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1,523 listings
- New Listing
- 54,064 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
19/26 City/Highway MPG Mungenast Makes the Difference. Silver 2022 Lexus RX 350 F Sport Handling AWD 8-Speed Automatic 3.5L V6 DOHC 24V Please call 31...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA2NC367283
Stock: P1486
Certified Pre-Owned: No
Listed since: 09-05-2025 - Price Drop$43,999great price$3,535 below market
- 47,802 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Maplewood (240 mi away)
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Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner and No Accidents, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, P...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA4PC035427
Stock: RSL291234A
Certified Pre-Owned: Yes
Listed since: 07-30-2025 - New ListingNot Priced
- 36,157 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Auto Campus (329 mi away)
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Located in Wichita, KS / 329 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC322140
Stock: 54L1006LR
Certified Pre-Owned: No
Listed since: 09-22-2025 - New Listing$42,995fair price$15 above market
- 62,363 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Baha Auto (305 mi away)
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Located in Chicago, IL / 305 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC317551
Stock: N23024
Certified Pre-Owned: No - New ListingNot Priced
- 84,029 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Glenn Chrysler Dodge Jeep Ram (487 mi away)
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Located in Crestwood, KY / 487 miles away from Des Moines, IA
Gray Pearl 2020 Lexus RX 350 AWD 3.5L V6 DOHC 24V 8-Speed AutomaticTHIS VEHICLES FEATURES INCLUDE:, AWD.Recent Arrival!
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0LC221932
Stock: 620868A
Certified Pre-Owned: No
Listed since: 09-23-2025 - Price Drop$37,495great price$3,159 below market
- 52,069 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Kenny Kent Lexus of Evansville (410 mi away)
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Located in Evansville, IN / 410 miles away from Des Moines, IA
*** Premium Package *** Apple Carplay *** Android Auto *** 20' Dark Silver Alloy Wheels *** 12.3' Screen with Premium Audio *** Panoramic View Monitor...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8MC302808
Stock: 2530794A
Certified Pre-Owned: Yes
Listed since: 08-22-2025 - $49,999good price$3,416 below market
- 13,956 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Rosen Hyundai of Algonquin (275 mi away)
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Located in Algonquin, IL / 275 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price! Iridium 2023 Lexus RX 350 F Sport Handling AWD 8-Speed Automatic 2.4L I4 PDI Turbocharged DOHC 16V LEV3-SULEV30 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7PC009226
Stock: Q37452A
Certified Pre-Owned: No
Listed since: 07-19-2025 - $48,900good price$3,722 below market
- 20,570 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 22 City / 29 Hwy MPG
- Volkswagen of Downtown Chicago (310 mi away)
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Located in Chicago, IL / 310 miles away from Des Moines, IA
Our One Owner 2023 Lexus RX 350 Premium is engineered to invoke impressive power and grace in Caviar! Powered by a TurboCharged 2.4 Liter 4 Cylinder o...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
25 Combined MPG (22 City/29 Highway)
Listing Information:
VIN: 2T2BAMBA5PC001255
Stock: 1255K
Certified Pre-Owned: No
Listed since: 08-26-2025 - $32,962great price$2,394 below market
- 71,676 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Heller Motors (263 mi away)
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Located in Pontiac, IL / 263 miles away from Des Moines, IA
AWD, BACK UP CAMERA, POWER SEATS, POWER WINDOWS AND POWER LOCKS! REMOTE START, REMOTE TRUNK RELEASE, LED HEADLIGHTS, SATELLITE RADIO, CHILD SAFETY...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7MC284317
Stock: U9915A
Certified Pre-Owned: No
Listed since: 07-02-2025 - Price Drop$50,555good price$3,109 below market
- 10,094 miles
- No accidents, 2 owners, personal use
- 5 Seats, 22 City / 29 Hwy MPG
- BMW of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2023 Lexus RX 350 Caviar Odometer is 16619 miles below market average! Clean CARFAX.Palomino w/Ash Bamboo w/Leather Seat Trim, Cold Area Package, Navi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
25 Combined MPG (22 City/29 Highway)
Listing Information:
VIN: JTJCHMAA4P2004004
Stock: PJ61247A
Certified Pre-Owned: No
Listed since: 07-18-2025 - 63,455 miles
- No accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Baha Auto (301 mi away)
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Located in Palos Hills, IL / 301 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC339306
Stock: S32019
Certified Pre-Owned: No- New Listing$38,990fair price
- 22,697 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Dallas, TX / 631 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA2MC184369
Stock: 2003914634
Certified Pre-Owned: No
Listed since: 08-02-2025 - $46,000good price$1,994 below market
- 34,341 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Highland Park (301 mi away)
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Located in Highland Park, IL / 301 miles away from Des Moines, IA
Experience refined luxury and confidence on the road with this L/Certified 2023 Lexus RX 350 Premium AWD, showing just 34,341 miles. Backed by a clean...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8PC011499
Stock: 250717A
Certified Pre-Owned: Yes
Listed since: 08-05-2025 - $49,910good price$2,576 below market
- 12,195 miles
- No accidents, 2 owners, rental vehicle
- 5 Seats, 21 City / 28 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA9PC032846
Stock: P1414
Certified Pre-Owned: Yes
Listed since: 07-02-2025 - $57,000good price$3,334 below market
- 25,328 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2023 Lexus RX 350 Luxury Clean CARFAX. CARFAX One-Owner. **ACCIDENT FREE CARFAX**, **BLUETOOTH**, **CARFAX ONE OWNER**, **ELECTRONIC STABILITY CONTROL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8PC010420
Stock: S046956A
Certified Pre-Owned: Yes
Listed since: 09-01-2025 - $55,490fair price$170 below market
- 29,606 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Eminent White Pearl 2023 Lexus RX 350 Luxury **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERV...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA3PC030932
Stock: U4782
Certified Pre-Owned: Yes
Listed since: 08-12-2025 - $54,990fair price$1,240 above market
- 12,413 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Hubler Acura (418 mi away)
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Located in Greenwood, IN / 418 miles away from Des Moines, IA
CARFAX 1-Owner, ONLY 12,413 Miles! $2,500 below J.D. Power Retail!, EPA 28 MPG Hwy/21 MPG City! Heated/Cooled Seats, NAV, Sunroof, Remote Engine Start...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7PC019318
Stock: 24630A
Certified Pre-Owned: No
Listed since: 08-12-2025 - $53,910fair price$1,847 below market
- 16,004 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 22 City / 29 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+, Lexus Enform ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
25 Combined MPG (22 City/29 Highway)
Listing Information:
VIN: 2T2BAMBA9PC021346
Stock: P1416
Certified Pre-Owned: Yes
Listed since: 07-03-2025 - $50,000good price$2,984 below market
- 20,686 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2023 Lexus RX 350 Premium **BLUETOOTH**, **CARFAX ONE OWNER**, **ELECTRONIC STABILITY CONTROL**, **HEATED MIRRORS**, **HEATED SEATS**, **HEATED STEERI...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCAXPC037490
Stock: C113963A
Certified Pre-Owned: Yes
Listed since: 08-21-2025 - $50,910fair price$688 below market
- 5,704 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
Close
Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Heads Up Display, Blind Spot Monitoring, Le...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA6PC007659
Stock: P1415
Certified Pre-Owned: Yes
Listed since: 07-03-2025 - Price Drop$48,499fair price$67 above market
- 27,025 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Maplewood (240 mi away)
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Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner, AWD, F-Sport, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, Parking A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCAXPC021161
Stock: PFD19498
Certified Pre-Owned: Yes
Listed since: 08-08-2025
Showing 106 - 126 out of 1,523 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 F SPORT 4dr SUV AWD w/Handling Package (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $36,528 | $38,719 | $41,005 |
| Clean | $36,041 | $38,183 | $40,415 |
| Average | $35,230 | $37,289 | $39,433 |
| Rough | $34,176 | $36,127 | $38,155 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $47,417. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 34,392. Based on the average mileage of 34,392 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $35,230.
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