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1,133 listings
- $44,176fair price$77 below market
- 30,039 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- AutoCenters Nissan (490 mi away)
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Located in Herculaneum, MO / 490 miles away from Sioux Falls, SD
ONE OWNER with ZERO ACCIDENTS, All Wheel Drive, RX 350 F Sport AWD - Sunroof - Htd/Cooled Leather, 4D Sport Utility, AWD, Ultra White, Circuit Red w/F...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC355116
Stock: R83930
Certified Pre-Owned: No
Listed since: 03-31-2025 - Price Drop$45,400fair price$535 above market
- 17,348 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (185 mi away)
- Home delivery*
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Located in Minnetonka, MN / 185 miles away from Sioux Falls, SD
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Ste...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC356213
Stock: S9001033A
Certified Pre-Owned: No - New Listing$42,000fair price$236 below market
- 43,953 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Napleton's Valley Hyundai (448 mi away)
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Located in Aurora, IL / 448 miles away from Sioux Falls, SD
One Owner, Clean Car Fax, 2022 Lexus RX 350 F Sport in Black, AWD, 20" x 8" Aluminum Wheels, 3.33 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, ABS bra...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC356539
Stock: KBB1636
Certified Pre-Owned: No
Listed since: 06-06-2025 - $45,990fair price$1,116 above market
- 22,024 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (494 mi away)
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Located in Merrillville, IN / 494 miles away from Sioux Falls, SD
UNLIMITED MILE COMPREHENSIVE WARRANTY THRU 12/23/2027!, PANORAMIC GLASS MOONROOF!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC326412
Stock: PM2714
Certified Pre-Owned: Yes
Listed since: 03-28-2025 - $47,940fair price$876 above market
- 21,442 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (470 mi away)
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Located in Manchester, MO / 470 miles away from Sioux Falls, SD
Panoramic View Monitor, L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Leather Seats, Backup Camera, Power Sunroof, Heated/Ventilated seats, Premi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC348067
Stock: 35372A
Certified Pre-Owned: Yes
Listed since: 05-30-2025 - New Listing$43,500fair price$258 above market
- 37,684 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Gregg Young Toyota of Columbus (148 mi away)
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Located in Columbus, NE / 148 miles away from Sioux Falls, SD
A dynamic daily driver, our Accident Free 2022 Lexus RX 350 AWD has deluxe details and a dramatic Nightfall Mica design! Motivated by a 3.5 Liter V6 d...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDA0NC309450
Stock: 14U1247
Certified Pre-Owned: No
Listed since: 06-09-2025 - 25,775 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Poquet Auto Sales (193 mi away)
Close
Located in Golden Valley, MN / 193 miles away from Sioux Falls, SD
Navigation, Moonroof, Leather, Heated & Ventilated Front Seats, Adaptive Cruise, BLIS, Lane Keep Assist, Apple CarPlay, Android Auto, 20" Alloy Wheels...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA8NC310687
Stock: 24251934
Certified Pre-Owned: No
Listed since: 04-25-2025- 26,152 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Orland (470 mi away)
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Located in Orland Park, IL / 470 miles away from Sioux Falls, SD
Nightfall Mica 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V BOUGHT HERE SERVICED HERE!, LOCAL TRADE!, ONE OWNER!, GREAT VEHICLE HISTORY!, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC338996
Stock: LX06191
Certified Pre-Owned: Yes
Listed since: 04-21-2025- $48,988good price$2,338 below market
- 23,454 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (472 mi away)
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Located in Chicago, IL / 472 miles away from Sioux Falls, SD
Recent Arrival! Nightfall Mica 2022 Lexus RX 350 F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC359984
Stock: U4729A
Certified Pre-Owned: Yes
Listed since: 06-05-2025 - Price Drop$40,499fair price$906 above market
- 38,819 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (187 mi away)
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Located in Wayzata, MN / 187 miles away from Sioux Falls, SD
Treat yourself to Lexus Certified ownership privileges:161-point inspection by expert Lexus technicians ensures exemplary condition24/7 Roadside As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3LC236148
Stock: PRS478
Certified Pre-Owned: Yes
Listed since: 06-03-2025 - $33,995good price$1,487 below market
- 80,788 miles
- 2 accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (450 mi away)
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Located in Arlington Heights, IL / 450 miles away from Sioux Falls, SD
2022 Lexus RX 350 F Sport Automatic, AWD/4WD, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for this Val...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA9NC321214
Stock: AL2136P
Certified Pre-Owned: No
Listed since: 03-31-2025 - Price Drop$42,999fair price$1,027 above market
- 42,993 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Maplewood (208 mi away)
Close
Located in Maplewood, MN / 208 miles away from Sioux Falls, SD
L/Certified by Lexus, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, Parking Assist Sensors, Pre-Collisio...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC344561
Stock: PJR19425
Certified Pre-Owned: Yes
Listed since: 05-23-2025 - New Listing$39,998fair price$299 above market
- 37,237 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax Kenosha (446 mi away)
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Located in Kenosha, WI / 446 miles away from Sioux Falls, SD
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC227394
Stock: 26911098
Certified Pre-Owned: No - Price Drop$44,970fair price$703 above market
- 17,780 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Tom Kadlec Honda (211 mi away)
Close
Located in Rochester, MN / 211 miles away from Sioux Falls, SD
Lexus RX 350 3.5L V6 DOHC 24V TRADED HERE, AWD, Parchment Artificial Leather, Air Conditioning, AM/FM radio: SiriusXM, Apple CarPlay/Android Auto, Aut...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7NC325286
Stock: P11874A
Certified Pre-Owned: No
Listed since: 05-20-2025 - Price Drop$45,986fair price$191 below market
- 18,310 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Briggs Supercenter Manhattan (303 mi away)
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Located in Manhattan, KS / 303 miles away from Sioux Falls, SD
This 2022 Lexus RX RX 350, comes in exterior with interior. 18310 miles. Stock Number ARCTB0085 Important Package InformationSafety and Security Wi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC360091
Stock: ARCTB0085
Certified Pre-Owned: No
Listed since: 05-27-2025 - $36,500fair price$268 below market
- 46,704 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (441 mi away)
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Located in Milwaukee, WI / 441 miles away from Sioux Falls, SD
Navigation system!Touch-free power rear door with kick sensor!Heated leather steering wheel!Heated and ventilated front seats!Certified. CARF...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3LC244878
Stock: PRS7985
Certified Pre-Owned: Yes
Listed since: 05-07-2025 - New Listing$42,998fair price$631 above market
- 19,978 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Oak Lawn (469 mi away)
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Located in Oak Lawn, IL / 469 miles away from Sioux Falls, SD
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA3LC233850
Stock: 26995458
Certified Pre-Owned: No - $45,990fair price$759 above market
- 30,085 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (494 mi away)
Close
Located in Merrillville, IN / 494 miles away from Sioux Falls, SD
2 YEAR/UNLIMITED MILE COMPREHENSIVE WARRANTY!, PANORAMIC VIEW MONITOR!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED STEERING W...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC358543
Stock: PM2744
Certified Pre-Owned: Yes
Listed since: 06-03-2025 - 8 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Auto Campus (404 mi away)
Close
Located in Wichita, KS / 404 miles away from Sioux Falls, SD
2022 Lexus RX 350 AWD, located at Lexus of Wichita. Original MSRP $58,115. Atomic Silver with Glazed Caramel interior. This 1 owner RX is equipped wit...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC355519
Stock: 54L1013P
Certified Pre-Owned: No
Listed since: 12-18-2024- Price Drop
- 2,839 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax St. Louis South Lindbergh (479 mi away)
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Located in Saint Louis, MO / 479 miles away from Sioux Falls, SD
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA8NC353050
Stock: 25203273
Certified Pre-Owned: No - New Listing$47,999fair price$138 above market
- 16,852 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (187 mi away)
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Located in Wayzata, MN / 187 miles away from Sioux Falls, SD
Recent Arrival! CARFAX One-Owner. Certified. Nebula Gray Pearl 2022 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V AWD 19/26 City/Highway MPG Clean CA...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC322085
Stock: PRS481
Certified Pre-Owned: Yes
Listed since: 06-12-2025
Showing 43 - 63 out of 1,133 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Sioux Falls, SD Values
Estimated values
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $39,305 | $41,764 | $44,328 |
| Clean | $38,781 | $41,185 | $43,690 |
| Average | $37,908 | $40,221 | $42,628 |
| Rough | $36,774 | $38,968 | $41,247 |
The average list price of a used 2022 Lexus RX 350 in Sioux Falls, South Dakota is $44,456. The average mileage on a used Lexus RX 350 2022 for sale in Sioux Falls, South Dakota is 28,584. Based on the average mileage of 28,584 for used 2022 Lexus RX 350 for sale in Sioux Falls, SD and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Sioux Falls, South Dakota to be $37,908.
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