2010 Toyota Sienna Limited 7-Passenger 4dr Minivan (3.5L 6cyl 5A)
Chose Sienna (smoother, quieter ride) over Odyssey (sportier ride and seemed less quiet on freeways). Pregnant wife got car sick once during late night travel, and the GPS conveniently tracked the nearest hotel for us. Really like the interior spaciousness, although the Sienna was a tight fit in the 3rd car garage... the dual sliding doors made for easier ingress/egress since there were large shelves along the walls of the garage. Our Sienna has every option including HID lights, DVD Rear Entertainment, and JBL (above average audio... although nothing beats Mark Levinson). Dynamic laser cruise control is probably the only option not worth buying.
Bluetooth connectivity is excellent convenience for hands-free cell phone usage. Dual power sliding doors is great especially if you have children. GPS navigation helpful in heavy traffic if you need to make a detour. Interior spaciousness makes long distance travels a bit less tiring.
Next generation should have even better gas mileage, more power.