Skip to main content
Skip to Filters
631 listings
  • $50,981
    great price
    $9,973 below market
    • 63,288 miles
    • 6'10” bed, 6.6l, 8cyl
    • 86 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 86 miles away from Ocala, FL

    Summit White 2021 GMC Sierra 2500HD AT4 Duramax 6.6L V8 Turbodiesel 4WD 10-Speed Automatic Leather Seats, Sunroof/Moonroof, Heated/Cooled Seats, Backu...

    Listing Information:
    VIN:
    1GT49PEY3MF242220
    Stock:
    T6559A
    Certified Pre-Owned:
    No
    Listed since:
    10-16-2026
  • $60,570
    good price
    $3,696 below market
    • 19,342 miles
    • 6'10” bed, 6.6l, 8cyl
    • 86 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Tampa, FL / 86 miles away from Ocala, FL

    CARFAX One-Owner. Recent Arrival! Cayenne Red 2021 GMC Sierra 2500HD Denali Duramax 6.6L V8 Turbodiesel 4WD 10-Speed Automatic Leather Seats, Sunroof/...

    Listing Information:
    VIN:
    1GT49REY5MF131406
    Stock:
    T3917AA
    Certified Pre-Owned:
    No
    Listed since:
    10-27-2026
  • $53,999
    fair price
    $5,189 below market
    • 70,453 miles
    • 6'10” bed, 6.6l, 8cyl
    • 83 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 83 miles away from Ocala, FL

    NO DEALER FEES. NO GAMES. NO SURPRISES. JUST REAL PRICING. AT VETERANS FORD, ONLY TAX AND REGISTRATION REMAIN.This 2021 GMC Sierra 2500HD AT4 Premium ...

    Listing Information:
    VIN:
    1GT49PEY9MF222473
    Stock:
    MF222473
    Certified Pre-Owned:
    No
    Listed since:
    10-28-2026
  • Price Drop
    $60,232
    fair price
    $974 below market
    • 37,658 miles
    • 6'10” bed, 6.6l, 8cyl
    • 49 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Brooksville, FL / 49 miles away from Ocala, FL

    At Buick GMC Brooksville, we believe buying a vehicle should be a straightforward, stress-free experience built on honesty and transparency. That's wh...

    Listing Information:
    VIN:
    1GT49REY9MF216409
    Stock:
    MF216409
    Certified Pre-Owned:
    Yes
    Listed since:
    07-04-2026
  • $52,650
    fair price
    $3,431 below market
    • 90,993 miles
    • 6'10” bed, 6.6l, 8cyl
    • 77 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Holiday, FL / 77 miles away from Ocala, FL

    HEAVY DUTY CAPABILITY. AT4 OFF ROAD STYLE. GMC POWER! The 2021 GMC Sierra 2500HD AT4 combines heavy duty truck capability, rugged off road inspired st...

    Listing Information:
    VIN:
    1GT49PEY7MF195502
    Stock:
    X138039C
    Certified Pre-Owned:
    No
    Listed since:
    10-31-2026
  • Price Drop
    $53,586
    fair price
    $1,273 below market
    • 81,283 miles
    • 6'10” bed, 6.6l, 8cyl
    • 86 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Jacksonville, FL / 86 miles away from Ocala, FL

    This 2021 GMC Sierra 2500HD Denali combines capability with refinement. The Duramax 6.6L turbodiesel engine and 4WD system handle demanding tasks whil...

    Listing Information:
    VIN:
    1GT49REY0MF167455
    Stock:
    CFJTMF167455
    Certified Pre-Owned:
    No
    Listed since:
    08-26-2026
    • 67,336 miles
    • 6'10” bed, 6.6l, 8cyl
    • 4 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Ocala, FL / 4 miles away from Ocala, FL

    This 2021 GMC Sierra 2500HD Denali delivers premium capability and refined comfort in a powerful diesel package. With the legendary Duramax 6.6L V8 Tu...

    Listing Information:
    VIN:
    1GT49REY2MF144131
    Stock:
    26M744A
    Certified Pre-Owned:
    No
    Listed since:
    10-19-2026
  • Price Drop
    $46,389
    good price
    $7,519 below market
    • 97,837 miles
    • 6'10” bed, 6.6l, 8cyl
    • 81 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 81 miles away from Ocala, FL

    Listing Information:
    VIN:
    1GT49PEY5MF195935
    Stock:
    17973
    Certified Pre-Owned:
    No
  • $46,110
    great price
    $5,162 below market
    • 109,646 miles
    • 6'10” bed, 6.6l, 8cyl
    • 4 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Ocala, FL / 4 miles away from Ocala, FL

    This 2020 GMC Sierra 2500HD Denali delivers the capability and refinement you expect from a premium heavy-duty truck built to handle demanding work an...

    Listing Information:
    VIN:
    1GT49REY8LF154127
    Stock:
    26K597A
    Certified Pre-Owned:
    No
    Listed since:
    07-28-2026
  • Price Drop
    • 56,726 miles
    • 8'2” bed, 6.6l, 8cyl
    • 90 mi away
    • Back-up camera
    • Bluetooth
    • Upgraded Headlights
    • Tire Pressure Warnin...
    • USB Inputs
    Close

    Located in Titusville, FL / 90 miles away from Ocala, FL

    This 2021 GMC Sierra 2500HD Base delivers serious capability with its powerful 6.6L V8 engine paired with a 6-speed automatic transmission. Built for ...

    Listing Information:
    VIN:
    1GT08LE74MF171773
    Stock:
    171773T
    Certified Pre-Owned:
    Yes
    Listed since:
    08-25-2026
  • $51,000
    great price
    $10,259 below market
    • 84,116 miles
    • 6'10” bed, 6.6l, 8cyl
    • 67 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Saint Augustine, FL / 67 miles away from Ocala, FL

    This 2022 GMC Sierra 2500HD AT4 commands the road with serious capability. Built on a 6.6L V8 Diesel Turbocharged engine paired with a 10-Speed Automa...

    Listing Information:
    VIN:
    1GT49PEY0NF317537
    Stock:
    NF317537
    Certified Pre-Owned:
    No
    Listed since:
    10-05-2026
  • Price Drop
    $49,480
    • 89,483 miles
    • 6'10” bed, 6.6l, 8cyl
    • 81 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 81 miles away from Ocala, FL

    *Call today to schedule your test drive! (813) 443-8244. Se habla espanol! *Personal checks not accepted. Cashier's checks only and must be verified b...

    Listing Information:
    VIN:
    1GT49PE75MF293564
    Stock:
    293564
    Certified Pre-Owned:
    No
    Listed since:
    10-14-2026
  • Price Drop
    $54,047
    good price
    $3,715 below market
    • 73,107 miles
    • 6'10” bed, 6.6l, 8cyl
    • 52 mi away
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Deland, FL / 52 miles away from Ocala, FL

    Elevate your driving experience with this exceptional 2022 GMC Sierra 2500HD Denali. Meticulously crafted to deliver uncompromising power, advanced te...

    Listing Information:
    VIN:
    1GT49REY6NF147647
    Stock:
    36154AT
    Certified Pre-Owned:
    No
    Listed since:
    04-18-2026
  • $57,778
    good price
    $2,086 below market
    • 44,192 miles
    • 6'10” bed, 6.6l, 8cyl
    • 34 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Crystal River, FL / 34 miles away from Ocala, FL

    BACK UP CAMERA, NAVIGATION SYSTEM, LEATHER SEATS, BLUETOOTH, HEAT PACKAGE, MEMORY PACKAGE, REMOTE START, TOW PACKAGE, 10-Speed Automatic, 4WD, Dark Wa...

    Listing Information:
    VIN:
    1GT49REY7LF129526
    Stock:
    F3181A
    Certified Pre-Owned:
    No
    Listed since:
    10-21-2026
  • $50,983
    fair price
    $1,824 below market
    • 56,092 miles
    • 6'10” bed, 6.6l, 8cyl
    • 123 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Bradenton, FL / 123 miles away from Ocala, FL

    Engine; Duramax 6.6L Turbo-Diesel V8; B20-Diesel CompatibleAt4 Premium PackageTechnology PackageAt4 Preferred PackageWheels; 20" (50.8 Cm) 6-Spoke...

    Listing Information:
    VIN:
    1GT49PEY2LF271738
    Stock:
    LF271738
    Certified Pre-Owned:
    No
    Listed since:
    11-01-2026
  • Price Drop
    $56,998
    fair price
    $1,510 above market
    • 45,956 miles
    • 6'10” bed, 6.6l, 8cyl
    • 78 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Tampa, FL / 78 miles away from Ocala, FL

    Wanna drive? CarMax puts you in the driver's seat-and that includes transparency and pricing without document or processing fees. Certain cars may hav...

    Listing Information:
    VIN:
    1GT49REY9NF267992
    Stock:
    28754370
    Certified Pre-Owned:
    No
  • $53,000
    fair price
    $921 below market
    • 80,179 miles
    • 6'10” bed, 6.6l, 8cyl
    • 184 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Fort Myers, FL / 184 miles away from Ocala, FL

    Recent Arrival!NO DEALER FEE, BLUETOOTH/ HANDS FREE CELL PHONE, APPLE CAR PLAY, LEATHER, REAR BACK UP CAMERA, KEYLESS START.Certified. CarBravo Ce...

    Listing Information:
    VIN:
    1GT49REY7NF131585
    Stock:
    U24324
    Certified Pre-Owned:
    Yes
    Listed since:
    10-30-2026
  • $60,969
    great price
    $7,915 below market
    • 30,036 miles
    • 6'10” bed, 6.6l, 8cyl
    • 175 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Cape Coral, FL / 175 miles away from Ocala, FL

    10-Speed Automatic, 4WD, Jet Black Leather, 12-Volt Rear Auxiliary Power Outlet, 120-Volt Bed Mounted Power Outlet, 120-Volt Instrument Panel Power Ou...

    Listing Information:
    VIN:
    1GT49REY4PF239830
    Stock:
    A239830
    Certified Pre-Owned:
    No
    Listed since:
    09-21-2026
  • $53,987
    fair price
    $661 below market
    • 81,888 miles
    • 6'10” bed, 6.6l, 8cyl
    • 67 mi away
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Orlando, FL / 67 miles away from Ocala, FL

    Listing Information:
    VIN:
    1GT49REY4NF156511
    Stock:
    F156511
    Certified Pre-Owned:
    No
  • $48,581
    good price
    $5,342 below market
    • 73,703 miles
    • 6'10” bed, 6.6l, 8cyl
    • 80 mi away
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Tampa, FL / 80 miles away from Ocala, FL

    CarFax No Accidents Reported, CarFax 1-Owner, Rare Find,Apple CarPlay,Back-Up Camera,Bluetooth,Heated Seats,Heated Seats,Heated Seats,Heated Steering ...

    Listing Information:
    VIN:
    1GT49PEY5PF126408
    Stock:
    PF126408R
    Certified Pre-Owned:
    No
  • $55,990
    fair price
    • 42,424 miles
    • 6'10” bed, 6.6l, 8cyl
    • In-stock online
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 901 miles away from Ocala, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    Listing Information:
    VIN:
    1GT49PEY3MF234604
    Stock:
    3006874667
    Certified Pre-Owned:
    No
    Listed since:
    10-30-2026
Showing 1 - 21 out of 631 listings

Consumer Reviews for the GMC Sierra 2500HD

Read recent reviews for the GMC Sierra 2500HD
Overall Consumer Rating
4.3 out of 5 stars27 Reviews
Write a vehicle reviewSee all 27 reviews
  • 5 star
    (70%)
  • 4 star
    (7%)
  • 3 star
    (7%)
  • 2 star
    (11%)
  • 1 star
    (4%)
4 out of 5 stars

Love the looks, love the power, love the economy

Rick B., 03/18/2021
2020 GMC Sierra 2500HD AT4 4dr Crew Cab 4WD SB (6.6L 8cyl 6A)
I purchased a 2020 Sierra 2500HD AT4 (Duramax) in November of 2020. This thing is a BEAST and a joy to drive. I've put almost 131K miles on it thus far and have not had a single issue. IMHO, the interior is better than a Ford but trails behind the Dodge. However, just because it seems less capable with technology isn't necessarily true. I have physical switches for many things that … the Dodge incorporates in their big screen. I MUCH prefer the switches because I don't have to go through electronic pages to find what I'm looking for. The seats are a bit hard but are very supportive. I'm averaging a 21mpg with it at this point but the majority (80%) of my driving is highway speeds. In an attempt see just how good of gas mileage I could get, I drove a cruise controlled speed of 55 mph on a VERY flat 2 lane road for a little over 75 miles. My results, 29.3mpg, yep, you read that right. As I get up to interstate cruising speed it's much closer to 22mpg. I have hauled my 6,000 pound boat a couple of times with it and it still gets around 14mpg. Speaking of hauling the boat, this thing tows like a dream. The cameras, mirrors and tow-haul mode work great and if I couldn't see the boat in my mirrors, I would hardly know it's there. The voice command menu and responsiveness is great, no issues with it and it has always recognized what I'm asking for. The Bose speakers produce more than I can listen to, and the cab is quiet enough for conference calls when I'm travelling for work. The in-cab outlet is perfect for charging my laptop on the go and allows my wife to use the computer when we travel without killing the battery. I put a hardcover on the bed but with the multipro tailgate I rarely have to do anything with it, and I make a LOT of trips to the lumber yard for 8'+ lumber. All I have to do is drop the upper portion of the tailgate and the long lumber slides right in and is safe and secure. One thing I would criticize. It doesn't match up when compared to the other makers off-roading capabilities (manual/push button locking differentials), but I didn't really buy it for that. If you want something to do some relatively challenging off-road cruising, look elsewhere. I could go on, but suffice it to say that I LOVE this truck and would absolutely recommend it without hesitation.
Report abuse

FAQ

Can the 2021 GMC Sierra 2500HD be bought in the United States?

Yes. The 2021 GMC Sierra 2500HD is sold in the United States, with MSRPs starting around $40,300 for the base 2WD Crew Cab short bed and reaching about $65,100 for the Denali 4WD long bed.

Does the 2021 GMC Sierra 2500HD have a pickup body style?

Yes. The 2021 GMC Sierra 2500HD is a heavy-duty full-size pickup truck offered in Regular Cab, Double Cab and Crew Cab body styles.
Filters
Skip to Results

Applied Filters4Active

Select Buying Experience

Location

Search radius200 miles
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Trim

Truck Details

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

Listing Details

Seller Type


* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.