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346 listings
  • $40,420
    fair price
    $1,127 above market
    • 36,555 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • ALM Kennesaw (235 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Kennesaw, GA / 235 miles away from Tupelo, MS

    HEATED SEATS..BACKUP CAMERA..POWER SEATS..SMART DEVICE INTEGRATION..BLUETOOTH..KEYLESS ENTRY..FULLY LOADED OPTIONS HEAT REAR DEFROST PWR WINDOWS PWR L...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24N5054824
    Stock: LF714276A
    Certified Pre-Owned: No
    Listed since: 07-02-2025

  • New Listing
    • 87,633 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • EchoPark Automotive Houston (North Freeway) (498 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Houston, TX / 498 miles away from Tupelo, MS

    At EchoPark, it’s all about offering you options for a happy experience. We have thousands of new-to-you makes and models that range from sedans to tr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29N5056259
    Stock: CN5056259
    Certified Pre-Owned: No
    Listed since: 07-18-2025

  • New Listing
    $32,990
    fair price
    $1,113 above market
    • 56,960 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Phoenix, AZ / 1,338 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21L5036441
    Stock: 2003901528
    Certified Pre-Owned: No
    Listed since: 07-17-2025

  • $43,998
    fair price
    $175 above market
    • 17,512 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 20 City / 28 Hwy MPG
    • CarMax Huntsville (118 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Huntsville, AL / 118 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B27N5054512
    Stock: 27322634
    Certified Pre-Owned: No

  • New Listing
    $30,998
    fair price
    $1,107 above market
    • 78,022 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from FL to MS*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Orlando, FL / 592 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28L5037022
    Stock: 27608082
    Certified Pre-Owned: No

  • Price Drop
    $43,258
    great price
    $4,419 below market
    • 11,975 miles
    • No accidents, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Hampton Hyundai (293 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Fort Walton Beach, FL / 293 miles away from Tupelo, MS

    Clean CARFAX. Black Artificial Leather. Priced below KBB Fair Purchase Price!Hampton Has it! Hampton's Hot!** MAY REQUIRE FINANCING THROUGH DEALE...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24P5070119
    Stock: 3W10722
    Certified Pre-Owned: No
    Listed since: 06-17-2025

  • Stock photo**
    $47,998
    fair price
    $1,059 above market
    • 26,271 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (487 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 487 miles away from Tupelo, MS

    You won't want to miss this excellent value! Comprehensive style mixed with all around versatility makes it an outstanding performance sedan! Lexus pr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B22N5055972
    Stock: 39174A
    Certified Pre-Owned: Yes
    Listed since: 07-17-2025

  • New Listing
    • 2,967 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • CarMax Columbia (431 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Columbia, SC / 431 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26N5053447
    Stock: 26667289
    Certified Pre-Owned: No

    • 18,684 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Ewing Subaru of Plano (477 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Plano, TX / 477 miles away from Tupelo, MS

    2022 Lexus IS 350 F SPORT Black w/Black w/NuLuxe Seat Trim, 10 Speakers, Alloy wheels, Apple CarPlay/Android Auto, Exterior Parking Camera Rear, Lexus...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B27N5054851
    Stock: N5054851
    Certified Pre-Owned: No
    Listed since: 07-17-2025

    • 60,319 miles
    • 1 accident, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Toyota of Dallas (482 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 482 miles away from Tupelo, MS

    Experience the Thrill of Precision and Power with the 2022 Lexus IS 350 F SPORT in Cloudburst Gray Step into a world of refined performance and sophis...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21N5050780
    Stock: N5050780
    Certified Pre-Owned: No
    Listed since: 05-29-2025

    • 43,376 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Mercedes-Benz of Birmingham (127 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Irondale, AL / 127 miles away from Tupelo, MS

    This vehicle is located at our Irondale Campus** Black w/Blue w/F SPORT NuLuxe Seat Trim** Aluminum Sport Pedals** Black Headliner** Dark Gray Streaml...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29L5036218
    Stock: R036218
    Certified Pre-Owned: No
    Listed since: 07-09-2025

    • 38,236 miles
    • No accidents, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Scenic Chevrolet (323 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in West Union, SC / 323 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21N5049161
    Stock: C280641A
    Certified Pre-Owned: No
    Listed since: 06-24-2025

  • $42,987
    great price
    $6,491 below market
    • 28,609 miles
    • No accidents, 1 owner, personal use only
    • 19 City / 26 Hwy MPG
    • Athens Ford (298 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Athens, GA / 298 miles away from Tupelo, MS

    Clean CARFAX.2023 Lexus IS 350 F SPORT 3.5L V6 DOHC Dual VVT-i 24V AWD Ultra White2023 Lexus IS, Super clean, Clean Carfax, Local Trade In, Forward co...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E20P5031734
    Stock: KD93904A
    Certified Pre-Owned: No
    Listed since: 06-21-2025

    • 54,403 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Wells Auto Group (463 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Mckinney, TX / 463 miles away from Tupelo, MS

    2022 Lexus IS 350 F SPORT Black w/Black Metallic w/NuLuxe Seat Trim. CARFAX One-Owner. Clean CARFAX.Most of our vehicles also pre-qualify for up to ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24N5050398
    Stock: N5050398
    Certified Pre-Owned: No
    Listed since: 05-23-2025

    • 11,578 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • eCarOne (474 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Plano, TX / 474 miles away from Tupelo, MS

    IS 350 F SPORT: NAVI PKG W/MARK LEVINSON... INTUITIVE PARK ASST... TRIPLE BEAM HEADLIGHTS... HANDLING PKG... SUNROOF... MEMORY PKG... PREM PAINT... IL...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B20P5071705
    Stock: PP5071705
    Certified Pre-Owned: No
    Listed since: 05-27-2025

    • 50,672 miles
    • No accidents, 1 owner, personal use
    • 19 City / 26 Hwy MPG
    • Nalley Hyundai (266 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lithonia, GA / 266 miles away from Tupelo, MS

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E22N5025964
    Stock: NHYP220803
    Certified Pre-Owned: No
    Listed since: 07-08-2025

  • New Listing
    • 39,929 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NV to MS*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Las Vegas, NV / 1,500 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28L5035755
    Stock: 27068030
    Certified Pre-Owned: No

  • New Listing
    • 25,128 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • CarMax Norcross (259 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Norcross, GA / 259 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B22N5054322
    Stock: 27514161
    Certified Pre-Owned: No

  • New Listing
    • 46,356 miles
    • No accidents, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Carvana - Indianapolis (404 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Indianapolis, IN / 404 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHSZ1B24N5050590
    Stock: 2003876048
    Certified Pre-Owned: No
    Listed since: 07-15-2025

  • New Listing
    • 70,001 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 19 City / 26 Hwy MPG
    • Chandler Chevrolet (360 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Madison, IN / 360 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E2XN5024075
    Stock: T6888A
    Certified Pre-Owned: No
    Listed since: 07-22-2025

  • Price Drop
    • 54,912 miles
    • No accidents, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Carvana - Charlotte (451 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Charlotte, NC / 451 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B25N5051186
    Stock: 2003870029
    Certified Pre-Owned: No
    Listed since: 07-14-2025

Showing 106 - 126 out of 346 listings

Consumer Reviews for the Lexus IS 350

Read recent reviews for the Lexus IS 350
Overall Consumer Rating
4.6 out of 5 stars13 Reviews
Write a vehicle reviewSee all 13 reviews
  • 5 star
    (69%)
  • 4 star
    (23%)
  • 3 star
    (8%)
  • 2 star
    (0%)
  • 1 star
    (0%)
4 out of 5 stars

Great car, with a few exceptions

Tom B, 03/02/2017
2014 Lexus IS 350 4dr Sedan AWD (3.5L 6cyl 6A)
I lease a Lexus IS350 with the F-Sport option, and for the past 3 years it has been a lot of fun to drive. I turn mine in this May so I figured I have enough experience with it to write an honest review. First of all, I'm not a race car driver, so I don't much to compare against. But this car feels very sporty to me, has plenty of pickup, good handling, and a snappy suspension. The … infotainment system is fantastic. I especially love the 2nd display sitting behind the steering wheel. It's top-notch; plenty of bling and wow factor when you show a friend how the main dial moves over to reveal a 2nd screen. And it's functional, allowing you to do 2 things at once (music + navigation for example). The voice activation is decent enough. I really grew to like the center console "mouse" so if you test drive this car, don't be too put off by it. It grows on you. There is one big negative though, and you should know this before purchasing or leasing. The road noise is excessive. I realize this is a sporty car that sits low to the ground, but that shouldn't be an excuse for having to jack up the volume on your music at 55 MPH on a road that isn't all that old. And yes, this is with the standard tires AND with new replacements. The bottom carriage of the car simply does not have enough insulation to block out what is happening underneath. It wasn't a deal-breaker for me, but I can imagine some people would hate it. If you test drive, make sure to insist driving the car on a highway, preferrably one that hasn't been re-surfaced in the past couple years.
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Used 2022 Lexus IS 350 in Tupelo, MS Values

Estimated values
2022 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$33,024$34,896$36,849
Clean$32,472$34,272$36,150
Average$31,551$33,233$34,984
Rough$30,354$31,883$33,468

The average list price of a used 2022 Lexus IS 350 in Tupelo, Mississippi is $40,654. The average mileage on a used Lexus IS 350 2022 for sale in Tupelo, Mississippi is 40,957. Based on the average mileage of 40,957 for used 2022 Lexus IS 350 for sale in Tupelo, MS and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2022 in Tupelo, Mississippi to be $31,551.

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