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398 listings
  • Price Drop
    $35,983
    fair price
    $856 below market
    • 53,820 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • AutoNation Toyota Libertyville (429 mi away)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Libertyville, IL / 429 miles away from Charleston, WV

    12.3" Navigation SystemPanoramic View Monitor W/Blind Spot MonitorPower Tilt & Slide MoonroofWheels: 20" Split-5-Spoke Dark Silver AlloyPremium Pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2LC052311
    Stock: LC052311
    Certified Pre-Owned: No
    Listed since: 04-26-2025

  • Price Drop
    $45,956
    fair price
    $1,380 above market
    • 27,315 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Boardwalk Honda (387 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Egg Harbor Township, NJ / 387 miles away from Charleston, WV

    Excellent Condition, LOW MILES - 27,315! WAS $47,300, FUEL EFFICIENT 28 MPG Hwy/31 MPG City! Heated Seats, Sunroof, NAV, Satellite Radio, Hybrid, Back...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC086513
    Stock: NC086513
    Certified Pre-Owned: No
    Listed since: 05-15-2025

  • Price Drop
    $50,590
    fair price
    $1,367 above market
    • 29,655 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Birmingham (442 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Birmingham, AL / 442 miles away from Charleston, WV

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC081163
    Stock: 2003713293
    Certified Pre-Owned: No
    Listed since: 05-07-2025

  • $42,813
    fair price
    $675 above market
    • 40,839 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Don Beyer Volvo Cars of Falls Church (243 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Falls Church, VA / 243 miles away from Charleston, WV

    VOLVO OF FALLS CHURCH!!!, Bluetooth Hands Free w/ Audio Streaming, RX 450h, 4D Sport Utility, 3.5L V6 DOHC VVT-i 24V, eCVT, AWD, Silver.CARFAX One-Own...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC080521
    Stock: E29547V
    Certified Pre-Owned: No
    Listed since: 05-09-2025

  • $45,998
    fair price
    $1,108 above market
    • 40,362 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Mechanicsburg (279 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Mechanicsburg, PA / 279 miles away from Charleston, WV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC092307
    Stock: 27459841
    Certified Pre-Owned: No

    • 69,007 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Furrst Class Cars (224 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Charlotte, NC / 224 miles away from Charleston, WV

    2020 LEXUS RX 450H -Clean CARFAX -Carolina Owned -69k Miles -3.5L V6 Hybrid -AWD -Apple CarPlay/Android Auto -12.3 Touchscreen w/ Remote Touchp...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5LC051508
    Stock: 8725
    Certified Pre-Owned: No
    Listed since: 04-21-2025

  • $41,990
    fair price
    $1,537 above market
    • 50,773 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (466 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wappingers Falls, NY / 466 miles away from Charleston, WV

    CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC079730
    Stock: WTP8317
    Certified Pre-Owned: No

  • Price Drop
    $47,435
    fair price
    $1,121 above market
    • 20,295 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Roberts Toyota (352 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbia, TN / 352 miles away from Charleston, WV

    LIFETIME WARRANTY - This vehicle comes with a complimentary, nationwide LIFETIME WARRANTY! Good at any licensed repair facility in the USA and Canada,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC080598
    Stock: P94464
    Certified Pre-Owned: No
    Listed since: 04-04-2025

    • 146 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Wilmington (339 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Wilmington, DE / 339 miles away from Charleston, WV

    **1 OWNER****CLEAN CARFAX****L-CERTIFIED****HEATED AND VENTILATED SEATS****PREMIUM PACKAGE****POWER MOONROOF**L/Certified Details: * Limited...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC089897
    Stock: RP089897
    Certified Pre-Owned: Yes
    Listed since: 05-13-2025

    • 21,182 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driver's Way (450 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pelham, AL / 450 miles away from Charleston, WV

    AWD, Glazed Caramel w/NuLuxe Seat Trim, Apple CarPlay/Android Auto, Auto High-beam Headlights, Automatic temperature control, Driver Seat & Steering W...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC085728
    Stock: D64659
    Certified Pre-Owned: No
    Listed since: 05-09-2025

    • 36,964 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Dulles (231 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sterling, VA / 231 miles away from Charleston, WV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1LC050727
    Stock: 27239128
    Certified Pre-Owned: No

    • 31,714 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Zeigler Subaru of Lafayette (312 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Lafayette, IN / 312 miles away from Charleston, WV

    Priced below KBB Fair Purchase Price! 2022 Lexus Eminent White Pearl AWD RX 450h eCVT Odometer is 1760 miles below market average! Heated & Ventilated...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC072479
    Stock: 3930LP
    Certified Pre-Owned: No
    Listed since: 04-01-2025

    • 40,068 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Hickory (184 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Hickory, NC / 184 miles away from Charleston, WV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC077569
    Stock: 26262259
    Certified Pre-Owned: No

  • Price Drop
    • 104,763 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • BMW of Catonsville (269 mi away)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Baltimore, MD / 269 miles away from Charleston, WV

    3.5L V6 DOHC VVT-i 24V, AWD, Driver Seat & Steering Wheel Memory, Premium Package, Wood Ornamentation.Recent Arrival! CARFAX One-Owner. 31/28 City/Hig...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0NC077534
    Stock: 451020A
    Certified Pre-Owned: No
    Listed since: 05-19-2025

    • 49,587 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana - Richmond (224 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Richmond, VA / 224 miles away from Charleston, WV

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2LC052888
    Stock: 2003724641
    Certified Pre-Owned: No
    Listed since: 05-08-2025

  • New Listing
    • 32,825 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Brooklyn (435 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brooklyn, NY / 435 miles away from Charleston, WV

    Looking for a quality used car? Here's why Lexus of Brooklyn is your top choice: Quality Assurance: Rigorous inspections ensure top-notch quality and ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC081733
    Stock: BX23305
    Certified Pre-Owned: No
    Listed since: 05-20-2025

  • New Listing
    • 46,886 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax Louisville (214 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Louisville, KY / 214 miles away from Charleston, WV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2NC078801
    Stock: 26483002
    Certified Pre-Owned: No

    • 36,029 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • McGrath Lexus of Chicago (402 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Chicago, IL / 402 miles away from Charleston, WV

    Recent Arrival! Ultra White 2022 Lexus RX 450h F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7NC087347
    Stock: U4706
    Certified Pre-Owned: Yes
    Listed since: 04-30-2025

    • 53,273 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Johnson Lexus of Durham (224 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Durham, NC / 224 miles away from Charleston, WV

    L-CERTIFIED SALES EVENT! PRICED WAY BELOW KBB CERTIFIED RETAIL VALUE OF $52,836 FOR A QUICK AND HASSLE-FREE SALE! 5.75% FINANCING FOR UP TO 72 MONTHS!...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA6NC078526
    Stock: DPL10676A
    Certified Pre-Owned: Yes
    Listed since: 05-09-2025

  • New Listing
    • 27,949 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Johnson Lexus of Raleigh (240 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Raleigh, NC / 240 miles away from Charleston, WV

    LEXUS CERTIFIED WITH UNLIMITED MILE WARRANTY!!BENEFITS OF LEXUS L/CERTIFIED VEHICLES:161-POINT INSPECTION - Lexus technicians put each pre-owned ve...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8LC054158
    Stock: R35582A
    Certified Pre-Owned: No
    Listed since: 05-23-2025

  • $39,755
    great price
    $5,975 below market
    • 25,856 miles
    • No accidents, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • South Shore Nissan (466 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Amityville, NY / 466 miles away from Charleston, WV

    3.5L V6 DOHC VVT-i 24V, AWD, Circuit Red w/F SPORT NuLuxe Seat Trim. Odometer is 20343 miles below market average! 2021 Lexus RX 450h F Sport AWD eCVT...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7MC058753
    Stock: U13572
    Certified Pre-Owned: No
    Listed since: 01-13-2025

Showing 43 - 63 out of 398 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (18%)
  • 3 star
    (9%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2020 Lexus RX 450h in Charleston, WV Values

Estimated values
2020 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$30,640$34,143$37,510
Clean$30,082$33,518$36,820
Average$29,153$32,477$35,669
Rough$27,945$31,123$34,173

The average list price of a used 2020 Lexus RX 450h in Charleston, West Virginia is $44,860. The average mileage on a used Lexus RX 450h 2020 for sale in Charleston, West Virginia is 39,967. Based on the average mileage of 39,967 for used 2020 Lexus RX 450h for sale in Charleston, WV and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2020 in Charleston, West Virginia to be $29,153.

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