Skip to main content
Skip to Filters
2,969 listings
  • New Listing
    • 32,390 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from MS to SC*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Biloxi, MS / 631 miles away from Myrtle Beach, SC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAA3MC191462
    Stock: 27513892
    Certified Pre-Owned: No

    • 29,332 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • Morris Auto Sales GA (352 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Carrollton, GA / 352 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA1MC266864
    Stock: 14245
    Certified Pre-Owned: No
    Listed since: 07-16-2025

  • Price Drop
    • 36,791 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 22 City / 29 Hwy MPG
    • Hennessy Lexus of Gwinnett (298 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Duluth, GA / 298 miles away from Myrtle Beach, SC

    Hennessy Lexus of Gwinnett is proud to offer you this Exceptional 2023 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA9P2002149
    Stock: G3884P
    Certified Pre-Owned: Yes
    Listed since: 05-15-2025

    • 39,046 miles
    • No accidents, 2 owners, rental vehicle
    • 5 Seats, 21 City / 28 Hwy MPG
    • Stearns Ford (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Burlington, NC / 170 miles away from Myrtle Beach, SC

    2023 Lexus RX 350 PremiumPOWER LIFTGATE, BACK UP CAMERA, NAVIGATION SYSTEM, REMOTE KEYLESS ENTRY, WIRLESS CHARGING, APPLE CARPLAY, HEATED FRONT SEATS,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXPC020110
    Stock: 4391A
    Certified Pre-Owned: No
    Listed since: 07-12-2025

    • 15,198 miles
    • No accidents, 1 owner, personal use
    • Auto Lenders of Egg Harbor Township (466 mi away)
    Close

    Located in Egg Harbor, NJ / 466 miles away from Myrtle Beach, SC

    CertificationThis Auto Lenders Certified 2023 Lexus RX 350 Premium has passed our rigorous 110 pt inspection. All Auto Lenders Certified cars are guar...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 2T2BAMCA0PC026563
    Stock: PC026563
    Certified Pre-Owned: No
    Listed since: 07-12-2025

    • 35,559 miles
    • No accidents, 1 owner, personal use only
    • Melbourne BMW (397 mi away)
    • Back-Up Camera
    • Blind Spot Monitor
    • Adaptive Cruise Cont...
    • Bluetooth Connection
    • Navigation System
    Close

    Located in Melbourne, FL / 397 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 2T2BAMCA6PC017656
    Stock: B17897A
    Certified Pre-Owned: No
    Listed since: 06-29-2025

  • New Listing
    • 118,317 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Volvo Cars Greenville (210 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Greenville, SC / 210 miles away from Myrtle Beach, SC

    Call 8**-2**-8*** and ask for VW Sales for more information! *All prices exclude IMF, applicable taxes, tag, title, registration and $499 closing fees...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2JZMDAXMC271725
    Stock: P8886
    Certified Pre-Owned: No
    Listed since: 07-09-2025

    • 37,111 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Mike Erdman Toyota (382 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cocoa, FL / 382 miles away from Myrtle Beach, SC

    BLUETOOTH, REAR BACK UP CAMERA, APPLE/ANDROID CAR PLAY, BLIND SPOT MONORITING, LANE DEPARTURE WARNING, LEATHER SEATING, HEATED SEATS, MOONROOF, LOCAL ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA2MC291286
    Stock: 101019C
    Certified Pre-Owned: No
    Listed since: 07-19-2025

  • Price Drop
    • 36,034 miles
    • No accidents, 1 owner, personal use only
    • Lexus of Sarasota (489 mi away)
    • Leather Seat Trim
    • Heated front seats
    • Power moonroof
    • Remote keyless entry
    • Heated door mirrors
    Close

    Located in Sarasota, FL / 489 miles away from Myrtle Beach, SC

    **LEXUS L/CERTIFIED VEHICLE * 6 YEARS UNLIMITED MILEAGE FACTORY WARRANTY** Clean CARFAX. CARFAX One-Owner. Birch w/Black Open Pore w/Leather Seat Trim...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: JTJCHMAA3P2006312
    Stock: C089969A
    Certified Pre-Owned: Yes
    Listed since: 05-20-2025

  • New Listing
    • 97,425 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Driver's Way Hwy 280 (445 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Birmingham, AL / 445 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA6KC123248
    Stock: D65068
    Certified Pre-Owned: No
    Listed since: 07-08-2025

    • 41,702 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 21 City / 28 Hwy MPG
    • Hennessy Lexus of Atlanta (307 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Atlanta, GA / 307 miles away from Myrtle Beach, SC

    Hennessy Lexus of Atlanta is proud to offer you this Exceptional 2023 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a r...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6PC010674
    Stock: A5090P
    Certified Pre-Owned: Yes
    Listed since: 05-06-2025

    • 97,373 miles
    • No accidents, 2 owners, rental vehicle
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Knoxville (333 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Knoxville, TN / 333 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA0KC118210
    Stock: 2302A
    Certified Pre-Owned: No
    Listed since: 07-12-2025

    • 38,810 miles
    • No accidents, 1 owner, personal use only
    • Private Allstar Cars (459 mi away)
    Close

    Located in Largo, FL / 459 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 2T2BAMBA6PC006805
    Stock: 006805
    Certified Pre-Owned: No
    Listed since: 03-13-2025

    • 6,500 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NY to SC*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Albany, NY / 685 miles away from Myrtle Beach, SC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3PC029912
    Stock: 27311531
    Certified Pre-Owned: No

    • 46,315 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Autoplex Atlanta (298 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Duluth, GA / 298 miles away from Myrtle Beach, SC

    Vehicle Overview 2023 Lexus RX 350 F Sport Handling Blue AWD 8-Speed Automatic 2.4L I4 PDI Turbocharged DOHC 16V LEV3-SULEV30 275hp AWD, Black Artific...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3PC010132
    Stock: PC010132
    Certified Pre-Owned: No
    Listed since: 03-31-2025

    • 73,749 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Signal Imports (197 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Spartanburg, SC / 197 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAAXMC186435
    Stock: 186435
    Certified Pre-Owned: No
    Listed since: 05-31-2025

  • New Listing
    Stock photo**
    • 20,365 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Cherry Hill (486 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Mount Laurel, NJ / 486 miles away from Myrtle Beach, SC

    Lexus Certified 161-Point Inspection., LEATHER, MOONROOF, BLUETOOTH HANDSFREE PHONE, BACK-UP CAMERA, ALL WHEEL DRIVE, CLEAN CAR FAX, LOCAL TRADE, AWD,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA9MC308262
    Stock: N53395A
    Certified Pre-Owned: Yes
    Listed since: 07-23-2025

    • 41,571 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Brambleton Imports (255 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Roanoke, VA / 255 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2MC202837
    Stock: 202837
    Certified Pre-Owned: No
    Listed since: 04-07-2025

  • Price Drop
    • 44,281 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Las Vegas, NV / 2,047 miles away from Myrtle Beach, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2AZMDA2MC268320
    Stock: 2003850426
    Certified Pre-Owned: No
    Listed since: 07-01-2025

    • 75,808 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Performance Lexus Northern Kentucky (486 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Wright, KY / 486 miles away from Myrtle Beach, SC

    This 2021 Lexus Rx 350 is loaded with convenient features like: AWD, Premium Package, Cold Area Package, Backup Cam, Nuluxe Trim, Heated Seats, Apple ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA8MC269258
    Stock: MC269258
    Certified Pre-Owned: No
    Listed since: 06-06-2025

  • Price Drop
    • 21,926 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Chattanooga (369 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Chattanooga, TN / 369 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA8MC218069
    Stock: 218069LP
    Certified Pre-Owned: Yes
    Listed since: 06-05-2025

Showing 1,072 - 1,092 out of 2,969 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
4.2 out of 5 stars44 Reviews
Write a vehicle reviewSee all 44 reviews
  • 5 star
    (66%)
  • 4 star
    (11%)
  • 3 star
    (7%)
  • 2 star
    (5%)
  • 1 star
    (11%)
1 out of 5 stars

Exhaust drones/vibrates between 1400/1900 RPM

AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Report abuse

Used 2021 Lexus RX 350 in Myrtle Beach, SC Values

Estimated values
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$29,352$31,426$33,502
Clean$28,894$30,927$32,961
Average$28,129$30,095$32,060
Rough$27,136$29,014$30,889

The average list price of a used 2021 Lexus RX 350 in Myrtle Beach, South Carolina is $43,307. The average mileage on a used Lexus RX 350 2021 for sale in Myrtle Beach, South Carolina is 46,933. Based on the average mileage of 46,933 for used 2021 Lexus RX 350 for sale in Myrtle Beach, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2021 in Myrtle Beach, South Carolina to be $28,129.

Filters
Skip to Results

Applied Filters4Active

Select Buying Experience

Location

Search radius500 miles
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Body Type

Trim

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details


* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.