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158 listings
- Price Drop$38,450good price$1,095 below market
- 61,135 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Sun Toyota (224 mi away)
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Located in Holiday, FL / 224 miles away from Panama City, FL
Sun Toyotas Real Nationwide Lifetime Powertrain WarrantyDrive with confidence knowing your investment is backed by our exclusive Sun Toyota Lifetime P...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2SGMDA5MC064735
Stock: I064735
Certified Pre-Owned: No
Listed since: 07-24-2025 - $44,803fair price$1,228 below market
- 37,297 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Knoxville (405 mi away)
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Located in Knoxville, TN / 405 miles away from Panama City, FL
Clean CARFAX. **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.The Optional Features Included on this are: Cold Weather Package (CT) (Headlamp Auto-Le...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA9MC065199
Stock: 2421A
Certified Pre-Owned: No
Listed since: 07-24-2025 - New Listing$37,999fair price$317 above market
- 82,625 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Stokes Toyota Hilton Head (316 mi away)
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Located in Bluffton, SC / 316 miles away from Panama City, FL
***Stokes Toyota Hilton Head*** Local Trade** Loaded** 2021 Lexus RX 450h in Atomic Silver, Factory Equipped With:Multimedia:Apple CarPlay/Android Aut...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0MC069447
Stock: 35399A
Certified Pre-Owned: No
Listed since: 07-30-2025 - 49,499 miles
- Frame damage reported, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Drive A Dream (270 mi away)
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Located in Marietta, GA / 270 miles away from Panama City, FL
AWD! LEATHER HEATED COOLED SEATS, SUNROOF, REAR VIEW CAMERA, SMART KEY, PUSH BUTTON START, ANDROID AUTO, APPLE CARPLAY, BLUETOOTH AUDIO STREAMING, SAT...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Issue reported
Salvage Vehicle: No
Frame Damage: Yes
Theft History: No
Lemon Status: Yes
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2MC065335
Stock: MC065335
Certified Pre-Owned: No
Listed since: 04-16-2025- Price Drop$49,640great price$5,491 below market
- 21,168 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Stokes Toyota Hilton Head (316 mi away)
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Located in Bluffton, SC / 316 miles away from Panama City, FL
***Stokes Toyota Hilton Head*** Loaded** Navigation** Levinson Sound** 2022 Lexus RX 450h in Eminent White Pearl, Factory Equipped With: 4-Way Power L...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA7NC089293
Stock: 35215A
Certified Pre-Owned: No
Listed since: 06-26-2025 - $44,490great price$6,882 below market
- 19,290 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- North Miami Mitsubishi (444 mi away)
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Located in Miami Gardens, FL / 444 miles away from Panama City, FL
2022 Lexus RX 450h F Sport Caviar 4D Sport Utility 3.5L V6 DOHC VVT-i 24V3.5L V6 DOHC VVT-i 24V, AWD, Black w/F SPORT NuLuxe Seat Trim, Forward coll...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA6NC085024
Stock: 085024C01
Certified Pre-Owned: No
Listed since: 03-18-2025 - 59,147 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (239 mi away)
- Home delivery*
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Located in Wesley Chapel, FL / 239 miles away from Panama City, FL
Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping Ass...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1MC061969
Stock: MC061969A
Certified Pre-Owned: No- $45,888great price$5,589 below market
- 38,355 miles
- No accidents, 3 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of North Miami (448 mi away)
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Located in North Miami, FL / 448 miles away from Panama City, FL
RX 450h F Sport Mark Levinson, AWD, Nebula Gray Pearl, Circuit Red w/F SPORT NuLuxe Seat Trim, 12.3" Navigation System w/Mark Levinson Audio, Adaptive...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA6NC086383
Stock: 25361902
Certified Pre-Owned: Yes
Listed since: 07-16-2025 - New ListingNot Priced
- 30,663 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Germain Lexus of Naples (358 mi away)
- Five Star Dealer
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Located in Naples, FL / 358 miles away from Panama City, FL
3.5L V6 DOHC VVT-i 24V, AWD. Recent Arrival! 2021 Lexus RX 450h *Payment is plus tax and fees, contact dealer for details. For your peace of mind we h...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2MC071989
Stock: L251490B
Certified Pre-Owned: No
Listed since: 08-04-2025 - Price Drop$38,900good price$2,901 below market
- 56,403 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Nalley Lexus Smyrna (265 mi away)
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Located in Smyrna, GA / 265 miles away from Panama City, FL
RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1LC043793
Stock: NLS256469A
Certified Pre-Owned: Yes
Listed since: 07-07-2025 - $52,490fair price$2,173 below market
- 25,249 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Wesley Chapel (241 mi away)
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Located in Wesley Chapel, FL / 241 miles away from Panama City, FL
Panorama MoonroofNavigation with Mark Levinson Upgraded AudioCARFAX One-Owner. Clean CARFAX. Certified. Ultra White 2022 Lexus RX 450h F Sport AWD eCV...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA3NC089208
Stock: T089208
Certified Pre-Owned: Yes
Listed since: 07-23-2025 - $37,749great price$1,403 below market
- 74,145 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Mike Johnsons Hickory Toyota (457 mi away)
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Located in Hickory, NC / 457 miles away from Panama City, FL
Caviar 2020 Lexus RX 450h F Sport AWD eCVT 3.5L V6 DOHC VVT-i 24VRecent Arrival! 31/28 City/Highway MPGRX 450h F Sport, 4D Sport Utility, 3.5L V6 DOHC...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDAXLC056056
Stock: 65558A
Certified Pre-Owned: No
Listed since: 07-21-2025 - $46,995good price$2,954 below market
- 12,585 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Palm Beach (414 mi away)
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Located in West Palm Beach, FL / 414 miles away from Panama City, FL
12.3" Navigation SystemPanoramic-View Monitor W/Rr Cross-Traffic BrakingMoonroof & Aluminum Roof RailsWheels: 20" Split 5-Spoke W/Dark Silver Paint...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC092873
Stock: NC092873
Certified Pre-Owned: Yes
Listed since: 07-29-2025 - New Listing$40,487fair price$119 above market
- 66,420 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Music City Autoplex (427 mi away)
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Located in Nashville, TN / 427 miles away from Panama City, FL
CLEAN CARFAX NO ACCIDENTS REPORTED, ONE OWNER, REAR VIEW BACK-UP CAMERA, BLUETOOTH HANDS-FREE CALLING, AWD/ALL WHEEL DRIVE, NAVIGATION/GPS, HEATED AND...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC087384
Stock: 1835
Certified Pre-Owned: No
Listed since: 08-05-2025 - Price Drop$43,700fair price$756 below market
- 45,685 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Holman INEOS Grenadier (438 mi away)
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Located in Fort Lauderdale, FL / 438 miles away from Panama City, FL
Holman INEOS Grenadier is proud to offer this superb-looking 2022 Lexus RX Eminent White Pearl 450h with the following features:Apple CarPlay/Android ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1NC092639
Stock: NC092639
Certified Pre-Owned: No
Listed since: 07-25-2025 - New Listing$38,590fair price$1,188 above market
- 67,602 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana - Tampa (248 mi away)
- Home delivery*
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Located in Tampa, FL / 248 miles away from Panama City, FL
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2LC043494
Stock: 2003926739
Certified Pre-Owned: No
Listed since: 07-26-2025 - 16,924 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax Jacksonville West (235 mi away)
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Located in Jacksonville, FL / 235 miles away from Panama City, FL
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC084481
Stock: 27496594
Certified Pre-Owned: No- 85,813 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- AutoNation USA Kennesaw (272 mi away)
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Located in Kennesaw, GA / 272 miles away from Panama City, FL
Power Tilt & Slide MoonroofBlind Spot Monitor & Rear Cross-Traffic AlertPremium PackageHeated & Ventilated Front SeatsSun/MoonroofAll-Weather Flo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5LC055414
Stock: LC055414
Certified Pre-Owned: No
Listed since: 06-30-2025- New Listing$44,590great price$2,546 below market
- 33,379 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Phoenix, AZ / 1,561 miles away from Panama City, FL
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA6MC068108
Stock: 2003831187
Certified Pre-Owned: No
Listed since: 08-05-2025 - New Listing$42,971good price$3,698 below market
- 44,160 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Roadshow MINI (417 mi away)
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Located in Cordova, TN / 417 miles away from Panama City, FL
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA3MC067404
Stock: 32481H
Certified Pre-Owned: No
Listed since: 08-03-2025 - Price Drop$43,372good price$2,966 below market
- 33,729 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of New Orleans (272 mi away)
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Located in Metairie, LA / 272 miles away from Panama City, FL
CARFAX One-Owner. Clean CARFAX. Certified. Moonbeam Beige Metallic 2021 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V 3.5L V6 DOHC VVT-i 24V, AWD, Par...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA3MC069071
Stock: LE069071
Certified Pre-Owned: Yes
Listed since: 07-14-2025
Showing 1 - 21 out of 158 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2021 Lexus RX 450h in Panama City, FL Values
Estimated values
2021 Lexus RX 450h F SPORT 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $35,750 | $38,061 | $40,375 |
| Clean | $35,192 | $37,457 | $39,724 |
| Average | $34,261 | $36,450 | $38,638 |
| Rough | $33,051 | $35,140 | $37,227 |
The average list price of a used 2021 Lexus RX 450h in Panama City, Florida is $42,436. The average mileage on a used Lexus RX 450h 2021 for sale in Panama City, Florida is 45,775. Based on the average mileage of 45,775 for used 2021 Lexus RX 450h for sale in Panama City, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2021 in Panama City, Florida to be $34,261.
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