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2,472 listings
  • Price Drop
    $36,500
    good price
    $1,975 below market
    • 29,874 miles
    • 1 accident, 2 owners, personal use
    • 23 City / 31 Hwy MPG
    • Adams North Charlotte (87 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Charlotte, NC / 87 miles away from Columbia, SC

    ABOUT THIS VEHICLE * Back-up Camera * Blind Spot Monitor * Bluetooth Connection * Climate Control * Heated Front Seat * Integrated Turn Signal Mirrors...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB3NB071811
    Stock: A3P-71811
    Certified Pre-Owned: No
    Listed since: 04-10-2025

  • Stock photo**
    $22,000
    good price
    $1,480 below market
    • 87,264 miles
    • 1 accident, 3 owners, personal use
    • 22 City / 30 Hwy MPG
    • Capital Subaru of Greensboro (157 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Greensboro, NC / 157 miles away from Columbia, SC

    Capital Subaru of Greensboro is proud to present you with another True Market Priced Pre-Owned Vehicle. This 2020 Mercedes-Benz E-Class E 350 is loade...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB1LA820588
    Stock: 28PN0396
    Certified Pre-Owned: No
    Listed since: 03-19-2025

  • New Listing
    • 14,779 miles
    • No accidents, 2 owners, personal use
    • 21 City / 29 Hwy MPG
    • Mercedes-Benz of Wilmington (495 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Wilmington, DE / 495 miles away from Columbia, SC

    ONE OWNER !! CLEAN CARFAX !! CERTIFIED !! UNLIMITED MILEAGE WARRANTY !! LOADED WITH OPTIONS !! PREMIUM 1 PACAKGE ($2300) - EXTERIOR LIGHTING PACKAGE (...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/29 Highway)

    Listing Information:

    VIN: W1KZF8EB0NB029840
    Stock: 029840
    Certified Pre-Owned: Yes
    Listed since: 05-11-2025

  • Price Drop
    Photos not available
    $43,499
    fair price
    $294 above market
    • 13,390 miles
    • No accidents, 1 owner, personal use
    • 23 City / 31 Hwy MPG
    • Mercedes-Benz of South Orlando (384 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orlando, FL / 384 miles away from Columbia, SC

    CARFAX One-Owner. Cirrus Silver Metallic WE DELIVER TO YOUR HOME OR OFFICE. Active Brake Assist w/Cross-Traffic Function, Active Distance Assist DISTR...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB4NB059442
    Stock: P059442
    Certified Pre-Owned: No
    Listed since: 04-18-2025

  • $44,911
    fair price
    $527 above market
    • 28,780 miles
    • No accidents, 1 owner, personal use
    • 23 City / 30 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Los Angeles, CA / 2,124 miles away from Columbia, SC

    CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Keyless Start,Navigation System,Remote Start,Sunroo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB0NB054319
    Stock: 20794C
    Certified Pre-Owned: No

  • New Listing
    • 16,538 miles
    • Insurance loss reported, 2 owners, personal use
    • 23 City / 31 Hwy MPG
    • World Imports Lotus of Jacksonville (260 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 260 miles away from Columbia, SC

    World Imports USA / Lotus of Jacksonville. Since 1986 we have sold thousands of cars both local and worldwide. Our friendly, no-pressure sales approac...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: Yes

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXNB088833
    Stock: 14408
    Certified Pre-Owned: No
    Listed since: 02-28-2025

  • Price Drop
    $37,722
    fair price
    $204 above market
    • 48,325 miles
    • No accidents, 2 owners, personal use only
    • 23 City / 31 Hwy MPG
    • Deacon Jones Ford of Clinton (166 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Clinton, NC / 166 miles away from Columbia, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXNB030124
    Stock: CG35100A
    Certified Pre-Owned: No
    Listed since: 04-09-2025

  • New Listing
    $27,409
    fair price
    $891 above market
    • 48,855 miles
    • No accidents, 2 owners, personal use
    • 23 City / 32 Hwy MPG
    • AutoNation Honda Clearwater (434 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Clearwater, FL / 434 miles away from Columbia, SC

    Premium PackageBurmester ® Surround Sound SystemAmg ® Line ExteriorSun/MoonroofWheels: 19" Amg ® Twin 5-SpokeNavigation SystemLed Lo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/32 Highway)

    Listing Information:

    VIN: W1KZF8DB7LA845044
    Stock: LA845044
    Certified Pre-Owned: No
    Listed since: 05-09-2025

  • New Listing
    Photos not available
    $48,700
    good price
    $1,301 below market
    • 19,997 miles
    • No accidents, personal use only
    • 23 City / 30 Hwy MPG
    • Alfa Romeo of Tyson's (397 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Vienna, VA / 397 miles away from Columbia, SC

    Clean CARFAX. CARFAX One-Owner. Blue 2022 Mercedes-Benz E-Class E 450 LIKE NEW, DRIVER ASSISTANCE PACKAGE, PANORAMA ROOF, PREMIUM PACKAGE LIGHT, WARMT...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Title information not provided

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB7NB082733
    Stock: 462555A
    Certified Pre-Owned: No
    Listed since: 05-12-2025

  • Price Drop
    $54,779
    fair price
    $2,104 above market
    • 49,661 miles
    • No accidents, 1 owner, personal use
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Gainesville (310 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Gainesville, FL / 310 miles away from Columbia, SC

    Clean CARFAX. CARFAX One-Owner. Active Distance Assist DISTRONIC®, Active Lane Keeping Assist, Active Speed Limit Assist, Active Steering Assist, Burm...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB2RA005965
    Stock: F015087A
    Certified Pre-Owned: Yes
    Listed since: 04-28-2025

  • New Listing
    $35,481
    fair price
    $457 below market
    • 45,689 miles
    • 1 accident, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Arrigo Chrysler Dodge Jeep Ram of Fort Pierce (462 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fort Pierce, FL / 462 miles away from Columbia, SC

    GOTTA GO ARRIGO!!! CALL TODAY BEFORE ITS GONE... 7**-8**-9***!! GREAT FINANCING OPTIONS AVAILABLE!!Certified. Obsidian Black Metallic 2022 Mercedes-Be...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7NB073402
    Stock: B073402
    Certified Pre-Owned: No
    Listed since: 02-28-2025

    • 5,609 miles
    • No accidents, 1 owner, personal use
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Marietta (203 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Marietta, GA / 203 miles away from Columbia, SC

    Burmester ® 4D Surround SoundDual MoonroofNavigation SystemVentilated Front SeatsIlluminated GrilleKeyless StartCooled Front Seat(S)Macchia...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB7RA008523
    Stock: RA008523
    Certified Pre-Owned: Yes
    Listed since: 01-06-2025

    • 7,770 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Baker Motor Company of Charleston (102 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Charleston, SC / 102 miles away from Columbia, SC

    Mercedes-Benz Certified, UNLIMITED MILE WARRANTY! AMG Line Exterior (Perforated Front Brake Discs & Fr Brake Calipers), Night Package, Premium Package...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6NB090997
    Stock: MB5327A
    Certified Pre-Owned: No
    Listed since: 04-30-2025

    • 7,279 miles
    • No accidents, personal use only
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (258 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 258 miles away from Columbia, SC

    This Mercedes-Benz E 350 4MATIC Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HBXRA045212
    Stock: PBL9147
    Certified Pre-Owned: No
    Listed since: 03-19-2025

  • Price Drop
    • 2,103 miles
    • No accidents, 1 owner, personal use
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Arlington (398 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Arlington, VA / 398 miles away from Columbia, SC

    Experience the refined luxury and cutting-edge technology of the white 2024 Mercedes-Benz E-Class E 350 4MATIC Sedan with only 2,103 miles. This stunn...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB7RA029050
    Stock: BA029050
    Certified Pre-Owned: No
    Listed since: 04-25-2025

    • 8,995 miles
    • No accidents, personal use only
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (258 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 258 miles away from Columbia, SC

    This Mercedes-Benz E-Class has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Ante...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB3RA012147
    Stock: PBL9131
    Certified Pre-Owned: No
    Listed since: 03-11-2025

  • Price Drop
    • 12,045 miles
    • No accidents, 1 owner, personal use only
    • 6cyl automatic
    • Mercedes-Benz of Nashville (356 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Franklin, TN / 356 miles away from Columbia, SC

    This CERTIFIED 2022 Mercedes-Benz E-Class E 450 is a One Owner vehicle with a Clean Carfax, Selenite Gray Metallic exterior, and Saddle Brown interior...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1J5JB9NF177297
    Stock: PNF177297
    Certified Pre-Owned: Yes
    Listed since: 04-28-2025

    • 9,967 miles
    • No accidents, personal use only
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (258 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 258 miles away from Columbia, SC

    This Mercedes-Benz E 350 4MATIC Sedan has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Windo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB5RA009928
    Stock: PBL8890
    Certified Pre-Owned: No
    Listed since: 03-04-2024

    • 16,917 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Carvana - Charlotte (83 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Charlotte, NC / 83 miles away from Columbia, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: WDDZF6JB5LA742830
    Stock: 2003658041
    Certified Pre-Owned: No
    Listed since: 04-17-2025

    • 11,608 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 31 Hwy MPG
    • Rick Hendrick Buick GMC (181 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Duluth, GA / 181 miles away from Columbia, SC

    E 350 trim, Graphite Grey Metallic exterior and Macchiato Beige/Black interior. CARFAX 1-Owner, LOW MILES - 11,608! EPA 31 MPG Hwy/23 MPG City! Heated...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB7NB056728
    Stock: S12810A
    Certified Pre-Owned: No
    Listed since: 02-24-2025

    • 12,183 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • RBM of Atlanta (195 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Atlanta, GA / 195 miles away from Columbia, SC

    CERTIFIED, ONE OWNER, CLEAN CARFAX! WHEELS: 19 AMG TWIN 5-SPOKE (RZI) -inc: Tires: 245/40R19 Front & 275/35R19 Rear, NATURAL GRAIN BLACK ASH WOOD TRIM...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1K1K5JB6NF177089
    Stock: U21273
    Certified Pre-Owned: Yes
    Listed since: 11-08-2024

Showing 232 - 252 out of 2,472 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.3 out of 5 stars38 Reviews
Write a vehicle reviewSee all 38 reviews
  • 5 star
    (66%)
  • 4 star
    (21%)
  • 3 star
    (3%)
  • 2 star
    (3%)
  • 1 star
    (8%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2022 Mercedes-Benz E-Class in Columbia, SC Values

Estimated values
2022 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$35,084$37,483$39,997
Clean$34,473$36,753$39,135
Average$33,456$35,535$37,698
Rough$32,133$33,951$35,829

The average list price of a used 2022 Mercedes-Benz E-Class in Columbia, South Carolina is $50,386. The average mileage on a used Mercedes-Benz E-Class 2022 for sale in Columbia, South Carolina is 23,697. Based on the average mileage of 23,697 for used 2022 Mercedes-Benz E-Class for sale in Columbia, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2022 in Columbia, South Carolina to be $33,456.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.