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    • 25,102 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Kings Toyota (423 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cincinnati, OH / 423 miles away from Tupelo, MS

    Odometer is 1187 miles below market average! 20/28 City/Highway MPG Iridium 2022 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24N5049297
    Stock: N5049297
    Certified Pre-Owned: No
    Listed since: 05-01-2025

  • New Listing
    $33,998
    fair price
    $823 above market
    • 46,570 miles
    • 2 accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NY to MS*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Smithtown, NY / 963 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E29L5018264
    Stock: 27378811
    Certified Pre-Owned: No

    • 64,174 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 20 City / 28 Hwy MPG
    • Fred Haas Toyota Country (499 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Houston, TX / 499 miles away from Tupelo, MS

    Caviar 2022 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V ***ONE OWNER***, ***WELL MAINTAINED***, ***Navigation***, ***Leathe...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHSZ1B22N5050751
    Stock: 5050751A
    Certified Pre-Owned: No
    Listed since: 05-07-2025

  • New Listing
    • 74,041 miles
    • No accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • Hendrick Lexus Northlake (453 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Charlotte, NC / 453 miles away from Tupelo, MS

    Heated/Cooled Seats, Moonroof, Aluminum Wheels, Fog Lamps, Lane Keeping Assist, Keyless Start, Back-Up Camera, All Wheel Drive. SHOP WITH CONFIDENCE16...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E26L5017475
    Stock: S28788AA
    Certified Pre-Owned: No
    Listed since: 05-14-2025

    • 51,358 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • McDonough Hyundai (266 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in McDonough, GA / 266 miles away from Tupelo, MS

    Clean CARFAX. CARFAX One-Owner. Visit the ALL-NEW MCDONOUGH HYUNDAI. No hidden fees, no gimmicks. Real Prices, Great value. ALL used vehicles are full...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24N5053379
    Stock: T053379
    Certified Pre-Owned: No
    Listed since: 04-28-2025

  • Price Drop
    $46,162
    great price
    $4,266 below market
    • 15,499 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Jim Hudson Lexus (442 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Columbia, SC / 442 miles away from Tupelo, MS

    L/Certified Details: * Warranty Deductible: $0 * Limited Warranty: 24 Month/Unlimited Mile * 161 Point Inspection * Roadside Assistance * Vehicle Hist...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26P5070767
    Stock: LC9797
    Certified Pre-Owned: Yes
    Listed since: 04-21-2025

  • $45,738
    great price
    $4,904 below market
    • 20,566 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Jim Hudson Lexus of Augusta (384 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Augusta, GA / 384 miles away from Tupelo, MS

    L/Certified Details: * Limited Warranty: 24 Month/Unlimited Mile * Warranty Deductible: $0 * 161 Point Inspection * Vehicle History * Roadside Assista...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26M5037148
    Stock: LK8508A
    Certified Pre-Owned: Yes
    Listed since: 05-01-2025

  • New Listing
    $38,252
    great price
    $6,864 below market
    • 32,544 miles
    • No accidents, 3 owners, personal use
    • 20 City / 28 Hwy MPG
    • Audi Northlake (452 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Charlotte, NC / 452 miles away from Tupelo, MS

    CARFAX 1-Owner, LOW MILES - 32,544! PRICE DROP FROM $39,999, FUEL EFFICIENT 28 MPG Hwy/20 MPG City! Heated/Cooled Seats, Sunroof, Navigation, Satellit...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B25M5039733
    Stock: SA22704A
    Certified Pre-Owned: No
    Listed since: 02-25-2025

  • New Listing
    • 121,711 miles
    • 1 accident, 3 owners, personal use only
    • 18 City / 26 Hwy MPG
    • Mars Dealership (473 mi away)
    • AWD/4WD
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 473 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (18 City/26 Highway)

    Listing Information:

    VIN: JTHCE5C26C5002429
    Stock: 2503-02429
    Certified Pre-Owned: No

    • 44,482 miles
    • No accidents, 3 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Northside Lexus (487 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Spring, TX / 487 miles away from Tupelo, MS

    F-SPORT PACKAGE! This Lexus IS 350 comes generously equipped with: FSPORT Package, Blind Sport Monitors, Navigation with Backup Camera, and much more!...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29M5047642
    Stock: L30451A
    Certified Pre-Owned: No
    Listed since: 04-16-2025

  • New Listing
    $39,416
    great price
    $5,816 below market
    • 33,623 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Toyota South Atlanta (254 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Morrow, GA / 254 miles away from Tupelo, MS

    Flare Red w/Ginsumi w/F SPORT NuLuxe Seat Trim, Adaptive Variable Suspension, Card Key, Dynamic Handling Package, Navigation Package w/Mark Levinson A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24M5046124
    Stock: M5046124
    Certified Pre-Owned: No
    Listed since: 05-12-2025

  • $39,998
    great price
    $4,665 below market
    • 34,181 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Cadillac of South Charlotte (448 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pineville, NC / 448 miles away from Tupelo, MS

    This 2021 Lexus IS 350 F SPORT featuring Blind Spot Monitor, Cross-Traffic Alert, Lane Departure Warning, Front Collision Mitigation, Back-Up Camera, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B20M5045195
    Stock: TM5045195
    Certified Pre-Owned: No
    Listed since: 04-17-2025

    • 53,272 miles
    • 1 accident, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Caldwell Toyota (218 mi away)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Conway, AR / 218 miles away from Tupelo, MS

    OPEN NOW! TO KEEP YOU SAFE, DIGITAL ONLINE BUYING EXPERIENCE AVAILABLEBUY ONLINE-TEXT-EMAIL-CHAT-PHONEFROM OUR SALES FLOOR TO YOUR DOOR!IT'S THAT EASY...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B22N5051436
    Stock: 250662A
    Certified Pre-Owned: No
    Listed since: 05-03-2025

  • $40,998
    great price
    $5,052 below market
    • 41,481 miles
    • 1 accident, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Price LeBlanc Lexus (302 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Baton Rouge, LA / 302 miles away from Tupelo, MS

    L/CERTIFIEDThe 2021 Lexus IS 350 F SPORT in Atomic Silver with a unique Black with Ginsumi interior is a striking, performance-focused luxury sedan. T...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21M5041141
    Stock: LE041141
    Certified Pre-Owned: Yes
    Listed since: 05-08-2025

  • $40,444
    good price
    $1,887 below market
    • 30,056 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Subaru of Kennesaw (236 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Kennesaw, GA / 236 miles away from Tupelo, MS

    CARFAX One-Owner. Clean CARFAX. Silver 2023 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V New Feature, IS 350 F SPORT, 4D Sed...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B25P5063955
    Stock: K26463B
    Certified Pre-Owned: No
    Listed since: 04-03-2025

  • $34,995
    great price
    $2,616 below market
    • 65,198 miles
    • 1 accident, 1 owner, personal use
    • 19 City / 26 Hwy MPG
    • Steve White Volvo (364 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Greenville, SC / 364 miles away from Tupelo, MS

    Call 8**-2**-1*** and ask for Audi sales for more info! *All prices exclude IMF, applicable taxes, tag, title, registration and $499 closing fees. We ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E24M5020487
    Stock: PA8516
    Certified Pre-Owned: No
    Listed since: 03-29-2025

    • 19,370 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Park Place Lexus Plano (475 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Plano, TX / 475 miles away from Tupelo, MS

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21P5058736
    Stock: PLD252224A
    Certified Pre-Owned: Yes
    Listed since: 04-25-2025

    • 38,426 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Fred Haas Toyota Country (499 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Houston, TX / 499 miles away from Tupelo, MS

    Ultra White 2023 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V ***CLEAN CARFAX HISTORY***, ***WELL MAINTAINED***, ***Navigati...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B27P5060023
    Stock: 5060023A
    Certified Pre-Owned: No
    Listed since: 04-10-2025

  • Price Drop
    $42,990
    fair price
    $825 below market
    • 32,676 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Butler Lexus of South Atlanta (245 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Union City, GA / 245 miles away from Tupelo, MS

    **OEM CERTIFIED** Thank you for choosing BUTLER LEXUS OF SOUTH ATLANTA, this Cloudburst Gray 2023 Lexus IS 350 F SPORT is a great choice! Check out th...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24P5064465
    Stock: 5133635A
    Certified Pre-Owned: Yes
    Listed since: 04-02-2025

    • 18,169 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Wells Auto Group (462 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Mckinney, TX / 462 miles away from Tupelo, MS

    2023 Lexus IS 350 F SPORT Black w/Perforated NuLuxe Seat Trim (EA), Navigation System. CARFAX One-Owner. Clean CARFAX. Odometer is 5395 miles below ma...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29P5066096
    Stock: P5066096
    Certified Pre-Owned: No
    Listed since: 03-25-2025

    • 22,528 miles
    • No accidents, 1 owner, personal use only
    • 19 City / 26 Hwy MPG
    • BMW of Dallas (478 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Dallas, TX / 478 miles away from Tupelo, MS

    Navigation Package W/Mark Levinson AudioWheels: 19" Matte Black Bbs ForgedIntuitive Park Assist W/Rctb & PvmTriple-Beam HeadlampsMoonroofHandling...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E21P5028258
    Stock: P5028258
    Certified Pre-Owned: No
    Listed since: 05-09-2025

Showing 106 - 126 out of 319 listings

Consumer Reviews for the Lexus IS 350

Read recent reviews for the Lexus IS 350
Overall Consumer Rating
4.5 out of 5 stars27 Reviews
Write a vehicle reviewSee all 27 reviews
  • 5 star
    (70%)
  • 4 star
    (19%)
  • 3 star
    (4%)
  • 2 star
    (4%)
  • 1 star
    (4%)
5 out of 5 stars

2016 IS350 F Sport

Tim, 03/30/2016
2016 Lexus IS 350 4dr Sedan AWD (3.5L 6cyl 6A)
I hesitated to buy this car because of Consumer Reports rating. They did not like the car very much. Later I found their review was based on the entry level IS. My opinion is that this car is awesome. I have owned over fifty cars in my life. I am hard to please. This car accomplishes what it is supposed to do. When you factor in reliability it wins the class with little competition.
Report abuse

Used 2022 Lexus IS 350 in Tupelo, MS Values

Estimated values
2022 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$30,276$31,708$33,204
Clean$29,769$31,142$32,573
Average$28,925$30,198$31,523
Rough$27,828$28,971$30,157

The average list price of a used 2022 Lexus IS 350 in Tupelo, Mississippi is $39,467. The average mileage on a used Lexus IS 350 2022 for sale in Tupelo, Mississippi is 42,144. Based on the average mileage of 42,144 for used 2022 Lexus IS 350 for sale in Tupelo, MS and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2022 in Tupelo, Mississippi to be $28,925.

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