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83 listings
- New Listing$42,980great price$5,961 below market
- 61,055 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Joe Machens Hyundai (117 mi away)
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Located in Columbia, MO / 117 miles away from Saint Louis, MO
AVAILABLE AT JOE MACHENS HYUNDAI!CALL 573-474-7400 TODAY!2022 Lexus RX 450h 3.5L V6 DOHC VVT-i 24V, AWDNebula Gray Pearl w/ Black Leather Inte...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA2NC087970
Stock: NC087970
Certified Pre-Owned: No
Listed since: 07-30-2025 - $50,540fair price$208 below market
- 38,501 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Mungenast Lexus of St Louis (16 mi away)
- Home delivery*
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Located in Manchester, MO / 16 miles away from Saint Louis, MO
L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC092467
Stock: P1421
Certified Pre-Owned: Yes
Listed since: 07-04-2025 - Price Drop
- 39,772 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Audi Creve Couer (14 mi away)
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Located in Creve Coeur, MO / 14 miles away from Saint Louis, MO
RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC083606
Stock: PLAP220818
Certified Pre-Owned: No
Listed since: 06-30-2025 - New Listing$44,590great price$2,365 below market
- 33,379 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Phoenix, AZ / 1,267 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA6MC068108
Stock: 2003831187
Certified Pre-Owned: No
Listed since: 08-05-2025 - $40,998fair price$226 above market
- 36,048 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from AZ to MO*
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Located in Tolleson, AZ / 1,281 miles away from Saint Louis, MO
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA6MC063801
Stock: 27003316
Certified Pre-Owned: No - Price Drop$38,425fair price$171 below market
- 44,252 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
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Located in Oxnard, CA / 1,633 miles away from Saint Louis, MO
CarFax No Accidents Reported,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steeri...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0MC070873
Stock: MC070873A
Certified Pre-Owned: No - New Listing$42,965fair price$760 below market
- 36,248 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
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Located in Cranberry, PA / 558 miles away from Saint Louis, MO
CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA4MC070147
Stock: T070147P
Certified Pre-Owned: No - New Listing$43,998fair price$327 above market
- 36,636 miles
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from NJ to MO*
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Located in Sicklersville, NJ / 816 miles away from Saint Louis, MO
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1MC058053
Stock: 27573860
Certified Pre-Owned: No - $40,998good price$1,482 below market
- 54,832 miles
- 4 accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from SC to MO*
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Located in Columbia, SC / 594 miles away from Saint Louis, MO
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA2MC060619
Stock: 26973216
Certified Pre-Owned: No - New Listing$28,511fair price$320 above market
- 105,018 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Schicker Ford of Union (45 mi away)
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Located in Union, MO / 45 miles away from Saint Louis, MO
EquipmentYou'll never again be lost in a crowded city or a country region with the navigation system on the Lexus RX 450h. This vehicle is a certifie...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCAXKC040140
Stock: P6688
Certified Pre-Owned: No
Listed since: 08-01-2025 - 59,147 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
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Located in Wesley Chapel, FL / 845 miles away from Saint Louis, MO
Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping Ass...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1MC061969
Stock: MC061969A
Certified Pre-Owned: No- 25,837 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
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Located in Houston, TX / 675 miles away from Saint Louis, MO
Low Mileage,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2MC069174
Stock: MC069174P
Certified Pre-Owned: No- New ListingNot Priced
- 90,450 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Genesis of Bloomington-Normal (146 mi away)
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Located in Normal, IL / 146 miles away from Saint Louis, MO
Moonroof, Navigation, Heated Seats, iPod/MP3 Input, Satellite Radio, Hybrid, Power Liftgate, All Wheel Drive, PANORAMIC VIEW MONITOR W/RR CROSS-TRA......
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA0MC069076
Stock: G299687A
Certified Pre-Owned: No
Listed since: 08-03-2025 - $46,590great price$5,909 below market
- 37,221 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Phoenix, AZ / 1,267 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA1NC089127
Stock: 2003775711
Certified Pre-Owned: No
Listed since: 05-30-2025 - $41,590good price$3,089 below market
- 27,492 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Sacramento, CA / 1,680 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA8LC055411
Stock: 2003848641
Certified Pre-Owned: No
Listed since: 07-02-2025 - $42,900great price$3,239 below market
- 50,687 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- McLaughlin Cadillac (197 mi away)
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Located in Moline, IL / 197 miles away from Saint Louis, MO
2022 Lexus RX 450h Black AWD eCVT 3.5L V6 DOHC VVT-i 24V3.5L V6 DOHC VVT-i 24V, AWD, Birch Artificial Leather, 4-Wheel Disc Brakes, ABS brakes, Alloy ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC078151
Stock: C2582A
Certified Pre-Owned: No
Listed since: 03-10-2025 - $44,590good price
- 52,394 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Dallas, TX / 546 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA8NC086742
Stock: 2003874190
Certified Pre-Owned: No
Listed since: 07-14-2025 - $45,998good price
- 29,876 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from TX to MO*
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Located in Corpus Christi, TX / 861 miles away from Saint Louis, MO
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC077999
Stock: 26403175
Certified Pre-Owned: No - $46,590fair price
- 29,821 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Dallas, TX / 546 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA9NC081163
Stock: 2003713293
Certified Pre-Owned: No
Listed since: 05-07-2025 - $43,998fair price$1,325 below market
- 40,485 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from PA to MO*
Close
Located in Mechanicsburg, PA / 711 miles away from Saint Louis, MO
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC092307
Stock: 27459841
Certified Pre-Owned: No - $42,590fair price
- 33,850 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Dallas, TX / 546 miles away from Saint Louis, MO
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1LC055801
Stock: 2003929900
Certified Pre-Owned: No
Listed since: 07-26-2025
Showing 1 - 21 out of 83 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2022 Lexus RX 450h in Saint Louis, MO Values
Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $34,445 | $36,065 | $37,752 |
| Clean | $33,986 | $35,565 | $37,209 |
| Average | $33,221 | $34,733 | $36,305 |
| Rough | $32,227 | $33,650 | $35,129 |
The average list price of a used 2022 Lexus RX 450h in Saint Louis, Missouri is $42,887. The average mileage on a used Lexus RX 450h 2022 for sale in Saint Louis, Missouri is 45,857. Based on the average mileage of 45,857 for used 2022 Lexus RX 450h for sale in Saint Louis, MO and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Saint Louis, Missouri to be $33,221.
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