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1,779 listings
- Price Drop$40,880good price$1,508 below market
- 33,745 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Zeigler Buick GMC of Lincolnwood (304 mi away)
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Located in Lincolnwood, IL / 304 miles away from Des Moines, IA
2022 Lexus RX 350 Nightfall Mica NAVIGATION w/BACKUP CAMERA*, BLUETOOTH w/MUSIC STREAMING*, BLIND SPOT MONITOR*, PRE-COLLSION WARNING SYSTEM*, LANE DE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC244889
Stock: B25284A
Certified Pre-Owned: No
Listed since: 05-04-2025 - $40,500good price$1,959 below market
- 45,771 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 350 Automatic, AWD/4WD, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for this ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC336189
Stock: AL3840A
Certified Pre-Owned: Yes
Listed since: 05-27-2025 - New Listing$45,000good price$2,742 below market
- 46,763 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Louisville (487 mi away)
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Located in Louisville, KY / 487 miles away from Des Moines, IA
2022 Lexus RX 350 F Sport Handling Clean CARFAX. CARFAX One-Owner. **ACCIDENT FREE CARFAX**, **BLUETOOTH**, **CARFAX ONE OWNER**, **ELECTRONIC STABILI...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA7NC320685
Stock: 5039673A
Certified Pre-Owned: Yes
Listed since: 06-06-2025 - $44,998fair price$585 below market
- 30,395 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Auto Campus (331 mi away)
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Located in Wichita, KS / 331 miles away from Des Moines, IA
2022 Lexus RX 350 AWD, located at Lexus of Wichita. Original MSRP $58,115. Atomic Silver with Glazed Caramel interior. This 1 owner RX is equipped wit...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC355519
Stock: 54L1013P
Certified Pre-Owned: No
Listed since: 12-18-2024 - New Listing$49,000fair price$372 below market
- 24,028 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Highland Park (299 mi away)
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Located in Highland Park, IL / 299 miles away from Des Moines, IA
2022 Lexus RX 350 F Sport AWD 3.5L V6 DOHC 24VOur process of Lexus Complete offers a seamless buying experience with upfront pricing and a single p...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA9NC354164
Stock: 250611A
Certified Pre-Owned: No
Listed since: 06-10-2025 - New Listing$40,995good price$2,883 below market
- 40,674 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Arlington (290 mi away)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 350 Automatic, Backup Camera, Below Market Price to save you the Negotiating Hassel, BlindSpot Detection, Bluetooth, Cooled S...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA3NC231846
Stock: AL1178S
Certified Pre-Owned: Yes
Listed since: 06-08-2025 - $48,995fair price$88 above market
- 12,092 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (300 mi away)
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Located in Glenview, IL / 300 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX. Odometer is 17825 miles below market average!Certified. L/Certified Details: * Roadside Assistance * Limited Wa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC363429
Stock: L25913A
Certified Pre-Owned: Yes
Listed since: 05-28-2025 - $48,995fair price$787 above market
- 14,881 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (286 mi away)
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Located in Schaumburg, IL / 286 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Bought and Serviced Here**, **Lexus Sa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC352576
Stock: 250885A
Certified Pre-Owned: Yes
Listed since: 06-02-2025 - $44,176fair price$157 below market
- 30,039 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- AutoCenters Nissan (287 mi away)
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Located in Herculaneum, MO / 287 miles away from Des Moines, IA
ONE OWNER with ZERO ACCIDENTS, All Wheel Drive, RX 350 F Sport AWD - Sunroof - Htd/Cooled Leather, 4D Sport Utility, AWD, Ultra White, Circuit Red w/F...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC355116
Stock: R83930
Certified Pre-Owned: No
Listed since: 03-31-2025 - New Listing$42,000fair price$352 below market
- 43,953 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Napleton's Valley Hyundai (278 mi away)
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Located in Aurora, IL / 278 miles away from Des Moines, IA
One Owner, Clean Car Fax, 2022 Lexus RX 350 F Sport in Black, AWD, 20" x 8" Aluminum Wheels, 3.33 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, ABS bra...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC356539
Stock: KBB1636
Certified Pre-Owned: No
Listed since: 06-06-2025 - $44,940good price$1,938 below market
- 42,338 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (265 mi away)
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Located in Manchester, MO / 265 miles away from Des Moines, IA
Panoramic View Monitor, L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Leather Seats, Backup Camera, Power Sunroof, Heated/Ventilated seats, Premi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC357108
Stock: 35376A
Certified Pre-Owned: Yes
Listed since: 05-30-2025 - Price Drop$40,400good price$1,373 below market
- 49,133 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (308 mi away)
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Located in Milwaukee, WI / 308 miles away from Des Moines, IA
Navigation system!20" dark silver alloy wheels with machined finish!Heated and ventilated front seats!Heated steering wheel!Power rear door wi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7NC339091
Stock: L20913A
Certified Pre-Owned: Yes
Listed since: 05-21-2025 - Price Drop$32,998fair price$24 above market
- 73,909 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mercedes-Benz of Louisville (487 mi away)
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Located in Louisville, KY / 487 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price!Eminent White Pearl 2020 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V AWD, Birch w/Semi-Aniline Leather Se...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7LC227811
Stock: 372775A
Certified Pre-Owned: No
Listed since: 04-28-2025 - New Listing$46,999fair price$672 below market
- 18,987 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (233 mi away)
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Located in Wayzata, MN / 233 miles away from Des Moines, IA
Recent Arrival! CARFAX One-Owner. Certified. Atomic Silver 2022 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V AWD 19/26 City/Highway MPG Odometer is ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC350016
Stock: PRS480
Certified Pre-Owned: Yes
Listed since: 06-07-2025 - Price Drop$45,400fair price$403 above market
- 17,348 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (233 mi away)
- Home delivery*
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Located in Minnetonka, MN / 233 miles away from Des Moines, IA
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Ste...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC356213
Stock: S9001033A
Certified Pre-Owned: No - $45,990fair price$1,237 above market
- 22,024 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (321 mi away)
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Located in Merrillville, IN / 321 miles away from Des Moines, IA
UNLIMITED MILE COMPREHENSIVE WARRANTY THRU 12/23/2027!, PANORAMIC GLASS MOONROOF!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC326412
Stock: PM2714
Certified Pre-Owned: Yes
Listed since: 03-28-2025 - $38,500fair price$517 below market
- 47,285 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Unlimited Motors Elwood (415 mi away)
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Located in Elwood, IN / 415 miles away from Des Moines, IA
Navigation, Back Up Camera, Sunroof, Bluetooth, Touch Screen, Power Lift Gate, Apple Car Play, Blind Spot, 1-Owner, Clean Carfax, Low Miles, Lane Assi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2SZMAA1NC219247
Stock: STK219247
Certified Pre-Owned: No
Listed since: 10-21-2024 - $36,998fair price$427 below market
- 50,110 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Indianapolis (409 mi away)
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Located in Indianapolis, IN / 409 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1LC223785
Stock: 27351035
Certified Pre-Owned: No - New Listing$33,990fair price$717 below market
- 63,933 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana - Indianapolis (409 mi away)
- Home delivery*
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Located in Indianapolis, IN / 409 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0LC237189
Stock: 2003794880
Certified Pre-Owned: No
Listed since: 06-10-2025 - $45,206fair price$886 above market
- 19,351 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Zeigler Subaru of Lafayette (362 mi away)
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Located in Lafayette, IN / 362 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price! 2022 Lexus Matador Red Mica AWD RX 350 8-Speed Automatic Odometer is 10140 miles below market average! Heated Le...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC308983
Stock: 3933LP
Certified Pre-Owned: No
Listed since: 04-02-2025 - New Listing$48,988good price$2,643 below market
- 23,455 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (307 mi away)
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Located in Chicago, IL / 307 miles away from Des Moines, IA
Recent Arrival! Nightfall Mica 2022 Lexus RX 350 F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC359984
Stock: U4729A
Certified Pre-Owned: Yes
Listed since: 06-06-2025
Showing 43 - 63 out of 1,779 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,637 | $35,050 | $36,523 |
| Clean | $33,189 | $34,564 | $35,998 |
| Average | $32,442 | $33,755 | $35,123 |
| Rough | $31,471 | $32,703 | $33,985 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $43,140. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 35,724. Based on the average mileage of 35,724 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $32,442.
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