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218 listings
    • 45,907 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Smart Lexus (156 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Davenport, IA / 156 miles away from Des Moines, IA

    Certified. Caviar 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V For more info. please call TJ Deere Manager 5**-4**-4***, 3.5L V6 DOHC VVT-i 24V,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC086198
    Stock: L1N086198
    Certified Pre-Owned: No
    Listed since: 01-23-2025

  • Stock photo**
    • 136,108 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Walser Auto Campus (331 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Wichita, KS / 331 miles away from Des Moines, IA

    2010 Lexus RX 450h, located at Mercedes-Benz of Wichita. Original MSRP $53,054. Smoky Granite Mica with Black Leather interior. This local 1 owner RX ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA1A2006842
    Stock: 57M1208T
    Certified Pre-Owned: No
    Listed since: 05-26-2025

  • New Listing
    • 40,079 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NC to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Raleigh, NC / 891 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC077569
    Stock: 26262259
    Certified Pre-Owned: No

  • New Listing
    • 165,757 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Chicago Car Company (282 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Naperville, IL / 282 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA1C2425485
    Stock: 422585
    Certified Pre-Owned: No

  • New Listing
    • 17,667 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Victorville, CA / 1,375 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC094339
    Stock: 27492986
    Certified Pre-Owned: No

    • 27,216 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Willis Lexus (8 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Des Moines, IA / 8 miles away from Des Moines, IA

    AWD, ONE OWNER, WELL MAINTAINED VEHICLE-Apple CarPlay/Android Auto.-Exterior Parking Camera Rear.--Heated / Ventilated Front Seats.-Heated Leather Ste...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC082334
    Stock: LX5547
    Certified Pre-Owned: Yes
    Listed since: 04-19-2025

  • Stock photo**
    • 68,345 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tom Roush Lincoln (412 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fishers, IN / 412 miles away from Des Moines, IA

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V**ONE OWNER**, **NO ACCIDENTS**, **LEATHER SEATS**, **PANORAMIC SUNROOF/MOONROOF**...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC083161
    Stock: L25096A
    Certified Pre-Owned: No
    Listed since: 05-31-2025

  • New Listing
    • 185,273 miles
    • 5 Seats, 32 City / 28 Hwy MPG
    • Highend Motors (299 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    • Auto Climate Control
    Close

    Located in Chicago, IL / 299 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (32 City/28 Highway)

    Listing Information:

    VIN: JTJZB1BA2C2006384
    Stock: M1038
    Certified Pre-Owned: No
    Listed since: 06-08-2025

  • $8,950
    great price
    $1,603 below market
    • 180,592 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 30 City / 28 Hwy MPG
    • Zone Motors (289 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Addison, IL / 289 miles away from Des Moines, IA

    BUY WITH CONFIDENCE! CARFAX Buyback Guarantee qualified! LOADED WITH VALUE! Comes equipped with: Air Conditioning, Sunroof, MP3, Bluetooth, Navigation...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BAXB2045141
    Stock: 045141
    Certified Pre-Owned: No
    Listed since: 03-23-2025

  • New Listing
    $12,900
    good price
    $1,605 below market
    • 93,873 miles
    • No accidents, 3 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Newark Rides (260 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Newark, IL / 260 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA6B2422774
    Stock: 104424
    Certified Pre-Owned: No
    Listed since: 05-25-2025

  • New Listing
    $8,990
    good price
    $1,197 below market
    • 188,638 miles
    • 5 Seats, 30 City / 28 Hwy MPG
    • NB Motors (279 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Naperville, IL / 279 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA2B2419368
    Stock: 501
    Certified Pre-Owned: No
    Listed since: 06-08-2025

  • $10,995
    fair price
    $204 below market
    • 166,416 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 30 City / 28 Hwy MPG
    • United Auto Sales (473 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Oklahoma, OK / 473 miles away from Des Moines, IA

    MUST SEE LEXUS WELL KEPT GOOD CONDITION!!! Come in today to take a look and a test drive. Now we have 2 locations. Please call 4**-7**-4*** if you hav...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA6B2044567
    Stock: 044567
    Certified Pre-Owned: No
    Listed since: 12-31-2024

    • 144,515 miles
    • No accidents, 4 owners, personal use
    • 5 Seats, 30 City / 28 Hwy MPG
    • C&S Car Company II (89 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Waterloo, IA / 89 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA4B2417329
    Stock: FSB11573C
    Certified Pre-Owned: No
    Listed since: 04-03-2025

  • Price Drop
    • 50,100 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 32 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    • Auto Climate Control
    Close

    Located in Tampa, FL / 1,133 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (32 City/28 Highway)

    Listing Information:

    VIN: JTJZB1BA0B2404689
    Stock: 2003736671
    Certified Pre-Owned: No
    Listed since: 05-14-2025

    • 104,500 miles
    • Insurance loss reported, 2 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Elite Motors (125 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Bellevue, NE / 125 miles away from Des Moines, IA

    2011 RX450h AWD 104k miles, Contact us to schedule a test drive and experience the luxury and capability of this Lexus "If you're interested in learni...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA1B2037042
    Stock: 037042
    Certified Pre-Owned: No
    Listed since: 04-19-2025

  • $8,000
    great price
    $1,498 below market
    • 174,954 miles
    • No accidents, 3 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Plainfield Motors (279 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Plainfield, IL / 279 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA3A2011668
    Stock: 011668
    Certified Pre-Owned: No
    Listed since: 01-06-2025

  • New Listing
    $10,900
    great price
    $2,086 below market
    • 101,686 miles
    • 1 accident, 3 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Newark Rides (260 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Newark, IL / 260 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA8A2011892
    Stock: 104423
    Certified Pre-Owned: No
    Listed since: 05-11-2025

  • $6,980
    good price
    $1,116 below market
    • 194,395 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • KD Motorsport (289 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Palatine, IL / 289 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BAXA2412246
    Stock: 101247
    Certified Pre-Owned: No

  • $10,999
    fair price
    $262 below market
    • 146,537 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • I-80 Auto Sales (305 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Hazel Crest, IL / 305 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA4A2007306
    Stock: 007306
    Certified Pre-Owned: No

  • $12,899
    fair price
    $617 below market
    • 99,879 miles
    • 1 accident, 5 owners, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • J Prime Auto Sales (238 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Loretto, MN / 238 miles away from Des Moines, IA

    2010 LEXUS RX 450 HYBRID AWD WITH BACK UP CAMERA, NAVIGATION SYSTEMS, BLUETOOTH HAND FREE, SUNROOF, RUNS AND DRIVES SMOOTHLY WELL WITH LEATHER SEATS, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA8A2022231
    Stock: 022231
    Certified Pre-Owned: No
    Listed since: 10-31-2024

  • $12,977
    fair price
    $875 below market
    • 89,379 miles
    • 3 accidents, 4 owners, personal use
    • 5 Seats, 30 City / 28 Hwy MPG
    • Castle Motors (297 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • Multi-Zone Climate C...
    Close

    Located in Brookfield, IL / 297 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    29 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: JTJBC1BA0A2410912
    Stock: 10414
    Certified Pre-Owned: No
    Listed since: 04-09-2025

Showing 190 - 210 out of 218 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.5 out of 5 stars38 Reviews
Write a vehicle reviewSee all 38 reviews
  • 5 star
    (71%)
  • 4 star
    (13%)
  • 3 star
    (11%)
  • 2 star
    (3%)
  • 1 star
    (3%)
5 out of 5 stars

Lexus RX 450 > 350

TW, 01/13/2018
2017 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I spent a lot of time shopping for my new car and ended up buying the Lexus RX 450h. Before settling on the RX 450h I drove many of the competing vehicles including Audi SQ5, Q7, Mercedes GLC AMG, GLE, Volvo XC60 and XC90. I also drove the Lexus RX 350 as well. Initially I wasn't looking for a hybrid but I am glad I drove the 450h and ended up buying it. I've driven other hybrids as … rental cars over the years (Prius and Ford Fusion) and in most cases the switch between electric and gas isn't particularly smooth, not so in the RX. Other than hearing the gas engine, it's just continuous power and smoothly switches over. The CVT makes the vehicle incredibly smooth as well with no gear changes. For the 2017s, the hybrid carries a pretty big premium for the base vehicle but upon closer inspection, it comes with a lot of standard features and in the end it really only adds about $1800 to the price of the vehicle. For 2018, the hybrid packaging is different and now has the same features as the base 350. The premium is now only about $1000. For that you get, in my opinion a much smoother vehicle and much better gas mileage. Bottom line, even if you aren't interested in the hybrid for environmental reasons, I still think it is a better vehicle and worth the upgrade costs. To address one common complaint, the weakest part of the RX vehicles is the user interface for the entertainment/navigation system. The remote touch control isn't as convenient as some other systems but it is more than adequate. Some times the user interface is a bit more complex than needed. That said, you will get used to it and don't let that turn you off from a great vehicle. Bottom line, if you are going to test drive RXs, take an RX 450h for a spin. I think you will like it.
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Used 2022 Lexus RX 450h in Des Moines, IA Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$23,599$24,549$25,539
Clean$23,285$24,209$25,172
Average$22,761$23,642$24,560
Rough$22,079$22,906$23,764

The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $20,964. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 115,325. Based on the average mileage of 115,325 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $22,761.

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