Skip to FiltersReport abuse
213 listings
- $45,998fair price$1,409 below market
- 48,468 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Flow Lexus of Winston Salem (487 mi away)
Close
Located in Winston Salem, NC / 487 miles away from Tupelo, MS
How about this great vehicle! It just arrived on our lot, and surely won't be here long! With fewer than 50,000 miles on the odometer, this 4 door spo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA3MC071162
Stock: 39308A
Certified Pre-Owned: Yes
Listed since: 08-18-2025 - New Listing$36,995fair price$210 above market
- 79,375 miles
- No accidents, 2 owners, rental vehicle
- 5 Seats, 31 City / 28 Hwy MPG
- Rick McGill's Airport Toyota (287 mi away)
Close
Located in Alcoa, TN / 287 miles away from Tupelo, MS
Auto Dual Zone Climate Control Sys w/Rear Vents Power NuLuxe-trimmed Front Seats Power Tilt-and-Telescopic Steering Column Reclining/Sliding 40/20/40 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7MC058364
Stock: T250724A
Certified Pre-Owned: No
Listed since: 08-27-2025 - Price Drop
- 49,499 miles
- Frame damage reported, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Drive A Dream (237 mi away)
Close
Located in Marietta, GA / 237 miles away from Tupelo, MS
AWD! LEATHER HEATED COOLED SEATS, SUNROOF, REAR VIEW CAMERA, SMART KEY, PUSH BUTTON START, ANDROID AUTO, APPLE CARPLAY, BLUETOOTH AUDIO STREAMING, SAT...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Issue reported
Salvage Vehicle: No
Frame Damage: Yes
Theft History: No
Lemon Status: Yes
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2MC065335
Stock: MC065335
Certified Pre-Owned: No
Listed since: 04-16-2025 - 82,625 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Stokes Toyota Hilton Head (469 mi away)
Close
Located in Bluffton, SC / 469 miles away from Tupelo, MS
***Stokes Toyota Hilton Head*** Local Trade** Loaded** 2021 Lexus RX 450h in Atomic Silver, Factory Equipped With:Multimedia:Apple CarPlay/Android Aut...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0MC069447
Stock: 35399A
Certified Pre-Owned: No
Listed since: 07-30-2025- $47,999great price$6,738 below market
- 21,168 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Stokes Toyota Hilton Head (469 mi away)
Close
Located in Bluffton, SC / 469 miles away from Tupelo, MS
***Stokes Toyota Hilton Head*** Loaded** Navigation** Levinson Sound** 2022 Lexus RX 450h in Eminent White Pearl, Factory Equipped With: 4-Way Power L...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA7NC089293
Stock: 35215A
Certified Pre-Owned: No
Listed since: 06-26-2025 - New Listing
- 60,435 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Jim Hudson Buick GMC (441 mi away)
Close
Located in Columbia, SC / 441 miles away from Tupelo, MS
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA8MC057000
Stock: B5321A
Certified Pre-Owned: No
Listed since: 08-21-2025 - Price Drop$41,500great price$5,618 below market
- 61,055 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Joe Machens Hyundai (381 mi away)
Close
Located in Columbia, MO / 381 miles away from Tupelo, MS
AVAILABLE AT JOE MACHENS HYUNDAI!CALL 573-474-7400 TODAY!2022 Lexus RX 450h 3.5L V6 DOHC VVT-i 24V, AWDNebula Gray Pearl w/ Black Leather Inte...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA2NC087970
Stock: NC087970
Certified Pre-Owned: No
Listed since: 07-30-2025 - Price Drop$47,990fair price$97 below market
- 20,261 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Westfield (421 mi away)
Close
Located in Westfield, IN / 421 miles away from Tupelo, MS
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 450h F Sport, 4D Sport Utili...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2SGMDAXNC083993
Stock: STK083993
Certified Pre-Owned: No
Listed since: 07-18-2025 - $46,492fair price
- 45,096 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- AutoNation USA Houston (497 mi away)
- Five Star Dealer
Close
Located in Houston, TX / 497 miles away from Tupelo, MS
12.3" Navigation System W/Mark Levinson AudioPremium Triple-Beam Led Headlamps (Ip)Panoramic-View Monitor W/Rr Cross-Traffic BrakingPanoramic Roof...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA2NC077079
Stock: NC077079
Certified Pre-Owned: No
Listed since: 08-11-2025 - New Listing$39,899good price$2,104 below market
- 59,096 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Reliable Superstore (324 mi away)
Close
Located in Springfield, MO / 324 miles away from Tupelo, MS
Cold Weather Package, Front Illuminated Aluminum Scuff Plates, Headlamp Auto-Leveling, Headlamp Washers, Heated Hard Maple Steering Wheel w/Paddle Shi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA0LC048517
Stock: LC048517
Certified Pre-Owned: No
Listed since: 08-28-2025 - $40,990fair price
- 33,850 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana - Dallas (477 mi away)
- Home delivery*
Close
Located in Dallas, TX / 477 miles away from Tupelo, MS
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1LC055801
Stock: 2003929900
Certified Pre-Owned: No
Listed since: 07-26-2025 - New Listing$50,975good price
- 21,238 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Park Place Lexus Grapevine (491 mi away)
Close
Located in Grapevine, TX / 491 miles away from Tupelo, MS
Certified. Odometer is 21080 miles below market average! Clean CARFAX. CARFAX One-Owner.3.5L V6 DOHC VVT-i 24V, AWD, Glazed Caramel Leather, 12.3" N...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA6NC090286
Stock: PLG252659A
Certified Pre-Owned: Yes
Listed since: 08-29-2025 - Price Drop$50,495fair price$1,502 below market
- 25,252 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- AutoNation Toyota Mall of Georgia (269 mi away)
Close
Located in Buford, GA / 269 miles away from Tupelo, MS
The following items have been reconditioned on this vehicle: all new tires! 12.3" Navigation System W/Mark Levinson AudioPremium Triple-Beam Led H...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA0NC089831
Stock: NC089831
Certified Pre-Owned: No
Listed since: 08-13-2025 - $33,998fair price$262 below market
- 90,990 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Flow Lexus of Winston Salem (487 mi away)
Close
Located in Winston Salem, NC / 487 miles away from Tupelo, MS
Looking for a used car at an affordable price? This vehicle won't be on the lot long! Distinctive design and opulent equipment are standard. Lexus inf...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2LC052826
Stock: 39053A
Certified Pre-Owned: No
Listed since: 08-02-2025 - $45,911fair price
- 35,495 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Pat Lobb's Toyota of McKinney (464 mi away)
Close
Located in Mckinney, TX / 464 miles away from Tupelo, MS
***F-SPORT PACKAGE***, ***LEVINSON AUDIO***, ***CARFAX One-Owner. Clean CARFAX. NEW ARRIVAL, WARRANTY--WARRANTY--WARRANTY INCLUDED!!!!, Priced for Qui...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2SGMDA3NC076268
Stock: P22553
Certified Pre-Owned: No
Listed since: 07-01-2025 - New Listing$48,990fair price
- 29,287 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana - Dallas (477 mi away)
- Home delivery*
Close
Located in Dallas, TX / 477 miles away from Tupelo, MS
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA5NC081130
Stock: 2003978237
Certified Pre-Owned: No
Listed since: 08-27-2025 - Price Drop$43,995fair price$953 above market
- 37,087 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Elwood (440 mi away)
Close
Located in Elwood, IN / 440 miles away from Tupelo, MS
Navigation, Back Up Camera, Sunroof, Bluetooth, Touch Screen, Heated Seats, Heated Steering Wheel, Power Lift Gate, Blind Spot, Low Miles, Lane Assist...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC092919
Stock: STK092919
Certified Pre-Owned: No
Listed since: 07-18-2025 - Price Drop
- 76,416 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Cadillac of Birmingham (124 mi away)
Close
Located in Birmingham, AL / 124 miles away from Tupelo, MS
Vehicle DetailsDiscover the unparalleled sophistication and performance of the 2022 Lexus RX 450h F SPORT Handling, an exquisite blend of luxu...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA0NC072592
Stock: 125152
Certified Pre-Owned: No
Listed since: 08-23-2025 - Price Drop
- 39,772 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Audi Creve Couer (318 mi away)
Close
Located in Creve Coeur, MO / 318 miles away from Tupelo, MS
RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC083606
Stock: PLAP220818
Certified Pre-Owned: No
Listed since: 06-30-2025 - Price Drop
- 85,813 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- AutoNation USA Kennesaw (235 mi away)
Close
Located in Kennesaw, GA / 235 miles away from Tupelo, MS
Power Tilt & Slide MoonroofBlind Spot Monitor & Rear Cross-Traffic AlertPremium PackageHeated & Ventilated Front SeatsSun/MoonroofAll-Weather Flo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5LC055414
Stock: LC055414
Certified Pre-Owned: No
Listed since: 06-30-2025 - Price Drop
- 44,351 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Noblesville (423 mi away)
Close
Located in Noblesville, IN / 423 miles away from Tupelo, MS
4x4, AWD, Back Up Camera, Bluetooth, Heated Seats, Sun/Moon Roof, Push Button Start, and much more ..., Touch Screen, RX 450h, 4D Sport Utility, 3.5L ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC084338
Stock: STK084338
Certified Pre-Owned: No
Listed since: 07-28-2025
Showing 1 - 21 out of 213 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2021 Lexus RX 450h in Tupelo, MS Values
Estimated values
2021 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $32,048 | $34,229 | $36,413 |
| Clean | $31,547 | $33,686 | $35,825 |
| Average | $30,713 | $32,780 | $34,846 |
| Rough | $29,628 | $31,602 | $33,573 |
The average list price of a used 2021 Lexus RX 450h in Tupelo, Mississippi is $42,849. The average mileage on a used Lexus RX 450h 2021 for sale in Tupelo, Mississippi is 49,839. Based on the average mileage of 49,839 for used 2021 Lexus RX 450h for sale in Tupelo, MS and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2021 in Tupelo, Mississippi to be $30,713.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.