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2,324 listings
  • $27,163
    great price
    $6,335 below market
    • 43,952 miles
    • 2 accidents, 2 owners, corporate fleet vehicle
    • 22 City / 30 Hwy MPG
    • Carget Motors (430 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Woodbridge, VA / 430 miles away from Charleston, SC

    The 2021 Mercedes-Benz E350 is a paragon of sophistication and performance in the luxury sedan segment. Powered by a turbocharged 2.0-liter four-cylin...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB7MA905081
    Stock: 905081
    Certified Pre-Owned: No
    Listed since: 12-13-2024

  • $36,981
    great price
    $4,203 below market
    • 36,179 miles
    • No accidents, 1 owner, personal use only
    • 23 City / 30 Hwy MPG
    • Audi Melbourne (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in West Melbourne, FL / 329 miles away from Charleston, SC

    Vehicle Offered at Audi Melbourne's NEW Location conveniently located just off I-95 EXIT 180 in Melbourne,Fl. 321-339-5500.Recent Arrival! CARFAX One-...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1KZF5KB8MA894787
    Stock: A894787
    Certified Pre-Owned: No
    Listed since: 06-05-2025

  • $26,888
    great price
    $3,745 below market
    • 59,914 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 22 City / 31 Hwy MPG
    • Gulf Coast Auto Brokers of Sarasota (411 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 411 miles away from Charleston, SC

    Thank you for visiting another one of Gulf Coast Auto Brokers Inc's online listings! Please continue for more information on this 2021 Mercedes-Benz E...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MB002459
    Stock: 2459
    Certified Pre-Owned: No
    Listed since: 02-19-2025

  • $30,750
    great price
    $3,893 below market
    • 39,039 miles
    • 1 accident, 2 owners, personal use only
    • 22 City / 31 Hwy MPG
    • Greenway Chrysler Dodge Jeep Ram (302 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orlando, FL / 302 miles away from Charleston, SC

    LEATHER, NAVIGATION, PANORAMA ROOF, Active Brake Assist w/Cross-Traffic Function, Active Distance Assist DISTRONIC®, Active Lane Change Assist, Active...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB2MA918709
    Stock: MA918709
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • $30,985
    great price
    $2,952 below market
    • 24,694 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 31 Hwy MPG
    • AutoNation Chevrolet Pembroke Pines (470 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pembroke Pines, FL / 470 miles away from Charleston, SC

    The following items have been reconditioned on this vehicle: all new tires! Premium PackageAmg ® Line ExteriorLunar Blue MetallicSun/Moonroo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB4MA967782
    Stock: MA967782
    Certified Pre-Owned: No
    Listed since: 04-09-2025

  • Price Drop
    $31,900
    good price
    $3,019 below market
    • 22,032 miles
    • 1 accident, 1 owner, personal use
    • 22 City / 31 Hwy MPG
    • Mullinax Ford of Palm Beach (414 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Lake Park, FL / 414 miles away from Charleston, SC

    Blue Certified 2021 Mercedes-Benz E-Class E 350, Local Trade, Loaded with Leather Seats, Navigation, Rear Camera, Bluetooth, Dual Zone Climate Control...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA909353
    Stock: 909353
    Certified Pre-Owned: No
    Listed since: 06-19-2025

  • $30,920
    good price
    $2,252 below market
    • 59,978 miles
    • No accidents, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • ALM Hyundai West (278 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Lithia Springs, GA / 278 miles away from Charleston, SC

    2021 Mercedes-Benz E 350 4MATIC AWD | Navigation | Apple CarPlay | Priced Below KBBLocation: ALM Ford Marietta 869 Cobb Parkway, Marietta, GA 30060...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB1MA883224
    Stock: SH032931A
    Certified Pre-Owned: No
    Listed since: 06-23-2025

  • $41,498
    fair price
    $772 below market
    • 23,023 miles
    • No accidents, 1 owner, personal use
    • 6cyl automatic
    • AutoNation Chevrolet Greenacres (427 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Greenacres, FL / 427 miles away from Charleston, SC

    Amg ® LineDriver Assistance PackageHead-Up DisplayExterior Lighting PackageGraphite Grey MetallicPanoramic RoofLeather SeatsNavigation Syst...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (23 City/31 Highway)

    Listing Information:

    VIN: W1K1J5JB1MF164266
    Stock: MF164266
    Certified Pre-Owned: No
    Listed since: 06-28-2025

  • Price Drop
    $32,306
    good price
    $2,843 below market
    • 48,302 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 22 City / 30 Hwy MPG
    • Monroe Nissan (161 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Monroe, NC / 161 miles away from Charleston, SC

    Black 2021 Mercedes-Benz E-Class E 350 4MATIC® 4MATIC® 9-Speed Automatic I4***THIS VEHICLE INCLUDES THE FOLLOWING FEATURES AND OPTIONS: Memory Packa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB2MA929255
    Stock: P3745
    Certified Pre-Owned: No
    Listed since: 07-17-2025

  • New Listing
    $33,590
    fair price
    $787 below market
    • 41,960 miles
    • No accidents, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • Carvana - Jacksonville (198 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 198 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB9MA890468
    Stock: 2003842190
    Certified Pre-Owned: No
    Listed since: 06-27-2025

  • Price Drop
    $28,363
    fair price
    $1,027 below market
    • 54,393 miles
    • No accidents, 2 owners, personal use
    • 22 City / 31 Hwy MPG
    • Village Toyota of Homosassa (316 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Homosassa, FL / 316 miles away from Charleston, SC

    2021 Mercedes-Benz E-Class E 350GOOD TIRES, GOOD BRAKES, Active Parking Assist, Burmester® Surround Sound System, Memory Package w/Power Steering Col...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DB6MA960915
    Stock: MA960915A
    Certified Pre-Owned: No
    Listed since: 06-28-2025

    • 64,547 miles
    • No accidents, 1 owner, personal use only
    • 7 Seats, 22 City / 28 Hwy MPG
    • Mercedes-Benz of Delray (439 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Delray Beach, FL / 439 miles away from Charleston, SC

    The following items have been reconditioned on this vehicle: new pair of tires! Premium PackagePanorama SunroofGraphite Grey MetallicPanoramic R...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (22 City/28 Highway)

    Listing Information:

    VIN: W1KZH6AB6MA955328
    Stock: MA955328
    Certified Pre-Owned: No
    Listed since: 03-26-2025

  • Price Drop
    $36,997
    good price
    $2,387 below market
    • 24,052 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Ourisman Lexus of Rockville (463 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Rockville, MD / 463 miles away from Charleston, SC

    ONE OWNER, PREMIUM PKG, NAVIGATION, APPLE CAR PLAY/ANDROID AUTO, HEATED AND VENTILATED SEATS, MOONROOF, 18 ALLOY WHEELS, DYNAMIC RADAR CRUISE CONTROL,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB0MB000403
    Stock: TB000403
    Certified Pre-Owned: No
    Listed since: 07-07-2025

  • Price Drop
    $29,500
    good price
    $2,512 below market
    • 67,391 miles
    • No accidents, 2 owners, personal use
    • 22 City / 30 Hwy MPG
    • Sawgrass INFINITI (457 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Tamarac, FL / 457 miles away from Charleston, SC

    Recent Arrival! 2021 Mercedes-Benz E-Class E 350 White **ANDROID AUTO**, **APPLE CAR PLAY**, **BACKUP CAMERA**, **BLUETOOTH**, **NAVIGATION**, 4MATIC®...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB3MA929961
    Stock: P18474
    Certified Pre-Owned: No
    Listed since: 07-23-2025

  • $53,818
    fair price
    $721 below market
    • 9,459 miles
    • No accidents, 2 owners, personal use only
    • 6cyl automatic
    • Lindsay Volkswagen of Manassas (436 mi away)
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Manassas, VA / 436 miles away from Charleston, SC

    EXTERIOR LIGHTING PACKAGE!!, AMG LINE PACKAGE!!, VENTILATED SEATS!!, HEAD UP DISPLAY!!, ACTUAL MILES!!, E-Class E 450, 2D Convertible, 3.0L I6 Turbo, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (23 City/30 Highway)

    Listing Information:

    VIN: W1K1K5JB5MF164087
    Stock: VP14799
    Certified Pre-Owned: No
    Listed since: 07-03-2025

  • Stock photo**
    $49,500
    good price
    $3,067 below market
    • 34,985 miles
    • No accidents, 1 owner, personal use
    • 22 City / 29 Hwy MPG
    • Lindsay Cadillac of Alexandria (445 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Alexandria, VA / 445 miles away from Charleston, SC

    BUY ONLINE-TEXT-EMAIL-CHAT-PHONE AND WE WILL DELIVER YOUR NEXT VEHICLE TO YOUR DOOR! Priced below KBB Fair Purchase Price! 2021 Mercedes-Benz E-Class ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: W1KZF6BB2MA840410
    Stock: C17923A
    Certified Pre-Owned: No
    Listed since: 07-14-2025

  • $25,222
    good price
    $897 below market
    • 83,494 miles
    • No accidents, 1 owner, personal use
    • 22 City / 30 Hwy MPG
    • Carget Motors (430 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Woodbridge, VA / 430 miles away from Charleston, SC

    The 2021 Mercedes-Benz E 350 exemplifies modern luxury and intelligent design, offering a driving experience that s both refined and engaging. Powered...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB8MA966973
    Stock: 966973
    Certified Pre-Owned: No
    Listed since: 07-11-2025

  • $57,995
    great price
    $4,979 below market
    • 82,254 miles
    • No accidents, 1 owner, personal use only
    • 16 City / 23 Hwy MPG
    • TLEE Auto Brokers (253 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Duluth, GA / 253 miles away from Charleston, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    18 Combined MPG (16 City/23 Highway)

    Listing Information:

    VIN: W1KZF8KB1MA931678
    Stock: 931678
    Certified Pre-Owned: No

  • Price Drop
    $31,889
    fair price
    $351 below market
    • 43,624 miles
    • 1 accident, 2 owners, corporate fleet vehicle
    • 22 City / 31 Hwy MPG
    • Southeast Auto Direct (493 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Iuka, MS / 493 miles away from Charleston, SC

    THE LOWEST PRICED IN 150 MILES!! BACKUP CAMERA, BLUETOOTH, NAVIGATION SYSTEM GPS NAV, SUNROOF/MOONROOF, GOOGLE ANDROID AUTO, APPLE CARPLAY, POWER PAC...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA887130
    Stock: 7K2736PA
    Certified Pre-Owned: No
    Listed since: 06-19-2025

  • $38,990
    fair price
    $786 below market
    • 31,064 miles
    • No accidents, 1 owner, personal use only
    • 22 City / 30 Hwy MPG
    • Carvana - Birmingham (400 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Birmingham, AL / 400 miles away from Charleston, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/30 Highway)

    Listing Information:

    VIN: W1KZF8EB9MA962723
    Stock: 2003883337
    Certified Pre-Owned: No
    Listed since: 07-29-2025

  • New Listing
    $34,998
    good price
    $2,194 below market
    • 44,273 miles
    • 22 City / 31 Hwy MPG
    • CarMax Town Center (280 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Kennesaw, GA / 280 miles away from Charleston, SC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KZF8DBXMA972310
    Stock: 27187355
    Certified Pre-Owned: No

Showing 1 - 21 out of 2,324 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.5 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (73%)
  • 4 star
    (21%)
  • 3 star
    (0%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

New 2021 E-Class with MBUX is a Great Car

gldman, 12/14/2020
2021 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo 9A)
I drove the competitors BMW 5, Audi 6, Lexus ES 350 and this new E Class is really something special. I had the other cars via a Subscription Model including the 2020 Mercedes so I have recent experience for weeks at a time driving the cars. The MBUX is a great user experience. Buy the Premium package because of the 360 camera and the upgraded audio system. The other add-on stuff is … fun but not really needed. You will use Android Auto and not the Mercedes Navi if you want accurate directions. The Mercedes Navi is very pretty but useless for directions. The Augmented Reality is fun, once, and may impress your friends but is more of a distraction than a help. The Driver Assistance package is interesting but the distronic cruise control is the only thing you will actually use from this package. This is a truly comfortable car with the latest electronics. Note if you never have had a Mercedes you will need a good independent mechanic to do your A/B Services (Oil Changes) if you want to avoid the the dealer. You must log all service in the electronic service log which all of the good independent shops will do. Note the Lexus is the best value if not boring, with regular gas and standard oil changes, but I think with the 2021 updates the Mercedes E 350 is more fun than the Audi 6 (watch for recalls) or BMW 5 (needs updating to stay competitive). Obviously you should compare similar versions of each model. Update 2 years later: Well the car is still great. I only have 7,350 miles and just dropped the car for a B Service. So far no problems except for a few early glitches with the cameras that resolved after a restart, Note the dealer costs for A & especially B Service is nuts. I was quoted $1,529.74 for a B Service at the dealer. I am trying a local specialty place that charges $450. I guess I will see. Last year another specialty shop charged $250 for an A service which was fine compared to $595 at the dealer.
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Used 2021 Mercedes-Benz E-Class in Charleston, SC Values

Estimated values
2021 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo 9A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$27,365$30,136$32,933
Clean$26,785$29,444$32,120
Average$25,819$28,292$30,765
Rough$24,562$26,794$29,004

The average list price of a used 2021 Mercedes-Benz E-Class in Charleston, South Carolina is $35,508. The average mileage on a used Mercedes-Benz E-Class 2021 for sale in Charleston, South Carolina is 44,696. Based on the average mileage of 44,696 for used 2021 Mercedes-Benz E-Class for sale in Charleston, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Mercedes-Benz E-Class 2021 in Charleston, South Carolina to be $25,819.

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