Skip to FiltersReport abuse
3,001 listings
- $45,498fair price$1,579 above market
- 30,076 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- McDaniels Ford (109 mi away)
Close
Located in Orangeburg, SC / 109 miles away from Myrtle Beach, SC
Vehicle DetailsExperience luxury and performance with this exceptional 2022 Lexus RX 350! With just 30,072 miles, this sophisticated SUV is ready to e...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC235916
Stock: 81040
Certified Pre-Owned: No
Listed since: 03-24-2025 - New Listing$45,879fair price$389 above market
- 40,912 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Hendrick Lexus Charleston (87 mi away)
Close
Located in Charleston, SC / 87 miles away from Myrtle Beach, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA3NC254835
Stock: S00913A
Certified Pre-Owned: Yes
Listed since: 05-07-2025 - Price Drop$44,500fair price$882 above market
- 20,974 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Silver Spring (389 mi away)
Close
Located in Silver Spring, MD / 389 miles away from Myrtle Beach, SC
2022 Lexus RX 350 CARFAX One-Owner. Clean CARFAX.Eminent White Pearl AWD, Black Artificial Leather, 18 x 8 Aluminum Wheels, 3.33 Axle Ratio, 4-Wheel D...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC368446
Stock: P1D1615
Certified Pre-Owned: No
Listed since: 06-20-2025 - Price Drop$43,500fair price$172 above market
- 34,828 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lake Norman Chrysler Jeep Dodge Ram (167 mi away)
Close
Located in Cornelius, NC / 167 miles away from Myrtle Beach, SC
**Certified! *One-Owner* 2022 Lexus RX 350 FWD w/ *Clean CARFAX*, Heated and Vented Leather Seats, Heated Steering Wheel, Wireless Charging, Power Sun...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC249602
Stock: 2LN1921
Certified Pre-Owned: No
Listed since: 03-23-2025 - New Listing$46,588fair price$858 above market
- 22,889 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Shottenkirk's Cherokee Chrysler Dodge Jeep Ram (319 mi away)
Close
Located in Canton, GA / 319 miles away from Myrtle Beach, SC
CARFAX One-Owner. 2022 Lexus RX 350 F Sport Handling 350 F Sport Handling Gray 4D Sport Utility 3.5L V6 DOHC 24V 8-Speed Automatic AWD This vehicle co...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA1NC334503
Stock: U23128
Certified Pre-Owned: No
Listed since: 02-06-2025 - $41,695fair price$164 below market
- 17,039 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Delray Auto Mall (500 mi away)
Close
Located in Delray Beach, FL / 500 miles away from Myrtle Beach, SC
Leather Interior. Burlwood Door & Center Console Trimmings. Apple Play & Android Auto Ready. Bluetooth, Navigation App-Waze, Backup Camera. Factory Al...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA3NC254429
Stock: NC254429A
Certified Pre-Owned: No
Listed since: 02-13-2025 - $45,995fair price$3 above market
- 27,633 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Nodine Motor Company (203 mi away)
Close
Located in Inman, SC / 203 miles away from Myrtle Beach, SC
CALL (864) 472-2021 or Toll Free 888-312-9875/ WWW.NODINEMOTORCOMPANY.COM ***Carfax History Report Available *** Print This Ad for a Special Deal --
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC256680
Stock: 256680
Certified Pre-Owned: No - Price Drop$41,516fair price$1,528 below market
- 22,232 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Ramsey, NJ / 576 miles away from Myrtle Beach, SC
CarFax No Accidents Reported,CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC364463
Stock: L17523T
Certified Pre-Owned: No - $44,495fair price$36 above market
- 28,692 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Sports & Imports (196 mi away)
Close
Located in Spartanburg, SC / 196 miles away from Myrtle Beach, SC
Introducing the all-new 2022 Lexus RX 350 F SPORT, the ultimate luxury SUV that combines performance, style, and comfort. This stunning vehicle is des...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2SZMAAXNC230571
Stock: NC230571
Certified Pre-Owned: No
Listed since: 11-23-2024 - $50,967fair price$1,530 above market
- 41,516 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Hendrick Lexus Northlake (160 mi away)
Close
Located in Charlotte, NC / 160 miles away from Myrtle Beach, SC
Nav System, Heated/Cooled Seats, Cross-Traffic Alert, CD Player, Remote Engine Start, Power Liftgate, Satellite Radio, Lane Keeping Assist PURCHASE WI...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA3NC339959
Stock: PN4743
Certified Pre-Owned: Yes
Listed since: 03-19-2025 - Price Drop$44,888fair price$1,043 below market
- 25,551 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Hennessy Lexus of Gwinnett (298 mi away)
Close
Located in Duluth, GA / 298 miles away from Myrtle Beach, SC
Hennessy Lexus of Gwinnett is proud to offer you this Exceptional 2022 Lexus RX! It comes well appointed, is exceptionally clean, and has undergone a ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC241821
Stock: G3840P
Certified Pre-Owned: Yes
Listed since: 04-20-2025 - New Listing$44,966good price$1,775 below market
- 11,229 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mt. Juliet Chrysler Dodge Jeep Ram (463 mi away)
Close
Located in Mt Juliet, TN / 463 miles away from Myrtle Beach, SC
Unveiling a truly exceptional driving experience, we proudly present the 2022 Lexus RX 350 AWD, a luxury SUV that effortlessly blends sophisticated de...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC352961
Stock: RDW1870
Certified Pre-Owned: No
Listed since: 02-08-2025 - $25,990good price$1,305 below market
- 85,342 miles
- 2 accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Georgia Auto World (320 mi away)
Close
Located in Marietta, GA / 320 miles away from Myrtle Beach, SC
***NEW ARRIVAL***LOW MILES***GOOD TIRES***GOOD BRAKES***EXCELLENT CONDITION***PARKING SENSORS**POWER LEATHER SEATS***STEERING WHEEL MOUNTED CONTROLS**...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2ZZMCA1JC109434
Stock: 109434
Certified Pre-Owned: No - Price Drop$41,300good price$1,635 below market
- 28,804 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Safford Alfa Romeo of Tysons Corner (376 mi away)
Close
Located in Vienna, VA / 376 miles away from Myrtle Beach, SC
CARFAX One-Owner. Mica 2022 Lexus RX 350 VERY WELL MAINTAINED, AWD, Glazed Caramel Artificial Leather, 3.33 Axle Ratio, 4-Wheel Disc Brakes, Alloy whe...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC325478
Stock: P2963
Certified Pre-Owned: No
Listed since: 04-09-2025 - $41,594fair price$810 below market
- 50,969 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Performance Lexus (490 mi away)
Close
Located in Cincinnati, OH / 490 miles away from Myrtle Beach, SC
Lexus L/Certified and loaded with convenient features like: Navigation, Lane-Departure Warning, Apple CarPlay, Remote Start, Cross-Traffic Alert, Back...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2JZMAA3NC248437
Stock: NC248437
Certified Pre-Owned: Yes
Listed since: 07-01-2025 - New Listing$40,449good price$2,038 below market
- 39,309 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Mercedes-Benz of Cincinnati (488 mi away)
Close
Located in Cincinnati, OH / 488 miles away from Myrtle Beach, SC
CARFAX One-Owner. Black 2022 Lexus RX 350 F Sport 3.5L V6 DOHC 24V AWD RX 350 F Sport, 4D Sport Utility, 3.5L V6 DOHC 24V, 8-Speed Automatic, AWD, Bla...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC358311
Stock: ANC358311
Certified Pre-Owned: No
Listed since: 04-08-2025 - New Listing$40,472fair price$576 below market
- 47,792 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Chrysler Dodge Jeep Ram of Culpeper (336 mi away)
Close
Located in Culpeper, VA / 336 miles away from Myrtle Beach, SC
2022 Lexus RX 350 AWDKey Features:CARFAX One-Owner.As a family-owned and operated company for over 25 years, our priority is to offer customers a bett...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDA8NC355897
Stock: 24849A
Certified Pre-Owned: No
Listed since: 07-04-2025 - $43,922fair price$964 above market
- 33,627 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Land Rover Raleigh (156 mi away)
Close
Located in Raleigh, NC / 156 miles away from Myrtle Beach, SC
Clean CARFAX. CARFAX One-Owner. Caviar 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V 1-OWNER, CLEAN CARFAX, LOCAL TRADE IN, BACK UP CAMERA,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC354794
Stock: NP70351
Certified Pre-Owned: No
Listed since: 06-08-2025 - $42,749fair price$419 below market
- 50,612 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Performance Lexus Northern Kentucky (486 mi away)
Close
Located in Fort Wright, KY / 486 miles away from Myrtle Beach, SC
This 2022 Lexus Rx 350 is loaded with convenient features like: AWD, Backup Cam, Apple CarPlay, Heated Seats, Cooled Seats, Remote Start, Nuluxe Trim,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC362907
Stock: NC362907A
Certified Pre-Owned: No
Listed since: 06-28-2025 - $25,999fair price$227 above market
- 51,313 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Lakeland Toyota (425 mi away)
Close
Located in Lakeland, FL / 425 miles away from Myrtle Beach, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2ZZMCAXJC097297
Stock: JC097297
Certified Pre-Owned: No
Listed since: 05-08-2025 - $44,250fair price$902 below market
- 35,657 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Toyota of Cool Springs (474 mi away)
Close
Located in Franklin, TN / 474 miles away from Myrtle Beach, SC
SummaryEnjoy Peace of Mind with every purchase at Toyota of Cool Springs with our 3-Day, NO QUESTIONS ASKED Exchange Option. If you change yo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA2NC223186
Stock: W555422A
Certified Pre-Owned: No
Listed since: 06-24-2025
Showing 1,114 - 1,134 out of 3,001 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Avid RX owner
Wendy, 12/08/2019
2020 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A)
I drive extensively and this is my fifth RX. Yes number 5, when you drive to remote areas it all about realizability. Previously I had the 2015 RX which drove fine but had slot of temperamental electronics. The new 2020 has premium package offers every safety feature, brake hold, cross traffic front and rear, blind spot warning you name it. I do love the heated steering wheel, and the … auto heated seats. The app works great for remote start and locking. My only comment is I think the car sounds a bit tinny when you run it through the car was and at times when closing the doors, I hope the body is still as rugged as my previous models. Highly recommend.
Used 2022 Lexus RX 350 in Myrtle Beach, SC Values
Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,525 | $35,333 | $37,218 |
| Clean | $33,078 | $34,844 | $36,683 |
| Average | $32,334 | $34,028 | $35,791 |
| Rough | $31,366 | $32,967 | $34,632 |
The average list price of a used 2022 Lexus RX 350 in Myrtle Beach, South Carolina is $42,248. The average mileage on a used Lexus RX 350 2022 for sale in Myrtle Beach, South Carolina is 35,571. Based on the average mileage of 35,571 for used 2022 Lexus RX 350 for sale in Myrtle Beach, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Myrtle Beach, South Carolina to be $32,334.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.