Skip to FiltersReport abuse
3,014 listings
- New Listing$34,900good price$1,770 below market
- 93,989 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Mercedes-Benz of Winston-Salem (185 mi away)
Close
Located in Winston Salem, NC / 185 miles away from Myrtle Beach, SC
Clean CARFAX.Mercedes-Benz of Winston Salem is proud to present you with another True Market Priced Pre-Owned Vehicle. This 2022 Lexus RX 350 is loade...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTJHZMDA0N2059030
Stock: P10008A
Certified Pre-Owned: No
Listed since: 06-18-2025 - $41,998good price$1,790 below market
- 36,591 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Greenville (210 mi away)
Close
Located in Greenville, SC / 210 miles away from Myrtle Beach, SC
Heated/Cooled Seats, Nav System, Satellite Radio, Power Liftgate, All Wheel Drive, ACCESSORY PACKAGE, INTUITIVE PARKING ASSIST W/PANORAMIC.. 12.3 NAVI...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDAXNC312581
Stock: ANC312581
Certified Pre-Owned: Yes
Listed since: 05-03-2025 - New Listing$46,770fair price$1,052 below market
- 11,508 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lindsay Lexus of Alexandria (372 mi away)
Close
Located in Alexandria, VA / 372 miles away from Myrtle Beach, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC334428
Stock: L49272A
Certified Pre-Owned: Yes
Listed since: 04-29-2025 - New Listing$41,260fair price$1,040 below market
- 34,749 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Rick Hendrick Chevrolet (298 mi away)
Close
Located in Duluth, GA / 298 miles away from Myrtle Beach, SC
2022 Lexus RX 350 5-DOOR SUV 4X2 --- Exceptional Luxury Meets Advanced PerformanceDiscover the perfect blend of sophistication, comfort, and cutting-e...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC246048
Stock: S59654B
Certified Pre-Owned: No
Listed since: 05-15-2025 - $39,590fair price
- 43,876 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Dallas, TX / 1,031 miles away from Myrtle Beach, SC
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC243828
Stock: 2003846912
Certified Pre-Owned: No
Listed since: 07-04-2025 - $43,989fair price$251 below market
- 19,199 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Jarrett Ford (413 mi away)
Close
Located in Dade City, FL / 413 miles away from Myrtle Beach, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC258114
Stock: 250391A
Certified Pre-Owned: No
Listed since: 05-27-2025 - New Listing$36,590good price$1,223 below market
- 36,807 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana - Charlotte (152 mi away)
- Home delivery*
Close
Located in Charlotte, NC / 152 miles away from Myrtle Beach, SC
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXLC156480
Stock: 2003834748
Certified Pre-Owned: No
Listed since: 06-28-2025 - New Listing$39,800good price$2,869 below market
- 28,804 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Safford Alfa Romeo of Tysons Corner (376 mi away)
Close
Located in Vienna, VA / 376 miles away from Myrtle Beach, SC
CARFAX One-Owner. Mica 2022 Lexus RX 350 VERY WELL MAINTAINED, AWD, Glazed Caramel Artificial Leather, 3.33 Axle Ratio, 4-Wheel Disc Brakes, Alloy whe...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC325478
Stock: P2963
Certified Pre-Owned: No
Listed since: 05-01-2025 - Price Drop$42,888good price$1,655 below market
- 32,682 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Hennessy Lexus of Gwinnett (298 mi away)
Close
Located in Duluth, GA / 298 miles away from Myrtle Beach, SC
Hennessy Lexus of Gwinnett is proud to offer you this Exceptional 2022 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC227726
Stock: G3858P
Certified Pre-Owned: Yes
Listed since: 04-27-2025 - $45,888good price$1,816 below market
- 34,712 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Hennessy Lexus of Gwinnett (298 mi away)
Close
Located in Duluth, GA / 298 miles away from Myrtle Beach, SC
Hennessy Lexus of Gwinnett is proud to offer you this Exceptional 2022 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC251503
Stock: G3968P
Certified Pre-Owned: Yes
Listed since: 07-08-2025 - New Listing$46,151fair price$1,346 below market
- 36,994 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Hendrick Lexus (147 mi away)
Close
Located in Charlotte, NC / 147 miles away from Myrtle Beach, SC
L/ Certified: 2-YEAR Unlimited Mileage WARRANTY INCLUDED. Complimentary Maintenance for 20,000 Miles! Sunroof, Heated Seats, NAV, Power Liftgate, Sate...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC251670
Stock: PGA45A
Certified Pre-Owned: Yes
Listed since: 06-12-2025 - $42,890good price$1,582 below market
- 37,627 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Mazda of Greenville (210 mi away)
Close
Located in Greenville, SC / 210 miles away from Myrtle Beach, SC
2022 Lexus RX 350 Fully Serviced, Navigation / NAV / GPS, Android Auto, Bluetooth Hands-Free, Apple CarPlay, Back Up Camera, Blind Spot Monitoring, US...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC258628
Stock: 2521602A
Certified Pre-Owned: No
Listed since: 06-09-2025 - $44,495fair price$451 below market
- 27,928 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Sports & Imports (196 mi away)
Close
Located in Spartanburg, SC / 196 miles away from Myrtle Beach, SC
**One Owner **Clean Carfax ** Southern Vehicle **Just Serviced**Michelin Tires**Connected Navigation **Premium Pkg**Moonroof**Heated & Cooled Seats**H...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA0NC225891
Stock: NC225891
Certified Pre-Owned: No
Listed since: 02-14-2025 - New Listing$43,000good price$1,928 below market
- 19,208 miles
- No accidents, 3 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Orlando (387 mi away)
Close
Located in Orlando, FL / 387 miles away from Myrtle Beach, SC
JUST TRADED IN, SPOTLESS CARFAX HISTORY, LOADED, NAVIGATION SYSTEM, PREMIUM PACKAGE, 20" ALLOY WHEELS, PANORAMIC VIEW MONITOR, POWER REAR DOOR W/KICK ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC229629
Stock: NC229629
Certified Pre-Owned: Yes
Listed since: 07-08-2025 - New Listing$41,995fair price$1,656 below market
- 20,774 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Ramsey, NJ / 576 miles away from Myrtle Beach, SC
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Ste...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC352574
Stock: SU031520A
Certified Pre-Owned: No - New Listing$40,250good price$1,403 below market
- 44,223 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Deacon Jones Chevrolet of La Grange (131 mi away)
Close
Located in La Grange, NC / 131 miles away from Myrtle Beach, SC
CARFAX One-Owner. White 2022 Lexus RX 350 3.5L V6 DOHC 24V 8-Speed Automatic AWD AWD, Parchment w/NuLuxe Seat Trim, 3.33 Axle Ratio, 9 Speakers, AM/FM...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC310868
Stock: K550092A
Certified Pre-Owned: No
Listed since: 05-14-2025 - Price Drop$42,500fair price$13 below market
- 34,828 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lake Norman Chrysler Jeep Dodge Ram (167 mi away)
Close
Located in Cornelius, NC / 167 miles away from Myrtle Beach, SC
**Certified! *One-Owner* 2022 Lexus RX 350 FWD w/ *Clean CARFAX*, Heated and Vented Leather Seats, Heated Steering Wheel, Wireless Charging, Power Sun...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC249602
Stock: 2LN1921
Certified Pre-Owned: No
Listed since: 03-24-2025 - Price Drop$29,997good price$1,228 below market
- 91,920 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Chrysler Jeep Dodge Ram Asheville (248 mi away)
Close
Located in Asheville, NC / 248 miles away from Myrtle Beach, SC
2020 Lexus RX 350 3.5L V6 DOHC 24V AWD3.329 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, Air Conditioning, AM/FM radio: SiriusXM, Apple CarPlay/Andro...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1LC238688
Stock: C5836RT
Certified Pre-Owned: No
Listed since: 06-10-2025 - New Listing$41,470good price$1,911 below market
- 41,215 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Team One Chevrolet of Gadsden (405 mi away)
Close
Located in Gadsden, AL / 405 miles away from Myrtle Beach, SC
Recent Arrival! 20/27 City/Highway MPG LEATHER, LOADED, NAVIGATION, POWER SUNROOF, BACKUP CAMERA, ALLOY WHEELS, POWER LOCKS, HEATED SEATS, BALANCE OF ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC237845
Stock: NC237845
Certified Pre-Owned: No
Listed since: 06-07-2025 - Price Drop$43,888fair price$471 below market
- 26,061 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Hennessy Lexus of Gwinnett (298 mi away)
Close
Located in Duluth, GA / 298 miles away from Myrtle Beach, SC
Hennessy Lexus of Gwinnett is proud to offer you this Exceptional 2022 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC252693
Stock: G3839P
Certified Pre-Owned: No
Listed since: 04-14-2025 - Price Drop$44,998fair price$20 below market
- 27,119 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Greenville (210 mi away)
Close
Located in Greenville, SC / 210 miles away from Myrtle Beach, SC
Heated Seats, Moonroof, Power Liftgate, CD Player, iPod/MP3 Input, Satellite Radio, Back-Up Camera, TILT & SLIDE MOONROOF, INTUITIVE PARKING ASSIST & ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC248222
Stock: ANC248222
Certified Pre-Owned: Yes
Listed since: 06-03-2025
Showing 484 - 504 out of 3,014 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Exhaust drones/vibrates between 1400/1900 RPM
AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Used 2022 Lexus RX 350 in Myrtle Beach, SC Values
Estimated values
2022 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,406 | $35,855 | $38,408 |
| Clean | $32,961 | $35,358 | $37,856 |
| Average | $32,219 | $34,530 | $36,935 |
| Rough | $31,255 | $33,454 | $35,739 |
The average list price of a used 2022 Lexus RX 350 in Myrtle Beach, South Carolina is $41,681. The average mileage on a used Lexus RX 350 2022 for sale in Myrtle Beach, South Carolina is 37,182. Based on the average mileage of 37,182 for used 2022 Lexus RX 350 for sale in Myrtle Beach, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Myrtle Beach, South Carolina to be $32,219.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.