This is a decent vehicle with so-so amenities, but has a reliable engine. If you can find one with low mileage with a low price, here are a few things to look for that I have found at over 200,000 to date: have windows up and listen for engine when at idle and then at driving. Engine mounts tend to break easily. Check transmission oil pan for leaks. Check CV boots for tears, and listen for any clicking noises when you turn wheels while driving at parking lot speeds. Make sure A/C and fan(s) blow properly with no strange noises.
Used to be the VCR when few other makes had anything, but DVD players are the hip thing now.
Nissan has addressed all the problems by finally canceling the contract with Ford and building the Quest itself.