IS 350 F SPORT is a vehicle that is sure to turn heads. Boasting a low mileage of 12,580 miles, this car is sure to be reliable and ef...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B28P5071290
Stock: 25207A
Certified Pre-Owned: No
Listed since: 05-29-2025 - New Listing
- 37,615 miles
- No accidents, 2 owners, personal use only
- 20 City / 28 Hwy MPG
- Mercedes-Benz of North Orlando (278 mi away)
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Located in Sanford, FL / 278 miles away from Panama City, FL
MoonroofIntuitive Park Assist W/Auto BrakingSun/MoonroofPremium Paint (Pj)Accessory PackageLane Keeping AssistKeyless StartRear SpoilerCooled ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22M5042444
Stock: M5042444
Certified Pre-Owned: No
Listed since: 07-26-2025 - Price Drop$36,561great price$3,685 below market
- 54,455 miles
- No accidents, 2 owners, personal use only
- 20 City / 28 Hwy MPG
- Lexus of Fort Myers (342 mi away)
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Located in Fort Myers, FL / 342 miles away from Panama City, FL
Heated/Cooled Seats, Sunroof, Navigation, Onboard Communications System, Satellite Radio, iPod/MP3 Input, POWER TILT & SLIDE MOONROOF, NAVIGATION PACK...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25N5053312
Stock: N5053312
Certified Pre-Owned: Yes
Listed since: 06-19-2025 - Price Drop$37,499great price$4,194 below market
- 28,672 miles
- No accidents, 1 owner, personal use
- 20 City / 28 Hwy MPG
- Brickell Chrysler Dodge Jeep Ram (452 mi away)
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Located in Miami, FL / 452 miles away from Panama City, FL
Infrared 2023 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Black w/Perforated NuLuxe Seat Trim.Find Your Perfect Pre-Owned...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26P5068825
Stock: KJ1762A
Certified Pre-Owned: No
Listed since: 06-30-2025 - New Listing
- 91,087 miles
- 19 City / 26 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Cincinnati, OH / 619 miles away from Panama City, FL
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
21 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHCZ1D2XK5016389
Stock: 2003908173
Certified Pre-Owned: No
Listed since: 07-31-2025 - $34,999good price$2,142 below market
- 51,653 miles
- 1 accident, 3 owners, personal use
- 20 City / 28 Hwy MPG
- CarsCatch Used Car Sales (277 mi away)
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Located in Woodstock, GA / 277 miles away from Panama City, FL
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26M5040342
Stock: 12247
Certified Pre-Owned: No
Showing 64 - 84 out of 339 listings
Consumer Reviews for the Lexus IS 350
Read recent reviews for the Lexus IS 350
Quick!
johnlaregion, 10/18/2011
2012 Lexus IS 350 4dr Sedan (3.5L 6cyl 6A)
Just traded in an 07 3-series. BMW had so many problems with that car and having heard so many great things about Lexus build quality and dealership service I gave the IS350 a try. The car is so fast! It handles in turns better than a BMW and way more features for the dollar. First and definitely not my last Lexus!!
Used 2021 Lexus IS 350 in Panama City, FL Values
Estimated values
2021 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $32,019 | $34,224 | $36,440 |
| Clean | $31,398 | $33,531 | $35,670 |
| Average | $30,364 | $32,375 | $34,385 |
| Rough | $29,020 | $30,872 | $32,716 |
The average list price of a used 2021 Lexus IS 350 in Panama City, Florida is $37,114. The average mileage on a used Lexus IS 350 2021 for sale in Panama City, Florida is 39,019. Based on the average mileage of 39,019 for used 2021 Lexus IS 350 for sale in Panama City, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2021 in Panama City, Florida to be $30,364.
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