Skip to FiltersReport abuse
1,523 listings
- $31,995fair price$225 above market
- 97,854 miles
- 1 accident, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Baha Auto (301 mi away)
Close
Located in Palos Hills, IL / 301 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA8MC273848
Stock: S32080
Certified Pre-Owned: No - Price Drop$43,499good price$2,336 below market
- 31,062 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Maplewood (240 mi away)
Close
Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner and No Accidents, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front and Rear Seats, Heated Steering...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC322731
Stock: PRH19502
Certified Pre-Owned: Yes
Listed since: 08-11-2025 - $45,499good price$3,229 below market
- 29,574 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Maplewood (240 mi away)
Close
Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner and No Accident, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, Pr...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC363084
Stock: L311216A
Certified Pre-Owned: Yes
Listed since: 09-15-2025 - Price Drop$36,995good price$2,700 below market
- 76,989 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (302 mi away)
Close
Located in Glenview, IL / 302 miles away from Des Moines, IA
Recently received and ready for immediate delivery is this one-owner, clean CARFAX, GORGEOUS, PERFECTLY MAINTAINED, Atomic Silver / Black RX350 AWD! M...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC312596
Stock: L251016A
Certified Pre-Owned: Yes
Listed since: 07-31-2025 - $44,495good price$2,649 below market
- 13,839 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Inver Grove Toyota (229 mi away)
Close
Located in Inver Grove Heights, MN / 229 miles away from Des Moines, IA
Caviar 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24VRecent Arrival! 19/26 City/Highway MPG
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA7NC320414
Stock: A14661A
Certified Pre-Owned: No
Listed since: 07-02-2025 - $47,500good price$1,760 below market
- 4,845 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Corwin Chrysler Dodge Jeep RAM FIAT of Springfield (301 mi away)
Close
Located in Springfield, MO / 301 miles away from Des Moines, IA
Recent Arrival! Corwin Chrysler Dodge Jeep Ram Fiat is pleased to offer this. Lexus RX that is well equipped and includes these key features and benef...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC321106
Stock: 3321106
Certified Pre-Owned: No
Listed since: 09-11-2025 - New Listing$35,546good price$2,613 below market
- 46,146 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Beardmore Hyundai (122 mi away)
Close
Located in Bellevue, NE / 122 miles away from Des Moines, IA
Certification Program Details: Beardmore Certified Vehicles include a 6 month or 6,000 miles limited warranty and a 2 year or 100,000 mile powertrain ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4LC215793
Stock: H9160A
Certified Pre-Owned: No
Listed since: 06-19-2025 - Price Drop$38,398good price$2,939 below market
- 26,116 miles
- 1 accident, 2 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- The Internet Car Lot (127 mi away)
Close
Located in Omaha, NE / 127 miles away from Des Moines, IA
Experience luxury and reliability with this 2022 Lexus RX 350 FWD, powered by a smooth 3.5L V6 engine delivering an efficient 20 city / 27 highway MPG...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA8NC250358
Stock: 250358C71384
Certified Pre-Owned: No - New Listing$28,602good price$2,247 below market
- 82,128 miles
- No accidents, 3 owners, corporate fleet vehicle
- 5 Seats, 20 City / 27 Hwy MPG
- Wyatt-Johnson Subaru (484 mi away)
Close
Located in Clarksville, TN / 484 miles away from Des Moines, IA
2020 Moonbeam Beige Metallic Lexus 4D Sport Utility RX 350 8-Speed Automatic 3.5L V6 DOHC 24V FWDBirch w/Semi-Aniline Leather Seat Trim, 3.329 Axle ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA8LC179112
Stock: TLC179112S
Certified Pre-Owned: No
Listed since: 08-16-2025 - Price Drop$43,999good price$2,523 below market
- 36,486 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Maplewood (240 mi away)
Close
Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, Carfax One Owner and No Accidents, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, P...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC363009
Stock: PRH19511
Certified Pre-Owned: Yes
Listed since: 09-03-2025 - Price Drop$42,990good price$1,929 below market
- 20,871 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana - Oklahoma City (472 mi away)
- Home delivery*
Close
Located in Oklahoma City, OK / 472 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC250920
Stock: 2003575564
Certified Pre-Owned: No
Listed since: 09-17-2025 - Price Drop$38,908good price$2,514 below market
- 42,833 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Toyota of Brookfield (297 mi away)
Close
Located in Brookfield, WI / 297 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX. Eminent White Pearl 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V AWD, Parchment w/NuLuxe Seat Trim, Cold A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC359448
Stock: P84234
Certified Pre-Owned: No
Listed since: 08-23-2025 - Price Drop$35,827fair price$1,139 above market
- 62,628 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Stew Hansen Buick GMC (6 mi away)
Close
Located in Clive, IA / 6 miles away from Des Moines, IA
2022 Lexus RX 350 AWD - CarBravo Certified Luxury & All-Weather Capability!Experience elegance, power, and peace of mind with this 2022 Lexus RX 350 A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA6NC312059
Stock: 31721
Certified Pre-Owned: No
Listed since: 08-07-2025 - $38,697good price$1,887 below market
- 35,606 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- EchoPark Automotive St. Louis (255 mi away)
Close
Located in Chestefield, MO / 255 miles away from Des Moines, IA
At EchoPark, it’s all about offering you options for a happy experience. We have thousands of new-to-you makes and models that range from sedans to tr...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC359025
Stock: PNC359025
Certified Pre-Owned: No
Listed since: 07-17-2025 - Price Drop$38,990fair price$1,333 below market
- 22,810 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana - Chicago (273 mi away)
- Home delivery*
Close
Located in Chicago, IL / 273 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5LC216523
Stock: 2004064172
Certified Pre-Owned: No
Listed since: 09-12-2025 - Price Drop$44,243fair price$289 below market
- 22,159 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Acura of Westmont (293 mi away)
Close
Located in Westmont, IL / 293 miles away from Des Moines, IA
Silver 2022 Lexus RX 350 F Sport AWD 8-Speed Automatic 3.5L V6 DOHC 24V. $4035 IN ADDED OPTIONS! **ONE OWNER**, **ACCIDENT FREE CARFAX**, **AWD**, *N...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC339886
Stock: PJ12450
Certified Pre-Owned: No
Listed since: 07-18-2025 - $41,998good price$2,238 below market
- 53,053 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wichita (329 mi away)
Close
Located in Wichita, KS / 329 miles away from Des Moines, IA
2022 Lexus RX 350 AWD, located at Lexus of Wichita. Original MSRP $56,775. Matador Red Mica with Parchment Leather interior. L/Certified provides up t...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC316358
Stock: 54L1345T
Certified Pre-Owned: Yes
Listed since: 08-23-2025 - $42,716fair price$398 above market
- 39,782 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Eddy's Toyota of Wichita (332 mi away)
Close
Located in Wichita, KS / 332 miles away from Des Moines, IA
**ONE OWNER**, **CLEAN AutoCheck**, Back-Up Camera, All-Wheel Drive, Navigation, Heated Seats, Ventilated Seats, Leather Seats, Premium Sound System, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC338110
Stock: IT44911
Certified Pre-Owned: No
Listed since: 08-12-2025 - Price Drop$41,249fair price$1,461 above market
- 48,107 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Burnsville Toyota (218 mi away)
Close
Located in Burnsville, MN / 218 miles away from Des Moines, IA
*CLEAN 1-OWNER CARFAX*, *CRUISE CONTROL*, *HEATED FRONT SEATS*, LEATHER SEATS*, BACKUP CAMERA*, MOONROOF*, ALLOY WHEELS*, BLUETOOTH*, RX 350, AWD. Cle...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC317293
Stock: 1036670
Certified Pre-Owned: No
Listed since: 08-05-2025 - $44,990fair price$2 below market
- 22,237 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Concept Motors (335 mi away)
Close
Located in Sheboygan, WI / 335 miles away from Des Moines, IA
CLEAN CARFAX! ONE-OWNER! THIS 2022 RX 350 NOT ONLY HAS LOW MILES, BUT ALSO SEVERAL ADDITIONAL FACTORY-INSTALLED OPTIONS! PREMIUM PACKAGE, PANORAMIC SU...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC335288
Stock: A1131
Certified Pre-Owned: No
Listed since: 04-18-2025 - $32,025good price$1,545 below market
- 101,498 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Patriot Chrysler Dodge Jeep Ram of Tulsa (398 mi away)
Close
Located in Tulsa, OK / 398 miles away from Des Moines, IA
GREAT PRICE ALERT!! Welcome to Patriot CDJR of Tulsa! We are here to provide the absolute best selection, best prices, and best service in Oklahoma!! ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC233637
Stock: PTDP056
Certified Pre-Owned: No
Listed since: 07-15-2025
Showing 22 - 42 out of 1,523 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2021 Lexus RX 350 in Des Moines, IA Values
Estimated values
2021 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $32,508 | $34,733 | $36,962 |
| Clean | $32,001 | $34,182 | $36,365 |
| Average | $31,154 | $33,263 | $35,371 |
| Rough | $30,054 | $32,068 | $34,079 |
The average list price of a used 2021 Lexus RX 350 in Des Moines, Iowa is $39,960. The average mileage on a used Lexus RX 350 2021 for sale in Des Moines, Iowa is 43,649. Based on the average mileage of 43,649 for used 2021 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2021 in Des Moines, Iowa to be $31,154.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.