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2,955 listings
  • New Listing
    $38,885
    fair price
    $847 above market
    • 62,195 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Ferman BMW of Palm Harbor (447 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Palm Harbor, FL / 447 miles away from Myrtle Beach, SC

    NAVIGATION*, SUNROOF*, BACK UP CAMERA*, HEATED SEATS*, BLIND SPOT MONITOR*, LANE DEPARTURE WARNING*, RX 350 F Sport Handling, 4D Sport Utility, 3.5L V...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA4NC315590
    Stock: PH13202
    Certified Pre-Owned: No
    Listed since: 04-12-2025

    • 54,843 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 20 City / 27 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in San Antonio, TX / 1,200 miles away from Myrtle Beach, SC

    CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Keyless Start,Lane Keeping Assist,Remote Start,Sate...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAA0NC237556
    Stock: NC237556P
    Certified Pre-Owned: No

  • New Listing
    • 29,653 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Franklin Toyota (184 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Statesboro, GA / 184 miles away from Myrtle Beach, SC

    Recent Arrival!Silver 2022 Lexus RX 350 FWD 8-Speed Automatic 3.5L V6 DOHC 24V LEATHER SEATS, POWER SEAT, REAR BACK UP CAMERA, BLUETOOTH, NAVIGATION...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAA1NC233984
    Stock: 45478A
    Certified Pre-Owned: No
    Listed since: 04-06-2025

  • New Listing
    $41,998
    fair price
    $448 above market
    • 22,571 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to SC*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Bakersfield, CA / 2,270 miles away from Myrtle Beach, SC

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA5NC244971
    Stock: 27405646
    Certified Pre-Owned: No

    • 29,705 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Sports & Imports (196 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Spartanburg, SC / 196 miles away from Myrtle Beach, SC

    Introducing the luxurious and powerful 2022 Lexus RX 350 Base, equipped with a 3.5L V6 engine that delivers an impressive 295 horsepower and 267 ft. l...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2NC245365
    Stock: NC245365
    Certified Pre-Owned: No
    Listed since: 07-09-2025

    • 15,581 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Bobby Rahal Lexus (467 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Mechanicsburg, PA / 467 miles away from Myrtle Beach, SC

    Recent Arrival!LOCAL ONE OWNER LEXUS TRADE IN! BOUGHT FROM US AND SERVICED WITH US! SOME Luxury options are, 12.3 Navigation System w/Mark Levinson Au...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2JZMDA7NC354241
    Stock: LX30376A
    Certified Pre-Owned: No
    Listed since: 07-11-2025

  • $41,500
    fair price
    $493 above market
    • 36,808 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Sam Boswell Honda (433 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Enterprise, AL / 433 miles away from Myrtle Beach, SC

    Recent Arrival!Every Pre-Owned vehicle at Sam Boswell Honda comes with a Limited 3 Month / 3,000 Mile Powertrain Warranty, covering up to $1,000.2022 ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA4NC228941
    Stock: SW16775
    Certified Pre-Owned: No
    Listed since: 07-10-2025

    • 23,462 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Radley Cadillac (329 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fredericksburg, VA / 329 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA9NC254595
    Stock: CAP5132
    Certified Pre-Owned: No
    Listed since: 06-11-2025

  • New Listing
    $34,972
    fair price
    $1,101 above market
    • 79,838 miles
    • 5 Seats, 19 City / 26 Hwy MPG
    • Renaldo Honda (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Keyless Entry/Start
    Close

    Located in Shelby, NC / 182 miles away from Myrtle Beach, SC

    2020 Lexus RX 350 F Sport ObsidianAWD, Circuit Red Artificial Leather.19/26 City/Highway MPGProudly Serving: Shelby. Gastonia, Charlotte, Ashevi...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDA7LC227443
    Stock: PH1668
    Certified Pre-Owned: No
    Listed since: 07-21-2025

    • 32,056 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Cherry Hill (486 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Mount Laurel, NJ / 486 miles away from Myrtle Beach, SC

    Lexus Certified 161-Point Inspection., LEATHER, CLEAN CAR FAX, FULLY LOADED, AWD, Birch Leather. Recent Arrival! CARFAX One-Owner. Clean CARFAX. 2022 ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2AZMDA5NC357509
    Stock: N53454A
    Certified Pre-Owned: Yes
    Listed since: 07-12-2025

  • New Listing
    • 28,178 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Mike Erdman Nissan (380 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Cocoa, FL / 380 miles away from Myrtle Beach, SC

    2022 Lexus RX Silver 350 F Sport Handling3.5L V6 DOHC 24V AWD 8-Speed AutomaticRecent Arrival! Odometer is 8183 miles below market average! 19/26 City...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA3NC353196
    Stock: N9696
    Certified Pre-Owned: No
    Listed since: 03-11-2025

    • 27,461 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Thompson Lexus Willow Grove (497 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Willow Grove, PA / 497 miles away from Myrtle Beach, SC

    At Thompson Lexus of Willow Grove, we ensure that all our vehicles are competitively priced to provide the best value in the market. We use independen...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA3NC344899
    Stock: W2260P
    Certified Pre-Owned: Yes
    Listed since: 06-19-2025

  • New Listing
    • 27,758 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Carvana - Columbus (491 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbus, OH / 491 miles away from Myrtle Beach, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA8LC257755
    Stock: 2003873180
    Certified Pre-Owned: No
    Listed since: 07-18-2025

    • 33,839 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Cherry Hill (486 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Mount Laurel, NJ / 486 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA7NC310741
    Stock: N53439A
    Certified Pre-Owned: No
    Listed since: 07-03-2025

  • Price Drop
    $54,361
    great price
    $7,874 below market
    • 13,886 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 22 City / 29 Hwy MPG
    • Harper Porsche (332 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 332 miles away from Myrtle Beach, SC

    Includes Harper Care, an Unlimited Mileage Powetrain Warranty for 60 months from the date of purchase! 2023 Lexus RX 350 Luxury in Copper Crest over B...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA6PC020056
    Stock: 2215P-1
    Certified Pre-Owned: No
    Listed since: 07-13-2025

  • New Listing
    • 30,931 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Hennessy Lexus of Atlanta (307 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Atlanta, GA / 307 miles away from Myrtle Beach, SC

    Hennessy Lexus of Atlanta is proud to offer you this Exceptional 2022 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a r...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA3NC253930
    Stock: 2251715A
    Certified Pre-Owned: No
    Listed since: 07-13-2025

  • New Listing
    • 39,103 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Audi Clearwater (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Clearwater, FL / 454 miles away from Myrtle Beach, SC

    Drive in style and confidence with this 2022 Lexus RX 350 F SPORT AWD, finished in Nightfall Mica with a sleek Black NuLuxe interior. With just 39,000...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA2NC328757
    Stock: 63P1594
    Certified Pre-Owned: No
    Listed since: 03-29-2025

  • New Listing
    • 41,361 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Toyota of Southern Maryland (348 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Lexington Park, MD / 348 miles away from Myrtle Beach, SC

    AWD, SUNROOF, CLEAN CARFAX, SIRRUS/XM RADIO, BACKUP CAMERA, ALLOY WHEELS, Bluetooth , MARYLAND STATE INSPECTED, 72 HOUR EXCHANGE POLICY, LANE ASSIST,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDA3NC310032
    Stock: U310032
    Certified Pre-Owned: No
    Listed since: 07-04-2025

  • New Listing
    $42,995
    fair price
    $565 above market
    • 48,172 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Priority Lexus Newport News (277 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Newport News, VA / 277 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA0NC359926
    Stock: PLN21199
    Certified Pre-Owned: Yes
    Listed since: 06-19-2025

  • New Listing
    Stock photo**
    • 14,100 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Greenville (210 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Greenville, SC / 210 miles away from Myrtle Beach, SC

    Eminent White Pearl exterior and BLACK interior. Moonroof, CD Player, iPod/MP3 Input, Satellite Radio, Power Liftgate, Back-Up Camera, TILT & SLIDE MO...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAAXNC256582
    Stock: ANC256582
    Certified Pre-Owned: No
    Listed since: 07-15-2025

  • New Listing
    • 30,042 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Genesis of Columbus (494 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbus, OH / 494 miles away from Myrtle Beach, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2AZMDA3NC327232
    Stock: G462
    Certified Pre-Owned: No
    Listed since: 06-04-2025

Showing 673 - 693 out of 2,955 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
4.2 out of 5 stars44 Reviews
Write a vehicle reviewSee all 44 reviews
  • 5 star
    (66%)
  • 4 star
    (11%)
  • 3 star
    (7%)
  • 2 star
    (5%)
  • 1 star
    (11%)
1 out of 5 stars

Exhaust drones/vibrates between 1400/1900 RPM

AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
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Used 2022 Lexus RX 350 in Myrtle Beach, SC Values

Estimated values
2022 Lexus RX 350 F SPORT 4dr SUV AWD w/Handling Package (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$36,859$39,448$42,148
Clean$36,368$38,902$41,542
Average$35,550$37,991$40,532
Rough$34,486$36,807$39,219

The average list price of a used 2022 Lexus RX 350 in Myrtle Beach, South Carolina is $44,314. The average mileage on a used Lexus RX 350 2022 for sale in Myrtle Beach, South Carolina is 34,359. Based on the average mileage of 34,359 for used 2022 Lexus RX 350 for sale in Myrtle Beach, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Myrtle Beach, South Carolina to be $35,550.

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