New dad with rapidly-growing infant. Reliability, comfort, convenience were top considerations. Like other reviewers, compared Odyssey to Sienna, Quest, VW, as well as against large SUVs. Found Odyssey to be best combination of features/utility/design for the price and for our needs. Purchased end-of-year model with 40 miles on odometer for about $1600 under invoice. Drives more like a car (albeit a Honda, and not a BMW), surprisingly roomy, cavernous cargo space when 3rd row is folded down, intuitive/ingenious fold-down 3rd row, trouble-free through first 500 miles. Solid feel throughout. Plastic dash, but that's what you get for about $25K.
Honda-reliable, comfy, easy to use fold-down seats, powered sliding doors, nice exterior look, feels solid.
Louder-than-expected freeway noise (just slightly less than my MB E-class with sports package tires), somewhat awkward heat/AC system (where's the "on" button?), subpar speakers.