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1,113 listings
  • Price Drop
    $33,990
    fair price
    $800 above market
    • 27,123 miles
    • 1 accident, 2 owners, corporate fleet vehicle
    • 22 City / 31 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Indianapolis, IN / 946 miles away from Fort Myers, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB3MA915477
    Stock: 2003681276
    Certified Pre-Owned: No
    Listed since: 07-09-2025

  • Price Drop
    $39,590
    fair price
    $359 below market
    • 17,806 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 30 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Richmond, VA / 806 miles away from Fort Myers, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB2MA965852
    Stock: 2004000839
    Certified Pre-Owned: No
    Listed since: 08-22-2025

  • $36,247
    fair price
    $84 above market
    • 36,093 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 31 Hwy MPG
    • Crown Eurocars (101 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pinellas Park, FL / 101 miles away from Fort Myers, FL

    *Exterior Lighting Package*Night Package*AMG Line Exterior Package*Premium Package*Blind Spot Assist*Center Console in Natural Grain Black Ash Wood*He...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA922598
    Stock: 615199A
    Certified Pre-Owned: Yes
    Listed since: 07-17-2025

  • New Listing
    Stock photo**
    • 34,648 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 30 Hwy MPG
    • Fields Motorcars (106 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Lakeland, FL / 106 miles away from Fort Myers, FL

    CARFAX One-Owner. Clean CARFAX. 2021 Mercedes-Benz E-Class 4MATIC 4MATIC 9-Speed AutomaticCertified. Mercedes-Benz Certified Pre-Owned Details: * 165+...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB5MB000383
    Stock: LRL6620A
    Certified Pre-Owned: Yes
    Listed since: 08-31-2025

  • Price Drop
    $35,995
    fair price
    $216 below market
    • 46,925 miles
    • No accidents, 1 owner, personal use only
    • 6cyl automatic
    • Mercedes-Benz of Pembroke Pines (104 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Pembroke Pines, FL / 104 miles away from Fort Myers, FL

    Black/Saddle Brown; Amg ® Nappa Leather UpholsteryAmg ® Performance Exhaust SystemWheels: 20" Amg ® Twin 5-Spk W/Black AccentsAmg ®...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: WDD1J6BB0KF085978
    Stock: KF085978
    Certified Pre-Owned: No
    Listed since: 08-26-2025

  • $39,950
    fair price
    $3,029 above market
    • 30,434 miles
    • No accidents, 2 owners, personal use only
    • 6cyl automatic
    • Right Choice Auto Sales (111 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pompano Beach, FL / 111 miles away from Fort Myers, FL

    RARE AND ABSOLUTELY GORGEOUS E450 COUPE * $70,010 ORIGINAL STICKER * CLEAN CARFAX * ONLY 30K MILES * CARFAX CERTIFIED WELL-MAINTAINED * GARAGE-KEPT FL...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1K1J5JB2MF150781
    Stock: 2224
    Certified Pre-Owned: No
    Listed since: 06-04-2025

  • New Listing
    Stock photo**
    $52,991
    fair price
    $832 below market
    • 62,777 miles
    • No accidents, 2 owners, personal use only
    • 22 City / 29 Hwy MPG
    • Fields Motorcars (106 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Lakeland, FL / 106 miles away from Fort Myers, FL

    CARFAX One-Owner. 2021 Mercedes-Benz E-Class 4MATIC 4MATIC 9-Speed AutomaticMercedes Benz Certified, One Owner, Clean Carfax History, Active Distance ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB4MA945983
    Stock: LP6573A
    Certified Pre-Owned: Yes
    Listed since: 08-28-2025

  • $34,590
    fair price
    $723 above market
    • 23,739 miles
    • No accidents, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Birmingham, AL / 563 miles away from Fort Myers, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA983093
    Stock: 2003703473
    Certified Pre-Owned: No
    Listed since: 06-04-2025

  • $58,272
    fair price
    $801 above market
    • 24,244 miles
    • No accidents, 1 owner, personal use
    • 22 City / 29 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Los Angeles, CA / 2,218 miles away from Fort Myers, FL

    CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Rare Find,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Li...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB2MA966976
    Stock: 20905P
    Certified Pre-Owned: No

  • New Listing
    $46,795
    fair price
    $1,807 above market
    • 45,990 miles
    • No accidents, 3 owners, personal use only
    • 6cyl automatic
    • Subaru of Fort Myers (3 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Myers, FL / 3 miles away from Fort Myers, FL

    AMG Bodystyling, AMG Floor Mats, AMG Line, Galvanized Shift Paddles, Multi-Function Sports Steering Wheel w/Flat Bottom, 13 Speakers, 4-Way Lumb...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1K1K5JB3MF149863
    Stock: IS49863
    Certified Pre-Owned: No
    Listed since: 03-10-2025

  • $30,250
    fair price
    $264 below market
    • 45,912 miles
    • 2 accidents, 1 owner, personal use only
    • 22 City / 31 Hwy MPG
    • Porsche Clearwater (107 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Clearwater, FL / 107 miles away from Fort Myers, FL

    2021 Mercedes-Benz E-Class E 350 Active Parking Assist, Blind Spot Assist, Burmester Surround Sound System, Nappa Leather Steering Wheel, Premium Pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB5MA874382
    Stock: P513832
    Certified Pre-Owned: No
    Listed since: 08-03-2025

  • Price Drop
    $36,998
    fair price
    $840 above market
    • 30,798 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from MD to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in White Marsh, MD / 939 miles away from Fort Myers, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB6MA944910
    Stock: 27018456
    Certified Pre-Owned: No

  • New Listing
    $32,590
    fair price
    $485 below market
    • 52,265 miles
    • 22 City / 31 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Atlanta, GA / 522 miles away from Fort Myers, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7MA961751
    Stock: 2003949370
    Certified Pre-Owned: No
    Listed since: 07-31-2025

    • 40,300 miles
    • No accidents, 1 owner, personal use only
    • 7 Seats, 22 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Los Angeles, CA / 2,218 miles away from Fort Myers, FL

    CarFax 1-Owner,Rare Find,3rd Row Seat,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (22 City/28 Highway)

    Listing Information:

    VIN: W1KZH6AB7MA941289
    Stock: 5488450-1
    Certified Pre-Owned: No

  • Price Drop
    • 59,768 miles
    • Frame damage reported, 3 owners, corporate fleet vehicle
    • 6cyl automatic
    • North Miami Mitsubishi (112 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Miami Gardens, FL / 112 miles away from Fort Myers, FL

    KBB Fair Market Range High: $35,253Black 2019 Mercedes-Benz E-Class E 450 3.0L V6 BiTurbo 9-Speed Automatic RWDSTOP OVERPAYING!!! SAVE THOUSANDS O...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: WDD1K6HB8KF082525
    Stock: 082525F01
    Certified Pre-Owned: No
    Listed since: 07-01-2025

  • New Listing
    Stock photo**
    $33,669
    good price
    $1,769 below market
    • 50,091 miles
    • 1 accident, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Daytona Beach (189 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Daytona Beach, FL / 189 miles away from Fort Myers, FL

    Certified.2021 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic I4 Mojave Silver MetallicThis vehicle Includes the Following Features and Options: Me...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA946077
    Stock: ZA946077
    Certified Pre-Owned: Yes
    Listed since: 09-01-2025

  • $30,499
    fair price
    $572 above market
    • 63,322 miles
    • 1 accident, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of South Orlando (136 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orlando, FL / 136 miles away from Fort Myers, FL

    Black WE DELIVER TO YOUR HOME OR OFFICE. 115V AC Power Outlet, 4-Way Power Lumbar Support, Active Parking Assist, AMG Line Exterior, Augmented Video f...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA905433
    Stock: TB505925A
    Certified Pre-Owned: No
    Listed since: 08-26-2025

  • $35,900
    fair price
    $859 above market
    • 37,522 miles
    • No accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Frontier Motors (422 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pensacola, FL / 422 miles away from Fort Myers, FL

    CERTIFIED: Vehicle comes with remainder of 10 year/ 100k Mile Powertrain Warranty (See dealer for de, APPLE CARPLAY, ANDROID AUTO, Active Parking Assi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA893992
    Stock: 893992
    Certified Pre-Owned: No
    Listed since: 03-03-2025

  • New Listing
    • 53,217 miles
    • No accidents, 2 owners, personal use
    • Mercedes-Benz of Fort Myers (3 mi away)
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    • Upgraded Stereo
    Close

    Located in Fort Myers, FL / 3 miles away from Fort Myers, FL

    This 2019 Mercedes-Benz E-Class 300 comes equipped with Navigation System, Front Collision Mitigation, Back-Up Camera, Power Folding Mirrors, Power Li...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: WDDZF4JB4KA584838
    Stock: MKA584838
    Certified Pre-Owned: No
    Listed since: 08-26-2025

  • Price Drop
    • 759 miles
    • No accidents, 1 owner, personal use only
    • 7 Seats, 22 City / 31 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Los Angeles, CA / 2,218 miles away from Fort Myers, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB6SA120017
    Stock: 2003979720
    Certified Pre-Owned: No
    Listed since: 08-23-2025

  • New Listing
    • 6,016 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 30 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from GA to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Buford, GA / 534 miles away from Fort Myers, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB1MB004086
    Stock: 27513988
    Certified Pre-Owned: No

Showing 253 - 273 out of 1,113 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.2 out of 5 stars32 Reviews
Write a vehicle reviewSee all 32 reviews
  • 5 star
    (63%)
  • 4 star
    (16%)
  • 3 star
    (6%)
  • 2 star
    (6%)
  • 1 star
    (9%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2021 Mercedes-Benz E-Class in Fort Myers, FL Values

Estimated values
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$27,812$29,887$31,980
Clean$27,222$29,201$31,191
Average$26,240$28,058$29,876
Rough$24,963$26,573$28,165

The average list price of a used 2021 Mercedes-Benz E-Class in Fort Myers, Florida is $40,344. The average mileage on a used Mercedes-Benz E-Class 2021 for sale in Fort Myers, Florida is 37,607. Based on the average mileage of 37,607 for used 2021 Mercedes-Benz E-Class for sale in Fort Myers, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2021 in Fort Myers, Florida to be $26,240.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.