Skip to main content
Skip to Filters
221 listings
  • $75,995
    great price
    $8,944 below market
    • 8,689 miles
    • No accidents, 1 owner, personal use only
    • 8'2” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49PEY3RF252334
    Stock: L254977A
    Certified Pre-Owned: Yes
    Listed since: 06-30-2025

  • $53,995
    great price
    $5,605 below market
    • 92,872 miles
    • No accidents, 2 owners, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    Recent Trade! Denali 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. Navigation System, Power Sunroof, Towing Package, Heavy Duty Trailering Package, 3.42 R...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY3NF271343
    Stock: L254635A
    Certified Pre-Owned: No
    Listed since: 06-18-2025

  • Price Drop
    $73,000
    great price
    $8,010 below market
    • 12,026 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • South County Dodge Chrysler Jeep Ram (91 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Saint Louis, MO / 91 miles away from Cape Girardeau, MO

    Volcanic Red Tintcoat 2024 GMC Sierra 2500HD AT4 4WD 10-Speed Automatic Duramax 6.6L V8 Turbodiesel 1 OWNER, ACCIDENT FREE AUTOCHECK, BACK UP CAMERA, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    Listing Information:

    VIN: 1GT49PEY0RF431205
    Stock: S0823AA
    Certified Pre-Owned: No
    Listed since: 06-13-2025

  • Price Drop
    • 20,709 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49XEY6RF119325
    Stock: L254148A
    Certified Pre-Owned: Yes
    Listed since: 05-07-2025

    • 11,288 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49XEY8RF381699
    Stock: L254801A
    Certified Pre-Owned: Yes
    Listed since: 07-14-2025

  • Price Drop
    $52,952
    great price
    $8,042 below market
    • 52,663 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • AutoCenters Nissan (78 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Herculaneum, MO / 78 miles away from Cape Girardeau, MO

    ONE OWNER with ZERO ACCIDENTS, Four Wheel Drive, X31 Off-Road Package, Heated and Ventilated Leather Front Bucket Seats, Remote Start, Apple CarPlay/A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT19PE72NF303729
    Stock: HK84438
    Certified Pre-Owned: No
    Listed since: 05-19-2025

  • Price Drop
    $72,995
    good price
    $4,311 below market
    • 19,177 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY7RF324020
    Stock: L255096A
    Certified Pre-Owned: Yes
    Listed since: 06-24-2025

  • $50,995
    great price
    $5,171 below market
    • 92,454 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    1-Owner New Vehicle Trade! Denali 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. Navigation System, Power Sunroof, Towing Package, Heavy Duty Trailering Pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY7LF153910
    Stock: L253860A
    Certified Pre-Owned: No
    Listed since: 04-19-2025

  • Stock photo**
    $31,950
    great price
    $6,026 below market
    • 98,404 miles
    • No accidents, 3 owners, personal use only
    • 6'7” bed, 6l, 8cyl
    • Baldwin Toyota (58 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Poplar Bluff, MO / 58 miles away from Cape Girardeau, MO

    EquipmentSee what's behind you with the back up camera on the GMC Sierra. The leather seats in this unit are a must for buyers looking for com...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT12TEG0JF199054
    Stock: 26800A2
    Certified Pre-Owned: No
    Listed since: 03-20-2025

  • Price Drop
    $58,495
    great price
    $4,831 below market
    • 59,978 miles
    • 1 accident, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY9MF146121
    Stock: L254633A
    Certified Pre-Owned: Yes
    Listed since: 06-04-2025

  • $84,175
    good price
    $3,952 below market
    • 8,325 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • AutoCenters Nissan (78 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Herculaneum, MO / 78 miles away from Cape Girardeau, MO

    ZERO ACCIDENTS, Turbodiesel, Four Wheel Drive, Sunroof, Heated and Ventilated Massaging Leather Front Bucket Seats, Adaptive Cruise, Remote Start, Bli...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT4UZEY4SF136883
    Stock: RK83998
    Certified Pre-Owned: No
    Listed since: 04-08-2025

  • $74,736
    good price
    $4,673 below market
    • 27,471 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Sapaugh GM Country (77 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Herculaneum, MO / 77 miles away from Cape Girardeau, MO

    ** We are 15 minutes south of St. Louis. Everyone leaves happy! Sterling Metallic 2024 GMC Sierra 2500HD AT4 4WD 10-Speed Automatic Duramax 6.6L V8 Tu...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49PEY8RF148373
    Stock: 2533151
    Certified Pre-Owned: No
    Listed since: 06-11-2025

  • Price Drop
    $56,995
    good price
    $4,472 below market
    • 75,064 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    1-Owner New Vehicle Trade, Sold Here New! Denali 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. Power Sunroof, Towing Package, Heavy Duty Trailering Packag...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY1NF354396
    Stock: L255797A
    Certified Pre-Owned: No
    Listed since: 07-01-2025

  • New Listing
    $32,995
    great price
    $2,864 below market
    • 206,203 miles
    • 6'7” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    1-Owner New Vehicle Trade! Denali 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. Z71, Navigation System, Power Sunroof, Towing Package, Heavy Duty Traileri...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    Listing Information:

    VIN: 1GT12SEY3KF140973
    Stock: L254729A
    Certified Pre-Owned: No
    Listed since: 07-21-2025

  • New Listing
    $81,995
    good price
    $3,219 below market
    • 31,150 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    1-Owner New Vehicle Trade! AT4X 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. AEV Edition, Navigation System, Power Sunroof, Towing Package, Heavy Duty Tr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49ZEY2RF406317
    Stock: L254631A
    Certified Pre-Owned: No
    Listed since: 07-19-2025

  • New Listing
    $69,995
    fair price
    $1,356 below market
    • 4,083 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    1-Owner New Vehicle Trade! Denali 6.6 V8 Duramax Turbo Diesel Crew Cab 4x4. Navigation System, Power Sunroof, Towing Package, Heavy Duty Trailering Pa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REY7LF247057
    Stock: L255354A
    Certified Pre-Owned: Yes
    Listed since: 07-07-2025

  • $39,995
    great price
    $1,386 below market
    • 29,933 miles
    • 1 accident, 1 owner, personal use only
    • 8'2” bed, 6.6l, 8cyl
    • AutoCenters Nissan (78 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Upgraded Headlights
    • Tire Pressure Warnin...
    Close

    Located in Herculaneum, MO / 78 miles away from Cape Girardeau, MO

    ONE OWNER VEHICLE, Four Wheel Drive, 2D Standard Cab, 4WD, Summit White, 2-Speaker Audio System Feature, 2-Speed Electronic Shift Transfer Case, 3.73 ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT39LE75PF218260
    Stock: R84475
    Certified Pre-Owned: No
    Listed since: 05-21-2025

  • $57,995
    fair price
    $2,338 below market
    • 65,890 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • Laura Buick GMC (98 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Collinsville, IL / 98 miles away from Cape Girardeau, MO

    This Certified Pre-Owned vehicle comes with the following benefits: -12-month/12,000-mile Bumper-to-Bumper Limited Warranty (whichever comes first) fr...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49PEY6LF232439
    Stock: L254584A
    Certified Pre-Owned: Yes
    Listed since: 07-11-2025

  • Price Drop
    $39,500
    good price
    $3,153 below market
    • 102,155 miles
    • 2 accidents, 4 owners, personal use only
    • 6'7” bed, 6.6l, 8cyl
    • Victory Toyota of St. Louis (93 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Saint Louis, MO / 93 miles away from Cape Girardeau, MO

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT12UE82GF141745
    Stock: P12798
    Certified Pre-Owned: No
    Listed since: 09-12-2024

  • $74,885
    fair price
    $1,600 above market
    • 7,390 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • AutoCenters Nissan (78 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Herculaneum, MO / 78 miles away from Cape Girardeau, MO

    ONE OWNER with ZERO ACCIDENTS, Turbodiesel, Four Wheel Drive, Technology Package, Gooseneck/5th Wheel Prep Package, X31 Off-Road Package, Trailering P...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT49REYXRF251726
    Stock: T84371
    Certified Pre-Owned: No
    Listed since: 05-09-2025

  • $70,580
    fair price
    $814 above market
    • 22,454 miles
    • No accidents, 1 owner, personal use only
    • 6'10” bed, 6.6l, 8cyl
    • AutoCenters Nissan (78 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Herculaneum, MO / 78 miles away from Cape Girardeau, MO

    ONE OWNER with ZERO ACCIDENTS, Turbodiesel, Four Wheel Drive, AT4 Premium Plus Package, AT4 Preferred Package, Technology Package, X31 Off-Road Packag...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    Listing Information:

    VIN: 1GT19PEY2RF238752
    Stock: RK84003
    Certified Pre-Owned: No
    Listed since: 04-08-2025

Showing 1 - 21 out of 221 listings

Buying a GMC Sierra 2500HD in Cape Girardeau Missouri

For those navigating the diverse terrain of Cape Girardeau, MO, the GMC Sierra 2500HD stands as a robust option, thanks to its powerful engine options and impressive hauling capabilities. Whether you're heading towards the Mississippi River for outdoor activities or commuting through the rolling hills and rural roads, this heavy-duty pickup excels in providing the strength needed to manage various tasks. Its variety of configurations, including an off-road-focused model, also means you can tailor it to your specific needs, whether you're an avid outdoorsman or looking for a reliable workhorse.

Filters
Skip to Results

Applied Filters4Active

Select Buying Experience

Location

Search radius100 miles
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Trim

Truck Details

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

Listing Details