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218 listings
  • Price Drop
    • 25,029 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sacramento, CA / 1,481 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC086529
    Stock: 26945902
    Certified Pre-Owned: No

  • New Listing
    • 27,995 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Los Angeles, CA / 1,439 miles away from Des Moines, IA

    Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heads-Up Display,Heated Seats,Heated Steering Wheel,Key...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXNC073524
    Stock: FP073524
    Certified Pre-Owned: No

  • Price Drop
    $49,990
    fair price
    $1,688 above market
    • 29,655 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Birmingham, AL / 671 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC081163
    Stock: 2003713293
    Certified Pre-Owned: No
    Listed since: 05-07-2025

    • 45,907 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Smart Lexus (156 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Davenport, IA / 156 miles away from Des Moines, IA

    Certified. Caviar 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V For more info. please call TJ Deere Manager 5**-4**-4***, 3.5L V6 DOHC VVT-i 24V,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC086198
    Stock: L1N086198
    Certified Pre-Owned: No
    Listed since: 01-23-2025

  • New Listing
    • 40,079 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NC to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Raleigh, NC / 891 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC077569
    Stock: 26262259
    Certified Pre-Owned: No

  • New Listing
    • 17,667 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Victorville, CA / 1,375 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC094339
    Stock: 27492986
    Certified Pre-Owned: No

    • 27,216 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Willis Lexus (8 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Des Moines, IA / 8 miles away from Des Moines, IA

    AWD, ONE OWNER, WELL MAINTAINED VEHICLE-Apple CarPlay/Android Auto.-Exterior Parking Camera Rear.--Heated / Ventilated Front Seats.-Heated Leather Ste...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC082334
    Stock: LX5547
    Certified Pre-Owned: Yes
    Listed since: 04-19-2025

  • Stock photo**
    • 68,345 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tom Roush Lincoln (412 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fishers, IN / 412 miles away from Des Moines, IA

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V**ONE OWNER**, **NO ACCIDENTS**, **LEATHER SEATS**, **PANORAMIC SUNROOF/MOONROOF**...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC083161
    Stock: L25096A
    Certified Pre-Owned: No
    Listed since: 05-31-2025

Showing 211 - 218 out of 218 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.5 out of 5 stars63 Reviews
Write a vehicle reviewSee all 63 reviews
  • 5 star
    (78%)
  • 4 star
    (11%)
  • 3 star
    (5%)
  • 2 star
    (2%)
  • 1 star
    (5%)
4.88 out of 5 stars

RX450h

ebaxley, 04/04/2011
2011 Lexus RX 450h 4dr SUV (3.5L 6cyl gas/electric hybrid CVT)
Overall, great. Fuel economy is better than Highlander Hybrid I owned before. Getting over 29mpg overall, over 30 if I use pure gas. About 26-27 on Interstate. Apparently 87 octane is OK, no pinging. Mpg no different with high-test. Features were quite onerous at first but"I'm catching on". Most disappointing feature is , by far, GPS. Map base is outdated, voice recognition poor and … some functions won't operate while moving. I realize you shouldn't be inputting while driving but sometimes you have a co-pilot. I have solved problem by mounting a Garmin on the dash. Marvelous ride!
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Used 2022 Lexus RX 450h in Des Moines, IA Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$35,116$36,530$38,003
Clean$34,648$36,024$37,456
Average$33,868$35,181$36,546
Rough$32,855$34,084$35,362

The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $49,606. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 35,237. Based on the average mileage of 35,237 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $33,868.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.