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156 listings
  • $42,726
    great price
    $4,186 below market
    • 34,708 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Jeff Wyler Florence Buick GMC (95 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Florence, KY / 95 miles away from Indianapolis, IN

    Jeff Wyler Florence Buick GMC is honored to offer this wonderful-looking 2021 Lexus RX 450h F Sport in White. 4-Wheel Disc Brakes, 9 Speakers, ABS bra...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDAXMC062690
    Stock: 26T9793
    Certified Pre-Owned: No
    Listed since: 05-03-2025

    • 121 miles
    • No accidents, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Woodfield Lexus (183 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Schaumburg, IL / 183 miles away from Indianapolis, IN

    **ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, **Lexus Safety System Plus**, ** Lane Departure Warning, *...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7MC070305
    Stock: Q3573
    Certified Pre-Owned: Yes
    Listed since: 03-22-2025

    • 8,267 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Woodfield Lexus (183 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Schaumburg, IL / 183 miles away from Indianapolis, IN

    **ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, **Lexus Safety System Plus**, ** Lane Departure Warning, *...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5MC064941
    Stock: Q3645
    Certified Pre-Owned: Yes
    Listed since: 05-20-2025

  • Price Drop
    $37,775
    great price
    $7,569 below market
    • 33,256 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Jeff Wyler Chrysler Jeep Dodge Ram Ft Thomas (101 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Thomas, KY / 101 miles away from Indianapolis, IN

    Jeff Wyler Chrysler Jeep Dodge Ram is very proud to offer this outstanding-looking 2020 Lexus RX 450h in Atomic Silver. Well equipped with: 3.5L V6 DO...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA0LC055029
    Stock: 23T9391
    Certified Pre-Owned: No
    Listed since: 02-24-2025

  • Price Drop
    $49,990
    great price
    $5,337 below market
    • 25,473 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Merrillville (130 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Merrillville, IN / 130 miles away from Indianapolis, IN

    UNLIMITED MILE COMPREHENSIVE WARRANTY THRU 10/11/2028!, PANORAMIC GLASS MOONROOF!, COLOR HEADS-UP DISPLAY!, MARK LEVINSON SOUND!, PANORAMIC VIEW MONIT...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA5NC092869
    Stock: PM2719
    Certified Pre-Owned: Yes
    Listed since: 04-02-2025

  • Price Drop
    $46,990
    good price
    $3,589 below market
    • 53,289 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Merrillville (130 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Merrillville, IN / 130 miles away from Indianapolis, IN

    2 YEAR/UNLIMITED MILE COMPREHENSIVE WARRANTY!, PANORAMIC GLASS MOONROOF!, COLOR HEADS-UP DISPLAY!, MARK LEVINSON SOUND!, PANORAMIC VIEW MONITOR!, LUXU...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA6NC076129
    Stock: PM26761
    Certified Pre-Owned: Yes
    Listed since: 04-23-2025

  • $48,100
    good price
    $2,852 below market
    • 30,819 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Twins Auto of Dublin (154 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dublin, OH / 154 miles away from Indianapolis, IN

    YOU ALWAYS WIN AT TWINS OF DUBLIN.2022 Lexus RX 450h F Sport **PANORAMIC ROOF**, **NAVIGATION**, **USB PORTS**, **ALL WHEEL DRIVE**, 3.5L V6 DOHC VVT...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA5NC084124
    Stock: D4112
    Certified Pre-Owned: No
    Listed since: 03-05-2025

  • Price Drop
    $35,983
    fair price
    $864 below market
    • 53,820 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • AutoNation Toyota Libertyville (192 mi away)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Libertyville, IL / 192 miles away from Indianapolis, IN

    12.3" Navigation SystemPanoramic View Monitor W/Blind Spot MonitorPower Tilt & Slide MoonroofWheels: 20" Split-5-Spoke Dark Silver AlloyPremium Pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2LC052311
    Stock: LC052311
    Certified Pre-Owned: No
    Listed since: 04-26-2025

  • Price Drop
    • 31,714 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Zeigler Subaru of Lafayette (55 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Lafayette, IN / 55 miles away from Indianapolis, IN

    Priced below KBB Fair Purchase Price! 2022 Lexus Eminent White Pearl AWD RX 450h eCVT Odometer is 1760 miles below market average! Heated & Ventilated...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC072479
    Stock: 3930LP
    Certified Pre-Owned: No
    Listed since: 04-01-2025

  • Price Drop
    • 36,029 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • McGrath Lexus of Chicago (163 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Chicago, IL / 163 miles away from Indianapolis, IN

    Recent Arrival! Ultra White 2022 Lexus RX 450h F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7NC087347
    Stock: U4706
    Certified Pre-Owned: Yes
    Listed since: 04-30-2025

  • New Listing
    • 46,886 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Louisville (119 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Louisville, KY / 119 miles away from Indianapolis, IN

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2NC078801
    Stock: 26483002
    Certified Pre-Owned: No

  • New Listing
    $39,998
    good price
    $3,727 below market
    • 63,192 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IN*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Oceanside, CA / 1,787 miles away from Indianapolis, IN

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9MC069612
    Stock: 27338566
    Certified Pre-Owned: No

  • New Listing
    $29,657
    good price
    $2,948 below market
    • 94,529 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Jeff Wyler Toyota of Clarksville (111 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Clarksville, IN / 111 miles away from Indianapolis, IN

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA7KC033310
    Stock: 31T14344B
    Certified Pre-Owned: No
    Listed since: 05-24-2025

  • Stock photo**
    $35,211
    good price
    $3,272 below market
    • 54,677 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Orland (151 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Orland Park, IL / 151 miles away from Indianapolis, IN

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA7KC040824
    Stock: LX06851
    Certified Pre-Owned: Yes
    Listed since: 05-17-2025

  • Price Drop
    $44,640
    good price
    $4,373 below market
    • 37,500 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Lexington (154 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lexington, KY / 154 miles away from Indianapolis, IN

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA7MC070094
    Stock: X37347A
    Certified Pre-Owned: Yes
    Listed since: 05-17-2025

  • Price Drop
    $35,590
    good price
    $1,944 below market
    • 56,226 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Indianapolis (12 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Indianapolis, IN / 12 miles away from Indianapolis, IN

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA6KC032584
    Stock: 2003686979
    Certified Pre-Owned: No
    Listed since: 05-03-2025

  • $39,821
    good price
    $1,862 below market
    • 49,123 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Fort Wayne (91 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Wayne, IN / 91 miles away from Indianapolis, IN

    2021 Lexus RX 450h Black AWDAt Bob Rohrman Dealerships Our selection is Outstanding. We believe that we truly have a certified preowned vehicle for ev...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA0MC069160
    Stock: FL1512P
    Certified Pre-Owned: No
    Listed since: 04-22-2025

  • $33,890
    good price
    $2,599 below market
    • 53,159 miles
    • 2 accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • McGrath Lexus of Chicago (163 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Chicago, IL / 163 miles away from Indianapolis, IN

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA2KC032341
    Stock: S645A
    Certified Pre-Owned: Yes
    Listed since: 02-04-2025

    • 25,837 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Houston, TX / 876 miles away from Indianapolis, IN

    Low Mileage,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2MC069174
    Stock: MC069174P
    Certified Pre-Owned: No

  • New Listing
    $34,990
    fair price
    $617 above market
    • 63,227 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Indianapolis (12 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Indianapolis, IN / 12 miles away from Indianapolis, IN

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA1KC041841
    Stock: 2003754293
    Certified Pre-Owned: No
    Listed since: 05-23-2025

  • Price Drop
    $41,590
    good price
    $1,484 below market
    • 44,167 miles
    • 1 accident, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cleveland, OH / 251 miles away from Indianapolis, IN

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXMC061856
    Stock: 2003667919
    Certified Pre-Owned: No
    Listed since: 04-29-2025

Showing 1 - 21 out of 156 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (18%)
  • 3 star
    (9%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2021 Lexus RX 450h in Indianapolis, IN Values

Estimated values
2021 Lexus RX 450h F SPORT 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$36,897$38,215$39,537
Clean$36,320$37,609$38,899
Average$35,360$36,597$37,836
Rough$34,111$35,283$36,454

The average list price of a used 2021 Lexus RX 450h in Indianapolis, Indiana is $42,558. The average mileage on a used Lexus RX 450h 2021 for sale in Indianapolis, Indiana is 42,668. Based on the average mileage of 42,668 for used 2021 Lexus RX 450h for sale in Indianapolis, IN and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2021 in Indianapolis, Indiana to be $35,360.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.