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1,789 listings
  • Price Drop
    • 99,057 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Tom Kelley Chevrolet of Decatur (453 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Decatur, IN / 453 miles away from Des Moines, IA

    CARFAX One-Owner. 2021 Lexus RX 350 RX 350, 3.5L V6 DOHC 24V, AWD. 3.5L V6 DOHC 24V Obsidian 19/26 City/Highway MPGWhere else can you shop 7 brands ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTJHZMDA4M2051141
    Stock: 13B13081
    Certified Pre-Owned: No
    Listed since: 04-28-2025

  • Stock photo**
    $33,787
    fair price
    $472 below market
    • 67,609 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Peoria (214 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Peoria, IL / 214 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA2KC190303
    Stock: PL2343A
    Certified Pre-Owned: Yes
    Listed since: 05-31-2025

  • New Listing
    $38,999
    fair price
    $958 below market
    • 48,928 miles
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Wayzata (233 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Wayzata, MN / 233 miles away from Des Moines, IA

    Recent Arrival! CARFAX One-Owner. Certified. Nightfall Mica 2021 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V AWD 19/26 City/Highway MPG Clean CARFA...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA5MC279942
    Stock: L241500A
    Certified Pre-Owned: Yes
    Listed since: 06-12-2025

  • Price Drop
    $28,112
    fair price
    $103 above market
    • 62,216 miles
    • 1 accident, 3 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Zeigler Cadillac of Lincolnwood (303 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lincolnwood, IL / 303 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA8HC112908
    Stock: P4475
    Certified Pre-Owned: No
    Listed since: 05-15-2025

  • New Listing
    • 10,899 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 633 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA7KC119855
    Stock: 2003797141
    Certified Pre-Owned: No
    Listed since: 06-07-2025

  • Price Drop
    $23,222
    good price
    $1,713 below market
    • 104,719 miles
    • 2 accidents, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Mission Hills, CA / 1,440 miles away from Des Moines, IA

    High Demand,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Keyless Start,Lane Keeping Assist,Satellite Radi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA2KC146655
    Stock: KC146655T
    Certified Pre-Owned: No

  • Stock photo**
    $33,900
    fair price
    $494 above market
    • 55,283 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Spirit Lexus (263 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in St. Louis, MO / 263 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA4KC196233
    Stock: P5N196233
    Certified Pre-Owned: Yes
    Listed since: 05-31-2025

  • Price Drop
    $31,600
    fair price
    $237 below market
    • 83,637 miles
    • 1 accident, 2 owners, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • Crain Kia of Bentonville (365 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Bentonville, AR / 365 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA2KC210968
    Stock: AL8673
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • $29,900
    fair price
    $671 above market
    • 78,358 miles
    • 2 accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Acura of Springfield (308 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Springfield, MO / 308 miles away from Des Moines, IA

    2019 Lexus RX 350 CARFAX One-Owner. AWD Locally Owned!, 3500 lbs Tow Prep Package, Cold Area Package, Driver Seat Memory w/3 Settings, Engine Cooler, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA4KC190190
    Stock: 53278A
    Certified Pre-Owned: No
    Listed since: 04-21-2025

  • New Listing
    $31,998
    fair price
    $869 above market
    • 40,769 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from WA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Puyallup, WA / 1,459 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA8KC177636
    Stock: 27195149
    Certified Pre-Owned: No

  • $30,998
    good price
    $1,632 below market
    • 43,618 miles
    • 2 accidents, 2 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Victorville, CA / 1,375 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA2KC125174
    Stock: 27383036
    Certified Pre-Owned: No

  • Price Drop
    • 18,942 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from WA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Renton, WA / 1,457 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCAXKC187018
    Stock: 27194577
    Certified Pre-Owned: No

    • 79,561 miles
    • No accidents, 2 owners, rental vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • McCarthy Chevrolet (198 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Olathe, KS / 198 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCAXKC175807
    Stock: UC57952B
    Certified Pre-Owned: No
    Listed since: 05-13-2025

  • New Listing
    • 51,862 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Bergstrom Chevrolet of Appleton (319 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Appleton, WI / 319 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA2HC056044
    Stock: I5062
    Certified Pre-Owned: No
    Listed since: 05-29-2025

  • New Listing
    • 81,640 miles
    • No accidents, 3 owners, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax Joliet (279 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Plainfield, IL / 279 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA0HC070346
    Stock: 27266956
    Certified Pre-Owned: No

    • 29,883 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Memphis (495 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Memphis, TN / 495 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA6KC138719
    Stock: P5250
    Certified Pre-Owned: No
    Listed since: 06-04-2025

  • Price Drop
    • 41,384 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Phoenix, AZ / 1,151 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA4KC140811
    Stock: 2003734982
    Certified Pre-Owned: No
    Listed since: 05-10-2025

    • 68,206 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Merrillville (321 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Merrillville, IN / 321 miles away from Des Moines, IA

    BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, ONE OWNER!, LOW MILEAGE!, Eminent White Pearl 2021 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2AZMDA5MC276251
    Stock: PM2734
    Certified Pre-Owned: No
    Listed since: 05-12-2025

    • 95,324 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Triumph Auto Sales (487 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Memphis, TN / 487 miles away from Des Moines, IA

    View all of our inventory at TRIUMPHAUTOSALES.COM. Call for more details at 901-380-5464 or come by 4875 Elmore Rd. All cars are pre-owned and sold...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA9HC045203
    Stock: 6110
    Certified Pre-Owned: No

    • 61,670 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax Schaumburg (286 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Schaumburg, IL / 286 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA7HC057626
    Stock: 27346494
    Certified Pre-Owned: No

    • 65,037 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Carvana - Chicago (271 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Chicago, IL / 271 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA1HC134782
    Stock: 2003718131
    Certified Pre-Owned: No
    Listed since: 06-06-2025

Showing 148 - 168 out of 1,789 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
3.9 out of 5 stars59 Reviews
Write a vehicle reviewSee all 59 reviews
  • 5 star
    (51%)
  • 4 star
    (14%)
  • 3 star
    (17%)
  • 2 star
    (12%)
  • 1 star
    (7%)
4 out of 5 stars

great car horrible navigation system and traffic

stan nelson, 01/12/2019
2019 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A)
leased new awd rx350 and went on 2k mile trip to colorado. the car is great, quite and very comfy. the navigation is a joke. traffic shows green at all times even if your in super bumper to bumper traffic. the green lines are so big that it overwhelms the map and has all the surface streets painted green as well. its hard to tell where the highway is when your in a city area. the arrow … that indicates where the car is will drift off the road your on and float out into the non-street area. panning the map to show a different view is next to impossible. this being my first lexus shocked me how bad this is. my 8 year old acura nav is light years ahead of this. i wont lease another if there is not major improvments made.
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Used 2021 Lexus RX 350 in Des Moines, IA Values

Estimated values
2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$26,508$28,681$30,859
Clean$26,093$28,226$30,361
Average$25,403$27,467$29,531
Rough$24,506$26,480$28,452

The average list price of a used 2021 Lexus RX 350 in Des Moines, Iowa is $32,354. The average mileage on a used Lexus RX 350 2021 for sale in Des Moines, Iowa is 61,362. Based on the average mileage of 61,362 for used 2021 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2021 in Des Moines, Iowa to be $25,403.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.