Skip to FiltersReport abuse
1,779 listings
- $27,117great price$3,158 below market
- 88,939 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Sapaugh GM Country (287 mi away)
Close
Located in Herculaneum, MO / 287 miles away from Des Moines, IA
** We are 15 minutes south of St. Louis. Everyone leaves happy! Priced below KBB Fair Purchase Price! Atomic Silver 2020 Lexus RX 350 AWD 8-Speed Auto...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5LC219447
Stock: 2541831
Certified Pre-Owned: No
Listed since: 02-12-2025 - Price Drop$44,498good price$3,152 below market
- 16,414 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Husker GMC Chevrolet Cadillac (168 mi away)
Close
Located in Lincoln, NE / 168 miles away from Des Moines, IA
Experience the Road with Unmatched Sophistication and Power in the 2022 Lexus RX 350Discover the perfect blend of luxury and performance with the 2...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC322463
Stock: Z58194A
Certified Pre-Owned: No
Listed since: 05-17-2025 - Price Drop$43,999good price$1,801 below market
- 21,393 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (233 mi away)
Close
Located in Wayzata, MN / 233 miles away from Des Moines, IA
Treat yourself to Lexus Certified ownership privileges:161-point inspection by expert Lexus technicians ensures exemplary condition24/7 Roadside As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC312965
Stock: PRH441
Certified Pre-Owned: Yes
Listed since: 04-18-2025 - $41,000good price$1,775 below market
- 22,596 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Louisville (487 mi away)
Close
Located in Louisville, KY / 487 miles away from Des Moines, IA
2020 Lexus RX 350 **UNIQUE OPPORTUNITY**, **LEXUS OF A LIFETIME**, **BLUETOOTH**, **ELECTRONIC STABILITY CONTROL**, **FUEL EFFICIENT**, **HEATED MIRRO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6LC212376
Stock: P212376
Certified Pre-Owned: Yes
Listed since: 04-25-2025 - $43,309good price$2,239 below market
- 32,713 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (308 mi away)
Close
Located in Milwaukee, WI / 308 miles away from Des Moines, IA
Navigation system!Power rear door with kick sensor! Heated leather steering wheel!Heated and ventilated seats!Premium package!Certified. CAR...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC351999
Stock: PRS7971
Certified Pre-Owned: Yes
Listed since: 04-22-2025 - $47,995good price$3,290 below market
- 25,294 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)
Close
Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 350 F Sport Handling CARFAX One-Owner. Recent Arrival! AWD 8-Speed Automatic 4D Sport Utility Atomic SilverL/Certified Deta...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA5NC352647
Stock: AL2076P
Certified Pre-Owned: Yes
Listed since: 06-01-2025 - $47,998good price$3,255 below market
- 23,118 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
2022 Lexus RX 350, Lexus Certified Pre-Owned. Located at Lexus of Wichita. Original MSRP $57,840. Caviar with Parchment interior. L/Certified provides...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC356360
Stock: 54L1069P
Certified Pre-Owned: Yes
Listed since: 03-17-2025 - New Listing$38,990good price$2,339 below market
- 14,197 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana - Oklahoma City (474 mi away)
- Home delivery*
Close
Located in Oklahoma City, OK / 474 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXLC221131
Stock: 2003686060
Certified Pre-Owned: No
Listed since: 04-30-2025 - Price Drop$44,595fair price$768 below market
- 19,367 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Napleton Chevrolet St. Charles (274 mi away)
Close
Located in Saint Charles, IL / 274 miles away from Des Moines, IA
The Napleton Auto Group promotes a no pressure buying experience that puts the customer in charge of the buying process, and for over 80 years, the Na...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA6NC329489
Stock: P582
Certified Pre-Owned: No
Listed since: 04-28-2025 - $44,995good price$2,685 below market
- 30,622 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (286 mi away)
Close
Located in Schaumburg, IL / 286 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Bought and Serviced Here**, **Lexus Sa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC337476
Stock: 250938A
Certified Pre-Owned: Yes
Listed since: 06-04-2025 - $48,988good price$2,250 below market
- 10,305 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (307 mi away)
Close
Located in Chicago, IL / 307 miles away from Des Moines, IA
Recent Arrival! Atomic Silver 2022 Lexus RX 350 **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPLE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC368725
Stock: S1202A
Certified Pre-Owned: Yes
Listed since: 05-27-2025 - $43,672good price$3,094 below market
- 9,722 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Bob Rohrman Toyota (362 mi away)
Close
Located in Lafayette, IN / 362 miles away from Des Moines, IA
CARFAX One-Owner. *Bluetooth, Hands-Free, Birch w/NuLuxe Seat Trim, 12.3" Navigation System w/Mark Levinson Audio, 18" x 8" Aluminum Wheels, AM/FM rad...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC250653
Stock: LT1111S
Certified Pre-Owned: No
Listed since: 05-13-2025 - Price Drop$38,995fair price$467 below market
- 52,273 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Arlington (290 mi away)
Close
Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 350 Automatic, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for this Value!, H...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA8NC235553
Stock: AL2153P
Certified Pre-Owned: Yes
Listed since: 04-19-2025 - Price Drop$45,250good price$2,439 below market
- 20,127 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Principle Toyota (497 mi away)
Close
Located in Memphis, TN / 497 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX. Heated Seats, Balance of Factory Warranty, Blind Spot Monitor, Back Up Camera, Heated and Cooled Seats, Bluetooth / Ha...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC230697
Stock: NC230697P
Certified Pre-Owned: No
Listed since: 05-12-2025 - $47,995good price$1,930 below market
- 22,160 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (286 mi away)
Close
Located in Schaumburg, IL / 286 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Bought and Serviced Here**, **Lexus Sa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC332251
Stock: 250908A
Certified Pre-Owned: Yes
Listed since: 05-31-2025 - $50,930fair price$333 below market
- 14,937 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (265 mi away)
Close
Located in Manchester, MO / 265 miles away from Des Moines, IA
L/CERTIFIED, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+, Lexus Enfo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA9NC359181
Stock: P1362
Certified Pre-Owned: Yes
Listed since: 05-01-2025 - $46,500fair price$1,586 above market
- 22,237 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Concept Motors (333 mi away)
Close
Located in Sheboygan, WI / 333 miles away from Des Moines, IA
CLEAN CARFAX! ONE-OWNER! THIS 2022 RX 350 NOT ONLY HAS LOW MILES, BUT ALSO SEVERAL ADDITIONAL FACTORY-INSTALLED OPTIONS! PREMIUM PACKAGE, PANORAMIC SU...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC335288
Stock: A1131
Certified Pre-Owned: No
Listed since: 04-18-2025 - $42,998good price$2,499 below market
- 44,917 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Nissan Wayzata (233 mi away)
Close
Located in Wayzata, MN / 233 miles away from Des Moines, IA
At Walser, you’ll get an exceptional car-buying experience. Our *streamlined process* means you’ll work with one dedicated customer specialist to help...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC366720
Stock: 24N1297P
Certified Pre-Owned: No
Listed since: 05-07-2025 - $46,995good price$1,619 below market
- 26,415 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (300 mi away)
Close
Located in Glenview, IL / 300 miles away from Des Moines, IA
JUST IN! This one-owner, clean CARFAX, GORGEOUS, Atomic Silver / Black RX350 AWD! And it's LOADED! With premium, cold weather and navigation packages,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC362285
Stock: L25903A
Certified Pre-Owned: Yes
Listed since: 05-22-2025 - $47,697fair price$901 below market
- 26,905 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)
Close
Located in Orland Park, IL / 298 miles away from Des Moines, IA
Matador Red Mica 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V NAVIGATION!, BOUGHT HERE SERVICED HERE!, LOCAL TRADE!, ONE OWNER!, GREAT VEH...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC366877
Stock: LX07251
Certified Pre-Owned: Yes
Listed since: 05-31-2025 - Price Drop$34,500good price$1,626 below market
- 77,049 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (295 mi away)
- Five Star Dealer
Close
Located in Brookfield, WI / 295 miles away from Des Moines, IA
**L/Certified and 3500 lbs Tow Prep Package (Engine & Transmission Oil Coolers and Heavy-Duty Radiator), Cold Weather Package, Premium Package, AWD, B...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4LC216877
Stock: 28263A
Certified Pre-Owned: Yes
Listed since: 05-28-2025
Showing 22 - 42 out of 1,779 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2020 Lexus RX 350 in Des Moines, IA Values
Estimated values
2020 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $30,200 | $33,159 | $36,003 |
| Clean | $29,651 | $32,552 | $35,341 |
| Average | $28,735 | $31,541 | $34,236 |
| Rough | $27,544 | $30,226 | $32,801 |
The average list price of a used 2020 Lexus RX 350 in Des Moines, Iowa is $43,763. The average mileage on a used Lexus RX 350 2020 for sale in Des Moines, Iowa is 29,605. Based on the average mileage of 29,605 for used 2020 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2020 in Des Moines, Iowa to be $28,735.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.