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103 listings
  • $44,995
    great price
    $4,719 below market
    • 26,085 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Palm Beach (50 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in West Palm Beach, FL / 50 miles away from Port Saint Lucie, FL

    Luxury Package12.3" Navigation System W/Mark Levinson AudioPremium Triple-Beam Led Headlamps (Ip)Panoramic MoonroofPanoramic View Monitor W/Rr Cro...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4MC058548
    Stock: MC058548
    Certified Pre-Owned: Yes
    Listed since: 08-21-2025

  • Price Drop
    $36,989
    great price
    $3,498 below market
    • 61,135 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Sun Toyota (148 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Holiday, FL / 148 miles away from Port Saint Lucie, FL

    Sun Toyotas Real Nationwide Lifetime Powertrain WarrantyDrive with confidence knowing your investment is backed by our exclusive Sun Toyota Lifetime P...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA5MC064735
    Stock: I064735
    Certified Pre-Owned: No
    Listed since: 07-24-2025

    • 38,355 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of North Miami (102 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in North Miami, FL / 102 miles away from Port Saint Lucie, FL

    RX 450h F Sport Mark Levinson, AWD, Nebula Gray Pearl, Circuit Red w/F SPORT NuLuxe Seat Trim, 12.3" Navigation System w/Mark Levinson Audio, Adaptive...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA6NC086383
    Stock: 25361902
    Certified Pre-Owned: Yes
    Listed since: 07-16-2025

    • 82,625 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Stokes Toyota Hilton Head (343 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Bluffton, SC / 343 miles away from Port Saint Lucie, FL

    ***Stokes Toyota Hilton Head*** Local Trade** Loaded** 2021 Lexus RX 450h in Atomic Silver, Factory Equipped With:Multimedia:Apple CarPlay/Android Aut...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0MC069447
    Stock: 35399A
    Certified Pre-Owned: No
    Listed since: 07-30-2025

  • $47,999
    great price
    $6,679 below market
    • 21,168 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Stokes Toyota Hilton Head (343 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Bluffton, SC / 343 miles away from Port Saint Lucie, FL

    ***Stokes Toyota Hilton Head*** Loaded** Navigation** Levinson Sound** 2022 Lexus RX 450h in Eminent White Pearl, Factory Equipped With: 4-Way Power L...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA7NC089293
    Stock: 35215A
    Certified Pre-Owned: No
    Listed since: 06-26-2025

  • New Listing
    • 60,435 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Jim Hudson Buick GMC (470 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbia, SC / 470 miles away from Port Saint Lucie, FL

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8MC057000
    Stock: B5321A
    Certified Pre-Owned: No
    Listed since: 08-21-2025

  • New Listing
    $47,490
    good price
    $1,979 below market
    • 20,055 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Rick Case Kia (83 mi away)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sunrise, FL / 83 miles away from Port Saint Lucie, FL

    Recent Arrival! CARFAX One-Owner. Clean CARFAX. 10 year or 100,000 mile Powertrain Warranty, 150 Point Inspection, Unlimited Car Wash, Rick Case Rewar...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0NC093300
    Stock: TNC093300
    Certified Pre-Owned: No
    Listed since: 08-24-2025

  • Price Drop
    $41,600
    good price
    $2,230 below market
    • 45,685 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Holman INEOS Grenadier (87 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Lauderdale, FL / 87 miles away from Port Saint Lucie, FL

    Holman INEOS Grenadier is pumped up to offer this gorgeous-looking 2022 Lexus RX Eminent White Pearl 450h with the following features:Apple CarPlay/An...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1NC092639
    Stock: NC092639
    Certified Pre-Owned: No
    Listed since: 07-25-2025

  • New Listing
    Stock photo**
    $44,852
    good price
    $3,073 below market
    • 51,189 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Mercedes-Benz of Tampa (129 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 129 miles away from Port Saint Lucie, FL

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA0NC078523
    Stock: CMT252757E
    Certified Pre-Owned: No
    Listed since: 08-23-2025

  • Price Drop
    $36,590
    fair price
    $495 below market
    • 67,602 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Tampa (126 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Tampa, FL / 126 miles away from Port Saint Lucie, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2LC043494
    Stock: 2003926739
    Certified Pre-Owned: No
    Listed since: 07-26-2025

  • New Listing
    Stock photo**
    $47,498
    fair price
    $900 below market
    • 30,839 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Pembroke Pines (93 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Pembroke Pines, FL / 93 miles away from Port Saint Lucie, FL

    2022 Lexus RX 450h Blue Recent Arrival! !!!*** HURRY ***!!!, *!*!*! DON'T MISS OUT !*!*!*, ** BEST COLOR COMBINATION **, 12.3 Navigation System, 18 Al...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC088475
    Stock: 25557401
    Certified Pre-Owned: No
    Listed since: 08-23-2025

  • Stock photo**
    $46,728
    fair price
    $1,154 above market
    • 26,887 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Fort Myers (100 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fort Myers, FL / 100 miles away from Port Saint Lucie, FL

    Heated Seats, Moonroof, All Wheel Drive, Satellite Radio, Hybrid, Back-Up Camera, Power Liftgate, HEATED LEATHER STEERING WHEEL, MOONROOF & ALUMINUM R...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC083539
    Stock: NC083539
    Certified Pre-Owned: Yes
    Listed since: 08-08-2025

  • New Listing
    $40,998
    good price
    $4,512 below market
    • 49,914 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from AZ to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Gilbert, AZ / 1,901 miles away from Port Saint Lucie, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1MC064694
    Stock: 27621349
    Certified Pre-Owned: No

  • New Listing
    $46,590
    fair price
    $1,050 above market
    • 14,487 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Richmond, VA / 732 miles away from Port Saint Lucie, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4MC068981
    Stock: 2003987857
    Certified Pre-Owned: No
    Listed since: 08-26-2025

  • $29,998
    good price
    $2,620 below market
    • 66,320 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Ft. Lauderdale (88 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Davie, FL / 88 miles away from Port Saint Lucie, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA8KC040704
    Stock: 27731436
    Certified Pre-Owned: No

  • Price Drop
    $40,250
    fair price
    $555 above market
    • 51,143 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Mercedes-Benz of Palm Beach (51 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in West Palm Beach, FL / 51 miles away from Port Saint Lucie, FL

    CARFAX One-Owner. Clean CARFAX. Alloy wheels, AM/FM radio: SiriusXM, Apple CarPlay/Android Auto, Driver Seat and Steering Wheel Memory, Exterior Parki...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5MC058718
    Stock: MB61341A
    Certified Pre-Owned: No
    Listed since: 08-06-2025

  • New Listing
    • 48,315 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Tampa (126 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Tampa, FL / 126 miles away from Port Saint Lucie, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCAXKC037500
    Stock: 2003991751
    Certified Pre-Owned: No
    Listed since: 08-15-2025

    • 36,249 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cranberry, PA / 923 miles away from Port Saint Lucie, FL

    CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4MC070147
    Stock: T070147P
    Certified Pre-Owned: No

  • Price Drop
    $44,590
    great price
    $6,873 below market
    • 37,221 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Phoenix, AZ / 1,919 miles away from Port Saint Lucie, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1NC089127
    Stock: 2003775711
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • $46,222
    great price
    $4,287 below market
    • 32,855 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Parks Chrysler Dodge Jeep Ram Space Coast (85 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Titusville, FL / 85 miles away from Port Saint Lucie, FL

    CARFAX One-Owner. New Price! 2022 Lexus RX 450h F Sport Located at Parks CDJR Space Coast in Titusville., All vehicles have cosmetic blemishes. Pricin...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA4NC078721
    Stock: SN722745C
    Certified Pre-Owned: No
    Listed since: 06-21-2025

  • $29,470
    great price
    $2,667 below market
    • 60,625 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tamiami Hyundai (109 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Naples, FL / 109 miles away from Port Saint Lucie, FL

    CARFAX One-Owner.2018 Lexus RX Caviar 4D Sport Utility 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V NAVIGATION, BACK UP CAMERA, THIRD ROW SEATING, PUSH BUTTON...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA7JC025657
    Stock: JC025657
    Certified Pre-Owned: No
    Listed since: 07-10-2025

Showing 1 - 21 out of 103 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (18%)
  • 3 star
    (9%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2021 Lexus RX 450h in Port Saint Lucie, FL Values

Estimated values
2021 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$31,947$34,151$36,356
Clean$31,448$33,609$35,770
Average$30,617$32,705$34,792
Rough$29,535$31,530$33,521

The average list price of a used 2021 Lexus RX 450h in Port Saint Lucie, Florida is $41,806. The average mileage on a used Lexus RX 450h 2021 for sale in Port Saint Lucie, Florida is 44,247. Based on the average mileage of 44,247 for used 2021 Lexus RX 450h for sale in Port Saint Lucie, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2021 in Port Saint Lucie, Florida to be $30,617.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.