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1,523 listings
- New Listing
- 32,440 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Polar Mazda (242 mi away)
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Located in White Bear Lake, MN / 242 miles away from Des Moines, IA
At Walser, you’ll get an exceptional car-buying experience. Our *streamlined process* means you’ll work with one dedicated customer specialist to help...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC354353
Stock: 23M1668T
Certified Pre-Owned: No
Listed since: 09-19-2025 - 29,707 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Inver Grove Toyota (229 mi away)
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Located in Inver Grove Heights, MN / 229 miles away from Des Moines, IA
Caviar 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24VRecent Arrival! 19/26 City/Highway MPG
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA9NC335948
Stock: A14683
Certified Pre-Owned: No
Listed since: 07-07-2025- 59,654 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (302 mi away)
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Located in Glenview, IL / 302 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX.Certified. L/Certified Details: * Vehicle History * Warranty Deductible: $0 * CERTIFIED WARRANTY: Unlimited-mi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC326003
Stock: P1785
Certified Pre-Owned: Yes
Listed since: 08-18-2025- New Listing
- 38,186 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Springfield (242 mi away)
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Located in Springfield, IL / 242 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA8NC342646
Stock: 27243236
Certified Pre-Owned: No - 51,183 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Zimmerman Honda (165 mi away)
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Located in Moline, IL / 165 miles away from Des Moines, IA
*Take a look at this good looking 2022 Lexus RX 350 AWD!* Fully powered with seat memory, integrated navigation, AM/FM stereo, satellite radio, USB, b...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC333550
Stock: S1114C
Certified Pre-Owned: No
Listed since: 09-10-2025- Price Drop
- 44,274 miles
- No accidents, 3 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Carmel Auto Gallery (408 mi away)
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Located in Carmel, IN / 408 miles away from Des Moines, IA
Clean CARFAX. Atomic Silver 2020 Lexus RX 350 FWD 8-Speed Automatic 3.5L V6 DOHC 24V RX 350, 4D Sport Utility, 3.5L V6 DOHC 24V, 8-Speed Automatic, F...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA2LC166969
Stock: V66969
Certified Pre-Owned: No
Listed since: 07-21-2025 - 73,590 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Bergstrom Auto (344 mi away)
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Located in Green Bay, WI / 344 miles away from Des Moines, IA
Recent Arrival! 2022 Lexus RX 350 CARFAX One-Owner. Clean CARFAX. Eminent White Pearl AWD 3.5L V6 DOHC 24V 19/26 City/Highway MPG Bergstrom Lexus of A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC332792
Stock: 250549A
Certified Pre-Owned: No
Listed since: 08-29-2025- 49,852 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Lexus Safety System Plus**, ** Lane De...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA6NC318945
Stock: 251364A
Certified Pre-Owned: Yes
Listed since: 07-31-2025- 52,348 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Victory Toyota of St. Louis (274 mi away)
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Located in Saint Louis, MO / 274 miles away from Des Moines, IA
This **luxurious** 2022 Lexus RX 350 with **52k miles** was a **privately acquired vehicle** here at Victory Toyota St. Louis. Known for its refined r...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC349793
Stock: 86E09501
Certified Pre-Owned: No
Listed since: 09-05-2025- Price Drop
- 42,770 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 350 8-Speed Automatic AWDColor Head Up Display!Luxury Package!Pa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDAXNC342634
Stock: 28749A
Certified Pre-Owned: Yes
Listed since: 09-12-2025 - Price Drop
- 87,631 miles
- Frame damage reported, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- AutoGiant USA (411 mi away)
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Located in Indianapolis, IN / 411 miles away from Des Moines, IA
Silver 2020 Lexus RX 350 FWD 3.5L V6 DOHC 24V 8-Speed Automatic*CARPLAY*, *LEATHER SEATS*, *BACKUP CAMERA*, *LOCAL HOME DELIVERY AVAILABLE!*, Black Ar...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Issue reported
Salvage Vehicle: No
Frame Damage: Yes
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA8LC158889
Stock: K158889
Certified Pre-Owned: No
Listed since: 08-15-2025 - 90,234 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
F Sport Package!12.3" Touchscreen Navigation!Blind Spot Monitor with Intuitive Parking Assist!Rear Cross-Traffic Braking!**Blind Spot Monitor*...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA3LC251006
Stock: PWS2819
Certified Pre-Owned: No
Listed since: 09-15-2025- Price Drop
- 60,440 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
Close
Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Ultra White 2022 Lexus RX 350 F Sport Handling 8-Speed Automatic AWD19/26 City/Highway MPGCold Wea...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA8NC322431
Stock: PWS2818
Certified Pre-Owned: No
Listed since: 09-15-2025 - Price Drop
- 54,715 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- CarWise Gurnee (296 mi away)
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Located in Gurnee, IL / 296 miles away from Des Moines, IA
AWD.Recent Arrival! Clean CARFAX. Odometer is 1206 miles below market average! Black 2020 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V 19/26 City...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5LC251654
Stock: GL29713
Certified Pre-Owned: No
Listed since: 09-10-2025 - New ListingNot Priced
- 33,804 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Highland Park (301 mi away)
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Located in Highland Park, IL / 301 miles away from Des Moines, IA
2022 Lexus RX 350 Silver AWD 3.5L V6 DOHC 24VOur process of Lexus Complete offers a seamless buying experience with upfront pricing and a single po...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC368367
Stock: 251026A
Certified Pre-Owned: No
Listed since: 09-22-2025 - New Listing
- 22,516 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA9NC365679
Stock: Q3694
Certified Pre-Owned: No
Listed since: 09-23-2025 - New Listing
- 42,768 miles
- 1 accident, 3 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Memphis (487 mi away)
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Located in Memphis, TN / 487 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0LC250721
Stock: 27219226
Certified Pre-Owned: No - 45,270 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Patriot Chrysler Dodge Jeep Ram of Tulsa (398 mi away)
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Located in Tulsa, OK / 398 miles away from Des Moines, IA
GREAT PRICE ALERT!! Welcome to Patriot CDJR of Tulsa! We are here to provide the absolute best selection, best prices, and best service in Oklahoma!! ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC339616
Stock: PTTM293
Certified Pre-Owned: No
Listed since: 08-20-2025- New Listing
- 64,084 miles
- 2 accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax Jackson (TN) (484 mi away)
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Located in Jackson, TN / 484 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA1LC176537
Stock: 27643702
Certified Pre-Owned: No - 46,827 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Chandler Chevrolet (476 mi away)
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Located in Madison, IN / 476 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA1LC177140
Stock: T6304A
Certified Pre-Owned: No
Listed since: 06-28-2025- New Listing
- 41,712 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC357414
Stock: Q3695
Certified Pre-Owned: No
Listed since: 09-23-2025
Showing 85 - 105 out of 1,523 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $32,204 | $34,258 | $36,399 |
| Clean | $31,775 | $33,783 | $35,876 |
| Average | $31,060 | $32,993 | $35,004 |
| Rough | $30,130 | $31,964 | $33,870 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $40,123. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 50,667. Based on the average mileage of 50,667 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $31,060.
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