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  • Price Drop
    $47,588
    good price
    $1,523 below market
    • 21,475 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Woodland Hills (374 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Woodland Hills, CA / 374 miles away from Reno, NV

    450h ONE OWNER, PREMIUM PACKAGE, HEATED & VENTILATED SEATS, POWER TILT-AND-SLIDE MOONROOF, BLIND SPOT MONITOR, INTUITIVE PARKING, 3.5L V6 DOHC VVT-i 2...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC079833
    Stock: T25L6884
    Certified Pre-Owned: No
    Listed since: 07-19-2025

  • Price Drop
    $22,211
    fair price
    $390 above market
    • 126,520 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 30 City / 28 Hwy MPG
    • Tim Dahle INFINITI (431 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Murray, UT / 431 miles away from Reno, NV

    Clean CARFAX One-Owner! Tim Dahle INFINITI is pleased to offer NO PAYMENTS for 60 Days on this 2016 Lexus RX 450h AWD in Matador Red Mica and is well ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    30 Combined MPG (30 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA1GC002352
    Stock: 041105A
    Certified Pre-Owned: No
    Listed since: 06-13-2025

  • Price Drop
    $47,777
    good price
    $1,478 below market
    • 21,773 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Woodland Hills (374 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Woodland Hills, CA / 374 miles away from Reno, NV

    450h AWD ONE OWNER, NAVIGATION, PREMIUM PACKAGE, HEATED & VENTILATED SEATS, PREMIUM SOUND, POWER TILT-AND-SLIDE MOONROOF, BLIND SPOT MONITOR, INTUITIV...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1NC087473
    Stock: T25L6984
    Certified Pre-Owned: No
    Listed since: 07-22-2025

  • Price Drop
    Stock photo**
    $47,500
    good price
    $2,722 below market
    • 25,487 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Thousand Oaks (372 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Thousand Oaks, CA / 372 miles away from Reno, NV

    Our wish is to engage you in a lifelong relationship, based on making the most of every moment and exceeding your expectations. every day! From the mo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2NC090379
    Stock: C090379T
    Certified Pre-Owned: Yes
    Listed since: 07-12-2025

  • Price Drop
    $46,492
    good price
    $1,905 below market
    • 26,068 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Capistrano Valley Toyota (433 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in San Juan Capistrano, CA / 433 miles away from Reno, NV

    **CAPISTRANO VALLEY TOYOTA SPOTLIGHT**, 3.5L V6 DOHC VVT-i 24V, AWD, Parchment w/NuLuxe Seat Trim.Clean CARFAX.Odometer is 1101 miles below market ave...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA3NC077995
    Stock: 25C2256A
    Certified Pre-Owned: No
    Listed since: 07-01-2025

    • 29,876 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from TX to NV*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Corpus Christi, TX / 1,526 miles away from Reno, NV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0NC077999
    Stock: 26403175
    Certified Pre-Owned: No

    • 29,821 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 1,366 miles away from Reno, NV

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC081163
    Stock: 2003713293
    Certified Pre-Owned: No
    Listed since: 05-07-2025

    • 52,394 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 1,366 miles away from Reno, NV

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA8NC086742
    Stock: 2003874190
    Certified Pre-Owned: No
    Listed since: 07-14-2025

  • $43,998
    fair price
    $1,485 below market
    • 40,485 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from PA to NV*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Mechanicsburg, PA / 2,252 miles away from Reno, NV

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC092307
    Stock: 27459841
    Certified Pre-Owned: No

  • $31,990
    fair price
    $690 below market
    • 54,520 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Phoenix, AZ / 597 miles away from Reno, NV

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA4JC027091
    Stock: 2003760618
    Certified Pre-Owned: No
    Listed since: 05-24-2025

  • $51,999
    fair price
    $1,348 above market
    • 26,302 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Serramonte (186 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Colma, CA / 186 miles away from Reno, NV

    $2,542 below KBB Retail! Only 26,302 Miles! Scores 28 Highway MPG and 31 City MPG! Carfax One-Owner Vehicle. Dealer Certified Pre-Owned. This Lexus RX...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA3NC083859
    Stock: SNC083859
    Certified Pre-Owned: No
    Listed since: 05-20-2025

  • Price Drop
    $49,491
    fair price
    $1,430 above market
    • 21,245 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Thousand Oaks (372 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Thousand Oaks, CA / 372 miles away from Reno, NV

    Step into the SoCal lifestyle with the 2022 Lexus RX 450h, where every drive is a perfect mix of luxury, efficiency, and the vibrant energy of the Gol...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC083367
    Stock: C083367T
    Certified Pre-Owned: Yes
    Listed since: 07-14-2025

  • $46,595
    fair price
    $124 above market
    • 30,091 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Land Rover Thousand Oaks (372 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Thousand Oaks, CA / 372 miles away from Reno, NV

    Step into the world of luxury and innovation with the 2022 Lexus RX 450h, where every drive through the sun-soaked streets of Southern California beco...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC092511
    Stock: C092511T
    Certified Pre-Owned: No
    Listed since: 07-13-2025

    • 33,555 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Motor City Lexus of Bakersfield (292 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Bakersfield, CA / 292 miles away from Reno, NV

    This 2022 Lexus RX RX 450h F SPORT Handling, has a ATOMIC SILVER exterior and an CIRCUIT RED interior color. 33555 miles. Stock Number X162682. You ca...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA0NC075119
    Stock: X162682
    Certified Pre-Owned: Yes
    Listed since: 07-15-2025

  • $23,888
    fair price
    $375 below market
    • 108,359 miles
    • 2 accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Culver City Toyota (386 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Culver City, CA / 386 miles away from Reno, NV

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA5JC026287
    Stock: T32187Q
    Certified Pre-Owned: No
    Listed since: 05-12-2025

  • $45,588
    fair price
    $1,642 above market
    • 32,982 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Woodland Hills (374 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Woodland Hills, CA / 374 miles away from Reno, NV

    450h ONE OWNER, HEATED & VENTILATED SEATS, POWER TILT-AND-SLIDE MOONROOF, BLIND SPOT MONITOR, INTUITIVE PARKING, ILLUMINATED DOOR SILLS, HEATED LEATHE...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC087123
    Stock: B4194
    Certified Pre-Owned: No
    Listed since: 07-14-2025

  • $47,415
    fair price
    $123 above market
    • 48,029 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Pleasanton (163 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Pleasanton, CA / 163 miles away from Reno, NV

    RX 450h trim. CARFAX 1-Owner, L/ Certified. EPA 28 MPG Hwy/31 MPG City! Heated Seats, NAV, Sunroof, CD Player, iPod/MP3 Input, Satellite Radio, Remote...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0NC079798
    Stock: P2637
    Certified Pre-Owned: Yes
    Listed since: 07-11-2025

  • Price Drop
    $41,472
    fair price
    $1,491 below market
    • 33,789 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Bloomfield, NJ / 2,388 miles away from Reno, NV

    CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,L...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC084311
    Stock: BBP10008
    Certified Pre-Owned: No

  • $31,000
    fair price
    $443 above market
    • 71,987 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Garden Grove Hyundai (409 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Garden Grove, CA / 409 miles away from Reno, NV

    2018 Lexus RX White eCVT Backup Camera, Blind Spot Monitoring, Bluetooth, Dual Powered Seats, Heated Seats, Keyless Entry, Leather Seats, Navigation S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA9JC028561
    Stock: PG10297
    Certified Pre-Owned: No
    Listed since: 07-22-2025

  • $32,992
    fair price
    $425 below market
    • 44,551 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Fiuza Motors (430 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Midvale, UT / 430 miles away from Reno, NV

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA2JC029518
    Stock: L1029518
    Certified Pre-Owned: No
    Listed since: 12-23-2024

  • $33,995
    good price
    $918 below market
    • 101,197 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Clear Choice Automotive (432 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Milwauikie, OR / 432 miles away from Reno, NV

    1 OWNER, VERY CLEAN, FULLY LOADED, CLEAN TITLE, APPLY ONLINE, LOOKS AND DRIVES GREAT.... DON'T MISS OUT........ CLEARCHOICEAUTOMOTIVE.COM _____APPLY O...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC094131
    Stock: 094131
    Certified Pre-Owned: No
    Listed since: 04-17-2025

Showing 127 - 147 out of 273 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (15%)
  • 3 star
    (12%)
  • 2 star
    (3%)
  • 1 star
    (3%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2022 Lexus RX 450h in Reno, NV Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$34,580$36,112$37,708
Clean$34,120$35,611$37,166
Average$33,352$34,778$36,262
Rough$32,353$33,694$35,087

The average list price of a used 2022 Lexus RX 450h in Reno, Nevada is $42,033. The average mileage on a used Lexus RX 450h 2022 for sale in Reno, Nevada is 46,691. Based on the average mileage of 46,691 for used 2022 Lexus RX 450h for sale in Reno, NV and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Reno, Nevada to be $33,352.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.