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1,779 listings
- Price Drop$33,995good price$1,987 below market
- 80,788 miles
- 2 accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2022 Lexus RX 350 F Sport Automatic, AWD/4WD, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for this Val...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA9NC321214
Stock: AL2136P
Certified Pre-Owned: No
Listed since: 04-01-2025 - Price Drop$37,995fair price$1,036 above market
- 83,049 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2022 Lexus RX 350 F Sport Handling Automatic, AWD/4WD, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA3NC314253
Stock: AL2148P
Certified Pre-Owned: No
Listed since: 04-15-2025 - 26,152 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)
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Located in Orland Park, IL / 298 miles away from Des Moines, IA
Nightfall Mica 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V BOUGHT HERE SERVICED HERE!, LOCAL TRADE!, ONE OWNER!, GREAT VEHICLE HISTORY!, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC338996
Stock: LX06191
Certified Pre-Owned: Yes
Listed since: 04-22-2025- $45,442fair price$717 above market
- 24,846 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Zeigler Subaru of Lafayette (362 mi away)
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Located in Lafayette, IN / 362 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price! 2022 Lexus Nebula Gray Pearl AWD RX 350 F Sport Handling 8-Speed Automatic Odometer is 20774 miles below market ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC347522
Stock: 3920LP
Certified Pre-Owned: No
Listed since: 04-02-2025 - New Listing$43,500fair price$292 above market
- 37,684 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Gregg Young Toyota of Columbus (193 mi away)
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Located in Columbus, NE / 193 miles away from Des Moines, IA
A dynamic daily driver, our Accident Free 2022 Lexus RX 350 AWD has deluxe details and a dramatic Nightfall Mica design! Motivated by a 3.5 Liter V6 d...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDA0NC309450
Stock: 14U1247
Certified Pre-Owned: No
Listed since: 06-10-2025 - $40,000fair price$1,114 below market
- 69,399 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Louisville (487 mi away)
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Located in Louisville, KY / 487 miles away from Des Moines, IA
2022 Lexus RX 350 Clean CARFAX. **UNIQUE OPPORTUNITY**, **LEXUS OF A LIFETIME**, **BLUETOOTH**, **ELECTRONIC STABILITY CONTROL**, **FUEL EFFICIENT**, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC335105
Stock: C088339A
Certified Pre-Owned: Yes
Listed since: 05-20-2025 - $45,990fair price$7 below market
- 31,234 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (321 mi away)
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Located in Merrillville, IN / 321 miles away from Des Moines, IA
UNLIMITED MILE COMPREHENSIVE WARRANTY THRU 12/23/2027!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED STEERING WHEEL!, INTUITIVE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTJHZMDA7N2058070
Stock: PM2741
Certified Pre-Owned: Yes
Listed since: 05-28-2025 - 25,775 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Poquet Auto Sales (234 mi away)
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Located in Golden Valley, MN / 234 miles away from Des Moines, IA
Navigation, Moonroof, Leather, Heated & Ventilated Front Seats, Adaptive Cruise, BLIS, Lane Keep Assist, Apple CarPlay, Android Auto, 20" Alloy Wheels...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA8NC310687
Stock: 24251934
Certified Pre-Owned: No
Listed since: 04-26-2025- $47,940fair price$1,322 above market
- 21,442 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (265 mi away)
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Located in Manchester, MO / 265 miles away from Des Moines, IA
Panoramic View Monitor, L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Leather Seats, Backup Camera, Power Sunroof, Heated/Ventilated seats, Premi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC348067
Stock: 35372A
Certified Pre-Owned: Yes
Listed since: 05-30-2025 - Price Drop$44,100fair price$76 above market
- 24,129 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (308 mi away)
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Located in Milwaukee, WI / 308 miles away from Des Moines, IA
Heated steering wheel!Heated and ventilated seats!Power rear door with kick sensor!Certified. CARFAX One-Owner. Clean CARFAX. Nori Green Pearl ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC337626
Stock: L20939A
Certified Pre-Owned: Yes
Listed since: 06-01-2025 - Price Drop$33,741fair price$717 above market
- 72,742 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Elgin Hyundai (279 mi away)
- Five Star Dealer
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Located in Bartlett, IL / 279 miles away from Des Moines, IA
Boasts 26 Highway MPG and 19 City MPG! This Lexus RX delivers a Regular Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Wheels: 18...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9LC212310
Stock: WG1130
Certified Pre-Owned: No
Listed since: 05-17-2025 - New Listing$41,990fair price$435 below market
- 55,126 miles
- No accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (321 mi away)
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Located in Merrillville, IN / 321 miles away from Des Moines, IA
Green 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24VRecent Arrival! 19/26 City/Highway MPGVisit our showroom and find out why Lexus of Merri...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC343700
Stock: PM2747
Certified Pre-Owned: No
Listed since: 06-10-2025 - Price Drop$40,499fair price$1,057 above market
- 38,819 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (233 mi away)
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Located in Wayzata, MN / 233 miles away from Des Moines, IA
Treat yourself to Lexus Certified ownership privileges:161-point inspection by expert Lexus technicians ensures exemplary condition24/7 Roadside As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3LC236148
Stock: PRS478
Certified Pre-Owned: Yes
Listed since: 06-04-2025 - $43,499fair price$1,493 above market
- 42,993 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Maplewood (238 mi away)
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Located in Maplewood, MN / 238 miles away from Des Moines, IA
L/Certified by Lexus, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, Parking Assist Sensors, Pre-Collisio...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC344561
Stock: PJR19425
Certified Pre-Owned: Yes
Listed since: 05-23-2025 - Price Drop$38,500fair price$777 above market
- 39,316 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lakeside Automotive Group (393 mi away)
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Located in Spring Lake, MI / 393 miles away from Des Moines, IA
2020 Lexus RX 350 Black CARFAX One-Owner. Odometer is 15498 miles below market average! ***CLEAN CARFAX***, ***ONE OWNER***, RX 350, 3.5L V6 DOHC 24V,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDA6LC239403
Stock: 8269
Certified Pre-Owned: No
Listed since: 04-12-2025 - Price Drop$45,986fair price$732 below market
- 18,310 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Briggs Supercenter Manhattan (234 mi away)
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Located in Manhattan, KS / 234 miles away from Des Moines, IA
This 2022 Lexus RX RX 350, comes in exterior with interior. 18310 miles. Stock Number ARCTB0085 Important Package InformationSafety and Security Wi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC360091
Stock: ARCTB0085
Certified Pre-Owned: No
Listed since: 05-27-2025 - $40,995fair price$373 above market
- 55,362 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Arlington (290 mi away)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 350 F Sport Automatic, Backup Camera, BlindSpot Detection, Bluetooth, Hard to find Vehicle this nice for this Value!, Heated ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2SZMAA6NC220233
Stock: AL2175P
Certified Pre-Owned: Yes
Listed since: 05-13-2025 - New Listing$36,625fair price$208 below market
- 52,173 miles
- No accidents, 3 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Jaguar Oklahoma City (465 mi away)
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Located in Oklahoma City, OK / 465 miles away from Des Moines, IA
Land Rover Jaguar Oklahoma City is proud to be an automotive leader in our area. Since opening our doors, Land Rover Jaguar Oklahoma City has kept a f...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4LC229127
Stock: SA287344B
Certified Pre-Owned: No
Listed since: 06-08-2025 - Price Drop$44,970fair price$648 above market
- 17,780 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Tom Kadlec Honda (177 mi away)
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Located in Rochester, MN / 177 miles away from Des Moines, IA
Lexus RX 350 3.5L V6 DOHC 24V TRADED HERE, AWD, Parchment Artificial Leather, Air Conditioning, AM/FM radio: SiriusXM, Apple CarPlay/Android Auto, Aut...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7NC325286
Stock: P11874A
Certified Pre-Owned: No
Listed since: 05-21-2025 - $36,500fair price$316 below market
- 46,704 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (308 mi away)
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Located in Milwaukee, WI / 308 miles away from Des Moines, IA
Navigation system!Touch-free power rear door with kick sensor!Heated leather steering wheel!Heated and ventilated front seats!Certified. CARF...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3LC244878
Stock: PRS7985
Certified Pre-Owned: Yes
Listed since: 05-08-2025 
Photos not available$45,490fair price$415 above market- 30,085 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (321 mi away)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
2 YEAR/UNLIMITED MILE COMPREHENSIVE WARRANTY!, PANORAMIC VIEW MONITOR!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED STEERING W...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC358543
Stock: PM2744
Certified Pre-Owned: Yes
Listed since: 06-03-2025
Showing 64 - 84 out of 1,779 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,952 | $36,153 | $38,449 |
| Clean | $33,500 | $35,653 | $37,896 |
| Average | $32,746 | $34,818 | $36,974 |
| Rough | $31,766 | $33,733 | $35,777 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $42,067. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 42,567. Based on the average mileage of 42,567 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $32,746.
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