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393 listings
    • 68,345 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tom Roush Lincoln (377 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fishers, IN / 377 miles away from Roanoke, VA

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V **ONE OWNER**, **NO ACCIDENTS**, **LEATHER SEATS**, **PANORAMIC SUNROOF/MOONROOF*...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC083161
    Stock: L25096A
    Certified Pre-Owned: No
    Listed since: 05-31-2025

  • New Listing
    Stock photo**
    • 32,057 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lindsay Lexus of Alexandria (189 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Alexandria, VA / 189 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA8NC093352
    Stock: LP17989A
    Certified Pre-Owned: No
    Listed since: 06-11-2025

    • 71,274 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • TJ Auto (395 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Brooklyn, NY / 395 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC084536
    Stock: 084536
    Certified Pre-Owned: No
    Listed since: 01-17-2025

  • Stock photo**
    • 20,254 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Burdick Lexus (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cicero, NY / 454 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1NC088817
    Stock: 1C51761D
    Certified Pre-Owned: No
    Listed since: 06-02-2025

    • 60,480 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • New Motors Subaru (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Erie, PA / 329 miles away from Roanoke, VA

    Certification Program Details: * 24 Month/24,000 Mile Powertrain Warranty * Free State Inspections For LIfe * Free Carfax History Report * Full Tank O...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7LC054457
    Stock: 42419A
    Certified Pre-Owned: No
    Listed since: 05-14-2025

  • New Listing
    Stock photo**
    • 31,654 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Craig and Landreth Cars (318 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Louisville, KY / 318 miles away from Roanoke, VA

    We're Kentuckiana's premier pre-owned dealership! Having been in business for nearly 50 years, we've built our reputation providing the cleanest vehic...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC093499
    Stock: D46790
    Certified Pre-Owned: No

  • Stock photo**
    • 30,126 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Preston Hyundai of Millsboro (269 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Millsboro, DE / 269 miles away from Roanoke, VA

    3.5L V6 DOHC VVT-i 24V, AWD. 2022 Lexus RX 450h Recent Arrival! 31/28 City/Highway MPG 3.5L V6 DOHC VVT-i 24V SilverWE ARE OPEN FOR ALL YOUR SALES AND...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA8NC082725
    Stock: DXHM086A
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • New Listing
    • 37,569 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Flow Acura of Winston-Salem (85 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Winston Salem, NC / 85 miles away from Roanoke, VA

    FLOW CERTIFIED!! 48 MONTH/100 000 WARRANTY!! 2 YEAR/24000 MILES COMPLIMENTARY MAINTENANCE 3 DAY/300 MILE MONEY BACK GUARANTEE CLEAN CARFAX - NO ACCIDE...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA8MC060348
    Stock: V13098B
    Certified Pre-Owned: No
    Listed since: 06-03-2025

  • New Listing
    • 27,081 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Keyless Entry/Start
    Close

    Located in Sacramento, CA / 2,245 miles away from Roanoke, VA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6MC064382
    Stock: 2003792361
    Certified Pre-Owned: No
    Listed since: 06-13-2025

    • 33,445 miles
    • 1 accident, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Car Town Kia USA (255 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Nicholasville, KY / 255 miles away from Roanoke, VA

    Summary2020 Lexus RX 350 AWD Luxury, Reliability, and Value!Experience the perfect blend of comfort, performance, and peace of mind with this stunning...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6LC049153
    Stock: 15954
    Certified Pre-Owned: No
    Listed since: 05-24-2025

  • Price Drop
    Stock photo**
    • 37,331 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Burlington Chrysler Dodge Jeep Ram (334 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Burlington, NJ / 334 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC081249
    Stock: PJ0932
    Certified Pre-Owned: No
    Listed since: 05-14-2025

    • 50,996 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hendrick Lexus Charleston (310 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Charleston, SC / 310 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1MC059347
    Stock: SA14906
    Certified Pre-Owned: No
    Listed since: 12-24-2024

    • 67,630 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Grand Motorcars Kennesaw (344 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Kennesaw, GA / 344 miles away from Roanoke, VA

    Vehicle Overview 3.5L V6 DOHC VVT-i 24V, AWD, Circuit Red Artificial Leather, Accessory Package, Black Outer Mirrors, Black Wheel Locks, Cargo Net, Ca...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA5NC087918
    Stock: NC087918
    Certified Pre-Owned: No
    Listed since: 04-27-2025

  • New Listing
    • 26,020 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Easterns Automotive Group of Temple Hills (195 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Temple Hills, MD / 195 miles away from Roanoke, VA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC077542
    Stock: 162945
    Certified Pre-Owned: No

  • New Listing
    Stock photo**
    • 46,421 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Greenville (216 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Keyless Entry/Start
    Close

    Located in Greenville, SC / 216 miles away from Roanoke, VA

    Heated/Cooled Seats, Moonroof, Navigation, Heated Rear Seat, Power Liftgate, All Wheel Drive, Aluminum Wheels, 12.3 NAVIGATION SYSTEM W/MARK LEVINS......

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDAXMC071898
    Stock: AMC071898
    Certified Pre-Owned: No
    Listed since: 06-02-2025

Showing 379 - 393 out of 393 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.6 out of 5 stars47 Reviews
Write a vehicle reviewSee all 47 reviews
  • 5 star
    (81%)
  • 4 star
    (11%)
  • 3 star
    (4%)
  • 2 star
    (2%)
  • 1 star
    (2%)
4 out of 5 stars

Very pleased with this car after nearly 8 years!

Happy Lexus Owner, 04/08/2018
2010 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
We bought our RX450h new and have driven it daily since. It is not a car for the performance oriented driver. It is a room, comfortable cruiser that gets impressive gasoline mileage in town. On the highway it is smooth and quiet. The hybrid drive has worked great, and we've had no problems with the system. After 70K miles, I can report only one significant mechanical problem, which could … very well have been catastrophic. An oil hose burst and the car leaked oil all over our garage a driveway. Fortunately, I discovered it in time before the car was driven a significant distance. The local Lexus dealer replaced it for free. This was not an isolated incident with the model... there are quite a few similar cases posted on internet forums. Why the Lexus dealer didn't recall and replace it earlier is a mystery. If you own this car or buy one used, make sure your mechanic checks all of the oil hoses! Otherwise, it's a great (if boring) car. We will pass it down to our teenage daughter soon.
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Used 2022 Lexus RX 450h in Roanoke, VA Values

Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$32,588$34,007$35,487
Clean$32,153$33,536$34,977
Average$31,430$32,751$34,126
Rough$30,489$31,731$33,021

The average list price of a used 2022 Lexus RX 450h in Roanoke, Virginia is $44,845. The average mileage on a used Lexus RX 450h 2022 for sale in Roanoke, Virginia is 42,712. Based on the average mileage of 42,712 for used 2022 Lexus RX 450h for sale in Roanoke, VA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Roanoke, Virginia to be $31,430.

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