Purchased this after totaling a S Class. The RX350 is no S class, but it's a fine vehicle, dependable, quiet, buttons laid out nice. the drive is solid, but it's not a drivers car, the feel is muted and bland. GPS is great (except you can't change it while driving), stock stereo is not up to par with Benz or Acura. Mileage is truly impressive, if you go the speed limit you get 29 MPG highway! what is disappointing is the "luxury" aspect, the vinyl door inserts instead of leather, a known and persistent rattle from back, no push button start and no aux in. It feels like a luxury car for the masses (which is exactly what it is I guess).
fold down armrest, comfortable seat, gps is great, awd is nice, the maint. is very reasonable.
stock stereo is terrible, plan on spending $1000 to upgrade. a couple of blind spots, worst thing is the damn rattle from the trunk!