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675 listings
    • 30,425 miles
    • No accidents, 1 owner, personal use
    • 21 City / 29 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Ann Arbor, MI / 466 miles away from Winston Salem, NC

    Rare Find,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Navigation System,Pr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB0NB063947
    Stock: NB063947P
    Certified Pre-Owned: No

  • New Listing
    • 32,068 miles
    • No accidents, 2 owners, personal use
    • 6cyl automatic
    • Carvana (In-stock online)
    • Home delivery*
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sacramento, CA / 2,252 miles away from Winston Salem, NC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JB3NF173679
    Stock: 2003742421
    Certified Pre-Owned: No
    Listed since: 05-21-2025

    • 50,232 miles
    • No accidents, 2 owners, personal use
    • 23 City / 32 Hwy MPG
    • CarMax Bristol (117 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Bristol, TN / 117 miles away from Winston Salem, NC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/32 Highway)

    Listing Information:

    VIN: WDDZF8DB9LA740537
    Stock: 27343125
    Certified Pre-Owned: No

    • 63,910 miles
    • No accidents, 1 owner, personal use only
    • 7 Seats, 21 City / 28 Hwy MPG
    • Stevenson-Hendrick Honda Wilmington (187 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Wilmington, NC / 187 miles away from Winston Salem, NC

    Elevate your driving experience with this *2022 Mercedes-Benz E450 4MATIC® All-Terrain*, a luxurious and versatile wagon finished in *Graphite Grey Me...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: W1KZH6ABXNB009146
    Stock: P11356
    Certified Pre-Owned: No
    Listed since: 04-14-2025

    • 37,899 miles
    • No accidents, 1 owner, personal use only
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of Myrtle Beach (182 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Myrtle Beach, SC / 182 miles away from Winston Salem, NC

    Mercedes-Benz [Certified]. 2022 Mercedes-Benz E 53 AMG 4MATIC CARFAX One-Owner. Clean CARFAX.$82,675 Original MSRP$6,625 In Premium OptionsFactory war...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB7NB037250
    Stock: M25594A
    Certified Pre-Owned: Yes
    Listed since: 01-30-2025

    • 47,542 miles
    • No accidents, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Los Angeles, CA / 2,141 miles away from Winston Salem, NC

    CarFax No Accidents Reported,CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Keyless Start,Navigati...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB9NB054009
    Stock: 20751C
    Certified Pre-Owned: No

    • 46,562 miles
    • 1 accident, 1 owner, personal use only
    • 23 City / 30 Hwy MPG
    • Mercedes-Benz of Greensboro (21 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Greensboro, NC / 21 miles away from Winston Salem, NC

    Certified. Priced below KBB Fair Purchase Price!CARFAX One-Owner.23/30 City/Highway MPG 2022 Mercedes-Benz E-Class E 450 4D SedanMercedes-Benz Certifi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB7NB006056
    Stock: G25382A
    Certified Pre-Owned: Yes
    Listed since: 04-10-2025

  • New Listing
    $38,999
    great price
    $3,818 below market
    • 13,261 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 30 Hwy MPG
    • Mercedes-Benz of Charlottesville (166 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Charlottesville, VA / 166 miles away from Winston Salem, NC

    BOUGHT NEW SERVICED AND RECENTLY TRADED HERE AT FLOW MERCEDES OF CHARLOTTESVILLE** GREAT SERVICE HISTORY ** LOCAL TRADE ** SUPER LOW MILES ** HEATED S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB0MA951609
    Stock: 37P0165
    Certified Pre-Owned: Yes
    Listed since: 04-05-2025

  • New Listing
    • 41,481 miles
    • 1 accident, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Lake Norman INFINITI (56 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Cornelius, NC / 56 miles away from Winston Salem, NC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB0NB026373
    Stock: PM12522
    Certified Pre-Owned: No
    Listed since: 02-12-2025

  • $57,920
    good price
    $3,033 below market
    • 2,774 miles
    • No accidents, 1 owner, personal use only
    • 24 City / 33 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Portland, OR / 2,288 miles away from Winston Salem, NC

    CarFax No Accidents Reported,CarFax 1-Owner,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless Start,Na...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB5SA099264
    Stock: SA099264R
    Certified Pre-Owned: No

  • $46,950
    fair price
    $3,644 below market
    • 40,993 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • Team Chevrolet of Swansboro (199 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Swansboro, NC / 199 miles away from Winston Salem, NC

    2021 Mercedes-Benz E-Class E 450 4MATIC **CARFAX CERTIFIED HISTORY*** (*FLORIDA ORIGIN**) Low Mileage!Check out all these great options 13 Speakers, 4...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/29 Highway)

    Listing Information:

    VIN: W1K1K5KB6MF151332
    Stock: SP3165
    Certified Pre-Owned: No
    Listed since: 01-23-2025

  • $68,998
    fair price
    $595 below market
    • 2,119 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 31 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Ann Arbor, MI / 466 miles away from Winston Salem, NC

    Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless Start,Navigation System,Remote Start,Satellite Radio...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLF6BB1SA114234
    Stock: RL114234
    Certified Pre-Owned: No

  • $37,499
    good price
    $1,041 below market
    • 31,389 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Mercedes-Benz of Kingsport (132 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Kingsport, TN / 132 miles away from Winston Salem, NC

    Certified. Mercedes-Benz Certified Pre-Owned Details: * Includes Trip Interruption Reimbursement and 7 days/500 miles Exchange Privilege * Transferabl...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB8MA979836
    Stock: M10648
    Certified Pre-Owned: Yes
    Listed since: 04-04-2025

  • Price Drop
    $34,799
    fair price
    $186 below market
    • 45,473 miles
    • No accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Toyota of North Charlotte (60 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntersville, NC / 60 miles away from Winston Salem, NC

    **CARFAX-CLEAN/NO ISSUES**, 4-Way Power Lumbar Support, Anti-whiplash front head restraints, Apple CarPlay/Android Auto, Emergency communication syste...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA967608
    Stock: TMA967608
    Certified Pre-Owned: No
    Listed since: 05-13-2025

  • Price Drop
    $32,950
    good price
    $1,576 below market
    • 38,422 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Los Angeles, CA / 2,141 miles away from Winston Salem, NC

    CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless Start,Navigation System...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA990709
    Stock: 20829C
    Certified Pre-Owned: No

  • Price Drop
    $36,219
    fair price
    $586 below market
    • 24,233 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Fred Anderson Acura (148 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Greenville, SC / 148 miles away from Winston Salem, NC

    Key Features & Packages:Technology & Comfort:Bluetooth , Rear View Camera, Heated Front Seats, Heated Steering Wheel, Power Moonroof, Power Driver & ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB3MA924454
    Stock: MA924454P
    Certified Pre-Owned: No
    Listed since: 05-20-2025

  • $60,560
    fair price
    $1,788 above market
    • 2,525 miles
    • No accidents, 1 owner, personal use only
    • 25 City / 33 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Los Angeles, CA / 2,141 miles away from Winston Salem, NC

    CarFax No Accidents Reported,CarFax 1-Owner,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless Start,Na...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB9SA122899
    Stock: 20815SL
    Certified Pre-Owned: No

  • Price Drop
    $31,339
    fair price
    $36 below market
    • 43,697 miles
    • No accidents, 4 owners, personal use only
    • 6cyl automatic
    • Auction Direct USA (86 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Raleigh, NC / 86 miles away from Winston Salem, NC

    Clean CARFAX. Auction Direct is proud to present you with another True Market Priced Pre-Owned Vehicle. This 2019 Mercedes-Benz E-Class E 450 is loade...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: WDD1J6HBXKF082514
    Stock: AD01045
    Certified Pre-Owned: No
    Listed since: 05-09-2025

  • Price Drop
    $34,989
    fair price
    $521 below market
    • 43,380 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Dick Dyer & Associates (148 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbia, SC / 148 miles away from Winston Salem, NC

    2021 Mercedes-Benz Certified Pre-Owned E350 RWD Sedan **CLEAN CARFAX**, **1 OWNER**, **PREMIUM PKG**, **NAVIGATION**.**BLIND SPOT ASSIST**, **AMG LINE...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA920432
    Stock: P6799
    Certified Pre-Owned: Yes
    Listed since: 02-04-2025

  • New Listing
    • 16,099 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NV to NC*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Las Vegas, NV / 1,941 miles away from Winston Salem, NC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MA935185
    Stock: 27132209
    Certified Pre-Owned: No

  • Stock photo**
    $38,499
    good price
    $838 below market
    • 19,999 miles
    • No accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Bob King Autohaus (186 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, NC / 186 miles away from Winston Salem, NC

    Clean CARFAX. Priced below KBB Fair Purchase Price!2021 Mercedes-Benz E-Class E 350 Local Trade In, Active Parking Assist, AIR BODY CONTROL Air Suspen...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB9MB004712
    Stock: M3480A
    Certified Pre-Owned: Yes
    Listed since: 03-27-2025

Showing 85 - 105 out of 675 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.2 out of 5 stars31 Reviews
Write a vehicle reviewSee all 31 reviews
  • 5 star
    (65%)
  • 4 star
    (16%)
  • 3 star
    (6%)
  • 2 star
    (3%)
  • 1 star
    (10%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2022 Mercedes-Benz E-Class in Winston Salem, NC Values

Estimated values
2022 Mercedes-Benz E-Class AMG E 53 4dr Sedan AWD (3.0L 6cyl Twincharger gas/electric mild hybrid 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$45,037$47,875$50,849
Clean$44,253$46,941$49,752
Average$42,947$45,386$47,925
Rough$41,249$43,364$45,549

The average list price of a used 2022 Mercedes-Benz E-Class in Winston Salem, North Carolina is $44,076. The average mileage on a used Mercedes-Benz E-Class 2022 for sale in Winston Salem, North Carolina is 32,118. Based on the average mileage of 32,118 for used 2022 Mercedes-Benz E-Class for sale in Winston Salem, NC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2022 in Winston Salem, North Carolina to be $42,947.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.