Skip to main content
Skip to Filters
329 listings
    • 23,847 miles
    • No accidents, 2 owners, personal use
    • 21 City / 31 Hwy MPG
    • Cloninger Ford (473 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Salisbury, NC / 473 miles away from Tupelo, MS

    *APPLE CAR PLAY*, *BACKUP CAMERA*, *HEATED SEATS*, *LEATHER SEATS*, *MOONROOF/SUNROOF*, *BLIND SPOT DETECTION*, *Bluetooth *, *CLEAN CARFAX*, *DEALER...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D29M5109642
    Stock: PS7682AF
    Certified Pre-Owned: No
    Listed since: 06-14-2025

  • New Listing
    $24,399
    fair price
    $503 above market
    • 78,923 miles
    • 21 City / 30 Hwy MPG
    • AutoNation Hyundai Mall of Georgia (269 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Buford, GA / 269 miles away from Tupelo, MS

    Sun/MoonroofLane Keeping AssistKeyless StartThis vehicle includes a Money-Back Guarantee* and passed our precise inspection process. Best of all ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    26 Combined MPG (21 City/30 Highway)

    Listing Information:

    VIN: JTHBA1D25K5097613
    Stock: K5097613
    Certified Pre-Owned: No
    Listed since: 07-12-2025

  • New Listing
    • 45,738 miles
    • No accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • CarMax Memphis (90 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Memphis, TN / 90 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHC81D2XK5035107
    Stock: 27104078
    Certified Pre-Owned: No

  • Price Drop
    • 39,309 miles
    • Frame damage reported, 2 owners, personal use
    • 21 City / 31 Hwy MPG
    • Carma Automotive Group (259 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Duluth, GA / 259 miles away from Tupelo, MS

    Carma Automotive Group Please Call Sales! 4189 Abbotts Bridge Rd. Duluth, GA 30*** 4**-7**-4993 **PLEASE READ CAREFULLY** WELL-MAINTAINED WITH DEALER ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D27M5111325
    Stock: 20496CO
    Certified Pre-Owned: No
    Listed since: 05-24-2025

  • New Listing
    • 31,034 miles
    • No accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Hendrick Lexus Northlake (451 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Charlotte, NC / 451 miles away from Tupelo, MS

    Moonroof, Heated Seats, Fog Lamps, Smart Device Integration, WiFi Hotspot, Lane Keeping Assist, Keyless Start, Premium Sound System PURCHASE WITH CONF...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D25P5125748
    Stock: PN4867
    Certified Pre-Owned: No
    Listed since: 07-12-2025

  • Stock photo**
    • 9,756 miles
    • No accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Motorcars Louisiana (303 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Baton Rouge, LA / 303 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D27P5126377
    Stock: 20729
    Certified Pre-Owned: No
    Listed since: 03-09-2025

    • 33,508 miles
    • No accidents, 2 owners, personal use
    • 21 City / 31 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in San Antonio, TX / 666 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHAA1D20M5110637
    Stock: 2003803400
    Certified Pre-Owned: No
    Listed since: 06-11-2025

    • 9,375 miles
    • 1 accident, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Grand Motorcars Kennesaw (236 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Kennesaw, GA / 236 miles away from Tupelo, MS

    Vehicle Overview Black Artificial Leather, Auto-Dimming Rearview Mirror w/HomeLink System, Comfort Package, Heated & Ventilated Front Seats, Heated Le...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D25P5126099
    Stock: P5126099
    Certified Pre-Owned: No
    Listed since: 04-12-2025

    • 40,262 miles
    • No accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Grand Motorcars (240 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Marietta, GA / 240 miles away from Tupelo, MS

    Priced below KBB Fair Purchase Price! Glazed Caramel Artificial Leather, Auto-Dimming Outside Mirrors with Tilt-Down Reverse, Auto-Dimming Rearview Mi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D23P5127661
    Stock: P5127661
    Certified Pre-Owned: No
    Listed since: 06-26-2025

  • Price Drop
    • 46,371 miles
    • No accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Gravity Autos Sandy Springs (248 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Atlanta, GA / 248 miles away from Tupelo, MS

    REAR VIEW BACK-UP CAMERA!, MOONROOF!, Black w/Perforated NuLuxe Seat Trim, 10 Speakers, 4-Wheel Disc Brakes, ABS brakes, Air Conditioning, Alloy wheel...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D26P5124457
    Stock: 124457
    Certified Pre-Owned: No
    Listed since: 05-22-2025

  • New Listing
    • 38,537 miles
    • No accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from MD to MS*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Laurel, MD / 736 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHC81F26M5045522
    Stock: 27653104
    Certified Pre-Owned: No

    • 41,322 miles
    • No accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Buffalo, NY / 794 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHC81F21M5047078
    Stock: 2003763573
    Certified Pre-Owned: No
    Listed since: 07-03-2025

    • 34,865 miles
    • No accidents, 2 owners, personal use
    • 21 City / 31 Hwy MPG
    • Pitts Toyota (354 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Dublin, GA / 354 miles away from Tupelo, MS

    Silver 2021 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged Black Artificial Leather, Accessory Package, Cargo Net, Carpet Trunk Mat, Key Glov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHAA1D28M5116363
    Stock: 97379
    Certified Pre-Owned: No
    Listed since: 04-24-2025

  • Price Drop
    $32,998
    fair price
    $1,625 above market
    • 42,070 miles
    • No accidents, 2 owners, personal use
    • 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from MD to MS*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Gaithersburg, MD / 719 miles away from Tupelo, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHC81F26M5047013
    Stock: 27528473
    Certified Pre-Owned: No

    • 103,294 miles
    • Issue reported, 2 owners, personal use
    • 21 City / 30 Hwy MPG
    • City Auto Memphis (93 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Memphis, TN / 93 miles away from Tupelo, MS

    Vehicle DetailsDiscover the exceptional blend of luxury and performance with this pre-owned 2019 Lexus IS 300 F SPORT. Engineered with precisi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    26 Combined MPG (21 City/30 Highway)

    Listing Information:

    VIN: JTHBA1D26K5094736
    Stock: 510990
    Certified Pre-Owned: No
    Listed since: 06-19-2025

  • Price Drop
    $20,295
    great price
    $2,410 below market
    • 104,379 miles
    • No accidents, 1 owner, personal use only
    • 19 City / 26 Hwy MPG
    • Nissan of Olathe (465 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Olathe, KS / 465 miles away from Tupelo, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHC81D27J5027349
    Stock: SC263032A
    Certified Pre-Owned: No
    Listed since: 06-03-2025

  • New Listing
    Stock photo**
    • 90,510 miles
    • No accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Excellence Auto Direct (495 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Euless, TX / 495 miles away from Tupelo, MS

    Excellence Auto Direct is proud to present you with another True Market Priced Pre-Owned Vehicle. This 2021 Lexus IS 300 is loaded with the following ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: Yes

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHAA1D20M5112307
    Stock: 112307
    Certified Pre-Owned: No
    Listed since: 07-09-2025

    • 117,625 miles
    • 2 accidents, 1 owner, personal use
    • 21 City / 31 Hwy MPG
    • Used Imports Auto Lawrenceville (266 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Lawrenceville, GA / 266 miles away from Tupelo, MS

    EXPERIENCE AMAZING! THE 2021 LEXUS IS300. ATOMIC SILVER ON RED. PWR WINDOWS. PWR DOOR LOCKS. PWR STEERING. PWR MIRRORS. KEYLESS ENTRY. KEYLESS START. ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHAA1D23M5110275
    Stock: LC110275
    Certified Pre-Owned: No
    Listed since: 03-22-2025

    • 77,052 miles
    • 1 accident, 1 owner, personal use only
    • 21 City / 31 Hwy MPG
    • Allan Vigil's Ford (255 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Morrow, GA / 255 miles away from Tupelo, MS

    CARFAX One-Owner. 2021 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged Electronic Stability Control, Exterior Parking Camera Rear, Heated door...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHAA1D20M5111951
    Stock: SGL03476A
    Certified Pre-Owned: No
    Listed since: 06-26-2025

  • New Listing
    • 76,253 miles
    • 1 accident, 2 owners, personal use
    • 21 City / 30 Hwy MPG
    • Carvana - Dallas (477 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 477 miles away from Tupelo, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    26 Combined MPG (21 City/30 Highway)

    Listing Information:

    VIN: JTHBA1D29K5091992
    Stock: 2003871146
    Certified Pre-Owned: No
    Listed since: 07-11-2025

  • New Listing
    • 38,352 miles
    • 21 City / 31 Hwy MPG
    • EchoPark Automotive (452 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Charlotte, NC / 452 miles away from Tupelo, MS

    --CLEAN CARFAX--ONE OWNER-- Come see this 2021 Lexus IS IS 300 featuring Front Collision Mitigation, Blind Spot Monitor, Cross-Traffic Alert, Lane Dep...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D24M5110455
    Stock: TM5110455
    Certified Pre-Owned: No
    Listed since: 07-10-2025

Showing 127 - 147 out of 329 listings

Consumer Reviews for the Lexus IS 300

Read recent reviews for the Lexus IS 300
Overall Consumer Rating
4.6 out of 5 stars28 Reviews
Write a vehicle reviewSee all 28 reviews
  • 5 star
    (68%)
  • 4 star
    (25%)
  • 3 star
    (4%)
  • 2 star
    (4%)
  • 1 star
    (0%)
4 out of 5 stars

Fun 2 drive, poor technology

Jason burgos, 08/08/2018
2018 Lexus IS 300 4dr Sedan AWD (3.5L 6cyl 6A)
Only 3,000 miles in but the navigation and Lexus Enform is terribly unreliable. I wasted money upgrading to this option. Seat cooling and heating has a mind of its own.
Report abuse

Used 2021 Lexus IS 300 in Tupelo, MS Values

Estimated values
2021 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$22,659$24,478$26,306
Clean$22,220$23,982$25,749
Average$21,488$23,155$24,822
Rough$20,537$22,081$23,617

The average list price of a used 2021 Lexus IS 300 in Tupelo, Mississippi is $31,429. The average mileage on a used Lexus IS 300 2021 for sale in Tupelo, Mississippi is 53,447. Based on the average mileage of 53,447 for used 2021 Lexus IS 300 for sale in Tupelo, MS and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 300 2021 in Tupelo, Mississippi to be $21,488.

Filters
Skip to Results

Applied Filters4Active

Select Buying Experience

Location

Search radius500 miles
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Trim

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details


* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.